Motif ID: FOXD3.p2

Z-value: 1.271


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3



Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_150304813 3.806 NM_025217
ULBP2
UL16 binding protein 2
chr20_+_19818209 3.341 NM_018993
RIN2
Ras and Rab interactor 2
chr5_+_40877053 2.687 NM_032587
CARD6
caspase recruitment domain family, member 6
chr4_+_120029426 2.007 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr2_+_37282516 1.954 LOC100505876
hypothetical LOC100505876
chr2_+_95621492 1.864 NM_138800
TRIM43
tripartite motif containing 43
chr18_-_13905534 1.827 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr12_+_27066768 1.769 MED21
mediator complex subunit 21
chr2_-_218739891 1.763 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr16_+_68938264 1.748 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr4_+_167013859 1.735 NM_012464
TLL1
tolloid-like 1
chr12_+_27066749 1.722 NM_004264
MED21
mediator complex subunit 21
chr15_+_56217686 1.688 NM_020980
AQP9
aquaporin 9
chr6_+_132000134 1.463 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_+_218768170 1.427 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr22_+_35290271 1.303


chr10_-_31328426 1.260 NM_001143769
ZNF438
zinc finger protein 438
chr1_+_218768146 1.194 MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_-_12599934 1.190 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr16_+_67235651 1.167 NM_001793
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr1_+_239762179 1.166 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr16_+_8622974 1.159 NM_024109
METTL22
methyltransferase like 22
chr20_+_30160952 1.137 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr13_-_35327798 1.130 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr7_-_92615593 1.126 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr20_+_5679032 1.119 NM_152504
C20orf196
chromosome 20 open reading frame 196
chr6_+_26473376 1.098 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr3_-_171070314 1.084 NM_024727
LRRC31
leucine rich repeat containing 31
chr2_-_192420168 1.084 NM_004657
SDPR
serum deprivation response
chr6_+_46869052 1.053 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr1_+_13784553 1.028 NM_001006624
NM_001006625
PDPN

podoplanin

chr6_+_130381408 1.019 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr3_+_11242666 1.017 NM_001098211
HRH1
histamine receptor H1
chr19_-_23248804 1.014 LOC100132815
hypothetical LOC100132815
chr6_+_121798443 1.003 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr12_+_9925354 1.003 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr16_+_20328355 1.001 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr3_+_108578877 0.990 NM_032600
CCDC54
coiled-coil domain containing 54
chr17_-_36719030 0.986 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr1_+_61697209 0.975 NFIA
nuclear factor I/A
chr1_+_12757570 0.965 NM_001080830
PRAMEF12
PRAME family member 12
chr10_+_71231693 0.962 COL13A1
collagen, type XIII, alpha 1
chr3_-_188946168 0.957 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr13_+_109932934 0.950 COL4A2
collagen, type IV, alpha 2
chr2_-_95514205 0.946 NM_001164464
TRIM43
TRIM43B
tripartite motif containing 43
tripartite motif containing 43B
chr18_+_27281729 0.935 NM_001944
DSG3
desmoglein 3
chr6_+_30238961 0.934 NM_033229
TRIM15
tripartite motif containing 15
chr5_+_92944680 0.931 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr18_+_59405513 0.919 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr20_+_51023159 0.909 TSHZ2
teashirt zinc finger homeobox 2
chr2_-_215998181 0.909 FN1
fibronectin 1
chr17_+_45706786 0.908 NM_153229
TMEM92
transmembrane protein 92
chr19_-_54557450 0.897 NM_003598
TEAD2
TEA domain family member 2
chr17_+_59875623 0.896 NM_001085423
C17orf60
chromosome 17 open reading frame 60
chr18_+_27152049 0.885 NM_001942
DSG1
desmoglein 1
chr10_+_71231649 0.881 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr16_+_26985719 0.866 NM_001145545
C16orf82
chromosome 16 open reading frame 82
chr11_-_107969554 0.865 NM_015065
EXPH5
exophilin 5
chr1_+_162795328 0.861 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr21_-_38792173 0.859 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr6_-_128883125 0.848 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr7_+_6583560 0.833 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr20_+_30161173 0.824 TM9SF4
transmembrane 9 superfamily protein member 4
chr3_-_191321367 0.811 LEPREL1
leprecan-like 1
chr20_-_23014828 0.802 NM_012072
CD93
CD93 molecule
chr20_-_33658823 0.798 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr9_-_87904844 0.791 NM_177937
GOLM1
golgi membrane protein 1
chr9_-_4289915 0.790 GLIS3
GLIS family zinc finger 3
chr15_-_64436045 0.780 NM_017858
TIPIN
TIMELESS interacting protein
chr1_+_162795538 0.766 PBX1
pre-B-cell leukemia homeobox 1
chr5_+_159368690 0.766 TTC1
tetratricopeptide repeat domain 1
chr20_+_4650499 0.760 NM_012409
PRND
prion protein 2 (dublet)
chr7_+_116238309 0.753 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_143786993 0.739 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_148936123 0.735 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr1_-_77457664 0.735 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr18_-_12646730 0.719 NM_001128627
SPIRE1
spire homolog 1 (Drosophila)
chr22_+_44828338 0.712


chr20_-_43410437 0.708 NM_002999
SDC4
syndecan 4
chr13_-_40491491 0.708 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_-_170346760 0.706 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr5_+_108111421 0.698 NM_005246
FER
fer (fps/fes related) tyrosine kinase
chr2_+_66516196 0.696 MEIS1
Meis homeobox 1
chr17_-_53847937 0.694 RNF43
ring finger protein 43
chr13_-_98708549 0.691 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr13_-_85271329 0.690 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr2_+_169631777 0.684 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr14_+_22915772 0.683 NM_001037288
NM_138460
CMTM5

CKLF-like MARVEL transmembrane domain containing 5

chr2_-_211049619 0.683 NM_001136574
NM_006055
NM_001136575
LANCL1


LanC lantibiotic synthetase component C-like 1 (bacterial)


chr11_+_48194937 0.682 NM_001005470
OR4B1
olfactory receptor, family 4, subfamily B, member 1
chr17_+_64922420 0.671 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_195336625 0.664 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr14_+_30098079 0.663 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr6_-_136889302 0.658 MAP7
microtubule-associated protein 7
chr2_-_112729072 0.652 NM_032494
ZC3H8
zinc finger CCCH-type containing 8
chr12_-_28016182 0.641 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr1_-_166373434 0.640 GPR161
G protein-coupled receptor 161
chr6_+_31190505 0.639 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr3_+_110338250 0.637 FLJ22763
hypothetical LOC401081
chr8_-_122722674 0.635 NM_005328
HAS2
hyaluronan synthase 2
chr1_-_56817568 0.633 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_10173947 0.632 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr14_-_22722658 0.631 SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr2_+_12775336 0.631 TRIB2
tribbles homolog 2 (Drosophila)
chr11_+_63060848 0.627 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr1_+_84536636 0.625 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr3_+_137224266 0.624 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr10_-_95231933 0.622 NM_013451
NM_133337
MYOF

myoferlin

chr15_-_72981595 0.622 C15orf17
chromosome 15 open reading frame 17
chr5_+_159368721 0.621 TTC1
tetratricopeptide repeat domain 1
chr16_+_65938753 0.619 NM_001161575
LRRC36
leucine rich repeat containing 36
chr14_+_31868229 0.616 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr9_+_71134060 0.616 NM_004816
FAM189A2
family with sequence similarity 189, member A2
chr3_-_64647325 0.613 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr2_+_61225710 0.613 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr18_-_46068689 0.612 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr7_-_25234582 0.609 NM_022150
NPVF
neuropeptide VF precursor
chr20_+_9146036 0.609 NM_182797
PLCB4
phospholipase C, beta 4
chr14_-_22722680 0.604 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr14_-_31026901 0.602 NM_001197184
GPR33
G protein-coupled receptor 33 (gene/pseudogene)
chr6_-_159386007 0.602 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr22_+_27779877 0.599 ZNRF3
zinc and ring finger 3
chr2_+_39000007 0.599 NM_001145451
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr7_-_135083906 0.598 NM_205855
FAM180A
family with sequence similarity 180, member A
chr13_-_40491405 0.596 ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_134226727 0.594 CALD1
caldesmon 1
chr8_+_23157094 0.593 NM_152272
CHMP7
CHMP family, member 7
chr2_+_108571209 0.588 LIMS1
LIM and senescent cell antigen-like domains 1
chr7_-_112513379 0.585 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr15_-_61460967 0.583 CA12
carbonic anhydrase XII
chr3_-_42818221 0.580


chr17_+_53587492 0.579 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr4_+_128773529 0.579 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr12_-_51065629 0.578 NM_033045
KRT84
keratin 84
chr2_-_133145539 0.574 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr14_+_50096492 0.574 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr10_+_124135574 0.574 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_+_200878848 0.574 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr8_-_108579270 0.571 NM_001146
ANGPT1
angiopoietin 1
chr12_+_121885246 0.569 HIP1R
huntingtin interacting protein 1 related
chr12_+_52708460 0.568 NM_004503
HOXC6
homeobox C6
chr17_+_36515166 0.566 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr19_-_14853166 0.564 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr3_-_11736946 0.564 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr16_+_79829794 0.562 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr1_+_81544432 0.562 LPHN2
latrophilin 2
chr2_+_169634330 0.559 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr9_-_14076901 0.559 NFIB
nuclear factor I/B
chr2_+_101874809 0.556 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr15_-_61461127 0.556 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr8_+_12914143 0.555 NM_001099677
KIAA1456
KIAA1456
chr20_+_19863716 0.554 RIN2
Ras and Rab interactor 2
chr4_+_159662349 0.553 NM_021634
RXFP1
relaxin/insulin-like family peptide receptor 1
chr2_+_151922350 0.551 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr16_-_28542366 0.551 NM_177536
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_+_101874765 0.550 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_-_153523113 0.548 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr16_+_24648446 0.540 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr11_+_101488380 0.539 NM_001195045
YAP1
Yes-associated protein 1
chr7_-_83662152 0.535 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_12935222 0.532 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr6_-_167717907 0.531 NM_004610
TCP10
t-complex 10 homolog (mouse)
chr3_-_131948202 0.531 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr3_+_171022403 0.530 NM_001080460
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr9_-_34387786 0.527 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr17_+_4638966 0.517 NM_001014985
GLTPD2
glycolipid transfer protein domain containing 2
chr3_-_150569574 0.517 TM4SF1
transmembrane 4 L six family member 1
chr9_-_4290028 0.513 NM_001042413
GLIS3
GLIS family zinc finger 3
chr3_+_100840129 0.510 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr5_+_159546951 0.509 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr1_-_168310232 0.506 NM_014970
KIFAP3
kinesin-associated protein 3
chr6_-_26358811 0.505 NM_021018
HIST1H3F
histone cluster 1, H3f
chr12_+_97513644 0.503 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr19_-_57223329 0.503 NM_025040
ZNF614
zinc finger protein 614
chr18_-_22699650 0.501 NM_001650
AQP4
aquaporin 4
chr20_-_43163021 0.500 NM_002251
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr2_+_12775814 0.499


chr14_-_34252695 0.497 NM_021914
CFL2
cofilin 2 (muscle)
chr6_+_148705817 0.496 SASH1
SAM and SH3 domain containing 1
chr2_-_27215781 0.495 NM_178553
C2orf53
chromosome 2 open reading frame 53
chr2_-_151052391 0.494 NM_005168
RND3
Rho family GTPase 3
chr3_+_114414064 0.492 NM_033254
BOC
Boc homolog (mouse)
chr15_+_91244563 0.492 CHD2
chromodomain helicase DNA binding protein 2
chr7_-_27186400 0.489 NM_153715
HOXA10
homeobox A10
chr9_-_116608113 0.488 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr14_-_105681377 0.488 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_-_126839000 0.488 CTBP2
C-terminal binding protein 2
chr1_-_56817717 0.487 PPAP2B
phosphatidic acid phosphatase type 2B
chr20_+_54533191 0.486 NM_001012971
C20orf106
C20orf107
chromosome 20 open reading frame 106
chromosome 20 open reading frame 107
chr16_+_29942155 0.485 NM_001109659
NM_001109660
C16orf92

chromosome 16 open reading frame 92

chr17_-_39094787 0.481 NM_001040002
MEOX1
mesenchyme homeobox 1
chr4_+_75449720 0.481 NM_001432
EREG
epiregulin
chr15_+_91244422 0.480 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr1_+_76312962 0.478 NM_001160011
NM_152996
ST6GALNAC3

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

chr6_+_167504070 0.477 NM_001145121
TCP10L2
TCP10
t-complex 10-like 2 (mouse)
t-complex 10 homolog (mouse)
chr1_+_21639146 0.477 NM_032264
NBPF3
neuroblastoma breakpoint family, member 3
chr5_-_111119846 0.477 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr3_-_127810087 0.476 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr12_+_63090008 0.474 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr20_+_56919233 0.474 GNAS
GNAS complex locus

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.30 1.40e-02 GO:0031226 intrinsic to plasma membrane
3.12 2.75e-02 GO:0044459 plasma membrane part

Nothing significant found in function category.