Motif ID: AAUCUCA

Z-value: 0.361


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_50697319 0.405 NM_002126
HLF
hepatic leukemia factor
chr20_-_21326046 0.313 NM_033176
NKX2-4
NK2 homeobox 4
chr5_-_59225377 0.236 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_48630790 0.220 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr3_-_48675321 0.213 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr1_+_175407153 0.206 NM_021165
FAM5B
family with sequence similarity 5, member B
chrX_+_23262905 0.193 NM_173495
PTCHD1
patched domain containing 1
chr2_-_158162271 0.184 NM_001111031
ACVR1C
activin A receptor, type IC
chr6_-_94185780 0.169 NM_004440
EPHA7
EPH receptor A7
chr11_+_111353218 0.165 NM_033425
DIXDC1
DIX domain containing 1
chr5_+_68823874 0.160 NM_002538
OCLN
occludin
chr4_-_90978469 0.159 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_66218247 0.159 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr4_+_82171142 0.152 NM_001201
BMP3
bone morphogenetic protein 3
chr3_+_143824955 0.147 NM_002670
PLS1
plastin 1
chr10_-_128884411 0.142 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr14_-_79747592 0.138 NM_001007023
DIO2
deiodinase, iodothyronine, type II
chr21_+_34963557 0.137 NM_053277
CLIC6
chloride intracellular channel 6
chr10_+_11099860 0.133 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr8_-_114518194 0.133 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr1_-_205272619 0.126 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr3_+_19164973 0.124 NM_144633
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr10_-_97190885 0.120 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr11_-_16992524 0.120 NM_175058
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr4_+_155884600 0.118 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr5_-_148422799 0.117 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr12_+_4889309 0.117 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr17_+_29621352 0.115 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr18_+_13208777 0.112 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr5_+_149131695 0.110 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr5_-_59100194 0.110 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr13_+_95541093 0.110 NM_153456
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr5_-_58688428 0.109 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58918031 0.109 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_90977149 0.106 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr1_+_24755152 0.105 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr17_+_14145051 0.104 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chrX_+_144707022 0.102 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chrX_-_111212659 0.100 NM_012471
TRPC5
transient receptor potential cation channel, subfamily C, member 5
chr2_-_172675480 0.098 NM_004405
DLX2
distal-less homeobox 2
chr3_-_42892636 0.097 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr15_+_38520594 0.096 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr1_-_202595666 0.096 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_-_194844061 0.094 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chrX_-_118168569 0.091 NM_020721
KIAA1210
KIAA1210
chr22_-_45311730 0.090 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr7_-_139523187 0.090 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr10_-_116408046 0.089 NM_002313
ABLIM1
actin binding LIM protein 1
chr18_+_13601664 0.087 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr8_+_1909437 0.086 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr1_-_159257595 0.084 NM_016946
F11R
F11 receptor
chr15_+_89444185 0.083 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr3_+_143858428 0.083 NM_001172312
PLS1
plastin 1
chr1_-_68688219 0.081 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chrX_-_109570113 0.080 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chrX_-_20194629 0.079 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_+_39826032 0.078 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr11_+_124294355 0.077 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr4_+_155921876 0.076 NM_144979
RBM46
RNA binding motif protein 46
chr18_+_53170718 0.075 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_-_132318080 0.075 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr1_+_78729315 0.074 NM_000959
NM_001039585
PTGFR

prostaglandin F receptor (FP)

chr5_-_58370693 0.073 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr2_+_234490781 0.072 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr9_-_36266930 0.072 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr1_+_179719338 0.072 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr15_+_89444433 0.072 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr5_-_54558899 0.072 NM_001190787
LOC345643
hypothetical LOC345643
chr6_+_97479216 0.071 NM_052904
KLHL32
kelch-like 32 (Drosophila)
chr3_+_45902999 0.068 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr10_-_97311084 0.066 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chrX_-_10548458 0.066 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr7_-_105106844 0.065 NM_138495
ATXN7L1
ataxin 7-like 1
chr16_+_8722068 0.065 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr12_+_105602606 0.062 NM_032491
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chrX_-_30817329 0.062 NM_152787
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr4_-_86106567 0.062 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr16_-_10184111 0.062 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr14_-_79748273 0.061 NM_000793
NM_013989
DIO2

deiodinase, iodothyronine, type II

chr9_+_4652285 0.061 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr14_+_103464504 0.060 NM_153046
TDRD9
tudor domain containing 9
chr5_-_58607673 0.060 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_81744469 0.060 NM_001717
BNC1
basonuclin 1
chr2_+_108604111 0.060 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr8_-_87590097 0.060 NM_016033
FAM82B
family with sequence similarity 82, member B
chr9_+_86474393 0.057 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr8_+_17398940 0.057 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chrX_+_144710557 0.057 NM_001144006
NM_001144008
NM_001144009
NM_001144010
SLITRK2



SLIT and NTRK-like family, member 2



chr22_-_22633317 0.057 NM_000854
NM_001080843
GSTT2
GSTT2B
glutathione S-transferase theta 2
glutathione S-transferase theta 2B (gene/pseudogene)
chr12_-_24947233 0.055 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_+_105501161 0.055 NM_213594
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr15_-_75364387 0.053 NM_024776
PEAK1
NKF3 kinase family member
chr6_-_82519093 0.053 NM_017633
FAM46A
family with sequence similarity 46, member A
chr2_-_158193639 0.052 NM_001111032
NM_001111033
NM_145259
ACVR1C


activin A receptor, type IC


chrX_-_10605726 0.052 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr10_+_112394094 0.052 NM_001134363
RBM20
RNA binding motif protein 20
chr10_+_11087259 0.051 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr5_+_40715778 0.051 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr8_-_89408832 0.051 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr13_-_99422163 0.051 NM_033132
ZIC5
Zic family member 5 (odd-paired homolog, Drosophila)
chr16_-_10819957 0.050 NM_001079512
FAM18A
family with sequence similarity 18, member A
chr5_-_34078991 0.050 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr15_-_41449399 0.050 NM_152455
ZSCAN29
zinc finger and SCAN domain containing 29
chr12_-_24946495 0.050 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr10_+_42597959 0.049 NM_014753
BMS1
BMS1 homolog, ribosome assembly protein (yeast)
chr2_-_37397669 0.049 NM_005813
PRKD3
protein kinase D3
chr15_+_63701322 0.048 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr8_+_17440664 0.048 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr16_+_66236512 0.048 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chrX_-_10761729 0.048 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr12_-_48523123 0.047 NM_181708
BCDIN3D
BCDIN3 domain containing
chr1_-_67292616 0.047 NM_015139
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr12_-_10142779 0.047 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr3_+_128190070 0.046 NM_032242
PLXNA1
plexin A1
chr3_-_74652952 0.045 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr16_-_56077827 0.044 NM_018110
DOK4
docking protein 4
chr3_+_191588354 0.044 NM_006580
CLDN16
claudin 16
chr17_+_45401560 0.044 NM_138281
DLX4
distal-less homeobox 4
chr19_-_42098758 0.044 NM_001171979
ZNF829
zinc finger protein 829
chr15_-_32875040 0.043 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr17_+_6867090 0.042 NM_181844
BCL6B
B-cell CLL/lymphoma 6, member B
chr14_-_103383483 0.042 NM_015316
PPP1R13B
protein phosphatase 1, regulatory (inhibitor) subunit 13B
chr17_+_56831951 0.042 NM_005994
TBX2
T-box 2
chr12_+_10054492 0.040 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chr18_-_21186107 0.040 NM_015461
ZNF521
zinc finger protein 521
chr9_+_17124974 0.039 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr21_+_34658192 0.039 NM_172201
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr2_-_228754585 0.039 NM_001142644
NM_030623
SPHKAP

SPHK1 interactor, AKAP domain containing

chr8_-_57395794 0.038 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr13_-_20374895 0.038 NM_022459
XPO4
exportin 4
chr17_-_7328237 0.038 NM_020899
ZBTB4
zinc finger and BTB domain containing 4
chr3_-_178397706 0.038 NM_024665
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr9_-_14769530 0.038 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr18_-_22696532 0.037 NM_004028
AQP4
aquaporin 4
chr15_-_40287773 0.037 NM_015289
VPS39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr2_+_108590032 0.036 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_+_58715988 0.036 NM_018555
ZNF331
zinc finger protein 331
chr4_-_141568210 0.035 NM_001130675
NM_004362
CLGN

calmegin

chrX_+_104953187 0.035 NM_198465
NRK
Nik related kinase
chr9_-_21021566 0.033 NM_001010915
PTPLAD2
protein tyrosine phosphatase-like A domain containing 2
chrX_+_103297891 0.033 NM_207318
FAM199X
family with sequence similarity 199, X-linked
chr4_+_53938567 0.033 NM_001134937
NM_001134938
NM_030917
FIP1L1


FIP1 like 1 (S. cerevisiae)


chr19_-_11477689 0.033 NM_138783
ZNF653
zinc finger protein 653
chr9_-_103540682 0.033 NM_133445
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr3_+_85090721 0.033 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr4_+_145786622 0.032 NM_022475
HHIP
hedgehog interacting protein
chrX_-_10504852 0.032 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr1_-_52228880 0.032 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr9_-_14683459 0.032 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr2_+_177965617 0.032 NM_003659
AGPS
alkylglycerone phosphate synthase
chr11_+_111450177 0.031 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr11_+_91724909 0.030 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr4_-_120445047 0.030 NM_001170330
C4orf3
chromosome 4 open reading frame 3
chr1_+_234748187 0.030 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr18_+_13610866 0.029 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr3_-_153541468 0.029 NM_001123228
TMEM14E
transmembrane protein 14E
chr7_-_139123906 0.029 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr7_-_113346284 0.029 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr3_+_197780105 0.029 NM_001105573
FBXO45
F-box protein 45
chr3_+_173954940 0.029 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr9_+_114552871 0.028 NM_001012994
SNX30
sorting nexin family member 30
chr4_-_9727598 0.028 NM_005112
NM_017491
WDR1

WD repeat domain 1

chr16_-_4232053 0.027 NM_001098814
SRL
sarcalumenin
chr12_+_11693993 0.026 NM_001987
ETV6
ets variant 6
chr19_-_42098919 0.025 NM_001037232
ZNF829
zinc finger protein 829
chr21_+_37713076 0.025 NM_130436
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr11_-_129689669 0.025 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr6_-_40003295 0.024 NM_005943
MOCS1
molybdenum cofactor synthesis 1
chr14_+_72672893 0.024 NM_000021
NM_007318
PSEN1

presenilin 1

chrX_-_19598912 0.023 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_152422322 0.023 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chrX_+_119622570 0.023 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr19_+_49838930 0.023 NM_001135768
NM_001135769
NM_001135770
NM_006505
PVR



poliovirus receptor



chr12_+_132167057 0.022 NM_003440
ZNF140
zinc finger protein 140
chr6_+_31059463 0.022 NM_001010909
MUC21
mucin 21, cell surface associated
chr5_+_138920893 0.021 NM_003339
NM_181838
UBE2D2

ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)

chr18_-_65775139 0.020 NM_006566
CD226
CD226 molecule
chr3_+_171560104 0.020 NM_001145097
SKIL
SKI-like oncogene
chr11_-_128567302 0.019 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr1_+_234753361 0.019 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr19_+_58733144 0.019 NM_001079906
ZNF331
zinc finger protein 331
chr22_+_22652248 0.019 NM_000854
GSTT2
GSTT2B
glutathione S-transferase theta 2
glutathione S-transferase theta 2B (gene/pseudogene)
chr2_+_111594921 0.018 NM_006538
NM_138621
NM_207002
BCL2L11


BCL2-like 11 (apoptosis facilitator)


chr1_+_101134177 0.018 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chrX_-_7855400 0.017 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr19_+_58750305 0.017 NM_001079907
ZNF331
zinc finger protein 331
chr7_+_134114701 0.017 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr2_+_174968701 0.016 NM_001193528
NM_024583
SCRN3

secernin 3

chr19_+_57592913 0.016 NM_032423
ZNF528
zinc finger protein 528
chr19_-_60566419 0.016 NM_001145402
FAM71E2
family with sequence similarity 71, member E2
chr1_+_176329452 0.016 NM_170692
RASAL2
RAS protein activator like 2
chrX_+_119621771 0.016 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr12_-_2856560 0.016 NM_021953
NM_202002
NM_202003
FOXM1


forkhead box M1


chr1_-_67668686 0.016 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr16_+_31098931 0.016 NM_001170634
NM_001170937
NM_004960
FUS


fused in sarcoma


chrX_-_109447970 0.015 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr6_-_40010118 0.015 NM_001075098
MOCS1
molybdenum cofactor synthesis 1
chr3_-_161584137 0.015 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr10_-_116276651 0.015 NM_006720
ABLIM1
actin binding LIM protein 1
chr21_+_37661728 0.015 NM_101395
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.