Motif ID: ATF5_CREB3.p2

Z-value: 2.150


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3



Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_156897286 4.603 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_+_101462375 3.200 NM_018309
TBC1D23
TBC1 domain family, member 23
chr6_+_89848229 2.988 PNRC1
proline-rich nuclear receptor coactivator 1
chr2_+_177785667 2.578 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr2_+_219453487 2.570 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr2_+_206847658 2.510 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr3_-_120665113 2.463 NM_018266
TMEM39A
transmembrane protein 39A
chr14_-_35348086 2.377 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr22_+_40286957 2.334 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr4_-_170770111 2.320 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr2_+_105320440 2.273 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr18_+_29412538 2.243 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr14_-_35859545 2.100 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr16_+_68938264 2.069 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr2_+_105320247 2.034 C2orf49
chromosome 2 open reading frame 49
chr17_-_55958274 1.988 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr20_+_32755778 1.986 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr3_-_122951200 1.964 NM_004487
GOLGB1
golgin B1
chr16_-_66072477 1.942 NM_004691
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr6_+_26312758 1.859 NM_003545
HIST1H4E
histone cluster 1, H4e
chr6_+_126702914 1.843 NM_001012507
CENPW
centromere protein W
chr17_-_55958073 1.819 APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr14_+_31100330 1.780 NM_025152
NUBPL
nucleotide binding protein-like
chr1_+_169721260 1.765 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr6_+_30693464 1.745 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr20_+_21634293 1.679 NM_006192
PAX1
paired box 1
chr3_-_192063158 1.676 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr3_-_53900888 1.671 NM_021237
SELK
selenoprotein K
chr14_-_38971049 1.660 FBXO33
F-box protein 33
chr11_+_66952462 1.657 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr20_-_38751289 1.657 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr8_+_128875902 1.655 PVT1
Pvt1 oncogene (non-protein coding)
chr20_+_18436167 1.626 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr16_+_18986721 1.623 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr19_-_52308848 1.620 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr6_+_34964999 1.620 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr1_-_19409328 1.619 NM_020765
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr10_-_115923874 1.603 C10orf118
chromosome 10 open reading frame 118
chr12_+_120635021 1.589 NM_001080825
TMEM120B
transmembrane protein 120B
chr4_+_158216631 1.554 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr14_+_34521945 1.546 SRP54
signal recognition particle 54kDa
chr14_+_34585098 1.543 NM_173607
FAM177A1
family with sequence similarity 177, member A1
chr20_+_29656744 1.531 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr14_-_49122813 1.526 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr20_+_5839973 1.515 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr4_+_48527798 1.503 NM_001079840
NM_001079841
NM_017830
NM_001079839
NM_001079842
NM_001168254
OCIAD1





OCIA domain containing 1





chr2_-_180580024 1.494 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr16_+_18986459 1.488 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr17_-_35337288 1.480 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr14_+_23905984 1.472 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr20_-_48163071 1.468 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr14_-_38971370 1.466 NM_203301
FBXO33
F-box protein 33
chr17_-_44058612 1.447 NM_024017
HOXB9
homeobox B9
chr2_-_202353898 1.434 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr14_+_34521854 1.426 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr14_-_35347791 1.419 RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr20_-_2592777 1.415 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr10_+_112247614 1.401 NM_004419
DUSP5
dual specificity phosphatase 5
chr16_+_70437394 1.398 NM_001137675
ATXN1L
ataxin 1-like
chr20_-_5539487 1.393 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr18_-_29412148 1.365


chr2_-_234317362 1.357 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr2_+_62787534 1.353 NM_001142614
EHBP1
EH domain binding protein 1
chr11_-_2149591 1.353 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr20_+_36534871 1.349 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr2_+_96790298 1.339 NM_020184
CNNM4
cyclin M4
chr4_-_23500706 1.333 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr10_+_118990573 1.331 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr20_-_44034346 1.325 ZNF335
zinc finger protein 335
chr22_-_42589543 1.304 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr14_-_38642029 1.302 SEC23A
Sec23 homolog A (S. cerevisiae)
chr4_+_106287391 1.296 NM_001127208
NM_017628
TET2

tet oncogene family member 2

chr6_-_116681863 1.294 NM_021648
TSPYL4
TSPY-like 4
chr13_+_48720047 1.269 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr11_-_66367279 1.259


chr4_-_187884721 1.258


chr9_+_101623957 1.234 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr2_+_10969513 1.218 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr5_-_95323180 1.216 ELL2
elongation factor, RNA polymerase II, 2
chr5_+_50714996 1.209 ISL1
ISL LIM homeobox 1
chr16_-_3707450 1.203 NM_016292
TRAP1
TNF receptor-associated protein 1
chr14_-_38642165 1.198 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr14_-_22127954 1.188 NM_001344
DAD1
defender against cell death 1
chr2_-_54051290 1.185 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr14_-_22891865 1.184 NM_016609
SLC22A17
solute carrier family 22, member 17
chr2_+_219779737 1.184 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr14_-_22127902 1.179 DAD1
defender against cell death 1
chr10_-_90957028 1.173 NM_003956
CH25H
cholesterol 25-hydroxylase
chr3_-_101077605 1.163 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr11_-_76862197 1.154 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr5_-_50714836 1.151 LOC642366
hypothetical LOC642366
chr20_+_51023159 1.149 TSHZ2
teashirt zinc finger homeobox 2
chr11_+_66367458 1.142 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr3_+_186786655 1.133 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr20_+_30161173 1.131 TM9SF4
transmembrane 9 superfamily protein member 4
chr2_-_156894927 1.128 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr5_+_50714714 1.127 NM_002202
ISL1
ISL LIM homeobox 1
chr11_-_124871258 1.122 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr20_+_30160952 1.110 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr9_+_17568952 1.107 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr2_-_97646758 1.104 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr9_-_26882713 1.098 NM_001167575
NM_024828
C9orf82

chromosome 9 open reading frame 82

chr14_+_38714111 1.094 NM_002687
PNN
pinin, desmosome associated protein
chr16_+_18986417 1.093 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr17_-_632135 1.089 NM_016080
GLOD4
glyoxalase domain containing 4
chr2_+_190014432 1.087 WDR75
WD repeat domain 75
chr2_+_108432097 1.087 GCC2
GRIP and coiled-coil domain containing 2
chr9_-_68552337 1.086 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr2_-_202811459 1.079 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr20_-_44034194 1.078 NM_022095
ZNF335
zinc finger protein 335
chr20_+_18436525 1.077 SEC23B
Sec23 homolog B (S. cerevisiae)
chr2_+_108769572 1.072 NM_144978
CCDC138
coiled-coil domain containing 138
chr1_+_78243181 1.071 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_+_64339869 1.064 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_16281287 1.059 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr19_+_4353658 1.048 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr20_-_34835546 1.045 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr6_+_10803141 1.035 NM_017906
PAK1IP1
PAK1 interacting protein 1
chr6_+_56927882 1.017 BEND6
BEN domain containing 6
chr17_+_25828546 1.012 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr9_-_168913 1.011 NM_001145355
NM_001145356
NM_018491
CBWD2
CBWD1


COBW domain containing 2
COBW domain containing 1


chr20_+_36810510 1.010 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr14_+_37748031 1.005 SSTR1
somatostatin receptor 1
chr2_-_60634271 0.999 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr9_-_32540818 0.997 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr2_-_202353818 0.995


chr2_+_8739563 0.991 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr6_-_3102690 0.990 NM_001069
TUBB2A
tubulin, beta 2A
chr15_+_48503860 0.988 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr2_+_183289205 0.987 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_-_133332173 0.983 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr8_+_64243741 0.983 YTHDF3
YTH domain family, member 3
chr17_+_33761234 0.982 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr2_-_25047988 0.981 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr5_-_72780107 0.981 NM_004472
FOXD1
forkhead box D1
chr7_-_19715127 0.979 NM_001002926
TWISTNB
TWIST neighbor
chr6_+_14033076 0.975 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr6_-_128883125 0.973 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr6_+_26705110 0.972 NM_013375
ABT1
activator of basal transcription 1
chr2_+_30307900 0.967 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr12_+_61147083 0.967 MON2
MON2 homolog (S. cerevisiae)
chr3_+_114733907 0.962 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr17_+_632262 0.958 NM_018146
RNMTL1
RNA methyltransferase like 1
chr2_+_190014403 0.957 NM_032168
WDR75
WD repeat domain 75
chr10_+_103901922 0.954 NM_004741
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr6_-_53321658 0.953 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr2_+_95432150 0.953 NM_016044
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr18_-_39111243 0.952 NM_020783
SYT4
synaptotagmin IV
chr5_+_61744322 0.945 NM_016338
IPO11
importin 11
chr6_-_53321545 0.939 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr2_+_33025872 0.937 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr17_+_24095135 0.937 NM_004295
TRAF4
TNF receptor-associated factor 4
chr2_-_97646970 0.936 NM_005735
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr4_-_56948345 0.931 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr2_-_213111525 0.928 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr14_-_23781607 0.928 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr14_+_73423260 0.923 NM_021188
ZNF410
zinc finger protein 410
chr1_-_58938323 0.917 NM_001085487
MYSM1
Myb-like, SWIRM and MPN domains 1
chr12_+_105692466 0.916 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr9_+_115023684 0.916 SLC31A1
solute carrier family 31 (copper transporters), member 1
chr4_-_186584031 0.914 NM_018359
UFSP2
UFM1-specific peptidase 2
chr9_-_101621964 0.905


chr9_+_4669557 0.904 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr2_-_43676603 0.900 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr2_+_170149348 0.897 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr9_-_72218098 0.895 KLF9
Kruppel-like factor 9
chr4_+_72271218 0.892 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr9_+_124066973 0.887 MRRF
mitochondrial ribosome recycling factor
chr6_+_30137014 0.887 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr14_+_103165244 0.883 NM_001130107
NM_005552
NM_182923
KLC1


kinesin light chain 1


chr20_-_39379533 0.880 ZHX3
zinc fingers and homeoboxes 3
chr4_-_120595218 0.877


chr7_-_25131386 0.877 CYCS
cytochrome c, somatic
chr2_-_10747438 0.876 NOL10
nucleolar protein 10
chr15_+_32304477 0.874 NM_016454
TMEM85
transmembrane protein 85
chr6_+_106653429 0.874 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr2_-_10747553 0.871 NM_024894
NOL10
nucleolar protein 10
chr15_+_36533595 0.863 NM_001042429
NM_173611
FAM98B

family with sequence similarity 98, member B

chr13_+_21143083 0.861 NM_002010
FGF9
fibroblast growth factor 9 (glia-activating factor)
chr2_+_113911737 0.859 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr13_-_79810972 0.852 SPRY2
sprouty homolog 2 (Drosophila)
chr17_+_632356 0.852 RNMTL1
RNA methyltransferase like 1
chr12_-_62902279 0.849 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr12_+_58276114 0.847 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr17_+_44263370 0.846 NM_005831
CALCOCO2
calcium binding and coiled-coil domain 2
chr6_+_1336077 0.840


chr6_+_116798791 0.840 NM_013352
DSE
dermatan sulfate epimerase
chr2_-_128000315 0.839 NM_017969
IWS1
IWS1 homolog (S. cerevisiae)
chr22_+_25209812 0.838 NM_001013694
SRRD
SRR1 domain containing
chr22_-_25209761 0.834 NM_022081
HPS4
Hermansky-Pudlak syndrome 4
chr6_-_10802823 0.834 NM_001145020
C6orf52
chromosome 6 open reading frame 52
chr4_-_56197115 0.833 NM_006681
NMU
neuromedin U
chr6_+_14033402 0.833 NM_001165033
RNF182
ring finger protein 182
chr12_-_10657397 0.831 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr2_-_179051471 0.828 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr5_-_72896964 0.826 ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr18_+_55718171 0.820 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr7_-_25131427 0.816 NM_018947
CYCS
cytochrome c, somatic
chr9_+_115023628 0.811 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr6_-_30136734 0.808 ZNRD1-AS1
ZNRD1 antisense RNA 1 (non-protein coding)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.41 5.21e-03 GO:0043231 intracellular membrane-bounded organelle
1.41 5.44e-03 GO:0043227 membrane-bounded organelle

Nothing significant found in function category.