Motif ID: TEAD1.p2

Z-value: 2.635


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4



Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132314004 6.100 NM_001901
CTGF
connective tissue growth factor
chr4_+_184257337 5.144 NM_024949
WWC2
WW and C2 domain containing 2
chr1_-_212791597 5.071 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_212791467 5.013 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_116382089 4.939 ABLIM1
actin binding LIM protein 1
chr3_-_135575925 4.878 NM_016201
AMOTL2
angiomotin like 2
chr11_-_46896484 4.121 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr1_-_43509187 4.108 EBNA1BP2
EBNA1 binding protein 2
chrX_-_10548458 3.887 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr10_+_123862430 3.780 TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_160972606 3.694 RBMS1
RNA binding motif, single stranded interacting protein 1
chr6_-_128883125 3.586 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr15_+_61121806 3.320 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr12_-_94708641 3.201 NM_021229
NTN4
netrin 4
chr15_+_37660568 3.060 NM_003246
THBS1
thrombospondin 1
chr6_+_41712907 3.039 MDFI
MyoD family inhibitor
chr10_-_61819493 3.014 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_-_39460687 2.964 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr14_-_88090641 2.959 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr1_+_24522116 2.909 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_12599934 2.824 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_+_18680010 2.741 NM_152375
KLHDC7A
kelch domain containing 7A
chr11_-_6298284 2.725 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr1_-_24311212 2.696 NM_152372
MYOM3
myomesin family, member 3
chr16_-_62573 2.664 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr19_+_39664706 2.648 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr6_+_167445284 2.600 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr11_-_8789457 2.591 NM_139157
ST5
suppression of tumorigenicity 5
chr15_+_61122139 2.562 TPM1
tropomyosin 1 (alpha)
chr18_-_19496590 2.500 NM_173505
ANKRD29
ankyrin repeat domain 29
chr12_+_47498778 2.468 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr19_-_56204615 2.452 NM_012315
KLK9
kallikrein-related peptidase 9
chr9_+_88953378 2.416 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr12_+_26239755 2.416 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr17_-_36347197 2.351 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr6_-_75972286 2.326 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr6_+_123152044 2.227 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr11_-_2907169 2.225 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr2_-_158439868 2.222 NM_001105
ACVR1
activin A receptor, type I
chr5_-_39460787 2.217 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr17_-_37828643 2.212 NM_012232
PTRF
polymerase I and transcript release factor
chr20_-_23915431 2.170 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr10_-_125843092 2.161 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr6_-_168222645 2.148 NM_024919
FRMD1
FERM domain containing 1
chr11_-_8788765 2.148 NM_213618
ST5
suppression of tumorigenicity 5
chr19_-_59568222 2.132 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr3_-_129023850 2.130 NM_007283
MGLL
monoglyceride lipase
chr4_-_186970366 2.089 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr19_-_59568340 2.071 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr1_-_158098962 1.923 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr1_+_85819004 1.921 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr16_+_68765428 1.919 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr6_+_155453114 1.910 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr2_+_45732416 1.896 NM_005400
PRKCE
protein kinase C, epsilon
chr11_+_124294355 1.893 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr20_+_36365965 1.865 NM_001725
BPI
bactericidal/permeability-increasing protein
chr1_-_54392030 1.856 NM_201546
CDCP2
CUB domain containing protein 2
chr6_-_167491305 1.843 NM_005299
GPR31
G protein-coupled receptor 31
chr6_-_134538762 1.832 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_181422016 1.817 LAMC2
laminin, gamma 2
chr8_-_38505331 1.809 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr6_-_143307976 1.778 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr2_-_20075929 1.753 NM_002381
MATN3
matrilin 3
chr6_-_31007905 1.742 NM_205854
SFTA2
surfactant associated 2
chr6_-_31188310 1.739 NM_014070
C6orf15
chromosome 6 open reading frame 15
chr2_-_20075889 1.727 MATN3
matrilin 3
chr7_-_107558021 1.720 NM_007356
LAMB4
laminin, beta 4
chr2_+_102125616 1.719 IL1R1
interleukin 1 receptor, type I
chr1_+_181421984 1.689 LAMC2
laminin, gamma 2
chr22_+_21318779 1.662 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr6_-_42218692 1.656 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr3_+_38322430 1.651 NM_004803
SLC22A14
solute carrier family 22, member 14
chr3_-_150533948 1.641 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr11_-_85107569 1.641 NM_206929
SYTL2
synaptotagmin-like 2
chr19_-_59568483 1.638 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr11_-_85108030 1.637 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr15_+_94670160 1.627 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr14_-_22947320 1.622 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr18_+_8707368 1.607 NM_015210
KIAA0802
KIAA0802
chr8_-_108579270 1.587 NM_001146
ANGPT1
angiopoietin 1
chr1_+_183970093 1.582 NM_031935
HMCN1
hemicentin 1
chr6_+_144040751 1.556 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr8_-_116750427 1.488 TRPS1
trichorhinophalangeal syndrome I
chr6_+_158322875 1.486 NM_003898
SYNJ2
synaptojanin 2
chr1_+_61320213 1.465 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr6_+_31190505 1.459 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr3_+_138020550 1.457 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr14_-_22516271 1.425 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr5_-_37871685 1.421 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr1_+_181421796 1.421 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr1_-_16355013 1.416 NM_004431
EPHA2
EPH receptor A2
chr8_-_38444398 1.403 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr1_-_201583989 1.402 FMOD
fibromodulin
chr4_-_186815116 1.400 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr7_+_134114701 1.398 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr7_+_134114912 1.380 CALD1
caldesmon 1
chr16_-_73012740 1.366 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr6_+_158322916 1.364 SYNJ2
synaptojanin 2
chr1_+_228949752 1.355 NM_006615
NM_016452
CAPN9

calpain 9

chr6_+_116956868 1.347 NM_153036
FAM26D
family with sequence similarity 26, member D
chr2_+_113546365 1.338 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr1_-_181889070 1.326 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr3_+_9919295 1.313 NM_153483
IL17RE
interleukin 17 receptor E
chr2_+_149118791 1.296 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_-_39461054 1.290 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_-_75972473 1.278 COL12A1
collagen, type XII, alpha 1
chr5_-_148422799 1.269 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr12_-_47464143 1.229 NM_015270
ADCY6
adenylate cyclase 6
chr1_+_26358097 1.212 NM_024869
GRRP1
glycine/arginine rich protein 1
chr15_-_39973566 1.201 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr6_+_158322904 1.200 SYNJ2
synaptojanin 2
chr1_-_17179694 1.195 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr12_-_53099277 1.163 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_+_34723420 1.158 NM_001145523
RAI14
retinoic acid induced 14
chr14_-_22515725 1.143 JUB
jub, ajuba homolog (Xenopus laevis)
chr18_+_19947314 1.141 TTC39C
tetratricopeptide repeat domain 39C
chr5_-_138767654 1.121 NM_194296
SPATA24
spermatogenesis associated 24
chr7_+_134114957 1.114 CALD1
caldesmon 1
chr9_+_115970599 1.113 COL27A1
collagen, type XXVII, alpha 1
chr2_+_151922350 1.105 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_131657964 1.105 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr2_+_37282516 1.104 LOC100505876
hypothetical LOC100505876
chr7_+_115952279 1.103 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr4_-_152368492 1.101 SH3D19
SH3 domain containing 19
chr4_+_152417774 1.098 NM_183375
PRSS48
protease, serine, 48
chr17_+_71229110 1.092 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr16_-_21344158 1.090 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr22_-_20419975 1.088 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr3_+_191588354 1.086 NM_006580
CLDN16
claudin 16
chr2_-_192419896 1.067 SDPR
serum deprivation response
chr5_+_76150637 1.066 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr11_-_124311106 1.065 HEPACAM
hepatic and glial cell adhesion molecule
chr12_-_53099269 1.053 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_199704773 1.048 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr17_+_71229191 1.020 ITGB4
integrin, beta 4
chr16_+_24174975 1.016 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr6_-_31789824 1.003


chr8_-_125785611 0.999 MTSS1
metastasis suppressor 1
chr11_-_9182356 0.995 DENND5A
DENN/MADD domain containing 5A
chr1_+_20269239 0.983 NM_000929
PLA2G5
phospholipase A2, group V
chr17_+_71229151 0.981 ITGB4
integrin, beta 4
chr3_+_9919511 0.977 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr6_-_134538526 0.970 SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_53099203 0.954 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr10_-_17699309 0.935 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_+_117955890 0.935 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr5_+_140848905 0.931 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr5_+_38882017 0.926 OSMR
oncostatin M receptor
chr3_-_115825742 0.925 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr16_+_15435825 0.903 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr1_-_149698516 0.902 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr13_+_109936080 0.900 COL4A2
collagen, type IV, alpha 2
chr9_+_94776538 0.887 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr2_+_95303947 0.885 PROM2
prominin 2
chr19_+_55383249 0.884 MYH14
myosin, heavy chain 14, non-muscle
chr5_-_38631263 0.875 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr19_-_56147971 0.871 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr2_-_75641587 0.867 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr2_-_75641535 0.865 FAM176A
family with sequence similarity 176, member A
chr5_-_159672060 0.863 NM_024565
CCNJL
cyclin J-like
chr3_+_125586241 0.850 KALRN
kalirin, RhoGEF kinase
chr3_-_113842553 0.847 CCDC80
coiled-coil domain containing 80
chr5_-_159730196 0.844 NM_031908
C1QTNF2
C1q and tumor necrosis factor related protein 2
chrX_-_24241352 0.841 NM_001136233
FAM48B2
family with sequence similarity 48, member B2
chr7_+_115952325 0.837 CAV1
caveolin 1, caveolae protein, 22kDa
chr3_-_113842237 0.836 CCDC80
coiled-coil domain containing 80
chr4_-_184480572 0.829 NM_001185149
CLDN24
claudin 24
chr12_-_119172339 0.826 NM_025157
PXN
paxillin
chr15_-_97366313 0.817 NM_001102612
PGPEP1L
pyroglutamyl-peptidase I-like
chr12_-_78608873 0.813 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr11_+_1812115 0.811 NM_138567
SYT8
synaptotagmin VIII
chr3_-_113841967 0.809 CCDC80
coiled-coil domain containing 80
chr3_-_10307408 0.808 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr1_+_242281199 0.804 ZNF238
zinc finger protein 238
chr11_-_65082705 0.803 LTBP3
latent transforming growth factor beta binding protein 3
chr5_-_37871349 0.800 NM_199231
GDNF
glial cell derived neurotrophic factor
chr19_+_522260 0.799 NM_198591
BSG
basigin (Ok blood group)
chr10_+_99334069 0.795 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr16_+_22432344 0.792 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr17_+_46267603 0.792 NM_175575
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr6_+_31910623 0.791 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr11_+_57123927 0.791 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr3_-_113842350 0.788 CCDC80
coiled-coil domain containing 80
chr6_-_42017337 0.783 NM_001136125
NM_001760
CCND3

cyclin D3

chr14_-_22521544 0.783 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr19_-_51666503 0.782 PNMAL1
PNMA-like 1
chr2_-_233349469 0.779 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr10_+_102782151 0.777 SFXN3
sideroflexin 3
chr3_-_113842133 0.776 CCDC80
coiled-coil domain containing 80
chr2_+_95303922 0.774 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr11_-_124311512 0.774 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr21_+_43024936 0.771 PDE9A
phosphodiesterase 9A
chr20_-_55719946 0.766 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr1_+_216585298 0.764 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr11_+_46323575 0.756 DGKZ
diacylglycerol kinase, zeta
chr15_+_73728402 0.754 NM_153271
SNX33
sorting nexin 33
chr6_+_108987703 0.754 NM_201559
FOXO3
forkhead box O3
chr3_-_113842255 0.753 CCDC80
coiled-coil domain containing 80
chrX_+_30169977 0.751 NM_002367
MAGEB4
melanoma antigen family B, 4
chr17_-_3445873 0.751 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
7.96 3.45e-04 GO:0048514 blood vessel morphogenesis
6.52 2.10e-03 GO:0001568 blood vessel development
2.79 3.57e-03 GO:0009653 anatomical structure morphogenesis
6.06 4.02e-03 GO:0001944 vasculature development
4.18 8.92e-03 GO:0006928 cellular component movement
4.52 9.05e-03 GO:0072358 cardiovascular system development
4.52 9.05e-03 GO:0072359 circulatory system development
3.56 1.26e-02 GO:0007155 cell adhesion
3.56 1.26e-02 GO:0022610 biological adhesion
3.34 1.42e-02 GO:0040011 locomotion
4.69 1.52e-02 GO:0016477 cell migration
23.17 1.66e-02 GO:0007044 cell-substrate junction assembly
7.24 3.51e-02 GO:0001525 angiogenesis
4.26 3.69e-02 GO:0048870 cell motility
4.26 3.69e-02 GO:0051674 localization of cell

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.55 3.54e-05 GO:0044459 plasma membrane part
5.40 2.39e-04 GO:0031012 extracellular matrix
5.86 2.99e-04 GO:0005578 proteinaceous extracellular matrix
10.05 6.65e-04 GO:0044420 extracellular matrix part
1.83 1.19e-03 GO:0071944 cell periphery
2.28 3.21e-03 GO:0005576 extracellular region
1.77 4.92e-03 GO:0005886 plasma membrane
7.44 1.70e-02 GO:0005938 cell cortex
6.54 3.41e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
25.95 2.04e-03 GO:0050840 extracellular matrix binding
48.65 3.47e-03 GO:0001786 phosphatidylserine binding
7.68 4.72e-03 GO:0005539 glycosaminoglycan binding
7.10 7.75e-03 GO:0001871 pattern binding
7.10 7.75e-03 GO:0030247 polysaccharide binding
37.43 8.16e-03 GO:0001968 fibronectin binding
8.70 8.73e-03 GO:0008201 heparin binding
4.42 1.18e-02 GO:0030246 carbohydrate binding
32.44 1.29e-02 GO:0043236 laminin binding
108.10 1.48e-02 GO:0070052 collagen V binding