Motif ID: FOXO1,3,4.p2

Z-value: 1.428


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4



Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_120155581 2.172 NM_001159352
NM_001159353
NM_032044
REG4


regenerating islet-derived family, member 4


chr5_+_66160359 1.581 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_+_60962318 1.296 NM_001145014
RFPL4A
ret finger protein-like 4A
chr4_+_88973144 1.283 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr8_+_12847521 1.268 NM_020844
KIAA1456
KIAA1456
chr7_-_107558021 1.210 NM_007356
LAMB4
laminin, beta 4
chr1_+_162795538 1.127 PBX1
pre-B-cell leukemia homeobox 1
chr1_-_7895873 1.118 UTS2
urotensin 2
chr2_-_200033445 1.086 SATB2
SATB homeobox 2
chr6_+_131498540 1.054 AKAP7
A kinase (PRKA) anchor protein 7
chr6_-_159386007 1.050 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr11_-_117305277 1.043 NM_001077263
TMPRSS13
transmembrane protease, serine 13
chr8_+_79740813 1.034 NM_016010
FAM164A
family with sequence similarity 164, member A
chr8_+_19215279 1.019 NM_001174160
NM_022071
NM_001174159
SH2D4A


SH2 domain containing 4A


chr3_-_150533948 1.004 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr2_+_135312655 0.976 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr5_-_42847716 0.969 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr1_+_153366928 0.951 NM_004428
NM_182685
EFNA1

ephrin-A1

chr17_+_64922420 0.943 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_155731288 0.912 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr17_-_36570508 0.910 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr18_+_45342398 0.896 NM_006033
LIPG
lipase, endothelial
chr6_+_123152044 0.884 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr2_+_113542017 0.872 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr4_+_124540114 0.871 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_-_125956996 0.869 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr14_-_21108714 0.833 NM_001005465
OR10G3
olfactory receptor, family 10, subfamily G, member 3
chr6_+_47732181 0.823 NM_153839
GPR111
G protein-coupled receptor 111
chr7_+_102775309 0.819 NM_002803
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr7_+_37689903 0.818


chr7_+_134483305 0.807 NM_018295
TMEM140
transmembrane protein 140
chr17_-_36559579 0.801 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr3_-_197726587 0.793 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr15_+_41772375 0.791 NM_001015001
CKMT1A
creatine kinase, mitochondrial 1A
chr11_-_5247948 0.780 NM_005330
HBE1
hemoglobin, epsilon 1
chr17_+_59875623 0.779 NM_001085423
C17orf60
chromosome 17 open reading frame 60
chr1_-_166373434 0.779 GPR161
G protein-coupled receptor 161
chr6_-_48186868 0.764 C6orf138
chromosome 6 open reading frame 138
chr3_-_152403636 0.764 NM_013308
GPR171
G protein-coupled receptor 171
chr8_-_110724594 0.759 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr2_-_112729072 0.757 NM_032494
ZC3H8
zinc finger CCCH-type containing 8
chr20_-_19984685 0.744 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr17_-_36577949 0.744 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr2_-_142605739 0.734 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr17_-_51164443 0.733 NM_001099640
TMEM100
transmembrane protein 100
chr3_-_11736946 0.730 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr17_+_23818922 0.729


chr11_-_10630408 0.725 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr12_+_32578513 0.717 FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_64709063 0.710 NM_020925
CACHD1
cache domain containing 1
chr19_+_17972923 0.707 NM_001025604
ARRDC2
arrestin domain containing 2
chr14_+_38653177 0.698 NM_001009182
NM_001009183
NM_003616
SIP1


survival of motor neuron protein interacting protein 1


chr11_-_113971607 0.695 FAM55D
family with sequence similarity 55, member D
chr12_+_50633430 0.690 NM_020327
ACVR1B
activin A receptor, type IB
chr10_+_111975618 0.683 NM_005962
MXI1
MAX interactor 1
chr1_-_24342158 0.683 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr6_+_121798443 0.679 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr3_-_137395966 0.672 NM_001145417
MSL2
male-specific lethal 2 homolog (Drosophila)
chr4_-_186934059 0.670 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr5_+_73145098 0.669 RGNEF
190 kDa guanine nucleotide exchange factor
chr5_+_40877053 0.668 NM_032587
CARD6
caspase recruitment domain family, member 6
chr5_+_36644187 0.650 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_192419896 0.647 SDPR
serum deprivation response
chr15_+_54444907 0.644 NM_198524
TEX9
testis expressed 9
chr11_+_36572615 0.643 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr2_+_158666627 0.639 NM_173355
UPP2
uridine phosphorylase 2
chr19_-_57223329 0.637 NM_025040
ZNF614
zinc finger protein 614
chr9_+_107464558 0.636 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr3_+_133518966 0.627 ACPP
acid phosphatase, prostate
chr7_-_16811131 0.620 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr5_-_58607673 0.616 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_98132898 0.615 NM_001012761
RGMB
RGM domain family, member B
chr11_+_101488380 0.614 NM_001195045
YAP1
Yes-associated protein 1
chr17_-_36403910 0.606 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr4_-_107508040 0.601 NM_001195138
LOC100507096
GTPase IMAP family member-like
chr2_-_17563186 0.601 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr17_-_53847937 0.597 RNF43
ring finger protein 43
chr2_-_180135559 0.589 NM_001113398
ZNF385B
zinc finger protein 385B
chr2_-_99238001 0.582 NM_175735
LYG2
lysozyme G-like 2
chr6_-_28663045 0.578 NM_052923
SCAND3
SCAN domain containing 3
chr14_-_98807574 0.578 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr2_+_65136989 0.577 NM_015147
CEP68
centrosomal protein 68kDa
chr16_+_54070302 0.574 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_+_49604782 0.573 NM_014033
METTL7A
methyltransferase like 7A
chr8_-_20084892 0.571 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr12_+_98565663 0.570 NM_153364
FAM71C
family with sequence similarity 71, member C
chr11_-_102250876 0.570 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr9_+_696744 0.568 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr12_+_49605010 0.564 METTL7A
methyltransferase like 7A
chr14_+_19598043 0.560 NM_001004717
OR4L1
olfactory receptor, family 4, subfamily L, member 1
chr9_-_16717887 0.558 BNC2
basonuclin 2
chr20_+_32567844 0.558 NM_014183
DYNLRB1
dynein, light chain, roadblock-type 1
chr6_+_134800533 0.558 LOC154092
hypothetical LOC154092
chr11_-_113971681 0.556 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr6_+_139136349 0.556 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr2_+_202379442 0.555 NM_139158
CDK15
cyclin-dependent kinase 15
chr18_-_54447168 0.546 NM_052947
ALPK2
alpha-kinase 2
chr9_-_39278061 0.544 NM_033655
LOC441402
CNTNAP3
contactin associated protein-like 3 pseudogene
contactin associated protein-like 3
chr2_-_39310176 0.534 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr14_-_56342097 0.529 NM_172337
OTX2
orthodenticle homeobox 2
chr6_-_52217185 0.528 NM_052872
IL17F
interleukin 17F
chr13_-_98428244 0.527 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr16_+_54072969 0.527 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr4_+_187227302 0.526 NM_003265
TLR3
toll-like receptor 3
chr6_+_64289585 0.524 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_+_218698242 0.521 NM_001168298
CXCR2
chemokine (C-X-C motif) receptor 2
chr4_+_73123712 0.519 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr5_-_10360873 0.519 CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr4_-_140443061 0.518 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr17_+_36642240 0.516 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr1_-_115039614 0.515 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr17_-_34262862 0.514 RPL23
ribosomal protein L23
chr18_-_50776276 0.513 NM_001143829
CCDC68
coiled-coil domain containing 68
chr10_-_61570665 0.503 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_40510923 0.501 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr6_-_130578110 0.497 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr14_+_22911857 0.496 NM_172314
NM_022789
IL25

interleukin 25

chr17_-_36276987 0.489 NM_000223
KRT12
keratin 12
chr21_+_36429079 0.486 NM_001236
CBR3
carbonyl reductase 3
chr2_+_218698980 0.484 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr11_-_85115105 0.482 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr1_-_166373159 0.479 GPR161
G protein-coupled receptor 161
chr3_+_133518900 0.479 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr17_-_64834780 0.478 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr11_-_106833715 0.478 NM_152434
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr3_+_143824955 0.474 NM_002670
PLS1
plastin 1
chr5_-_125958503 0.474 NM_001182
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr18_+_59374372 0.473 NM_080474
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr6_-_29081015 0.473 NM_001010877
ZNF311
zinc finger protein 311
chr4_+_77214886 0.470 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr4_-_152368492 0.470 SH3D19
SH3 domain containing 19
chr1_-_56817568 0.469 PPAP2B
phosphatidic acid phosphatase type 2B
chr14_-_98807307 0.465 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr5_-_43550891 0.462 NM_198566
C5orf34
chromosome 5 open reading frame 34
chr3_+_100840129 0.462 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr18_-_20106187 0.459 NM_018030
OSBPL1A
oxysterol binding protein-like 1A
chr11_-_113935789 0.457 NM_152315
FAM55A
family with sequence similarity 55, member A
chr4_-_82612049 0.457 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chr6_-_46997579 0.456 NM_001098518
GPR116
G protein-coupled receptor 116
chr4_-_139382672 0.456 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr15_+_56217686 0.455 NM_020980
AQP9
aquaporin 9
chr16_+_29697090 0.453 ZG16
zymogen granule protein 16 homolog (rat)
chr7_-_94902149 0.452 NM_000305
NM_001018161
PON2

paraoxonase 2

chr7_+_133982070 0.451 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr6_+_132000134 0.451 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr5_+_34875025 0.449 NM_144725
TTC23L
tetratricopeptide repeat domain 23-like
chr2_+_101974737 0.449 NM_004633
IL1R2
interleukin 1 receptor, type II
chr6_+_30137014 0.448 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr16_+_11966464 0.447 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr5_+_162865128 0.446 NM_013283
MAT2B
methionine adenosyltransferase II, beta
chr1_+_25537372 0.444 NM_014313
TMEM50A
transmembrane protein 50A
chr2_-_218739891 0.442 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr1_-_116185215 0.442 NM_005599
NHLH2
nescient helix loop helix 2
chr1_+_87567136 0.439 LMO4
LIM domain only 4
chr7_+_120752656 0.439 NM_016087
WNT16
wingless-type MMTV integration site family, member 16
chr18_-_59462469 0.438 NM_002974
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr11_-_101828563 0.437 NM_052932
TMEM123
transmembrane protein 123
chr2_-_215605054 0.437 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr17_+_3326045 0.437 NM_000049
ASPA
aspartoacylase
chr2_+_182558795 0.435 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr13_-_38462857 0.435 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr16_+_52027020 0.435 RBL2
retinoblastoma-like 2 (p130)
chr2_-_101134146 0.431 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr7_+_120415958 0.431 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr3_+_188043172 0.430 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr2_-_153282104 0.428 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr20_+_51235228 0.428 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr12_+_21570457 0.424 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr8_-_95634845 0.422 NM_015496
NM_183009
KIAA1429

KIAA1429

chr6_+_111242516 0.421 AMD1
adenosylmethionine decarboxylase 1
chr1_-_56817717 0.418 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_105835525 0.413 COL17A1
collagen, type XVII, alpha 1
chr12_-_7487989 0.410 NM_174941
CD163L1
CD163 molecule-like 1
chr3_+_188043156 0.405 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr7_+_129693938 0.403 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr12_-_9976173 0.403 NM_001130711
CLEC2A
C-type lectin domain family 2, member A
chr3_-_172227461 0.402 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr11_+_129484540 0.402 APLP2
amyloid beta (A4) precursor-like protein 2
chr9_+_66293049 0.402 MGC21881
hypothetical locus MGC21881
chr5_-_59100194 0.397 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_102719732 0.397 NM_032718
MFSD9
major facilitator superfamily domain containing 9
chr20_+_58064360 0.396 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr1_-_148249152 0.396 NM_020205
OTUD7B
OTU domain containing 7B
chr1_-_56817802 0.395 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_152529999 0.392 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr1_-_168310232 0.390 NM_014970
KIFAP3
kinesin-associated protein 3
chr8_-_133841988 0.387 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr16_+_67235651 0.387 NM_001793
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr4_+_146623405 0.387 NM_001003688
SMAD1
SMAD family member 1
chr20_+_62266217 0.386 MYT1
myelin transcription factor 1
chr20_+_42593849 0.386 NM_007066
NM_181804
NM_181805
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr7_-_87774130 0.385 NM_024636
STEAP4
STEAP family member 4
chr14_-_30996348 0.385 NM_080664
C14orf126
HEATR5A
chromosome 14 open reading frame 126
HEAT repeat containing 5A
chr7_+_75892187 0.385 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr1_-_56817823 0.385 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr4_+_75242671 0.384 NM_001144978
MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr6_+_84619703 0.383 NM_001009994
RIPPLY2
ripply2 homolog (zebrafish)
chr1_-_150564302 0.382 NM_002016
FLG
filaggrin
chr17_+_42023353 0.381 NM_006178
NSF
N-ethylmaleimide-sensitive factor
chr12_+_52665196 0.381 NM_017409
HOXC10
homeobox C10

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.