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Motif ID: PRRX1,2.p2

Z-value: 2.654

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_35658852	4.803	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr3_+_35697432	4.418	NM_198399	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr12_-_23993830	3.963	NM_006940	SOX5	SRY (sex determining region Y)-box 5
chr10_-_69125932	3.658	NM_013266	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr4_+_74520796	3.286	NM_001134	AFP	alpha-fetoprotein
chr7_-_83116414	3.195	NM_012431	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_+_83129641	3.029	NM_006670	TPBG	trophoblast glycoprotein
chr6_-_130578110	2.985	NM_152552	SAMD3	sterile alpha motif domain containing 3
chr13_+_22653059	2.939	NM_000231	SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr6_+_132915522	2.859	NM_053278	TAAR8	trace amine associated receptor 8
chr1_+_198263352	2.852	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr2_-_206790871	2.799	NM_001098199 NM_005279	GPR1	G protein-coupled receptor 1
chr2_+_234490781	2.719	NM_024080	TRPM8	transient receptor potential cation channel, subfamily M, member 8
chr17_-_36113502	2.697	NM_019016	KRT24	keratin 24
chr12_+_52708460	2.655	NM_004503	HOXC6	homeobox C6
chr2_-_180135559	2.646	NM_001113398	ZNF385B	zinc finger protein 385B
chr6_+_105511615	2.583	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr3_-_152541129	2.554	NM_176876	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr11_+_113280727	2.531	NM_006028	HTR3B	5-hydroxytryptamine (serotonin) receptor 3B
chr6_+_50894397	2.470	NM_003221	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr3_-_99236520	2.467	NM_001105580	GABRR3	gamma-aminobutyric acid (GABA) receptor, rho 3
chr5_+_127012611	2.386	NM_001048252	CTXN3	cortexin 3
chr14_+_28311740	2.373		C14orf23	chromosome 14 open reading frame 23
chr7_-_83108682	2.364	NM_001178129	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_85103438	2.297	NM_032379	SYTL2	synaptotagmin-like 2
chr18_-_55136673	2.291	NM_181654	CPLX4	complexin 4
chr4_+_77575276	2.208	NM_020859	SHROOM3	shroom family member 3
chr9_+_674193	2.171
chr17_-_36403910	2.132	NM_033185	KRTAP3-3	keratin associated protein 3-3
chr12_+_9871343	2.116	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chr4_+_88973144	2.107	NM_001184695 NM_001184696 NM_001184697 NM_020203	MEPE	matrix extracellular phosphoglycoprotein
chr13_+_23042722	2.098	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr6_+_49575629	2.070	NM_001010904	GLYATL3	glycine-N-acyltransferase-like 3
chr2_-_200033445	2.066		SATB2	SATB homeobox 2
chr4_-_77547481	2.058	NM_001042784	CCDC158	coiled-coil domain containing 158
chr12_-_54150188	2.058	NM_001005499	OR6C70	olfactory receptor, family 6, subfamily C, member 70
chr11_-_27698800	2.039	NM_001143805 NM_001143806 NM_170732	BDNF	brain-derived neurotrophic factor
chr10_-_95231933	2.036	NM_013451 NM_133337	MYOF	myoferlin
chr3_-_55489973	2.023		WNT5A	wingless-type MMTV integration site family, member 5A
chr6_+_132000134	1.993	NM_005021	ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3
chr3_+_35696119	1.967	NM_001025068 NM_001025069	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr4_+_158361185	1.933	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr4_-_120462705	1.923	NM_000134	FABP2	fatty acid binding protein 2, intestinal
chrX_+_99726445	1.916	NM_022144	TNMD	tenomodulin
chr6_+_7524691	1.877		DSP	desmoplakin
chr11_+_59612712	1.856	NM_000139	MS4A2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
chr4_-_77147625	1.851	NM_002416	CXCL9	chemokine (C-X-C motif) ligand 9
chr8_-_17599438	1.831	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr11_-_102001259	1.806	NM_004771	MMP20	matrix metallopeptidase 20
chr11_-_18214891	1.799	NM_006512	SAA4	serum amyloid A4, constitutive
chr14_+_60271203	1.738	NM_001177963 NM_002431	MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
chr15_+_47502666	1.728	NM_002009	FGF7	fibroblast growth factor 7
chr13_-_19703371	1.723	NM_006783	GJB6	gap junction protein, beta 6, 30kDa
chr7_-_30032649	1.721	NM_017946	FKBP14	FK506 binding protein 14, 22 kDa
chr5_-_1935764	1.700	NM_016358	IRX4	iroquois homeobox 4
chr3_-_115380539	1.696	NM_000796 NM_033663	DRD3	dopamine receptor D3
chr1_-_93030538	1.693	NM_005665	EVI5	ecotropic viral integration site 5
chr8_-_82536312	1.687	NM_001080526	FABP9	fatty acid binding protein 9, testis
chr18_+_27210737	1.666	NM_001134453 NM_177986	DSG4	desmoglein 4
chr3_-_18455207	1.665	NM_001131010	SATB1	SATB homeobox 1
chr18_+_59405513	1.661	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_+_99555387	1.646	NM_001005517	OR5K4	olfactory receptor, family 5, subfamily K, member 4
chr2_+_135312655	1.634	NM_138326	ACMSD	aminocarboxymuconate semialdehyde decarboxylase
chr10_+_111755715	1.609	NM_019903	ADD3	adducin 3 (gamma)
chr8_-_17797127	1.606	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr4_-_100575313	1.604	NM_001166504 NM_000673	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr15_+_46285789	1.599	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr5_+_174084137	1.598	NM_002449	MSX2	msh homeobox 2
chr11_-_117589283	1.584	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr3_-_162572441	1.578	NM_001040100	C3orf57	chromosome 3 open reading frame 57
chr8_-_120720200	1.573	NM_001040092 NM_001130863 NM_006209	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_-_70539922	1.570	NM_001105677	UGT2A2	UDP glucuronosyltransferase 2 family, polypeptide A2
chr2_+_234624084	1.566	NM_006944	SPP2	secreted phosphoprotein 2, 24kDa
chr8_-_122722674	1.547	NM_005328	HAS2	hyaluronan synthase 2
chr12_+_52697160	1.546		HOXC5 HOXC6	homeobox C5 homeobox C6
chr21_-_38955487	1.528	NM_001136154 NM_004449	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr10_-_21226536	1.527	NM_006393	NEBL	nebulette
chr11_-_102081654	1.526	NM_022122	MMP27	matrix metallopeptidase 27
chr8_-_17624304	1.521	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr12_+_52696908	1.493	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr4_+_71492581	1.487	NM_016519	AMBN	ameloblastin (enamel matrix protein)
chr2_+_158666627	1.470	NM_173355	UPP2	uridine phosphorylase 2
chr7_-_92693716	1.460	NM_001039372	HEPACAM2	HEPACAM family member 2
chr3_+_129124591	1.457	NM_207335	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr7_-_7541974	1.454	NM_001037763	COL28A1	collagen, type XXVIII, alpha 1
chr5_-_76970264	1.441	NM_032109	OTP	orthopedia homeobox
chr12_-_10853940	1.431	NM_023917	TAS2R9	taste receptor, type 2, member 9
chr3_+_99350859	1.426	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr14_-_56342097	1.425	NM_172337	OTX2	orthodenticle homeobox 2
chr17_-_36577949	1.401	NM_033187	KRTAP4-3	keratin associated protein 4-3
chr6_-_2696152	1.381	NM_001012418	MYLK4	myosin light chain kinase family, member 4
chr7_+_113853790	1.375	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr12_-_10846435	1.374	NM_023919	TAS2R7	taste receptor, type 2, member 7
chr7_-_25234582	1.371	NM_022150	NPVF	neuropeptide VF precursor
chr8_-_17624009	1.366	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr10_+_90474280	1.358	NM_001080518	LIPK	lipase, family member K
chr2_+_204509698	1.345	NM_012092	ICOS	inducible T-cell co-stimulator
chr4_-_41445479	1.342		PHOX2B	paired-like homeobox 2b
chr5_+_36642213	1.342	NM_001166696 NM_004172	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_116920232	1.330	NM_002160	TNC	tenascin C
chr12_-_86947276	1.329	NM_152589	C12orf50	chromosome 12 open reading frame 50
chr7_+_20653490	1.325	NM_001163942 NM_001163993 NM_178559	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr6_+_50789215	1.325	NM_172238	TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr1_+_213245507	1.322	NM_001017424	KCNK2	potassium channel, subfamily K, member 2
chr11_-_114593838	1.317		CADM1	cell adhesion molecule 1
chr4_-_41445693	1.315	NM_003924	PHOX2B	paired-like homeobox 2b
chr10_-_129581037	1.310
chr8_+_65655367	1.309	NM_152414	BHLHE22	basic helix-loop-helix family, member e22
chr12_-_90029328	1.306		LUM	lumican
chr15_+_56511466	1.302	NM_000236	LIPC	lipase, hepatic
chr14_-_20098929	1.299	NM_001001673 NM_001110356 NM_001110357 NM_001110358 NM_001110359 NM_001110360 NM_001110361	RNASE9	ribonuclease, RNase A family, 9 (non-active)
chr11_-_13474101	1.296	NM_000315	PTH	parathyroid hormone
chr7_-_28186867	1.285	NM_175061	JAZF1	JAZF zinc finger 1
chr7_-_96471544	1.284		DLX6-AS1	DLX6 antisense RNA 1 (non-protein coding)
chr6_+_46822657	1.274	NM_001162435	LOC100287718	ankyrin repeat domain containing gene
chr4_+_100651183	1.266	NM_032149	C4orf17	chromosome 4 open reading frame 17
chr3_-_55490401	1.260		WNT5A	wingless-type MMTV integration site family, member 5A
chr12_-_10850845	1.259	NM_023918	TAS2R8	taste receptor, type 2, member 8
chr17_-_36074812	1.259	NM_152349	KRT222	keratin 222
chr3_-_109730858	1.258	NM_014981	MYH15	myosin, heavy chain 15
chr12_+_18305740	1.252	NM_004570	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide
chr8_-_18710575	1.246	NM_206909	PSD3	pleckstrin and Sec7 domain containing 3
chr1_-_188713324	1.242	NM_199051	FAM5C	family with sequence similarity 5, member C
chr6_+_55300225	1.242	NM_207410	GFRAL	GDNF family receptor alpha like
chr8_-_87311624	1.239	NM_138817	SLC7A13	solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr15_+_56217686	1.234	NM_020980	AQP9	aquaporin 9
chr3_-_168580764	1.232	NM_024687	ZBBX	zinc finger, B-box domain containing
chr1_+_168898898	1.225		PRRX1	paired related homeobox 1
chr3_+_143824955	1.220	NM_002670	PLS1	plastin 1
chr11_+_101423378	1.214	NM_001195005 NM_032930	C11orf70	chromosome 11 open reading frame 70
chr7_+_38984133	1.211	NM_001166018 NM_007252	POU6F2	POU class 6 homeobox 2
chr13_+_31211678	1.198	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr12_+_8866416	1.196	NM_144670	A2ML1	alpha-2-macroglobulin-like 1
chr14_-_46882144	1.194	NM_182830	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr8_+_104900591	1.182	NM_014677	RIMS2	regulating synaptic membrane exocytosis 2
chr3_+_152934393	1.181	NM_207365	AADACL2	arylacetamide deacetylase-like 2
chr6_-_132987106	1.177	NM_001033080	TAAR2	trace amine associated receptor 2
chr1_-_229627412	1.143	NM_022051	EGLN1	egl nine homolog 1 (C. elegans)
chr5_+_36644187	1.137	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_7547552	1.135	NM_004244 NM_203416	CD163	CD163 molecule
chr11_+_120478584	1.131	NM_005422	TECTA	tectorin alpha
chr6_+_47857733	1.130	NM_181744	OPN5	opsin 5
chr4_-_44348414	1.127	NM_182592	YIPF7	Yip1 domain family, member 7
chr13_+_77007809	1.113	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr1_+_169421011	1.102	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chr5_-_13997588	1.099	NM_001369	DNAH5	dynein, axonemal, heavy chain 5
chr7_+_142053693	1.093	NM_001190487	MTRNR2L6	MT-RNR2-like 6
chr3_-_55490442	1.092		WNT5A	wingless-type MMTV integration site family, member 5A
chr7_-_107230867	1.090	NM_000111	SLC26A3	solute carrier family 26, member 3
chr10_-_21826192	1.077		C10orf114	chromosome 10 open reading frame 114
chr18_+_19826734	1.070	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr2_-_162808123	1.067	NM_004460	FAP	fibroblast activation protein, alpha
chr10_+_124310170	1.066	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr12_-_28016182	1.065	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr7_+_113842284	1.064	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr5_+_127016605	1.062	NM_001127385	CTXN3	cortexin 3
chr10_-_21826211	1.058	NM_001010911	C10orf114	chromosome 10 open reading frame 114
chr6_-_136829705	1.052	NM_001198615	MAP7	microtubule-associated protein 7
chr8_-_114518194	1.049	NM_052900 NM_198123	CSMD3	CUB and Sushi multiple domains 3
chr3_+_89239494	1.046		EPHA3	EPH receptor A3
chr11_-_123695302	1.035	NM_001002918	OR8D2	olfactory receptor, family 8, subfamily D, member 2
chr5_+_140583098	1.032	NM_018934	PCDHB14	protocadherin beta 14
chr5_-_111340421	1.028	NM_001142474 NM_001142475	C5orf13	chromosome 5 open reading frame 13
chr2_+_166137091	1.025	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr6_+_64289585	1.024		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr12_-_10215942	1.022	NM_001172632 NM_001172633 NM_002543	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1
chr14_+_91858677	1.020	NM_153648	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr4_+_71096830	1.019	NM_017855	ODAM	odontogenic, ameloblast asssociated
chr20_-_49852353	1.017	NM_020436	SALL4	sal-like 4 (Drosophila)
chr3_-_27739201	1.016		EOMES	eomesodermin
chr10_-_50269912	1.014	NM_001080520	DRGX	dorsal root ganglia homeobox
chr13_-_45323757	1.013	NM_198849	SIAH3	seven in absentia homolog 3 (Drosophila)
chr12_+_9033403	1.012	NM_005810	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr12_-_90029672	1.010	NM_002345	LUM	lumican
chr1_-_180822686	1.010	NM_021133	RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr2_+_102456193	1.003	NM_001011552	SLC9A4	solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr9_+_27099138	1.002	NM_000459	TEK	TEK tyrosine kinase, endothelial
chr2_-_180319013	1.001	NM_001113397	ZNF385B	zinc finger protein 385B
chr10_-_115413630	1.001	NM_006175 NM_198060	NRAP	nebulin-related anchoring protein
chr3_-_115960807	0.999	NM_001164344 NM_001164345	ZBTB20	zinc finger and BTB domain containing 20
chr21_-_38792173	0.999	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr12_+_106692291	0.999	NM_203436	ASCL4	achaete-scute complex homolog 4 (Drosophila)
chr1_-_214963279	0.997	NM_001438	ESRRG	estrogen-related receptor gamma
chr11_-_6005546	0.995	NM_001001917	OR56A1	olfactory receptor, family 56, subfamily A, member 1
chr3_+_116824840	0.993	NM_001130064 NM_002045	GAP43	growth associated protein 43
chr11_+_89507465	0.989	NM_005467	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2
chr3_+_99733432	0.989	NM_005290	GPR15	G protein-coupled receptor 15
chr3_-_150993299	0.989	NM_001144960	C3orf16	chromosome 3 open reading frame 16
chr1_+_67404756	0.988	NM_144701	IL23R	interleukin 23 receptor
chrX_-_15243647	0.988	NM_080873	ASB11	ankyrin repeat and SOCS box containing 11
chr3_+_174598937	0.986	NM_014932	NLGN1	neuroligin 1
chr17_-_23244499	0.981	NM_001076680	C17orf108	chromosome 17 open reading frame 108
chr4_-_87247829	0.980	NM_138981	MAPK10	mitogen-activated protein kinase 10
chr2_-_55053398	0.979
chr3_+_2908920	0.977	NM_175613	CNTN4	contactin 4
chr8_-_110730183	0.975	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr4_-_122357104	0.975	NM_001128843	TNIP3	TNFAIP3 interacting protein 3
chr4_+_74505710	0.972
chr18_+_59374372	0.969	NM_080474	SERPINB12	serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr2_-_162717159	0.966	NM_002054	GCG	glucagon

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.91	4.83e-08	GO:0032501	multicellular organismal process
1.96	2.36e-04	GO:0007275	multicellular organismal development
2.07	4.50e-04	GO:0048731	system development
1.94	1.60e-03	GO:0048856	anatomical structure development
1.82	2.00e-03	GO:0032502	developmental process
4.65	8.07e-03	GO:0001501	skeletal system development
2.95	1.05e-02	GO:0009888	tissue development
42.85	2.56e-02	GO:0060638	mesenchymal-epithelial cell signaling
2.10	3.98e-02	GO:0048513	organ development

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.30	2.39e-05	GO:0044459	plasma membrane part
1.72	6.63e-04	GO:0005886	plasma membrane
2.14	9.18e-04	GO:0005576	extracellular region
1.70	1.06e-03	GO:0071944	cell periphery
3.42	1.23e-03	GO:0030054	cell junction
38.09	6.37e-03	GO:0005916	fascia adherens
5.23	7.19e-03	GO:0005911	cell-cell junction
2.47	1.44e-02	GO:0044421	extracellular region part
28.57	1.64e-02	GO:0014704	intercalated disc
28.57	1.64e-02	GO:0044291	cell-cell contact zone
3.75	4.30e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.69	2.49e-04	GO:0004888	transmembrane receptor activity
2.31	1.01e-03	GO:0004872	receptor activity
3.18	2.69e-03	GO:0043565	sequence-specific DNA binding
2.57	1.18e-02	GO:0001071	nucleic acid binding transcription factor activity
2.57	1.18e-02	GO:0003700	sequence-specific DNA binding transcription factor activity