Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 1.732


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RFX5chr1_-_151319717-0.674.6e-03Click!
RFXAPchr13_+_37393306-0.611.3e-02Click!
RFX2chr19_-_61104910.351.8e-01Click!
RFX1chr19_-_14117096,
chr19_-_14116875
0.302.6e-01Click!
RFXANKchr19_+_19303007-0.107.2e-01Click!
RFX3chr9_-_3525973-0.087.6e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_133938819 4.810 NM_001205329
NM_032801
JAM3

junctional adhesion molecule 3

chr11_+_133938965 3.861 JAM3
junctional adhesion molecule 3
chr2_-_175869910 2.781 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr14_+_105941061 2.587 NM_001312
CRIP2
cysteine-rich protein 2
chr15_+_71184781 2.478 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chrX_+_135251454 2.305 NM_001159704
FHL1
four and a half LIM domains 1
chrX_+_135251795 2.274 NM_001167819
FHL1
four and a half LIM domains 1
chr15_-_71184611 2.134 NM_020147
THAP10
THAP domain containing 10
chr14_-_74180341 1.794 NM_006029
PNMA1
paraneoplastic antigen MA1
chr3_-_123339423 1.776 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr14_+_100259445 1.774 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr4_-_156297973 1.612 MAP9
microtubule-associated protein 9
chr12_-_89746244 1.566 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr16_-_69760354 1.478 NQO1
NAD(P)H dehydrogenase, quinone 1
chr15_+_96873845 1.469 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_-_179780314 1.436 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr4_-_156297944 1.403 MAP9
microtubule-associated protein 9
chr20_+_43991739 1.394 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 readthrough
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr16_-_69760367 1.382 NQO1
NAD(P)H dehydrogenase, quinone 1
chr7_+_130131921 1.364 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr12_-_89745997 1.359 DUSP6
dual specificity phosphatase 6
chr16_+_57278979 1.345 NM_012106
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr15_+_101420032 1.293 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr1_-_169336999 1.293 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr3_-_123339178 1.272 MYLK
myosin light chain kinase
chr11_+_102980083 1.253 NM_001080463
NM_001377
DYNC2H1

dynein, cytoplasmic 2, heavy chain 1

chr3_+_154797435 1.223 NM_000902
MME
membrane metallo-endopeptidase
chr20_+_44044706 1.213 NM_001184728
NM_001184729
NM_001184730
NM_015937
PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr5_-_16742336 1.206 MYO10
myosin X
chr19_-_58609606 1.190 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr4_-_156298094 1.180 NM_001039580
MAP9
microtubule-associated protein 9
chr15_+_101420004 1.173 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr12_-_89746238 1.165 DUSP6
dual specificity phosphatase 6
chr17_-_64187814 1.149 NM_145036
NM_001199165
CEP112

centrosomal protein 112kDa

chr22_+_39052628 1.145 NM_001002880
NM_015373
CBY1

chibby homolog 1 (Drosophila)

chr1_+_84630374 1.106 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_+_26662547 1.103 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr3_-_149688886 1.098 PFN2
profilin 2
chr7_-_35077652 1.092 NM_015283
DPY19L1
dpy-19-like 1 (C. elegans)
chr16_-_69760444 1.073 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr20_+_43160435 1.069 NM_007066
NM_181804
NM_181805
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr22_+_39052671 1.066 CBY1
chibby homolog 1 (Drosophila)
chr7_+_150929526 1.064 NM_019015
CHPF2
chondroitin polymerizing factor 2
chr13_+_37006408 1.060 NM_001111045
NM_003914
CCNA1

cyclin A1

chr1_-_59249687 1.058 NM_002228
JUN
jun proto-oncogene
chr17_-_5404304 1.031 NM_001162371
LOC728392
uncharacterized LOC728392
chr8_+_59465798 1.021 SDCBP
syndecan binding protein (syntenin)
chr6_+_88117689 1.000 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr6_+_52284948 0.992 NM_018100
EFHC1
EF-hand domain (C-terminal) containing 1
chr8_+_59465818 0.989 SDCBP
syndecan binding protein (syntenin)
chr12_+_104680712 0.987 NM_003330
NM_182729
NM_182742
NM_182743
TXNRD1



thioredoxin reductase 1



chr4_+_87515465 0.983 NM_006264
NM_080683
NM_080684
NM_080685
PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr3_-_107941168 0.983 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr8_+_59465727 0.969 NM_001007067
NM_001007068
NM_001007069
NM_001007070
NM_005625
SDCBP




syndecan binding protein (syntenin)




chr16_+_57662301 0.952 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr7_+_65670256 0.951 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr14_-_102771469 0.930 NM_014226
MOK
MOK protein kinase
chr15_+_90792761 0.930 NM_001029964
TTLL13
tubulin tyrosine ligase-like family, member 13
chrX_-_99891690 0.924 NM_003270
TSPAN6
tetraspanin 6
chr9_-_110252045 0.923 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr5_+_34684611 0.890 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr10_+_70748476 0.863 NM_015634
KIAA1279
KIAA1279
chr17_-_61523544 0.851 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr21_+_18885104 0.847 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr1_-_163113938 0.845 RGS5
regulator of G-protein signaling 5
chr17_+_78518742 0.840 RPTOR
regulatory associated protein of MTOR, complex 1
chr7_+_100797685 0.814 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_+_99127146 0.801 NM_015976
NM_152238
SNX7

sorting nexin 7

chr21_+_18885296 0.795 CXADR
coxsackie virus and adenovirus receptor
chr19_-_47354060 0.787 NM_004069
NM_021575
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr3_+_33318911 0.785 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr5_+_92918924 0.783 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_-_110251754 0.778 KLF4
Kruppel-like factor 4 (gut)
chr4_+_153701113 0.712 ARFIP1
ADP-ribosylation factor interacting protein 1
chr6_-_159065739 0.710 NM_006519
DYNLT1
dynein, light chain, Tctex-type 1
chr19_-_15560761 0.708 NM_021241
WIZ
widely interspaced zinc finger motifs
chr11_-_115375065 0.701 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr8_+_120428551 0.696 NM_002514
NOV
nephroblastoma overexpressed gene
chr3_+_158288952 0.694 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr6_+_20402040 0.673 NM_001949
E2F3
E2F transcription factor 3
chr7_-_44228880 0.673 NM_000162
GCK
glucokinase (hexokinase 4)
chr12_+_104681018 0.668 TXNRD1
thioredoxin reductase 1
chr2_+_232063379 0.666 ARMC9
armadillo repeat containing 9
chr19_-_2783332 0.654 NM_003021
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr1_+_78444922 0.642 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr17_+_900329 0.638 NM_013337
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr2_+_183580960 0.638 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr13_-_96294282 0.635 DZIP1
DAZ interacting protein 1
chr1_+_169337193 0.629 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr5_-_149669400 0.624 NM_015981
NM_171825
CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr19_-_2783225 0.617 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr16_-_47494753 0.616 ITFG1
integrin alpha FG-GAP repeat containing 1
chr2_+_232063340 0.612 NM_025139
ARMC9
armadillo repeat containing 9
chr2_+_232063378 0.606 ARMC9
armadillo repeat containing 9
chr19_-_2783313 0.602 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr16_-_47494981 0.599 NM_030790
ITFG1
integrin alpha FG-GAP repeat containing 1
chr11_+_131780537 0.597 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr19_-_50370799 0.596 NM_007254
PNKP
polynucleotide kinase 3'-phosphatase
chr15_-_43785266 0.593 NM_001141979
NM_001141980
TP53BP1

tumor protein p53 binding protein 1

chr6_-_75994496 0.584 TMEM30A
transmembrane protein 30A
chr11_-_10562689 0.581 NM_016422
RNF141
ring finger protein 141
chr1_+_38022514 0.581 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr1_+_84630575 0.575 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr21_-_46707748 0.567 NM_015227
NM_133635
POFUT2

protein O-fucosyltransferase 2

chr3_-_49055916 0.566 NM_001009996
DALRD3
DALR anticodon binding domain containing 3
chr6_-_2842112 0.564 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr13_-_36920491 0.560 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_+_245133067 0.559 NM_032328
EFCAB2
EF-hand calcium binding domain 2
chr7_+_106685007 0.557 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr6_-_2842069 0.557 NM_030666
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr11_-_33795892 0.557 NM_012175
NM_033406
FBXO3

F-box protein 3

chr19_-_46974789 0.545 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr1_+_19923457 0.543 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chr1_+_109656570 0.540 NM_020775
KIAA1324
KIAA1324
chr1_+_203444955 0.539 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_-_46685962 0.538 NM_001243766
POMGNT1
protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase
chr1_-_43637958 0.532 EBNA1BP2
EBNA1 binding protein 2
chr11_-_66112537 0.526 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr6_-_43484701 0.523 NM_015388
YIPF3
Yip1 domain family, member 3
chr7_-_22539795 0.520 NM_001164460
NM_207342
STEAP1B

STEAP family member 1B

chr11_-_62473502 0.511 NM_001130702
NM_032667
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr22_-_43485333 0.502 NM_012263
TTLL1
tubulin tyrosine ligase-like family, member 1
chr10_+_99400441 0.496 NM_018425
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr6_-_75994477 0.495 TMEM30A
transmembrane protein 30A
chr7_-_124405029 0.495 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr6_+_31783280 0.487 NM_005345
HSPA1A
heat shock 70kDa protein 1A
chr5_-_142065586 0.487 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr4_+_153700932 0.486 NM_001025593
NM_001025595
NM_014447
ARFIP1


ADP-ribosylation factor interacting protein 1


chr8_-_101964236 0.486 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr15_-_85197502 0.485 WDR73
WD repeat domain 73
chr15_-_43802666 0.484 NM_005657
TP53BP1
tumor protein p53 binding protein 1
chr16_-_88923233 0.482 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr5_+_148520985 0.481 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr3_-_10362776 0.481 SEC13
SEC13 homolog (S. cerevisiae)
chr2_+_170335948 0.478 NM_152384
BBS5
Bardet-Biedl syndrome 5
chr1_-_44820700 0.478 ERI3
ERI1 exoribonuclease family member 3
chr16_-_88923348 0.477 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr15_-_67546968 0.476 NM_024666
AAGAB
alpha- and gamma-adaptin binding protein
chr1_-_43637969 0.474 NM_006824
NM_001159936
EBNA1BP2

EBNA1 binding protein 2

chr6_-_43484503 0.472 YIPF3
Yip1 domain family, member 3
chr3_-_58563070 0.471 FAM107A
family with sequence similarity 107, member A
chr11_+_61447816 0.470 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr9_+_132815984 0.469 NM_001136557
NM_001136558
NM_020960
GPR107


G protein-coupled receptor 107


chr1_-_114301753 0.466 NM_006608
PHTF1
putative homeodomain transcription factor 1
chr12_+_105501556 0.463


chrX_+_48456552 0.461 WDR13
WD repeat domain 13
chr1_-_114302093 0.460 PHTF1
putative homeodomain transcription factor 1
chr6_-_32163890 0.460 NOTCH4
notch 4
chr8_+_22462286 0.457 KIAA1967
KIAA1967
chr3_+_62304667 0.456 C3orf14
chromosome 3 open reading frame 14
chr12_-_91505541 0.454 NM_002345
LUM
lumican
chr1_-_44820923 0.454 ERI3
ERI1 exoribonuclease family member 3
chr13_+_24463591 0.451 NM_001135816
C1QTNF9B-AS1
C1QTNF9B antisense RNA 1 (non-protein coding)
chr15_-_77363451 0.449 TSPAN3
tetraspanin 3
chr15_-_85197512 0.449 NM_032856
WDR73
WD repeat domain 73
chr6_-_75994631 0.448 NM_001143958
NM_018247
TMEM30A

transmembrane protein 30A

chr3_-_10362837 0.447 NM_183352
SEC13
SEC13 homolog (S. cerevisiae)
chr7_-_102920665 0.446 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr14_+_102829351 0.445 TECPR2
tectonin beta-propeller repeat containing 2
chr16_-_57836380 0.445 NM_001130100
NM_005550
KIFC3

kinesin family member C3

chr12_+_120933916 0.443 DYNLL1
dynein, light chain, LC8-type 1
chr6_+_31783314 0.443 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chrX_+_48456220 0.441 NM_001166426
WDR13
WD repeat domain 13
chr9_+_116356199 0.439 NM_144489
RGS3
regulator of G-protein signaling 3
chr17_-_41856180 0.438 NM_004090
DUSP3
dual specificity phosphatase 3
chr14_-_23058062 0.437 DAD1
defender against cell death 1
chr7_+_138818489 0.435 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr1_-_44820935 0.435 NM_024066
ERI3
ERI1 exoribonuclease family member 3
chr8_+_22462273 0.435 KIAA1967
KIAA1967
chr11_+_8060179 0.433 NM_003320
TUB
tubby homolog (mouse)
chr19_+_3572958 0.431 HMG20B
high mobility group 20B
chr2_-_44588943 0.428 NM_001171603
NM_001171617
PREPL

prolyl endopeptidase-like

chr19_+_39616384 0.428 NM_001014831
NM_001014832
NM_001014834
NM_001014835
NM_005884
PAK4




p21 protein (Cdc42/Rac)-activated kinase 4




chr14_-_23058114 0.427 NM_001344
DAD1
defender against cell death 1
chr6_+_30034931 0.424 NM_021959
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr3_+_130745693 0.423 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr3_-_49761293 0.423 NM_013334
NM_021971
GMPPB

GDP-mannose pyrophosphorylase B

chr12_-_131323616 0.420 NM_001980
NM_194356
STX2

syntaxin 2

chr14_+_74486049 0.420 NM_025057
C14orf45
chromosome 14 open reading frame 45
chr8_-_101964268 0.419 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_-_142065991 0.417 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr5_-_149669187 0.417 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr8_-_98290072 0.417 TSPYL5
TSPY-like 5
chr2_-_47403679 0.415 NM_001743
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr1_-_6052481 0.414 NM_015102
NPHP4
nephronophthisis 4
chr19_-_46974663 0.413 PNMAL1
PNMA-like 1
chr12_+_120933911 0.410 DYNLL1
dynein, light chain, LC8-type 1
chr9_-_34620489 0.409 NM_007234
NM_024348
DCTN3

dynactin 3 (p22)

chr10_-_17243617 0.408 TRDMT1
tRNA aspartic acid methyltransferase 1
chr11_-_64545988 0.406 SF1
splicing factor 1
chr16_-_53737713 0.404 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr8_+_22462267 0.402 KIAA1967
KIAA1967
chrX_+_129473812 0.401 NM_003951
NM_022810
SLC25A14

solute carrier family 25 (mitochondrial carrier, brain), member 14

chr8_+_22462532 0.399 NM_021174
KIAA1967
KIAA1967
chr8_-_98290171 0.397 NM_033512
TSPYL5
TSPY-like 5
chr4_-_170924911 0.394 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr2_-_47403649 0.393 CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr18_+_54318561 0.392 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr1_-_43637788 0.390 EBNA1BP2
EBNA1 binding protein 2
chr21_-_35014013 0.389 NM_145858
CRYZL1
crystallin, zeta (quinone reductase)-like 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.