Motif ID: AAAGUGC

Z-value: 1.582


Mature miRNA associated with seed AAAGUGC:

NamemiRBase Accession
hsa-miR-106a MIMAT0000103
hsa-miR-106b MIMAT0000680
hsa-miR-17 MIMAT0000070
hsa-miR-20a MIMAT0000075
hsa-miR-20b MIMAT0001413
hsa-miR-519d MIMAT0002853
hsa-miR-93 MIMAT0000093



Activity profile for motif AAAGUGC.

activity profile for motif AAAGUGC


Sorted Z-values histogram for motif AAAGUGC

Sorted Z-values for motif AAAGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAAGUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_19842309 2.967 NM_182744
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr12_-_26169074 2.752 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr2_+_159533329 2.410 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr9_-_111300350 2.339 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_19843261 2.210 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr18_-_19496590 2.189 NM_173505
ANKRD29
ankyrin repeat domain 29
chr6_+_36752244 2.152 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr6_+_21701942 2.058 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr2_+_29191711 1.910 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr4_+_89147821 1.865 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr1_+_243384868 1.809 NM_018012
KIF26B
kinesin family member 26B
chr7_-_141048358 1.805 NM_001080392
KIAA1147
KIAA1147
chr13_+_92677012 1.770 NM_005708
GPC6
glypican 6
chr18_+_18989786 1.718 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr5_+_72957736 1.717 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr15_+_66711380 1.707 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr7_-_142293382 1.664 NM_018646
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr11_+_120828058 1.662 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_-_9266251 1.627 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr8_+_102573837 1.561 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr3_-_126257425 1.540 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr2_-_19421852 1.516 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr12_+_32546243 1.510 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_+_130445394 1.502 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr18_+_19523526 1.498 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr8_+_1436938 1.486 NM_004745
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr1_-_94779727 1.481 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr7_-_28186867 1.480 NM_175061
JAZF1
JAZF zinc finger 1
chr5_-_150928697 1.475 NM_001447
FAT2
FAT tumor suppressor homolog 2 (Drosophila)
chr12_-_113606322 1.469 NM_005996
NM_016569
TBX3

T-box 3

chr14_-_88090641 1.457 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr18_+_19826734 1.428 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr15_-_50270856 1.418 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr6_+_148705421 1.384 NM_015278
SASH1
SAM and SH3 domain containing 1
chr12_+_62524778 1.346 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr2_-_161058550 1.330 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr17_+_4972410 1.329 NM_004505
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr2_+_27046952 1.280 NM_012326
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr2_+_48521411 1.276 NM_001135629
NM_001193475
NM_152994
KLRAQ1


KLRAQ motif containing 1


chr9_-_111230926 1.272 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr9_+_127550298 1.259 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr7_+_134226690 1.238 NM_033139
NM_033140
CALD1

caldesmon 1

chr4_-_141896920 1.219 NM_015130
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr21_-_42247007 1.208 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr5_+_159276317 1.205 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr3_+_42670179 1.194 NM_145166
ZBTB47
zinc finger and BTB domain containing 47
chr1_+_242281175 1.188 NM_205768
ZNF238
zinc finger protein 238
chr8_+_28407613 1.187 NM_017412
FZD3
frizzled homolog 3 (Drosophila)
chr16_+_54072969 1.171 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_+_144149794 1.164 NM_006472
TXNIP
thioredoxin interacting protein
chr2_-_156897286 1.158 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_+_118524959 1.136 NM_022169
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr5_+_172000793 1.133 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr18_-_28304392 1.114 NM_022751
FAM59A
family with sequence similarity 59, member A
chr18_+_53865455 1.113 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_35922106 1.086 NM_174902
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr9_+_98252200 1.082 NM_014282
HABP4
hyaluronan binding protein 4
chr11_+_69165018 1.064 NM_053056
CCND1
cyclin D1
chr16_+_54070302 1.060 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr16_+_70437394 1.040 NM_001137675
ATXN1L
ataxin 1-like
chr12_-_94708641 1.039 NM_021229
NTN4
netrin 4
chr18_+_19848347 1.031 NM_001135993
TTC39C
tetratricopeptide repeat domain 39C
chr14_+_22845851 1.023 NM_004050
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr8_+_107351519 0.988 NM_001198533
NM_018002
LOC346887
OXR1

similar to solute carrier family 16 (monocarboxylic acid transporters), member 14
oxidation resistance 1

chr17_-_44794325 0.984 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr11_-_107969554 0.982 NM_015065
EXPH5
exophilin 5
chr11_+_122031549 0.980 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr5_+_142130475 0.979 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr14_-_22516271 0.972 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr17_+_71292275 0.967 NM_001080419
UNK
unkempt homolog (Drosophila)
chr14_+_22911857 0.960 NM_172314
NM_022789
IL25

interleukin 25

chr6_+_139497933 0.959 NM_016217
HECA
headcase homolog (Drosophila)
chr2_+_100802923 0.954 NM_002518
NPAS2
neuronal PAS domain protein 2
chr15_+_89212888 0.951 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_+_14835472 0.940 NM_152536
FGD5
FYVE, RhoGEF and PH domain containing 5
chr1_+_150753601 0.936 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr1_+_117253882 0.934 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr4_-_40553838 0.931 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr3_+_30622905 0.926 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr7_+_20337249 0.924 NM_002214
ITGB8
integrin, beta 8
chr1_+_234372454 0.922 NM_003272
GPR137B
G protein-coupled receptor 137B
chr6_+_33530297 0.914 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr14_-_22521544 0.914 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr6_+_36754433 0.900 NM_000389
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr11_+_20001130 0.897 NM_001111019
NAV2
neuron navigator 2
chr22_-_30476119 0.897 NM_173566
PRR14L
proline rich 14-like
chr4_+_75449720 0.896 NM_001432
EREG
epiregulin
chr1_+_242283129 0.873 NM_006352
ZNF238
zinc finger protein 238
chr2_-_39201066 0.865 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr18_-_27518392 0.853 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr1_-_202647526 0.850 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr4_+_88147107 0.845 NM_005935
AFF1
AF4/FMR2 family, member 1
chr6_-_136888771 0.844 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr3_-_57088332 0.840 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr16_+_14072380 0.836 NM_014048
MKL2
MKL/myocardin-like 2
chr3_-_15349086 0.832 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr15_-_59308770 0.828 NM_134261
RORA
RAR-related orphan receptor A
chr7_-_105106844 0.822 NM_138495
ATXN7L1
ataxin 7-like 1
chr5_+_179166608 0.821 NM_001142299
SQSTM1
sequestosome 1
chr11_+_109469296 0.818 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr3_-_46012303 0.816 NM_024513
FYCO1
FYVE and coiled-coil domain containing 1
chr16_-_17472238 0.803 NM_022166
XYLT1
xylosyltransferase I
chr16_-_66007650 0.802 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr14_+_70178126 0.793 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr2_+_95194903 0.793 NM_001017396
NM_021088
ZNF2

zinc finger protein 2

chr20_+_48781457 0.790 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr22_+_21852551 0.787 NM_004327
NM_021574
BCR

breakpoint cluster region

chr1_+_109594163 0.785 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr7_+_28305464 0.784 NM_182899
CREB5
cAMP responsive element binding protein 5
chr20_+_30329096 0.777 NM_004798
KIF3B
kinesin family member 3B
chr3_-_56810869 0.777 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr10_-_14412813 0.772 NM_018027
FRMD4A
FERM domain containing 4A
chr7_+_30140868 0.767 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr22_-_20419975 0.765 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr6_+_158164269 0.761 NM_016224
SNX9
sorting nexin 9
chr7_-_100262971 0.756 NM_004444
EPHB4
EPH receptor B4
chr1_+_165564904 0.755 NM_001198783
POU2F1
POU class 2 homeobox 1
chr2_-_235070431 0.751 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr12_+_55201854 0.750 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_-_42441798 0.744 NM_004718
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr5_-_65053630 0.741 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr4_+_126457016 0.728 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr19_+_47480445 0.720 NM_015125
CIC
capicua homolog (Drosophila)
chr1_-_38097811 0.720 NM_005955
MTF1
metal-regulatory transcription factor 1
chr14_-_70345485 0.717 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr1_+_165456572 0.714 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr15_-_58671929 0.708 NM_134262
RORA
RAR-related orphan receptor A
chr13_-_22905822 0.705 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr11_+_117812282 0.700 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr14_+_35365266 0.698 NM_032352
BRMS1L
breast cancer metastasis-suppressor 1-like
chr4_+_154606900 0.697 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr16_-_11587647 0.695 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr21_-_42219849 0.692 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr16_+_51646292 0.688 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_22363036 0.688 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_151052391 0.687 NM_005168
RND3
Rho family GTPase 3
chr14_+_51188289 0.684 NM_152330
FRMD6
FERM domain containing 6
chr10_-_105604942 0.678 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr11_+_35596310 0.675 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr14_+_51025604 0.672 NM_001042481
FRMD6
FERM domain containing 6
chr7_-_111633620 0.671 NM_014705
DOCK4
dedicator of cytokinesis 4
chr15_+_66695932 0.664 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chr19_-_36531958 0.661 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr1_+_76312962 0.661 NM_001160011
NM_152996
ST6GALNAC3

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

chr2_+_36436873 0.654 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr4_-_140696740 0.652 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr8_-_116750277 0.652 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr21_+_43267703 0.651 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr22_+_18499354 0.646 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr7_-_102576570 0.634 NM_001122838
NM_198990
NAPEPLD

N-acyl phosphatidylethanolamine phospholipase D

chr2_+_183697327 0.632 NM_138285
NUP35
nucleoporin 35kDa
chr7_-_105304159 0.629 NM_020725
NM_152749
ATXN7L1

ataxin 7-like 1

chr3_+_144203061 0.628 NM_001080415
U2SURP
U2 snRNP-associated SURP domain containing
chr2_+_173394560 0.626 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_+_134114701 0.617 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr7_-_106088565 0.614 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr2_+_166034402 0.607 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_+_98132898 0.603 NM_001012761
RGMB
RGM domain family, member B
chr2_+_206255376 0.601 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr1_-_224993498 0.597 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr4_+_184257337 0.595 NM_024949
WWC2
WW and C2 domain containing 2
chr20_+_1823825 0.593 NM_001040023
SIRPA
signal-regulatory protein alpha
chr7_+_29569913 0.592 NM_175887
PRR15
proline rich 15
chr18_-_802268 0.592 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr10_+_126620681 0.588 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr5_+_76047536 0.587 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr3_-_12983959 0.586 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr15_+_84021271 0.581 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr12_+_970613 0.580 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr10_-_45410197 0.576 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8

chr2_+_192251105 0.570 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr6_-_136829705 0.569 NM_001198615
MAP7
microtubule-associated protein 7
chr6_-_136889436 0.567 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr11_-_18504939 0.562 NM_006292
TSG101
tumor susceptibility gene 101
chr6_+_130381408 0.562 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr17_-_51155073 0.559 NM_018286
TMEM100
transmembrane protein 100
chr5_-_112852425 0.559 NM_001085377
MCC
mutated in colorectal cancers
chr15_-_91432755 0.558 NM_001166287
RGMA
RGM domain family, member A
chr1_+_181871830 0.555 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_32777358 0.554 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr6_-_136913649 0.550 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr2_+_166137091 0.548 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_-_9599157 0.547 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr16_-_11588257 0.542 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr12_-_48963505 0.542 NM_001113546
NM_016357
LIMA1

LIM domain and actin binding 1

chr3_-_185461768 0.527 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_-_16869579 0.526 NM_000332
NM_001128164
ATXN1

ataxin 1

chr4_-_86106567 0.524 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr11_-_56848859 0.523 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr2_-_73193581 0.523 NM_015470
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr20_+_1822779 0.518 NM_001040022
SIRPA
signal-regulatory protein alpha
chr6_+_108722752 0.518 NM_145315
LACE1
lactation elevated 1
chr3_-_151171190 0.517 NM_002628
NM_053024
PFN2

profilin 2

chr9_+_127549437 0.516 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr6_-_159386007 0.516 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr12_+_4253143 0.515 NM_001759
CCND2
cyclin D2
chr20_+_6696744 0.515 NM_001200
BMP2
bone morphogenetic protein 2
chr1_+_28458546 0.514 NM_031459
SESN2
sestrin 2
chr3_+_192529567 0.513 NM_174908
NM_178335
CCDC50

coiled-coil domain containing 50

chr12_-_31635089 0.512 NM_144973
DENND5B
DENN/MADD domain containing 5B

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
54.59 1.41e-03 GO:0016538 cyclin-dependent protein kinase regulator activity
4.05 3.98e-03 GO:0030234 enzyme regulator activity
1.33 1.31e-02 GO:0005488 binding
6.91 1.43e-02 GO:0005083 small GTPase regulator activity
5.18 2.42e-02 GO:0030695 GTPase regulator activity
5.05 2.84e-02 GO:0060589 nucleoside-triphosphatase regulator activity