Motif ID: NR6A1.p2

Z-value: 0.664


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1



Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_90977149 1.727 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr6_+_84799969 1.298 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr3_-_140879463 0.810 NM_178177
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr2_-_224611568 0.761 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr14_-_106038573 0.611 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr10_-_126097483 0.578 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr19_-_6671585 0.549 NM_000064
C3
complement component 3
chr6_+_32114060 0.539 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr14_-_106038122 0.535 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_-_107969554 0.457 NM_015065
EXPH5
exophilin 5
chr11_+_118259684 0.440 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr2_-_31214868 0.433


chr15_-_38953628 0.414 NM_133639
RHOV
ras homolog gene family, member V
chr7_+_28497272 0.405 CREB5
cAMP responsive element binding protein 5
chr6_+_146906520 0.403 NM_006834
RAB32
RAB32, member RAS oncogene family
chr9_-_21207303 0.398 NM_002173
IFNA16
interferon, alpha 16
chr10_+_106003941 0.394 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr1_+_117253882 0.387 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr12_+_52696908 0.385 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr10_-_126097444 0.379 OAT
ornithine aminotransferase
chr3_+_187866464 0.360 NM_000412
HRG
histidine-rich glycoprotein
chr12_-_56422120 0.357 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_+_65945050 0.354 NM_178864
NPAS4
neuronal PAS domain protein 4
chr7_+_73506172 0.348 GTF2IRD1
GTF2I repeat domain containing 1
chr9_-_14303899 0.344 NFIB
nuclear factor I/B
chr2_-_210798232 0.342 NM_001608
ACADL
acyl-CoA dehydrogenase, long chain
chr9_-_14303943 0.315 NFIB
nuclear factor I/B
chr9_-_14303509 0.305 NFIB
nuclear factor I/B
chr9_-_38059207 0.299 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr9_-_14304036 0.290 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr5_-_14064846 0.289 DNAH5
dynein, axonemal, heavy chain 5
chr10_+_123744131 0.274 TACC2
transforming, acidic coiled-coil containing protein 2
chr6_-_2696152 0.260 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr3_+_46594079 0.260 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr12_+_52697160 0.259 HOXC5
HOXC6
homeobox C5
homeobox C6
chr20_-_29464301 0.255 NM_001171832
DEFB121
defensin, beta 121
chr2_-_31215074 0.254 NM_024572
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr17_-_9870292 0.251 NM_001130831
GAS7
growth arrest-specific 7
chr20_-_42457717 0.245


chr1_+_93072947 0.237 RPL5
ribosomal protein L5
chr7_+_100037817 0.230 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr12_+_107797985 0.228 NM_001917
DAO
D-amino-acid oxidase
chr19_+_46390916 0.220 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr9_-_38059082 0.219 SHB
Src homology 2 domain containing adaptor protein B
chr18_+_8599407 0.218 NM_001025300
RAB12
RAB12, member RAS oncogene family
chr22_-_22252376 0.214 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr11_+_111294868 0.193 C11orf52
chromosome 11 open reading frame 52
chr22_-_22389436 0.177


chr10_+_89409332 0.177 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr8_+_142501188 0.173 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr1_+_113038202 0.167 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr13_+_22653059 0.166 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr7_+_73506047 0.165 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr6_-_132952517 0.164 NM_003967
TAAR5
trace amine associated receptor 5
chr9_+_123083540 0.154 GSN
gelsolin
chr8_-_125648576 0.153 MTSS1
metastasis suppressor 1
chr9_-_21218132 0.142 NM_021268
IFNA17
interferon, alpha 17
chr10_+_124020810 0.132 NM_144587
BTBD16
BTB (POZ) domain containing 16
chr1_+_78284176 0.124 NM_017655
GIPC2
GIPC PDZ domain containing family, member 2
chr10_-_71562520 0.118 AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr22_-_22389502 0.117 LOC91316
glucuronidase, beta/immunoglobulin lambda-like polypeptide 1 pseudogene
chr9_-_21197141 0.115 NM_002171
IFNA10
interferon, alpha 10
chr17_-_40339919 0.109 GFAP
glial fibrillary acidic protein
chr2_-_162638875 0.107 DPP4
dipeptidyl-peptidase 4
chr19_+_10057972 0.106 C19orf66
chromosome 19 open reading frame 66
chr9_-_21156609 0.105 NM_002175
IFNA21
interferon, alpha 21
chr22_-_22389524 0.105 LOC91316
glucuronidase, beta/immunoglobulin lambda-like polypeptide 1 pseudogene
chr1_+_144152864 0.104 TXNIP
thioredoxin interacting protein
chr3_-_52287297 0.101 WDR82
WD repeat domain 82
chrX_+_48505097 0.100 NM_001080489
GLOD5
glyoxalase domain containing 5
chr1_-_159369081 0.099 NM_001039711
NM_032998
DEDD

death effector domain containing

chr13_-_41433066 0.098 KIAA0564
KIAA0564
chr1_-_159369041 0.096 DEDD
death effector domain containing
chr11_-_64520964 0.093 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr1_-_158091296 0.092 C1orf204
chromosome 1 open reading frame 204
chr2_-_208763017 0.092 NM_001099334
C2orf80
chromosome 2 open reading frame 80
chr11_-_123261549 0.092 NM_001013743
TMEM225
transmembrane protein 225
chr20_-_7869068 0.090 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr19_-_48382398 0.089 NM_001130014
NM_002781
PSG5

pregnancy specific beta-1-glycoprotein 5

chr11_-_16387001 0.089 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr14_+_92188329 0.086 RIN3
Ras and Rab interactor 3
chr3_+_39826032 0.083 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr3_-_14964861 0.082 LOC100505673
hypothetical LOC100505673
chr11_+_111294810 0.080 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr9_+_35782405 0.079 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr1_+_33003847 0.074 KIAA1522
KIAA1522
chr4_-_47709717 0.074 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr12_-_10453409 0.074 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr11_-_7917642 0.073 NM_001003745
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr15_+_87540238 0.073 ABHD2
abhydrolase domain containing 2
chr8_-_37576515 0.070 LOC157860
hypothetical protein LOC157860
chr12_+_119632213 0.068 NM_001080533
UNC119B
unc-119 homolog B (C. elegans)
chr1_+_150005754 0.067 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr5_-_41249270 0.066 NM_000065
C6
complement component 6
chr12_-_61832856 0.065 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chr2_-_162638746 0.065 DPP4
dipeptidyl-peptidase 4
chr1_+_19796119 0.062


chr14_-_105542441 0.061 IGLJ3
IGHA1
IGHG1
IGHM
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_105610144 0.059 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_-_65084622 0.059 GUSB
glucuronidase, beta
chr7_+_45899080 0.059 IGFBP1
insulin-like growth factor binding protein 1
chr17_-_24426752 0.059 NM_004740
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_-_159435440 0.058 NM_005099
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr9_-_129719031 0.057 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr19_+_10058023 0.057 C19orf66
chromosome 19 open reading frame 66
chr6_-_31007905 0.055 NM_205854
SFTA2
surfactant associated 2
chr1_-_222100006 0.055 TP53BP2
tumor protein p53 binding protein, 2
chr2_-_162638790 0.055 DPP4
dipeptidyl-peptidase 4
chr1_+_107484151 0.052 NM_001113226
NM_001113228
NM_014917
NTNG1


netrin G1


chr8_-_145672525 0.052 NM_003923
FOXH1
forkhead box H1
chr14_+_92188546 0.052 RIN3
Ras and Rab interactor 3
chr1_-_205290921 0.052 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr12_-_6354650 0.051 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr8_-_57521702 0.049 NM_001135690
PENK
proenkephalin
chr4_-_160175782 0.047 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr17_+_72958330 0.047 SEPT9
septin 9
chr1_+_62835759 0.047 NM_014495
ANGPTL3
angiopoietin-like 3
chr8_-_145671947 0.046 FOXH1
forkhead box H1
chr1_+_19796044 0.045 NM_001032363
C1orf15-NBL1
C1orf151
C1ORF15-NBL1 read-through transcript
chromosome 1 open reading frame 151
chr3_-_150286812 0.045 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr1_+_36160375 0.045 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr3_+_46386636 0.044 NM_000579
NM_001100168
CCR5

chemokine (C-C motif) receptor 5

chr16_-_57309625 0.043 GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr2_+_102744921 0.043 NM_144632
TMEM182
transmembrane protein 182
chr22_+_49388427 0.043 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr6_-_25982418 0.042 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr5_+_63838183 0.040 NM_001029875
RGS7BP
regulator of G-protein signaling 7 binding protein
chr7_-_65084597 0.040 GUSB
glucuronidase, beta
chr9_-_113401921 0.040 NM_001146108
NM_001146109
PTGR1

prostaglandin reductase 1

chr7_-_65084641 0.040 GUSB
glucuronidase, beta
chr4_-_154900466 0.039


chr2_-_162638174 0.039 DPP4
dipeptidyl-peptidase 4
chr12_-_46439127 0.038 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_33003814 0.037 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr14_-_63264445 0.035 NM_030791
SGPP1
sphingosine-1-phosphate phosphatase 1
chr2_-_25418249 0.034 NM_022552
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr14_-_105804211 0.034 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr15_+_75074793 0.033 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_-_145712107 0.033 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr9_+_74326536 0.032 NM_138691
TMC1
transmembrane channel-like 1
chr3_-_38153467 0.030 ACAA1
acetyl-CoA acyltransferase 1
chr14_-_105279582 0.029


chr16_-_360509 0.028 NM_006428
MRPL28
mitochondrial ribosomal protein L28
chr3_+_14691609 0.028 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr1_+_143920424 0.027 NM_203458
NOTCH2NL
notch 2 N-terminal like
chr2_+_96672200 0.026 NM_001113382
FER1L5
fer-1-like 5 (C. elegans)
chr10_+_106004457 0.025 NM_001191002
NM_004832
GSTO1

glutathione S-transferase omega 1

chr11_-_73397929 0.022 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr6_+_30964441 0.020 NM_013994
DDR1
discoidin domain receptor tyrosine kinase 1
chrX_-_21686079 0.020 NM_014332
SMPX
small muscle protein, X-linked
chr14_-_105712630 0.019 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_-_7604569 0.019 NM_174895
PCP2
Purkinje cell protein 2
chr7_-_97439500 0.018 MGC72080
MGC72080 pseudogene
chr14_+_88099124 0.017 ZC3H14
zinc finger CCCH-type containing 14
chr6_-_56515640 0.017


chr19_-_48133089 0.017 NM_002783
PSG7
pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
chr8_-_86441115 0.016 NM_001164830
CA1
carbonic anhydrase I
chr15_+_61122957 0.016 TPM1
tropomyosin 1 (alpha)
chr19_-_5797465 0.015 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr1_+_196153122 0.015 NM_020204
LHX9
LIM homeobox 9
chr1_-_46541517 0.014 LRRC41
leucine rich repeat containing 41
chr1_+_151873134 0.014 NM_015607
C1orf77
chromosome 1 open reading frame 77
chr11_-_3818759 0.013 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr1_+_9222489 0.013 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr12_-_108736983 0.013 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr10_+_80777248 0.012 PPIF
peptidylprolyl isomerase F
chr17_+_12633504 0.012 NM_014859
ARHGAP44
Rho GTPase activating protein 44
chr11_-_3818713 0.012 RHOG
ras homolog gene family, member G (rho G)
chr11_+_65140207 0.012 NM_032223
PCNXL3
pecanex-like 3 (Drosophila)
chr11_+_71387572 0.012 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr14_+_104462210 0.012 NM_138790
PLD4
phospholipase D family, member 4
chr16_-_70591377 0.011 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr19_-_47261761 0.011 NM_002088
GRIK5
glutamate receptor, ionotropic, kainate 5
chr6_-_43592481 0.011 YIPF3
Yip1 domain family, member 3
chr4_-_89424691 0.011 PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr14_-_46190690 0.010 NM_080746
RPL10L
ribosomal protein L10-like
chr11_+_35640918 0.010 NM_017583
TRIM44
tripartite motif containing 44
chr6_-_43592670 0.010 YIPF3
Yip1 domain family, member 3
chr6_+_142510034 0.009 VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr21_-_42789369 0.008 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr14_+_104462199 0.008 PLD4
phospholipase D family, member 4
chr5_-_42211112 0.008


chr10_-_71562602 0.008 NM_001198696
NM_032797
AIFM2

apoptosis-inducing factor, mitochondrion-associated, 2

chr7_+_55999559 0.007 NM_001483
GBAS
glioblastoma amplified sequence
chr14_+_104462195 0.007 PLD4
phospholipase D family, member 4
chr14_-_105523735 0.007 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_26422495 0.007 EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr11_-_111462627 0.007 NM_012459
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr12_+_2792047 0.006 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr6_-_43592679 0.006 NM_015388
YIPF3
Yip1 domain family, member 3
chr9_-_134219950 0.005 SETX
senataxin
chr19_+_44838373 0.005 NM_001190441
LGALS16
beta-galactoside-binding lectin
chr19_-_44518465 0.005 GMFG
glia maturation factor, gamma
chr13_+_107720475 0.005 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr19_+_50086482 0.005 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr10_+_51507891 0.004 NM_018232
FAM21B
family with sequence similarity 21, member B
chr17_+_77289704 0.004 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_+_7039453 0.004


chr1_-_151873191 0.003 NM_001024210
S100A13
S100 calcium binding protein A13
chr1_+_75962630 0.001 NM_000016
NM_001127328
ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
15.33 3.20e-02 GO:0031328 positive regulation of cellular biosynthetic process
15.07 3.31e-02 GO:0009891 positive regulation of biosynthetic process

Nothing significant found in compartment category.

Nothing significant found in function category.