Motif ID: ZFP161.p2

Z-value: 1.843


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)



Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_138726737 4.246 NM_152421
FAM69B
family with sequence similarity 69, member B
chr8_+_1937711 3.566 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr11_-_1549719 3.263 NM_004420
DUSP8
dual specificity phosphatase 8
chr2_-_233501069 2.983 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr22_-_27405708 2.873 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr3_+_128830656 2.628 NM_015720
PODXL2
podocalyxin-like 2
chr20_+_20296744 2.271 NM_002196
INSM1
insulinoma-associated 1
chr13_-_78075683 2.248 NM_006237
POU4F1
POU class 4 homeobox 1
chr10_-_725522 2.223 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr10_+_105027431 1.963 INA
internexin neuronal intermediate filament protein, alpha
chr20_-_538909 1.926 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr4_-_5945596 1.880 NM_001014809
CRMP1
collapsin response mediator protein 1
chr20_-_61933012 1.859 ZBTB46
zinc finger and BTB domain containing 46
chr3_-_129689394 1.848 NM_001145662
GATA2
GATA binding protein 2
chr10_+_23521464 1.801 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr16_-_27982277 1.782 NM_001109763
GSG1L
GSG1-like
chr4_+_2031036 1.762 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr22_-_37569679 1.755


chr19_-_11452439 1.724 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr13_+_99432258 1.675 NM_007129
ZIC2
Zic family member 2 (odd-paired homolog, Drosophila)
chr1_-_11674264 1.654 NM_001127325
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr20_+_17155617 1.650 NM_002594
PCSK2
proprotein convertase subtilisin/kexin type 2
chr4_-_110443247 1.648 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr21_+_33364420 1.648 OLIG1
oligodendrocyte transcription factor 1
chr17_+_56832255 1.641 TBX2
T-box 2
chr16_+_55180767 1.628 NM_005954
MT3
metallothionein 3
chr16_+_53915971 1.627 NM_024335
IRX6
iroquois homeobox 6
chr8_+_65656164 1.584 BHLHE22
basic helix-loop-helix family, member e22
chr1_+_41022066 1.544 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr11_-_30564338 1.535 NM_001145399
MPPED2
metallophosphoesterase domain containing 2
chr3_+_127743868 1.518 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr21_+_33364316 1.513 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr20_+_17155669 1.511 PCSK2
proprotein convertase subtilisin/kexin type 2
chr11_+_627268 1.501 NM_000797
DRD4
dopamine receptor D4
chr16_-_695719 1.485 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr17_-_34015631 1.479 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr9_-_34579679 1.476 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr18_-_21184824 1.474


chr2_+_104837004 1.469


chr22_+_47263919 1.465 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr5_-_132976121 1.450 NM_015082
FSTL4
follistatin-like 4
chr14_+_104338423 1.444 ZBTB42
zinc finger and BTB domain containing 42
chr18_+_74841262 1.441 NM_171999
SALL3
sal-like 3 (Drosophila)
chr14_+_91859289 1.425 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr16_+_54782802 1.420 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr19_+_45799060 1.415 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr8_-_125809831 1.415 NM_014751
MTSS1
metastasis suppressor 1
chr4_-_109308893 1.407 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr17_+_41327808 1.404 MAPT
microtubule-associated protein tau
chr3_-_9570412 1.404 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr17_+_56831951 1.384 NM_005994
TBX2
T-box 2
chr5_-_132976094 1.383 FSTL4
follistatin-like 4
chr10_+_115793795 1.379 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr7_-_44331544 1.374 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr19_-_5291700 1.343 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr14_+_68796621 1.334 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr7_-_72822471 1.327 NM_001306
CLDN3
claudin 3
chr19_-_18867868 1.323 NM_021267
NM_198207
NM_001492
LASS1

GDF1
LAG1 homolog, ceramide synthase 1

growth differentiation factor 1
chr6_-_5952631 1.303 NM_016588
NRN1
neuritin 1
chr16_+_65754788 1.295 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr13_-_27967215 1.295 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr7_+_45580704 1.285 ADCY1
adenylate cyclase 1 (brain)
chr15_+_31390454 1.278 NM_001036
RYR3
ryanodine receptor 3
chr19_+_52215982 1.270 NM_002517
NPAS1
neuronal PAS domain protein 1
chr1_+_4614964 1.263 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr10_+_60606352 1.260 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr13_-_71338144 1.248 DACH1
dachshund homolog 1 (Drosophila)
chr13_+_48692472 1.239 NM_001507
MLNR
motilin receptor
chr10_-_28074752 1.237 NM_173576
MKX
mohawk homeobox
chr11_-_69299351 1.235 NM_002007
FGF4
fibroblast growth factor 4
chr4_+_48180033 1.226 NM_152679
SLC10A4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr15_-_81113676 1.218 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr22_-_36245155 1.217 NM_014550
CARD10
caspase recruitment domain family, member 10
chr17_+_56832492 1.212 TBX2
T-box 2
chrX_-_142549984 1.206 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr10_-_131652007 1.204 NM_001005463
EBF3
early B-cell factor 3
chr11_-_63014986 1.191 NM_001146728
NM_001146729
NM_054108
HRASLS5


HRAS-like suppressor family, member 5


chr21_+_32167175 1.183 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr1_+_11674365 1.172 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr18_-_29412148 1.171


chr8_-_61356436 1.168 NM_004056
CA8
carbonic anhydrase VIII
chr3_-_129694717 1.159 NM_032638
GATA2
GATA binding protein 2
chr1_-_49014993 1.159 NM_024603
BEND5
BEN domain containing 5
chr1_-_1525309 1.157 LOC643988
hypothetical LOC643988
chr22_-_31784328 1.152 NM_001135774
SYN3
synapsin III
chr8_+_104582151 1.149 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr17_-_16336204 1.142 NM_001113567
NM_207387
C17orf76

chromosome 17 open reading frame 76

chr3_-_171786468 1.135 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr14_+_103674812 1.130 NM_015656
KIF26A
kinesin family member 26A
chr4_-_41848874 1.127 BEND4
BEN domain containing 4
chr17_+_41327662 1.126 MAPT
microtubule-associated protein tau
chr4_+_147779492 1.117 NM_004575
POU4F2
POU class 4 homeobox 2
chr20_+_17155680 1.115 PCSK2
proprotein convertase subtilisin/kexin type 2
chr5_-_11956964 1.114 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr9_+_100745531 1.113 NM_001855
COL15A1
collagen, type XV, alpha 1
chr9_+_70509925 1.109 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr5_+_76542461 1.107 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr8_-_37941970 1.106 ADRB3
adrenergic, beta-3-, receptor
chr4_+_4912272 1.104 NM_002448
MSX1
msh homeobox 1
chr18_+_13208777 1.095 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr14_+_99507848 1.093 EVL
Enah/Vasp-like
chr17_+_41327449 1.087 NM_001123066
NM_001123067
NM_005910
NM_016834
NM_016835
NM_016841
MAPT





microtubule-associated protein tau





chr10_+_83625049 1.083 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr2_+_171280944 1.066 SP5
Sp5 transcription factor
chr1_-_215377718 1.063 NM_001134285
ESRRG
estrogen-related receptor gamma
chr10_+_94823221 1.063 NM_057157
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr11_-_6396864 1.057 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr2_+_112372671 1.035 MERTK
c-mer proto-oncogene tyrosine kinase
chr16_+_25610847 1.033 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr9_+_17568952 1.031 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr2_-_119632788 1.031 NM_182528
C1QL2
complement component 1, q subcomponent-like 2
chr4_-_41849333 1.027 BEND4
BEN domain containing 4
chr16_+_54782751 1.024 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr5_+_75734759 1.018 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_50271283 1.015 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr10_-_131652364 1.004 EBF3
early B-cell factor 3
chr13_-_26232777 1.000 NM_005288
GPR12
G protein-coupled receptor 12
chr11_-_2248757 0.992 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr12_+_2032649 0.978 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr2_-_42573980 0.976 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr17_+_4434582 0.972 NM_001114974
SMTNL2
smoothelin-like 2
chr14_-_62581656 0.971 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr19_+_38979502 0.966 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr1_-_21850874 0.962 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chrX_-_34585287 0.960 NM_031442
TMEM47
transmembrane protein 47
chr3_-_127558747 0.956 NM_014079
KLF15
Kruppel-like factor 15
chr10_-_60606195 0.955


chr4_-_109307325 0.954 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr12_+_93066370 0.950 NM_005761
PLXNC1
plexin C1
chr4_+_19864332 0.950 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chrX_-_51256166 0.949 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_18868395 0.946 LASS1
LAG1 homolog, ceramide synthase 1
chr2_-_39040981 0.945 LOC375196
hypothetical LOC375196
chr19_+_47509274 0.943 NM_173633
TMEM145
transmembrane protein 145
chr11_-_33847834 0.938 LMO2
LIM domain only 2 (rhombotin-like 1)
chr14_-_77034853 0.935 NM_182509
NM_199296
ISM2

isthmin 2 homolog (zebrafish)

chr17_+_41327792 0.935 MAPT
microtubule-associated protein tau
chr15_+_97462675 0.928 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr14_+_73128162 0.927 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr8_-_125809559 0.920 MTSS1
metastasis suppressor 1
chr15_-_75711743 0.919 NM_032808
LINGO1
leucine rich repeat and Ig domain containing 1
chr22_+_48951286 0.910 NM_001160300
NM_052839
PANX2

pannexin 2

chr8_-_133561738 0.905 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr3_+_129690735 0.904


chr3_-_135097111 0.901 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr14_+_91859904 0.900 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr8_-_144583718 0.896 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr22_+_42137955 0.894 NM_001044370
MPPED1
metallophosphoesterase domain containing 1
chr8_+_1909437 0.889 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr19_-_7845325 0.887 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr4_+_72271218 0.882 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr19_+_40325993 0.880 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr17_+_8865547 0.878 NM_004822
NTN1
netrin 1
chr10_+_24023680 0.878 NM_001098500
KIAA1217
KIAA1217
chr1_+_224803226 0.874 C1orf95
chromosome 1 open reading frame 95
chr4_+_158361185 0.872 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr11_-_64268126 0.872 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_110088330 0.871 NM_020809
ARHGAP20
Rho GTPase activating protein 20
chr1_+_154878498 0.866 BCAN
brevican
chr2_-_238813284 0.862 HES6
hairy and enhancer of split 6 (Drosophila)
chr3_-_135096986 0.860 RAB6B
RAB6B, member RAS oncogene family
chr11_-_61441536 0.860 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr14_+_69021149 0.858 NM_001161498
UPF0639
UPF0639 protein
chr16_+_1979959 0.856 NM_004209
SYNGR3
synaptogyrin 3
chrX_-_18282698 0.855 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr2_-_47650973 0.853 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr15_-_75711785 0.850 LINGO1
leucine rich repeat and Ig domain containing 1
chr12_+_48641545 0.848 NM_001651
AQP5
aquaporin 5
chr19_+_10392128 0.838 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_+_154943466 0.836 NM_001427
EN2
engrailed homeobox 2
chr13_+_112671497 0.833 MCF2L
MCF.2 cell line derived transforming sequence-like
chr10_-_104169458 0.833 PSD
pleckstrin and Sec7 domain containing
chr16_-_47873183 0.830 NM_004352
CBLN1
cerebellin 1 precursor
chr1_+_4614528 0.824 AJAP1
adherens junctions associated protein 1
chr11_-_2248374 0.821 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr2_+_112372651 0.814 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr1_-_111018798 0.812 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr2_+_936534 0.810 NM_018968
SNTG2
syntrophin, gamma 2
chr10_+_122206455 0.808 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr20_-_3097070 0.806 NM_014731
ProSAPiP1
ProSAPiP1 protein
chrX_+_38305634 0.802 NM_004615
TSPAN7
tetraspanin 7
chr1_+_224803123 0.800 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr6_+_107917965 0.795 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr18_-_70275441 0.794 NM_001044369
FAM69C
family with sequence similarity 69, member C
chr22_+_38183480 0.787 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr5_-_83716346 0.781 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chrX_-_142550535 0.776 NM_173078
SLITRK4
SLIT and NTRK-like family, member 4
chr12_+_120944174 0.772 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr7_-_27180398 0.772 NM_018951
HOXA10
homeobox A10
chr15_-_38362078 0.769 NM_001190479
LOC100131244
hypothetical protein LOC100131244
chr3_-_49882308 0.765 NM_024046
CAMKV
CaM kinase-like vesicle-associated
chr9_-_100598315 0.759 NM_173551
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6
chr22_+_42138034 0.755 MPPED1
metallophosphoesterase domain containing 1
chr5_-_146238336 0.755 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr7_+_113513828 0.754 FOXP2
forkhead box P2
chr1_-_202921103 0.754 NM_006338
NM_201630
LRRN2

leucine rich repeat neuronal 2

chr13_-_43259032 0.751 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr1_+_66031443 0.750 NM_002600
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_111019051 0.747


chr8_+_121892719 0.747



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.50 5.12e-07 GO:0007275 multicellular organismal development
2.38 7.87e-07 GO:0032502 developmental process
3.66 9.53e-07 GO:0007399 nervous system development
3.04 3.71e-06 GO:0030154 cell differentiation
2.61 4.56e-06 GO:0048731 system development
2.96 7.22e-06 GO:0048869 cellular developmental process
2.41 2.48e-05 GO:0048856 anatomical structure development
1.94 4.20e-05 GO:0032501 multicellular organismal process
3.22 1.11e-04 GO:0009653 anatomical structure morphogenesis
3.95 5.98e-04 GO:0048699 generation of neurons
5.15 7.05e-04 GO:0000904 cell morphogenesis involved in differentiation
3.72 1.34e-03 GO:0022008 neurogenesis
3.68 1.55e-03 GO:0048468 cell development
4.32 4.80e-03 GO:0000902 cell morphogenesis
4.01 5.03e-03 GO:0030182 neuron differentiation
4.10 8.52e-03 GO:0032989 cellular component morphogenesis
4.15 1.63e-02 GO:0048666 neuron development
5.57 1.84e-02 GO:0007610 behavior
4.41 2.08e-02 GO:0031175 neuron projection development
4.67 3.00e-02 GO:0007409 axonogenesis
4.50 4.04e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
3.73 4.59e-02 GO:0030030 cell projection organization
4.42 4.67e-02 GO:0048812 neuron projection morphogenesis
119.48 4.98e-02 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.40 5.50e-04 GO:0030528 transcription regulator activity
119.48 1.16e-02 GO:0004939 beta-adrenergic receptor activity
89.62 2.31e-02 GO:0051380 norepinephrine binding