Motif ID: GAGGUAG

Z-value: 1.213


Mature miRNA associated with seed GAGGUAG:

NamemiRBase Accession
hsa-let-7a MIMAT0000062
hsa-let-7b MIMAT0000063
hsa-let-7c MIMAT0000064
hsa-let-7d MIMAT0000065
hsa-let-7e MIMAT0000066
hsa-let-7f MIMAT0000067
hsa-let-7g MIMAT0000414
hsa-let-7i MIMAT0000415
hsa-miR-4458 MIMAT0018980
hsa-miR-4500 MIMAT0019036
hsa-miR-98 MIMAT0000096



Activity profile for motif GAGGUAG.

activity profile for motif GAGGUAG


Sorted Z-values histogram for motif GAGGUAG

Sorted Z-values for motif GAGGUAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GAGGUAG

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_132176921 2.152 NM_175873
ANKRD43
ankyrin repeat domain 43
chr9_+_100745531 2.138 NM_001855
COL15A1
collagen, type XV, alpha 1
chr15_-_63457378 2.014 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr18_+_53253775 2.013 NM_004852
ONECUT2
one cut homeobox 2
chr3_-_171786468 1.979 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr3_+_32834513 1.940 NM_001039111
TRIM71
tripartite motif containing 71
chr8_-_37943143 1.933 NM_000025
ADRB3
adrenergic, beta-3-, receptor
chr2_-_158162271 1.900 NM_001111031
ACVR1C
activin A receptor, type IC
chr19_-_14030970 1.898 NM_001145028
PALM3
paralemmin 3
chr4_-_41849651 1.872 NM_001159547
NM_207406
BEND4

BEN domain containing 4

chr15_-_81113676 1.827 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr17_+_50697319 1.643 NM_002126
HLF
hepatic leukemia factor
chr17_+_44429748 1.638 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr20_+_60918836 1.611 NM_001853
COL9A3
collagen, type IX, alpha 3
chr1_-_163592098 1.568 NM_001174069
LMX1A
LIM homeobox transcription factor 1, alpha
chr16_-_87535106 1.560 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr18_+_13601664 1.557 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr8_+_24828359 1.525 NM_001105541
NEFM
neurofilament, medium polypeptide
chr1_-_163592575 1.507 NM_177398
LMX1A
LIM homeobox transcription factor 1, alpha
chr15_-_43458247 1.458 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_-_45975163 1.434 NM_001080467
MYO5B
myosin VB
chr18_+_13208777 1.434 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr1_+_229365296 1.422 NM_001004342
TRIM67
tripartite motif containing 67
chrX_+_152561086 1.409 NM_001395
DUSP9
dual specificity phosphatase 9
chr1_-_150065176 1.405 NM_001001523
RORC
RAR-related orphan receptor C
chr6_+_111515473 1.342 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr17_-_10042579 1.340 NM_201433
GAS7
growth arrest-specific 7
chr17_+_7283412 1.327 NM_004112
FGF11
fibroblast growth factor 11
chr8_+_24827173 1.319 NM_005382
NEFM
neurofilament, medium polypeptide
chr1_+_41022066 1.315 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr10_+_115793795 1.274 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr15_+_39739864 1.270 NM_001080541
NM_001164273
MGA

MAX gene associated

chr18_+_11741470 1.258 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr5_-_148013908 1.238 NM_000870
HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr3_+_11009419 1.227 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_+_60053050 1.218 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr14_-_100104014 1.213 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chrX_+_2756810 1.213 NM_001079855
NM_001184702
NM_001184703
NM_001184704
NM_003918
GYG2




glycogenin 2




chr1_+_211190476 1.187 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr8_-_109165012 1.164 NM_178565
RSPO2
R-spondin 2 homolog (Xenopus laevis)
chr1_-_200946038 1.163 NM_177402
SYT2
synaptotagmin II
chr6_+_105511615 1.153 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr1_-_227636462 1.152 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chr3_+_185580554 1.137 NM_003741
CHRD
chordin
chr16_-_2186465 1.133 NM_020764
CASKIN1
CASK interacting protein 1
chr22_+_24290738 1.129 NM_005160
ADRBK2
adrenergic, beta, receptor kinase 2
chr15_+_83160914 1.126 NM_020778
ALPK3
alpha-kinase 3
chr12_-_101396459 1.107 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_-_41546384 1.098 NM_001005473
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr16_-_70168449 1.078 NM_000353
TAT
tyrosine aminotransferase
chr2_+_176761552 1.075 NM_024501
HOXD1
homeobox D1
chr17_+_29621352 1.063 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr4_+_2031036 1.046 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chrX_-_99551926 1.036 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr15_-_49418027 1.032 NM_000103
NM_031226
CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

chr21_-_27261276 1.027 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr15_+_55455994 1.025 NM_032866
CGNL1
cingulin-like 1
chr22_+_44925162 1.013 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr13_+_38159172 1.010 NM_207361
FREM2
FRAS1 related extracellular matrix protein 2
chr15_-_75711743 1.010 NM_032808
LINGO1
leucine rich repeat and Ig domain containing 1
chr1_+_26609819 1.001 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr7_+_3307445 1.000 NM_152744
SDK1
sidekick homolog 1, cell adhesion molecule (chicken)
chrX_-_74062005 0.995 NM_001008537
KIAA2022
KIAA2022
chr19_-_52614550 0.991 NM_001009813
NM_020160
MEIS3

Meis homeobox 3

chr5_-_153838013 0.982 NM_004821
HAND1
heart and neural crest derivatives expressed 1
chr6_-_94185780 0.977 NM_004440
EPHA7
EPH receptor A7
chr1_+_179719338 0.976 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr12_+_6292077 0.965 NM_001144857
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr22_+_20101661 0.959 NM_015094
HIC2
hypermethylated in cancer 2
chr15_-_48198697 0.955 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr2_+_11591692 0.953 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr18_+_54013575 0.951 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_-_66511488 0.935 NM_001004439
ITGA11
integrin, alpha 11
chr4_-_174687931 0.929 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chr22_+_48951286 0.928 NM_001160300
NM_052839
PANX2

pannexin 2

chr19_+_1401117 0.927 NM_005883
APC2
adenomatosis polyposis coli 2
chr11_-_129803712 0.915 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr1_-_181654124 0.895 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr3_+_53504070 0.886 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr12_+_70952729 0.857 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr6_-_3390197 0.855 NM_021945
SLC22A23
solute carrier family 22, member 23
chr3_+_49566901 0.853 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr10_+_125415860 0.850 NM_153442
GPR26
G protein-coupled receptor 26
chrX_-_54401161 0.846 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr12_+_56435042 0.846 NM_138396
MARCH9
membrane-associated ring finger (C3HC4) 9
chr3_-_130807865 0.844 NM_015103
PLXND1
plexin D1
chr5_-_35266550 0.844 NM_000949
PRLR
prolactin receptor
chr6_-_90178685 0.842 NM_021244
RRAGD
Ras-related GTP binding D
chr1_-_24386324 0.842 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr12_+_77781903 0.841 NM_001135805
SYT1
synaptotagmin I
chr6_+_87703742 0.840 NM_000865
HTR1E
5-hydroxytryptamine (serotonin) receptor 1E
chr19_-_52667056 0.831 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_-_115682374 0.825 NM_002506
NGF
nerve growth factor (beta polypeptide)
chr19_+_51492136 0.815 NM_152795
HIF3A
hypoxia inducible factor 3, alpha subunit
chr18_+_53967544 0.804 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr5_+_176170041 0.799 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr1_+_29435534 0.780 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr1_-_177378801 0.778 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr9_-_10602722 0.765 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr3_+_103636548 0.762 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr22_+_44083485 0.761 NM_001104595
FAM118A
family with sequence similarity 118, member A
chr9_-_100510657 0.754 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_-_36644122 0.743 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr3_-_53055078 0.739 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr14_-_64508547 0.735 NM_198686
RAB15
RAB15, member RAS onocogene family
chr19_-_7244876 0.731 NM_000208
NM_001079817
INSR

insulin receptor

chr17_-_9803490 0.731 NM_003644
GAS7
growth arrest-specific 7
chr1_-_45444812 0.729 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr1_-_180840016 0.708 NM_002928
RGS16
regulator of G-protein signaling 16
chr5_+_149131695 0.707 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chrX_+_72699686 0.701 NM_001039840
CHIC1
cysteine-rich hydrophobic domain 1
chr11_-_117521344 0.701 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chrX_+_147608302 0.696 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr16_+_49139694 0.692 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr1_-_202647526 0.687 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr13_-_51483473 0.687 NM_000053
NM_001005918
ATP7B

ATPase, Cu++ transporting, beta polypeptide

chr12_-_50502474 0.686 NM_001013690
FIGNL2
fidgetin-like 2
chrX_+_104953187 0.686 NM_198465
NRK
Nik related kinase
chr19_+_5774817 0.685 NM_004558
NRTN
neurturin
chr15_+_49831030 0.681 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr6_+_101953581 0.679 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr21_-_44955889 0.678 NM_144991
TSPEAR
thrombospondin-type laminin G domain and EAR repeats
chr9_-_103540682 0.678 NM_133445
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr12_-_10215942 0.672 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr7_-_23476497 0.672 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr21_-_41801778 0.671 NM_001135099
TMPRSS2
transmembrane protease, serine 2
chr7_+_100584397 0.671 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_+_203804734 0.669 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr7_-_71440143 0.662 NM_001017440
CALN1
calneuron 1
chr17_+_26742767 0.661 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr9_-_76692082 0.658 NM_001177311
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr13_-_32678142 0.655 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_-_200879203 0.644 NM_001136504
SYT2
synaptotagmin II
chr9_+_135314907 0.641 NM_001135775
NM_017586
C9orf7

chromosome 9 open reading frame 7

chr8_-_13018123 0.638 NM_001164271
DLC1
deleted in liver cancer 1
chr5_+_56146656 0.631 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr1_-_86394695 0.630 NM_152890
COL24A1
collagen, type XXIV, alpha 1
chr22_-_37966852 0.628 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr18_+_13610866 0.628 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr11_-_133786935 0.627 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr1_-_40903897 0.626 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr12_+_4253143 0.623 NM_001759
CCND2
cyclin D2
chr19_+_51493486 0.621 NM_022462
HIF3A
hypoxia inducible factor 3, alpha subunit
chrX_-_79951838 0.621 NM_153252
BRWD3
bromodomain and WD repeat domain containing 3
chr12_+_4788602 0.617 NM_002235
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr15_-_27650218 0.616 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr17_+_31082791 0.616 NM_033315
RASL10B
RAS-like, family 10, member B
chr10_+_35575958 0.615 NM_181698
CCNY
cyclin Y
chr22_-_21193504 0.613 NM_080764
ZNF280B
zinc finger protein 280B
chr15_-_63502438 0.611 NM_020962
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr11_+_45825244 0.608 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr3_-_121445831 0.606 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chr7_-_6557591 0.603 NM_001145118
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr7_+_140420500 0.603 NM_001195278
LOC100131199
transmembrane protein 178-like
chr22_-_37970902 0.602 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr15_+_38520594 0.598 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr9_+_4652285 0.596 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr2_-_96899396 0.594 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr22_+_36422940 0.592 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr21_+_26029128 0.590 NM_001197297
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr2_+_204509698 0.587 NM_012092
ICOS
inducible T-cell co-stimulator
chr18_-_43711452 0.584 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr1_+_158636987 0.583 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr5_+_173247919 0.577 NM_030627
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr8_-_22606653 0.576 NM_004430
EGR3
early growth response 3
chr12_+_93066370 0.573 NM_005761
PLXNC1
plexin C1
chr12_-_113330574 0.572 NM_000192
NM_080717
TBX5

T-box 5

chr17_-_7138590 0.564 NM_015982
YBX2
Y box binding protein 2
chr21_-_41801950 0.562 NM_005656
TMPRSS2
transmembrane protease, serine 2
chr10_+_102722275 0.561 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_-_98368913 0.559 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr15_+_40484249 0.558 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr8_-_70909754 0.555 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr16_-_27982277 0.554 NM_001109763
GSG1L
GSG1-like
chr12_-_47735373 0.553 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr4_-_1156959 0.551 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr4_+_76077229 0.551 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr9_+_89302574 0.550 NM_004938
DAPK1
death-associated protein kinase 1
chrX_+_118254233 0.549 NM_006667
PGRMC1
progesterone receptor membrane component 1
chr8_-_17624009 0.541 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr16_+_28211123 0.540 NM_001024401
SBK1
SH3-binding domain kinase 1
chr22_+_38296703 0.539 NM_001003406
NM_021096
CACNA1I

calcium channel, voltage-dependent, T type, alpha 1I subunit

chrX_-_111953009 0.536 NM_001113490
AMOT
angiomotin
chr17_+_8865547 0.535 NM_004822
NTN1
netrin 1
chrX_-_24575375 0.534 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr13_-_32658215 0.531 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_47679176 0.531 NM_015086
DDN
dendrin
chr16_-_2848106 0.528 NM_022119
PRSS22
protease, serine, 22
chr12_-_24946495 0.523 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chrX_-_20194629 0.522 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr11_+_17714070 0.522 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr4_-_171161486 0.521 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr15_+_40481879 0.518 NM_173088
CAPN3
calpain 3, (p94)
chr21_+_36993860 0.516 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr1_+_32417909 0.514 NM_175852
TXLNA
taxilin alpha
chr5_-_131375148 0.508 NM_001009185
NM_015256
ACSL6

acyl-CoA synthetase long-chain family member 6

chr1_-_202387767 0.507 NM_018208
ETNK2
ethanolamine kinase 2
chr14_-_100105883 0.504 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr22_+_22445035 0.503 NM_005940
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chrX_-_15263596 0.501 NM_002641
NM_020473
PIGA

phosphatidylinositol glycan anchor biosynthesis, class A


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.38 9.54e-04 GO:0032502 developmental process
59.75 6.35e-03 GO:0002021 response to dietary excess
199.14 1.35e-02 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
199.14 1.35e-02 GO:0010586 miRNA metabolic process
199.14 1.35e-02 GO:0010587 miRNA catabolic process
21.74 1.35e-02 GO:0040014 regulation of multicellular organism growth
1.91 2.07e-02 GO:0032501 multicellular organismal process
2.33 2.13e-02 GO:0048856 anatomical structure development
2.79 2.39e-02 GO:0030154 cell differentiation
2.23 2.60e-02 GO:0007275 multicellular organismal development
2.71 3.40e-02 GO:0048869 cellular developmental process
33.20 3.97e-02 GO:0045776 negative regulation of blood pressure
119.49 4.46e-02 GO:0002024 diet induced thermogenesis

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
199.14 2.87e-03 GO:0004939 beta-adrenergic receptor activity
149.36 5.73e-03 GO:0051380 norepinephrine binding
99.58 1.43e-02 GO:0051379 epinephrine binding
24.24 2.20e-02 GO:0008227 G-protein coupled amine receptor activity
74.69 2.65e-02 GO:0004935 adrenergic receptor activity
66.39 3.40e-02 GO:0031690 adrenergic receptor binding