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• Activity deltas table
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Motif ID: PITX1..3.p2

Z-value: 3.286

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_92371558	7.468	NM_001195684	TGFBR3	transforming growth factor, beta receptor III
chr15_+_29077439	5.819
chr19_-_9731883	5.373	NM_152289	ZNF561	zinc finger protein 561
chr12_-_117537090	5.349	NM_001168325 NM_017899	TESC	tescalcin
chr3_+_186739643	4.641	NM_003032	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr11_+_62104882	4.388		ASRGL1	asparaginase like 1
chr15_-_23115243	4.340		LOC283683	uncharacterized LOC283683
chr16_+_29471206	4.317	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_+_26400503	4.272	NM_001199837	SNX10	sorting nexin 10
chr1_+_114496498	4.261	NM_181358	HIPK1	homeodomain interacting protein kinase 1
chr16_+_29690328	3.776	NM_014298	QPRT	quinolinate phosphoribosyltransferase
chr16_+_30210548	3.542	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr6_-_31763551	3.429	NM_006295	VARS	valyl-tRNA synthetase
chr8_-_145642250	3.399	NM_130849	SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr2_+_219283809	3.389	NM_007127	VIL1	villin 1
chrX_+_9431314	3.179	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chrX_-_16730669	3.108	NM_175859 NM_019857	CTPS2	CTP synthase II
chrX_-_129272014	3.086	NM_001130846	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr11_-_118213321	3.048	NM_000732 NM_001040651	CD3D	CD3d molecule, delta (CD3-TCR complex)
chr6_-_44233499	2.993	NM_004556	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr17_-_64225496	2.939	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chrX_-_2882288	2.914	NM_000047	ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chr12_-_8043743	2.870		SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr10_-_70231729	2.870	NM_001080449	DNA2	DNA replication helicase 2 homolog (yeast)
chr8_-_38008332	2.862	NM_000349	STAR	steroidogenic acute regulatory protein
chrX_+_198060	2.774	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chrY_+_148060	2.768	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chr7_-_100231135	2.750	NM_001206855	TFR2	transferrin receptor 2
chr19_+_35773409	2.739	NM_021175	HAMP	hepcidin antimicrobial peptide
chr11_+_22696318	2.622	NM_005256	GAS2	growth arrest-specific 2
chr12_-_122296619	2.560	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr1_-_16134192	2.556	NM_001089591	UQCRHL	ubiquinol-cytochrome c reductase hinge protein-like
chr2_+_38893051	2.433	NM_138801	GALM	galactose mutarotase (aldose 1-epimerase)
chrX_+_52238809	2.362	NM_001097597 NM_001097598 NM_001097604 NM_001097605 NM_001097592 NM_001097593 NM_001097594 NM_001097596 NM_020411 NM_133430	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr17_-_62097937	2.335	NM_001099786 NM_001099787 NM_001099788 NM_001099789	ICAM2	intercellular adhesion molecule 2
chr19_+_45409003	2.333	NM_000041	APOE	apolipoprotein E
chr1_+_39922262	2.301		MACF1	microtubule-actin crosslinking factor 1
chr13_+_50202434	2.273	NM_138450	ARL11	ADP-ribosylation factor-like 11
chr16_+_230332	2.243	NM_005331	HBQ1	hemoglobin, theta 1
chr17_+_4675175	2.217	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr17_-_81006406	2.172		B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr1_+_28832454	2.118	NM_001048199	RCC1	regulator of chromosome condensation 1
chr1_-_150738232	2.099		CTSS	cathepsin S
chr6_-_150057659	2.098		NUP43	nucleoporin 43kDa
chr17_-_38821286	2.096	NM_152349	KRT222	keratin 222
chr8_+_42948660	2.088
chr17_-_39684585	2.082	NM_002276	KRT19	keratin 19
chr16_-_32199406	2.073		LOC100289574	hect domain and RLD 2 pseudogene
chr19_-_13213513	2.067		LYL1	lymphoblastic leukemia derived sequence 1
chr19_-_39826676	2.042	NM_004877	GMFG	glia maturation factor, gamma
chr6_-_31774725	2.037	NM_021177	LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_-_27357288	2.024		PREB	prolactin regulatory element binding
chr16_+_32752634	2.003		LOC100289574	hect domain and RLD 2 pseudogene
chr1_-_150738292	1.997	NM_001199739 NM_004079	CTSS	cathepsin S
chr2_-_96950421	1.986		SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)
chr15_-_58306185	1.975	NM_170697	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chrX_+_52780279	1.967	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chr19_-_39826625	1.947		GMFG	glia maturation factor, gamma
chr2_+_97001463	1.920	NM_015341	NCAPH	non-SMC condensin I complex, subunit H
chr16_+_20775311	1.915	NM_005622 NM_202000	ACSM3	acyl-CoA synthetase medium-chain family member 3
chrX_-_52683949	1.895	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr16_+_12058963	1.893	NM_001192	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr11_-_107729913	1.889	NM_017515	SLC35F2	solute carrier family 35, member F2
chrX_+_7810302	1.876	NM_013452	VCX	variable charge, X-linked
chrX_-_137949716	1.869	NM_001139502	FGF13	fibroblast growth factor 13
chr11_+_62104773	1.862	NM_001083926 NM_025080	ASRGL1	asparaginase like 1
chr12_-_54689536	1.851	NM_006163	NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr5_+_139889635	1.837
chr4_-_40517913	1.825	NM_019027	RBM47	RNA binding motif protein 47
chr8_-_145642226	1.818		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr3_-_178969644	1.807	NM_171830	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr2_-_74692534	1.786	NM_001146158 NM_006302	MOGS	mannosyl-oligosaccharide glucosidase
chr2_-_27357519	1.777	NM_013388	PREB	prolactin regulatory element binding
chr9_+_131217433	1.771	NM_153436	ODF2	outer dense fiber of sperm tails 2
chrX_-_48216100	1.771	NM_021014 NM_175711	SSX3	synovial sarcoma, X breakpoint 3
chr1_+_15990300	1.770
chr8_-_124428589	1.769		ATAD2	ATPase family, AAA domain containing 2
chrX_+_52511760	1.769	NM_001097597 NM_001097598 NM_001097604 NM_001097605 NM_001097592 NM_001097593 NM_001097594 NM_001097596 NM_020411 NM_133430	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chrX_-_52545987	1.764	NM_001097598 NM_001097597 NM_001097605 NM_001097604 NM_001097593 NM_001097592 NM_001097596 NM_001097594 NM_133430 NM_020411	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chrX_-_118726852	1.759	NM_001173488	NKRF	NFKB repressing factor
chr6_+_16129285	1.748	NM_013262	MYLIP	myosin regulatory light chain interacting protein
chr8_-_94753211	1.746	NM_203390	RBM12B	RNA binding motif protein 12B
chr11_-_62607627	1.741	NM_018093	WDR74	WD repeat domain 74
chrX_-_52260153	1.739	NM_001097598 NM_001097597 NM_001097605 NM_001097604 NM_001097593 NM_001097592 NM_001097596 NM_001097594 NM_133430 NM_020411	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr19_+_860615	1.736		CFD	complement factor D (adipsin)
chrX_-_52533093	1.729	NM_001097598 NM_001097597 NM_001097605 NM_001097604 NM_001097593 NM_001097592 NM_001097596 NM_001097594 NM_133430 NM_020411	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr16_-_75019007	1.726	NM_030581	WDR59	WD repeat domain 59
chr2_-_74692501	1.719		MOGS	mannosyl-oligosaccharide glucosidase
chr20_+_361272	1.692	NM_021158	TRIB3	tribbles homolog 3 (Drosophila)
chr19_-_13068033	1.664	NM_052850	GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr11_+_118955569	1.653	NM_000190	HMBS	hydroxymethylbilane synthase
chr19_-_12997956	1.652	NM_006563	KLF1	Kruppel-like factor 1 (erythroid)
chr19_-_48744276	1.646	NM_001184900	CARD8	caspase recruitment domain family, member 8
chr6_+_31598366	1.640		PRRC2A	proline-rich coiled-coil 2A
chr6_-_32098051	1.628	NM_022110	FKBPL	FK506 binding protein like
chr16_+_29690464	1.625		QPRT	quinolinate phosphoribosyltransferase
chr3_-_178969402	1.625	NM_014407	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_-_141719188	1.617	NM_001178140	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_70529142	1.615	NM_032822	FAM136A	family with sequence similarity 136, member A
chr16_-_28621279	1.613	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr16_+_67001377	1.613	NM_001185176	CES3	carboxylesterase 3
chr2_-_99279935	1.613	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_27357515	1.608		PREB	prolactin regulatory element binding
chr2_-_27357486	1.593		PREB	prolactin regulatory element binding
chr7_-_99699426	1.590	NM_005916	MCM7	minichromosome maintenance complex component 7
chr17_+_76210276	1.581	NM_001012270 NM_001012271 NM_001168	BIRC5	baculoviral IAP repeat containing 5
chr17_+_76210329	1.569		BIRC5	baculoviral IAP repeat containing 5
chr22_+_21128378	1.568	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr1_-_151345156	1.538	NM_003944	SELENBP1	selenium binding protein 1
chr19_+_55476651	1.533	NM_001174081	NLRP2	NLR family, pyrin domain containing 2
chrX_-_105282714	1.532	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_+_73624328	1.526		LAT2	linker for activation of T cells family, member 2
chr19_-_47735858	1.501	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr7_+_73624347	1.494		LAT2	linker for activation of T cells family, member 2
chr22_-_42336222	1.487	NM_001110215	CENPM	centromere protein M
chr16_+_72097124	1.483	NM_020995	HPR	haptoglobin-related protein
chr9_-_19127462	1.475		PLIN2	perilipin 2
chr6_-_31619481	1.464
chr15_+_45315301	1.457	NM_003104	SORD	sorbitol dehydrogenase
chr3_-_182880463	1.457	NM_014398	LAMP3	lysosomal-associated membrane protein 3
chr1_-_150738255	1.447		CTSS	cathepsin S
chr2_+_97308473	1.446	NM_001113382	FER1L5	fer-1-like 5 (C. elegans)
chr15_-_65412175	1.443		PDCD7	programmed cell death 7
chr2_-_197664335	1.438	NM_001206774 NM_012086	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa
chr11_-_73693883	1.432	NM_003355	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr6_-_2903461	1.426	NM_004155	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr7_+_99070428	1.421		ZNF789	zinc finger protein 789
chr7_-_99680358	1.416		ZNF3	zinc finger protein 3
chr12_-_57146081	1.406	NM_000946	PRIM1	primase, DNA, polypeptide 1 (49kDa)
chr6_+_16129321	1.404		MYLIP	myosin regulatory light chain interacting protein
chr3_+_42632341	1.391		SS18L2	synovial sarcoma translocation gene on chromosome 18-like 2
chr4_-_23891608	1.387	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr9_-_19127494	1.363	NM_001122	PLIN2	perilipin 2
chr16_-_28634873	1.360	NM_177536	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr16_+_28943259	1.351	NM_001178098 NM_001770	CD19	CD19 molecule
chr12_-_123706393	1.348	NM_022782	MPHOSPH9	M-phase phosphoprotein 9
chr22_-_37975937	1.341	NM_006498	LGALS2	lectin, galactoside-binding, soluble, 2
chr10_-_7661613	1.341	NM_032817	ITIH5	inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_-_103245468	1.340	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr1_+_12079298	1.338	NM_021933	MIIP	migration and invasion inhibitory protein
chr5_+_132406080	1.327		HSPA4	heat shock 70kDa protein 4
chr12_-_123834984	1.324	NM_001167856 NM_018183	SBNO1	strawberry notch homolog 1 (Drosophila)
chr19_+_45449228	1.317	NM_000483	APOC2	apolipoprotein C-II
chr9_-_116138340	1.317	NM_031219	HDHD3	haloacid dehalogenase-like hydrolase domain containing 3
chr12_+_7023490	1.316	NM_001975	ENO2	enolase 2 (gamma, neuronal)
chr6_-_44233244	1.314		NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr14_-_23426356	1.314		HAUS4	HAUS augmin-like complex, subunit 4
chr14_-_55650348	1.309		DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr2_-_128615691	1.308		POLR2D	polymerase (RNA) II (DNA directed) polypeptide D
chr2_+_38893238	1.300		GALM	galactose mutarotase (aldose 1-epimerase)
chr16_-_28608367	1.297	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr12_+_54892567	1.297	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr3_+_42632297	1.286	NM_016305	SS18L2	synovial sarcoma translocation gene on chromosome 18-like 2
chr19_-_12792676	1.284		DHPS	deoxyhypusine synthase
chr17_-_8113862	1.279	NM_004217	AURKB	aurora kinase B
chr7_-_99680170	1.277
chr1_-_32385258	1.276	NM_001195100 NM_001195101	PTP4A2	protein tyrosine phosphatase type IVA, member 2
chr1_+_114493766	1.271	NM_198269	HIPK1	homeodomain interacting protein kinase 1
chr6_-_31763473	1.267		VARS	valyl-tRNA synthetase
chr3_+_127317271	1.264		MCM2	minichromosome maintenance complex component 2
chr7_-_1595746	1.262	NM_001097620	TMEM184A	transmembrane protein 184A
chr3_+_127317274	1.252		MCM2	minichromosome maintenance complex component 2
chr1_+_246887377	1.248	NM_016002	SCCPDH	saccharopine dehydrogenase (putative)
chr17_+_18768781	1.243	NM_001243940	PRPSAP2	phosphoribosyl pyrophosphate synthetase-associated protein 2
chr4_-_46911223	1.239	NM_130902	COX7B2	cytochrome c oxidase subunit VIIb2
chr6_+_34724870	1.234	NM_003093	SNRPC	small nuclear ribonucleoprotein polypeptide C
chr16_+_88870214	1.232		CDT1	chromatin licensing and DNA replication factor 1
chr14_-_23426265	1.225	NM_001166269 NM_001166270 NM_017815	HAUS4	HAUS augmin-like complex, subunit 4
chr11_-_73693820	1.224		UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr19_+_50431958	1.221	NM_012068	ATF5	activating transcription factor 5
chr6_-_74161978	1.215		MB21D1	Mab-21 domain containing 1
chr17_+_71229357	1.214		C17orf80	chromosome 17 open reading frame 80
chr15_-_75249774	1.212	NM_017793	RPP25	ribonuclease P/MRP 25kDa subunit
chr11_+_67160775	1.211	NM_001243224	RAD9A	RAD9 homolog A (S. pombe)
chr16_+_88870185	1.210	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr7_+_99070513	1.210	NM_001013258 NM_213603	ZNF789	zinc finger protein 789
chr19_+_1071208	1.208		HMHA1	histocompatibility (minor) HA-1
chr7_+_73868397	1.206		GTF2IRD1	GTF2I repeat domain containing 1
chr7_+_73624086	1.206	NM_014146 NM_032463 NM_032464	LAT2	linker for activation of T cells family, member 2
chr19_-_11639929	1.203	NM_001142464 NM_001142465 NM_016581	ECSIT	ECSIT homolog (Drosophila)
chr16_-_18798077	1.203
chr12_-_8088629	1.193	NM_006931	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3
chr3_-_57199402	1.190	NM_017563	IL17RD	interleukin 17 receptor D
chr7_-_44614136	1.187	NM_019082	DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr3_+_4535160	1.173		ITPR1	inositol 1,4,5-trisphosphate receptor, type 1
chr16_-_28607694	1.170	NM_177528	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr19_-_49576120	1.165	NM_031886	KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7
chr19_-_12792577	1.145		DHPS	deoxyhypusine synthase
chr17_+_8152594	1.145	NM_012393	PFAS	phosphoribosylformylglycinamidine synthase
chr10_-_44063906	1.145	NM_005674	ZNF239	zinc finger protein 239
chr2_-_201828180	1.144	NM_006190	ORC2	origin recognition complex, subunit 2
chr8_-_17743062	1.135		FGL1	fibrinogen-like 1
chr11_-_46612913	1.129	NM_017749	AMBRA1	autophagy/beclin-1 regulator 1
chr2_-_112641733	1.125	NM_022662	ANAPC1	anaphase promoting complex subunit 1
chrX_+_48242967	1.124	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr3_-_9920633	1.123	NM_022094	CIDEC	cell death-inducing DFFA-like effector c
chr12_+_54891539	1.116		NCKAP1L	NCK-associated protein 1-like
chr1_+_150293916	1.113	NM_004698	PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)
chr17_+_17380264	1.113	NM_018019	MED9	mediator complex subunit 9
chr2_+_219575507	1.112	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.15	3.47e-02	GO:0005622	intracellular
1.23	3.89e-02	GO:0043227	membrane-bounded organelle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
53.30	2.01e-03	GO:0004062	aryl sulfotransferase activity