Motif ID: T.p2

Z-value: 0.537


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tchr6_-_1665821290.467.3e-02Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_152146373 2.382 NM_004688
NMI
N-myc (and STAT) interactor
chr7_-_87849341 1.847 SRI
sorcin
chr14_-_107013474 1.085 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_87849366 1.031 NM_003130
SRI
sorcin
chr1_+_174844655 1.003 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr12_-_52867521 0.999 NM_173086
KRT6C
keratin 6C
chr10_+_70847817 0.866 NM_002727
SRGN
serglycin
chr17_+_34431219 0.849 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr14_-_107113943 0.818 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_107221203 0.818 NM_001008405
BCAP29
B-cell receptor-associated protein 29
chrX_+_128913881 0.782 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_25958192 0.781 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958217 0.779 LGALS9
lectin, galactoside-binding, soluble, 9
chr7_+_107220622 0.765 BCAP29
B-cell receptor-associated protein 29
chr17_+_25958151 0.746 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr10_+_70847857 0.741 SRGN
serglycin
chr17_+_25958245 0.738 LGALS9
lectin, galactoside-binding, soluble, 9
chr22_-_41215251 0.700 NM_006358
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr12_-_52845862 0.700 NM_005555
KRT6B
keratin 6B
chr12_-_53074172 0.670 NM_006121
KRT1
keratin 1
chrX_+_128913897 0.667 SASH3
SAM and SH3 domain containing 3
chr11_-_66112537 0.584 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr15_+_40861509 0.579 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr18_+_54424444 0.538 WDR7
WD repeat domain 7
chr3_+_23851933 0.526 NM_001202476
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr5_+_31799030 0.504 NM_178140
PDZD2
PDZ domain containing 2
chr2_+_33661392 0.496 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_+_25958257 0.481 LGALS9
lectin, galactoside-binding, soluble, 9
chr7_-_16505292 0.478 NM_015464
SOSTDC1
sclerostin domain containing 1
chr7_+_143013218 0.449 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr12_+_113623364 0.431 NM_032848
C12orf52
chromosome 12 open reading frame 52
chr1_+_209941894 0.430 TRAF3IP3
TRAF3 interacting protein 3
chr1_+_26737232 0.423 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr4_-_73434467 0.418 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr17_+_34538464 0.414 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr1_-_117210301 0.406 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chrX_+_16804531 0.401 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr2_-_100722328 0.358 AFF3
AF4/FMR2 family, member 3
chr11_+_117947785 0.351 TMPRSS4
transmembrane protease, serine 4
chr16_+_12058963 0.347 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chrX_+_37639306 0.327 CYBB
cytochrome b-245, beta polypeptide
chr1_+_174843523 0.315 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr15_+_40861491 0.314 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr19_-_14260728 0.302 LPHN1
latrophilin 1
chr11_+_117947726 0.298 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr9_+_75766777 0.294 NM_000700
ANXA1
annexin A1
chr17_-_61523544 0.291 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr10_-_101690655 0.269 DNMBP
dynamin binding protein
chr1_+_26737306 0.268 LIN28A
lin-28 homolog A (C. elegans)
chr11_-_111249902 0.258 POU2AF1
POU class 2 associating factor 1
chr4_-_151936648 0.250 NM_006726
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr21_-_15918635 0.246 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_124806302 0.245 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr11_+_34073188 0.241 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr1_-_114414245 0.238 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr9_+_75766794 0.233 ANXA1
annexin A1
chr16_+_77233348 0.231 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr4_-_145061787 0.226 NM_002099
GYPA
glycophorin A (MNS blood group)
chr21_-_47704166 0.217 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr10_-_23003443 0.213 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr3_-_111314181 0.212 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr12_+_21525801 0.211 NM_000415
IAPP
islet amyloid polypeptide
chr10_+_11047253 0.205 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr11_-_33913835 0.204 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr14_-_106994001 0.204 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr11_-_57195052 0.199 NM_017611
SLC43A3
solute carrier family 43, member 3
chr6_-_32634287 0.192 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chrX_+_100354797 0.191 NM_006733
CENPI
centromere protein I
chr2_-_216003068 0.189 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_16062808 0.185 NM_207348
SLC25A34
solute carrier family 25, member 34
chr16_-_67965754 0.181 NM_001907
CTRL
chymotrypsin-like
chr10_+_11060069 0.177 CELF2
CUGBP, Elav-like family member 2
chr2_-_237172987 0.172 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr1_-_154842725 0.170 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr11_+_60223281 0.164 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr2_-_37544165 0.161 NM_005813
PRKD3
protein kinase D3
chr6_+_26158332 0.161 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr1_-_115124211 0.157 NM_005872
BCAS2
breast carcinoma amplified sequence 2
chr1_-_153029987 0.150 NM_005988
SPRR2A
small proline-rich protein 2A
chr15_-_75918718 0.148 NM_001042588
SNUPN
snurportin 1
chr2_+_234601511 0.148 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr7_+_121513158 0.141 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr2_-_69098502 0.138 NM_014482
BMP10
bone morphogenetic protein 10
chr2_+_176972005 0.137 NM_021192
HOXD11
homeobox D11
chr11_-_120008848 0.137 NM_012101
TRIM29
tripartite motif containing 29
chr17_+_7533452 0.137 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr14_-_106692107 0.135 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr15_-_34502269 0.134 NM_024713
C15orf29
chromosome 15 open reading frame 29
chrX_+_48336379 0.134 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr6_-_31681845 0.130


chr4_-_144940439 0.128 NM_002100
GYPB
glycophorin B (MNS blood group)
chr7_-_5570188 0.128 NM_001101
ACTB
actin, beta
chr5_-_9630462 0.126 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr15_-_80263460 0.126 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr11_-_120008801 0.120 TRIM29
tripartite motif containing 29
chr11_-_120008738 0.119 TRIM29
tripartite motif containing 29
chr5_-_138725544 0.119 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr5_+_42549657 0.117 NM_001242404
GHR
growth hormone receptor
chr7_+_99816870 0.116 NM_024070
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr1_+_156123321 0.116 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr7_-_44180911 0.115 NM_021223
MYL7
myosin, light chain 7, regulatory
chr10_+_94833646 0.115 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr1_-_27953046 0.115 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr2_-_113542970 0.114 NM_000575
IL1A
interleukin 1, alpha
chr3_-_119582422 0.114 GSK3B
glycogen synthase kinase 3 beta
chr1_-_26232890 0.113 NM_001145454
NM_005563
STMN1

stathmin 1

chr14_-_106691698 0.111


chr19_-_11688508 0.111 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr19_-_44285012 0.107 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr19_-_11688441 0.107 ACP5
acid phosphatase 5, tartrate resistant
chr8_+_75736771 0.107 NM_015886
PI15
peptidase inhibitor 15
chr19_-_10514154 0.106 CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr7_+_100027404 0.105 MEPCE
methylphosphate capping enzyme
chr17_+_7465316 0.104 SENP3
SUMO1/sentrin/SMT3 specific peptidase 3
chr2_+_103089761 0.104 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr17_-_61973870 0.103 NM_001317
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chr12_+_96252705 0.101 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr14_-_107078578 0.099


chr3_+_133502876 0.098 NM_021203
SRPRB
signal recognition particle receptor, B subunit
chr17_-_39768939 0.097 NM_005557
KRT16
keratin 16
chr6_-_90062349 0.097 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr10_+_5488521 0.096 NM_005863
NET1
neuroepithelial cell transforming 1
chr12_+_54422193 0.095 NM_004503
HOXC6
homeobox C6
chr17_+_57970442 0.094 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr5_-_134914968 0.093 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr6_+_109762204 0.092 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr4_-_144826659 0.090 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr11_-_118900078 0.089 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr17_+_8214139 0.089 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr6_-_90062439 0.087 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr5_+_42565562 0.087 NM_001242406
GHR
growth hormone receptor
chr1_-_24126031 0.085 NM_001127621
GALE
UDP-galactose-4-epimerase
chr1_-_153067000 0.085 NM_001024209
SPRR2E
small proline-rich protein 2E
chrX_+_133594171 0.084 NM_000194
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr3_-_101395611 0.083 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr1_+_66797775 0.083 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr22_+_22676814 0.083


chr7_-_5568823 0.083 ACTB
actin, beta
chr12_-_51663969 0.082 NM_001033873
NM_001031628
SMAGP

small cell adhesion glycoprotein

chr8_-_74659942 0.080 NM_001164384
STAU2
staufen, RNA binding protein, homolog 2 (Drosophila)
chr17_+_34640030 0.079 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr14_-_106725620 0.077 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr19_+_17638064 0.076 FAM129C
family with sequence similarity 129, member C
chr8_-_74659056 0.075 STAU2
LOC729696
staufen, RNA binding protein, homolog 2 (Drosophila)
uncharacterized LOC729696
chr3_-_58200397 0.075 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr11_-_17191287 0.073 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr6_-_26124130 0.073 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr19_-_44831907 0.072 ZFP112
zinc finger protein 112 homolog (mouse)
chr12_+_54378929 0.072 NM_017409
HOXC10
homeobox C10
chr1_+_35225341 0.071 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr1_-_58716207 0.070 NM_021080
DAB1
disabled homolog 1 (Drosophila)
chr3_-_52443893 0.070 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr6_-_74229094 0.070 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr7_+_116164838 0.069 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr1_-_155231941 0.069 SCAMP3
secretory carrier membrane protein 3
chr6_-_29012951 0.069 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr15_-_34502188 0.068 C15orf29
chromosome 15 open reading frame 29
chr3_+_128532267 0.068


chr12_+_56324945 0.067 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr1_+_112162397 0.067 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chrX_-_6145887 0.067 NM_020742
NLGN4X
neuroligin 4, X-linked
chr1_-_11907741 0.066 NM_006172
NPPA
natriuretic peptide A
chr12_-_7125727 0.066 NM_005768
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr1_-_26233367 0.065 NM_203399
STMN1
stathmin 1
chr9_-_73736513 0.064 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr9_+_134378334 0.063 POMT1
protein-O-mannosyltransferase 1
chr19_+_55591759 0.061 NM_017729
EPS8L1
EPS8-like 1
chr10_+_49514652 0.061 MAPK8
mitogen-activated protein kinase 8
chr6_+_83072922 0.060 NM_006670
TPBG
trophoblast glycoprotein
chr16_-_2336874 0.060


chr15_+_60296506 0.060 FOXB1
forkhead box B1
chr10_-_35363167 0.060 NM_001198778
NM_001198779
CUL2

cullin 2

chr5_-_39203061 0.060 FYB
FYN binding protein
chr2_+_219081864 0.059 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_200322699 0.058 NM_001172509
SATB2
SATB homeobox 2
chr15_+_60296420 0.058 NM_012182
FOXB1
forkhead box B1
chr2_-_219031646 0.057 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr9_-_14722669 0.056 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr15_-_43559054 0.056 NM_004245
NM_201631
TGM5

transglutaminase 5

chr7_+_2282440 0.056 NM_198953
NM_198954
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr17_+_7155371 0.055 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr14_-_107218786 0.055 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr13_-_24007822 0.053 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr13_+_77566043 0.052 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr3_+_40428672 0.052 NM_001248
ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
chr15_+_91411884 0.051 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr2_+_233320832 0.051 NM_001631
ALPI
alkaline phosphatase, intestinal
chr17_-_61996135 0.051 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr17_+_39868577 0.050 NM_000805
GAST
gastrin
chr1_-_37499708 0.050 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr13_+_109281569 0.049 NM_001198950
MYO16
myosin XVI
chr3_+_25469749 0.049 NM_016152
RARB
retinoic acid receptor, beta
chr22_-_51016343 0.049 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chrX_+_100663229 0.049 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_+_7461591 0.049 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr7_+_100027253 0.049 NM_019606
MEPCE
methylphosphate capping enzyme
chr7_-_752083 0.049 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr8_+_103563847 0.048 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr6_-_35696359 0.046 NM_001145775
FKBP5
FK506 binding protein 5
chr19_-_10514185 0.046 CDC37
cell division cycle 37 homolog (S. cerevisiae)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
105.57 2.95e-04 GO:0003823 antigen binding