Motif ID: UCACAUU

Z-value: 1.277


Mature miRNA associated with seed UCACAUU:

NamemiRBase Accession
hsa-miR-23a MIMAT0000078
hsa-miR-23b MIMAT0000418
hsa-miR-23c MIMAT0018000



Activity profile for motif UCACAUU.

activity profile for motif UCACAUU


Sorted Z-values histogram for motif UCACAUU

Sorted Z-values for motif UCACAUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_92351613 4.356 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr1_-_92371558 3.652 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr1_-_32801606 2.073 NM_023009
MARCKSL1
MARCKS-like 1
chr16_-_89043215 1.779 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_-_89007605 1.663 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr4_-_174254730 1.519 NM_001130689
HMGB2
high mobility group box 2
chr3_-_138665981 1.452 NM_023067
FOXL2
forkhead box L2
chr4_-_174255454 1.304 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr2_-_101034049 1.239 NM_004854
CHST10
carbohydrate sulfotransferase 10
chr17_-_40428391 1.207 NM_012448
STAT5B
signal transducer and activator of transcription 5B
chr2_-_188312872 1.146 NM_005795
CALCRL
calcitonin receptor-like
chr9_-_138987096 1.140 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr9_+_101569933 1.125 NM_024642
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr2_-_200329810 1.051 NM_001172517
SATB2
SATB homeobox 2
chr2_-_200322699 1.021 NM_001172509
SATB2
SATB homeobox 2
chr6_-_39197225 1.008 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr1_+_66797775 1.008 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_+_119215240 0.959 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_+_66458389 0.948 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chrY_+_16634487 0.933 NM_001206850
NLGN4Y
neuroligin 4, Y-linked
chr1_+_66258192 0.922 NM_001037341
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_200335988 0.901 NM_015265
SATB2
SATB homeobox 2
chr1_-_32403975 0.896 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr17_+_34948213 0.865 NM_024308
DHRS11
dehydrogenase/reductase (SDR family) member 11
chr7_+_98476084 0.863 NM_001244580
NM_003496
TRRAP

transformation/transcription domain-associated protein

chr1_+_66258855 0.852 NM_002600
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_112312392 0.813 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chrY_+_16635625 0.707 NM_014893
NLGN4Y
neuroligin 4, Y-linked
chr4_+_38665587 0.699 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr11_-_86666211 0.695 NM_012193
FZD4
frizzled family receptor 4
chr4_-_140060601 0.686 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr11_-_66115016 0.672 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr8_-_93111915 0.668 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_32385258 0.664 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr22_+_45560529 0.648 NM_153645
NUP50
nucleoporin 50kDa
chr15_-_58358120 0.637 NM_001206897
NM_003888
NM_170696
ALDH1A2


aldehyde dehydrogenase 1 family, member A2


chr12_+_104680712 0.616 NM_003330
NM_182729
NM_182742
NM_182743
TXNRD1



thioredoxin reductase 1



chr4_+_154387450 0.612 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr1_-_245027808 0.598 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr12_-_123834984 0.587 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr2_-_208634051 0.585 NM_003468
FZD5
frizzled family receptor 5
chr1_+_63833260 0.575 NM_013339
ALG6
asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr1_+_179923870 0.567 NM_014810
CEP350
centrosomal protein 350kDa
chr5_+_162864571 0.566 NM_004060
NM_199246
CCNG1

cyclin G1

chr17_-_74449272 0.550 NM_022066
UBE2O
ubiquitin-conjugating enzyme E2O
chr18_+_60190657 0.548 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr8_-_93029864 0.537 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107881 0.530 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr12_-_10766130 0.517 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr10_+_11047253 0.513 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr15_-_58306185 0.496 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_28099682 0.487 NM_177424
STX12
syntaxin 12
chr6_+_87865261 0.483 NM_015021
ZNF292
zinc finger protein 292
chrX_-_124097601 0.473 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1 (Drosophila)


chr12_+_122242580 0.471 NM_015048
SETD1B
SET domain containing 1B
chr12_+_104609501 0.470 NM_001093771
TXNRD1
thioredoxin reductase 1
chr10_+_134351272 0.467 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr11_-_76091866 0.465 NM_004705
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr10_-_30348433 0.465 NM_020848
KIAA1462
KIAA1462
chr13_+_73301980 0.464 NM_024808
BORA
bora, aurora kinase A activator
chr8_-_93075190 0.450 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_77593506 0.450 NM_024721
ZFHX4
zinc finger homeobox 4
chr1_-_27816676 0.442 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr9_+_4490193 0.441 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr9_-_16870719 0.427 NM_017637
BNC2
basonuclin 2
chr8_-_93115453 0.417 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr16_-_52580805 0.409 NM_001080430
TOX3
TOX high mobility group box family member 3
chr8_-_93107442 0.409 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr4_-_140005464 0.408 NM_006874
ELF2
E74-like factor 2 (ets domain transcription factor)
chr15_-_60884615 0.404 NM_134262
RORA
RAR-related orphan receptor A
chr15_-_60919642 0.402 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr12_-_56652118 0.398 NM_173595
ANKRD52
ankyrin repeat domain 52
chrX_-_110513750 0.396 NM_014289
CAPN6
calpain 6
chr5_+_34684611 0.394 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr2_+_66662516 0.394 NM_002398
MEIS1
Meis homeobox 1
chr11_+_124609775 0.394 NM_001126181
NM_006176
NRGN

neurogranin (protein kinase C substrate, RC3)

chr11_+_32914359 0.393 NM_001076786
QSER1
glutamine and serine rich 1
chr15_-_61521478 0.390 NM_134261
RORA
RAR-related orphan receptor A
chr5_+_34656595 0.390 NM_001145520
RAI14
retinoic acid induced 14
chr10_-_99094427 0.388 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr16_-_52581713 0.380 NM_001146188
TOX3
TOX high mobility group box family member 3
chr10_+_11059854 0.380 NM_006561
CELF2
CUGBP, Elav-like family member 2
chrX_-_129244471 0.380 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chr2_+_135676387 0.375 NM_001241
NM_058241
CCNT2

cyclin T2

chr4_+_144257982 0.374 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr4_+_87856152 0.372 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr4_+_87928083 0.370 NM_005935
AFF1
AF4/FMR2 family, member 1
chr4_-_129209983 0.364 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr2_-_70475563 0.363 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr1_-_225616556 0.360 NM_194442
LBR
lamin B receptor
chr1_-_225615787 0.359 NM_002296
LBR
lamin B receptor
chr10_-_101989342 0.358 NM_001278
CHUK
conserved helix-loop-helix ubiquitous kinase
chr14_+_73525187 0.351 NM_021239
RBM25
RNA binding motif protein 25
chr9_+_100263818 0.343 NM_003275
TMOD1
tropomodulin 1
chr2_-_172087823 0.343 NM_001136554
TLK1
tousled-like kinase 1
chr1_+_167298280 0.342 NM_001198783
POU2F1
POU class 2 homeobox 1
chr6_+_163835668 0.340 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr15_+_48010685 0.340 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr4_-_53525316 0.336 NM_022832
USP46
ubiquitin specific peptidase 46
chr4_-_40631846 0.335 NM_001098634
RBM47
RNA binding motif protein 47
chr22_+_45559725 0.327 NM_007172
NUP50
nucleoporin 50kDa
chr12_+_98909331 0.325 NM_001032283
NM_001032284
NM_003276
TMPO


thymopoietin


chr16_+_58534045 0.324 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr2_+_24807345 0.324 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr2_-_171923482 0.321 NM_001136555
TLK1
tousled-like kinase 1
chr10_+_31610063 0.320 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr10_+_31608097 0.317 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chrX_-_129244652 0.311 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr5_+_34656367 0.301 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr7_-_14025826 0.299 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chrX_+_70315637 0.299 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr11_+_94277005 0.296 NM_002033
PIWIL4
FUT4
piwi-like 4 (Drosophila)
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chrX_+_115567746 0.295 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr1_+_26798901 0.294 NM_005517
HMGN2
high mobility group nucleosomal binding domain 2
chr20_+_39657461 0.294 NM_003286
TOP1
topoisomerase (DNA) I
chr17_-_29151724 0.291 NM_015986
CRLF3
cytokine receptor-like factor 3
chr9_+_100263461 0.289 NM_001166116
TMOD1
tropomodulin 1
chr5_-_136834887 0.289 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr4_+_1894508 0.279 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr5_-_88199868 0.276 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr6_-_24719286 0.274 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr16_-_4897265 0.273 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr10_+_81107219 0.273 NM_005729
PPIF
peptidylprolyl isomerase F
chr5_+_34687663 0.272 NM_001145523
RAI14
retinoic acid induced 14
chr5_-_88179278 0.268 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr4_+_186064416 0.266 NM_001151
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr1_+_23037329 0.265 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr10_-_101492422 0.265 NM_004376
NM_078470
COX15

COX15 homolog, cytochrome c oxidase assembly protein (yeast)

chr2_-_47142950 0.262 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr20_-_23066828 0.261 NM_012072
CD93
CD93 molecule
chr10_+_89623091 0.260 NM_000314
PTEN
phosphatase and tensin homolog
chr18_+_9913954 0.259 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr6_-_35696359 0.257 NM_001145775
FKBP5
FK506 binding protein 5
chr16_+_58497548 0.257 NM_020465
NDRG4
NDRG family member 4
chr2_-_47143250 0.256 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chr2_+_88991166 0.255 NM_144563
RPIA
ribose 5-phosphate isomerase A
chr17_-_10372875 0.251 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr16_+_15068832 0.251 NM_015027
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr12_+_32654976 0.250 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_167189948 0.245 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr9_-_94124194 0.244 NM_001698
AUH
AU RNA binding protein/enoyl-CoA hydratase
chr6_+_151646634 0.242 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr4_+_140222668 0.237 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_+_65730423 0.237 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_65241305 0.236 NM_014877
HELZ
helicase with zinc finger
chr16_+_58497993 0.236 NM_001130487
NDRG4
NDRG family member 4
chr11_+_86748870 0.236 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr7_-_14029641 0.232 NM_001163147
NM_004956
ETV1

ets variant 1

chr10_-_65028825 0.231 NM_004241
JMJD1C
jumonji domain containing 1C
chr2_-_225450105 0.229 NM_003590
CUL3
cullin 3
chrX_+_122993536 0.227 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr17_+_58677489 0.222 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr7_-_139876718 0.222 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_-_52587851 0.221 NM_018728
MYO5C
myosin VC
chr11_-_47545539 0.219 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr1_-_247335251 0.213 NM_001243740
NM_003431
ZNF124

zinc finger protein 124

chr16_-_58231641 0.212 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr2_-_47168902 0.209 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr20_+_37434294 0.207 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr12_+_72233486 0.206 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr3_-_50365663 0.205 NM_007275
TUSC2
tumor suppressor candidate 2
chr10_+_30722856 0.202 NM_001244134
NM_005204
MAP3K8

mitogen-activated protein kinase kinase kinase 8

chr8_-_60031545 0.202 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr1_-_231560789 0.200 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr14_+_103058988 0.200 NM_015156
RCOR1
REST corepressor 1
chr10_+_11206928 0.198 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr5_+_127419407 0.198 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr5_+_72143929 0.198 NM_153188
TNPO1
transportin 1
chr1_-_51984994 0.196 NM_001981
EPS15
epidermal growth factor receptor pathway substrate 15
chr13_+_20532788 0.195 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr4_+_1873035 0.195 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr7_+_117824085 0.194 NM_016200
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr13_+_20532906 0.192 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr18_-_55253785 0.192 NM_000140
NM_001012515
FECH

ferrochelatase

chr10_-_65225605 0.191 NM_032776
JMJD1C
jumonji domain containing 1C
chr1_+_24286300 0.188 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr5_+_56110899 0.188 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr1_-_150669499 0.187 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr19_-_48744276 0.186 NM_001184900
CARD8
caspase recruitment domain family, member 8
chr17_-_38574042 0.183 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr19_-_48752921 0.182 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr1_-_55681024 0.178 NM_015306
USP24
ubiquitin specific peptidase 24
chr2_-_21022812 0.172 NM_021925
C2orf43
chromosome 2 open reading frame 43
chr2_-_172017358 0.168 NM_012290
TLK1
tousled-like kinase 1
chr12_+_81471796 0.166 NM_024560
ACSS3
acyl-CoA synthetase short-chain family member 3
chr4_-_76439582 0.166 NM_001008925
NM_001009922
NM_015436
RCHY1


ring finger and CHY zinc finger domain containing 1


chrX_+_64708614 0.166 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr3_-_66550844 0.165 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr8_-_8750739 0.165 NM_004225
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr8_+_61591239 0.164 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr11_+_75526211 0.164 NM_003369
UVRAG
UV radiation resistance associated gene
chr1_-_68962726 0.162 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr2_-_37193609 0.161 NM_003162
STRN
striatin, calmodulin binding protein
chr2_+_152214105 0.161 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr3_+_38495778 0.160 NM_001106
ACVR2B
activin A receptor, type IIB
chr12_+_74931550 0.160 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr10_+_99079017 0.158 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr1_+_159141376 0.157 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr16_+_31885077 0.157 NM_003414
ZNF267
zinc finger protein 267
chr12_+_12938540 0.157 NM_030817
APOLD1
apolipoprotein L domain containing 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
22.47 7.69e-03 GO:0003690 double-stranded DNA binding
16.50 1.91e-02 GO:0043566 structure-specific DNA binding
5.96 2.37e-02 GO:0001071 nucleic acid binding transcription factor activity
5.96 2.37e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
43.09 2.75e-02 GO:0008301 DNA bending activity
37.71 3.59e-02 GO:0035258 steroid hormone receptor binding