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• Activity deltas table
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Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 1.348

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_556968	1.988
chr6_+_12398514	1.872	NM_001168319 NM_001955	EDN1	endothelin 1
chr6_+_21701942	1.805	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr6_+_167445284	1.519	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr2_-_87102453	1.391	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr11_+_113280727	1.366	NM_006028	HTR3B	5-hydroxytryptamine (serotonin) receptor 3B
chr6_+_29249289	1.345	NM_030905	OR2J2	olfactory receptor, family 2, subfamily J, member 2
chr15_+_47502666	1.175	NM_002009	FGF7	fibroblast growth factor 7
chr4_+_74520796	1.173	NM_001134	AFP	alpha-fetoprotein
chr6_+_155579788	1.107	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr7_+_129771865	1.060	NM_001127441 NM_001127442 NM_080385	CPA5	carboxypeptidase A5
chr6_-_89984214	1.032	NM_002042	GABRR1	gamma-aminobutyric acid (GABA) receptor, rho 1
chr1_+_557269	1.000
chr4_+_120029426	0.999	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr12_+_54172413	0.926	NM_001005519	OR6C68	olfactory receptor, family 6, subfamily C, member 68
chr6_+_29534109	0.903	NM_030883	OR2H1	olfactory receptor, family 2, subfamily H, member 1
chr3_-_33675484	0.901		CLASP2	cytoplasmic linker associated protein 2
chr2_-_69033515	0.882	NM_182536	GKN2	gastrokine 2
chr2_-_131073329	0.874	NM_032545 NM_001079530	CFC1 CFC1B	cripto, FRL-1, cryptic family 1 cripto, FRL-1, cryptic family 1B
chr1_+_198263352	0.862	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr4_-_79322295	0.861
chr5_+_73145098	0.847		RGNEF	190 kDa guanine nucleotide exchange factor
chr6_+_36752244	0.842	NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr17_+_3324096	0.819	NM_001128085	ASPA	aspartoacylase
chr1_-_155936904	0.817	NM_052939	FCRL3	Fc receptor-like 3
chr8_-_82536312	0.814	NM_001080526	FABP9	fatty acid binding protein 9, testis
chr8_-_49996353	0.809	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr6_+_161043214	0.802	NM_000301 NM_001168338	PLG	plasminogen
chr12_+_100394787	0.790	NM_152323	SPIC	Spi-C transcription factor (Spi-1/PU.1 related)
chr2_+_178893216	0.774	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr6_+_46869052	0.750	NM_005588	MEP1A	meprin A, alpha (PABA peptide hydrolase)
chr5_-_37220702	0.745		C5orf42	chromosome 5 open reading frame 42
chr16_+_7322751	0.736	NM_145891 NM_145892 NM_145893	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_-_25041639	0.728	NM_001101339	C12orf77	chromosome 12 open reading frame 77
chr18_+_27210737	0.724	NM_001134453 NM_177986	DSG4	desmoglein 4
chr12_-_103846186	0.721	NM_032148	SLC41A2	solute carrier family 41, member 2
chr21_-_38792173	0.718	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr2_+_166137091	0.713	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr2_-_180135559	0.712	NM_001113398	ZNF385B	zinc finger protein 385B
chr1_+_63861474	0.711	NM_001172818	PGM1	phosphoglucomutase 1
chr2_-_21081694	0.692		APOB	apolipoprotein B (including Ag(x) antigen)
chr6_-_2580296	0.689	NM_152554	C6orf195	chromosome 6 open reading frame 195
chr6_+_158990982	0.675	NM_001009991	SYTL3	synaptotagmin-like 3
chr5_+_55182963	0.672	NM_139017	IL31RA	interleukin 31 receptor A
chr7_-_91632525	0.672	NM_001161528	LOC401387	leucine-rich repeat and death domain-containing protein
chr4_-_152366970	0.665	NM_001009555 NM_001128923	SH3D19	SH3 domain containing 19
chr22_+_21116283	0.660
chr4_-_77547481	0.651	NM_001042784	CCDC158	coiled-coil domain containing 158
chr1_-_205012348	0.633	NM_000572	IL10	interleukin 10
chr2_+_130995136	0.631	NM_032545 NM_001079530	CFC1 CFC1B	cripto, FRL-1, cryptic family 1 cripto, FRL-1, cryptic family 1B
chr8_+_92330691	0.631	NM_052832 NM_134266	SLC26A7	solute carrier family 26, member 7
chr6_-_42527760	0.626	NM_033502	TRERF1	transcriptional regulating factor 1
chr1_-_115039614	0.625	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr7_+_113853790	0.625	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr6_-_29163027	0.621	NM_001005226	OR2B3	olfactory receptor, family 2, subfamily B, member 3
chr1_+_13903936	0.618	NM_012231 NM_015866	PRDM2	PR domain containing 2, with ZNF domain
chr1_+_109057078	0.616	NM_001144937	FNDC7	fibronectin type III domain containing 7
chr5_-_124108672	0.614	NM_020747	ZNF608	zinc finger protein 608
chr14_-_89155078	0.609	NM_001085471	FOXN3	forkhead box N3
chr16_+_20370359	0.599	NM_001010845	ACSM2A	acyl-CoA synthetase medium-chain family member 2A
chr11_-_16454493	0.598	NM_033326	SOX6	SRY (sex determining region Y)-box 6
chr6_+_12825818	0.595	NM_030948	PHACTR1	phosphatase and actin regulator 1
chr17_+_59875623	0.591	NM_001085423	C17orf60	chromosome 17 open reading frame 60
chr2_-_207738858	0.582	NM_003709	KLF7	Kruppel-like factor 7 (ubiquitous)
chr10_+_118370441	0.577	NM_005396	PNLIPRP2	pancreatic lipase-related protein 2
chr3_-_152403636	0.574	NM_013308	GPR171	G protein-coupled receptor 171
chr17_+_25292748	0.571	NM_198529	EFCAB5	EF-hand calcium binding domain 5
chr1_+_17779528	0.571	NM_001011722	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_+_77212524	0.570	NM_032024	C10orf11	chromosome 10 open reading frame 11
chr7_-_25234582	0.568	NM_022150	NPVF	neuropeptide VF precursor
chrX_+_135058402	0.567	NM_001159700	FHL1	four and a half LIM domains 1
chr6_+_49575629	0.566	NM_001010904	GLYATL3	glycine-N-acyltransferase-like 3
chr9_+_101628829	0.561	NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr7_-_135083906	0.554	NM_205855	FAM180A	family with sequence similarity 180, member A
chr5_+_110435288	0.552	NM_033035	TSLP	thymic stromal lymphopoietin
chr9_+_117955890	0.550	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr11_-_8921155	0.545	NM_020646	ASCL3	achaete-scute complex homolog 3 (Drosophila)
chr7_-_30032649	0.544	NM_017946	FKBP14	FK506 binding protein 14, 22 kDa
chr3_+_3056307	0.544	NM_175612	CNTN4	contactin 4
chr10_-_85975263	0.543	NM_001017924	LRIT2	leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr15_+_91244563	0.538		CHD2	chromodomain helicase DNA binding protein 2
chr12_+_8557402	0.536	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr1_-_42738535	0.533		TMSB4XP1	thymosin beta 4, X-linked pseudogene 1
chr9_+_102380156	0.530	NM_001018116	MURC	muscle-related coiled-coil protein
chr1_+_242281175	0.528	NM_205768	ZNF238	zinc finger protein 238
chr3_-_69254226	0.527	NM_198271	LMOD3	leiomodin 3 (fetal)
chr5_-_88235624	0.516	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr6_-_29120930	0.512	NM_030903	OR2W1	olfactory receptor, family 2, subfamily W, member 1
chr17_-_61655915	0.510	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr1_+_203106600	0.504		NFASC	neurofascin
chr22_+_21006814	0.501
chrX_+_7147471	0.497	NM_000351	STS	steroid sulfatase (microsomal), isozyme S
chr7_+_129693938	0.493	NM_001869	CPA2	carboxypeptidase A2 (pancreatic)
chr17_-_52248248	0.490	NM_001085430	C17orf67	chromosome 17 open reading frame 67
chr4_+_54790020	0.490	NM_006206	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr6_+_167624792	0.489	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr13_+_97856148	0.486
chr5_-_134290789	0.486
chr11_-_5946299	0.485	NM_001146033	OR56A5	olfactory receptor, family 56, subfamily A, member 5
chr15_+_91244422	0.484	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr3_-_152541129	0.484	NM_176876	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr21_+_38550739	0.483	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_89870647	0.481	NM_001185072 NM_001185073 NM_012129	CLDN12	claudin 12
chr11_-_85107569	0.480	NM_206929	SYTL2	synaptotagmin-like 2
chr3_+_162697289	0.480	NM_001080440	OTOL1	otolin 1 homolog (zebrafish)
chr1_-_163680941	0.478	NM_006917	RXRG	retinoid X receptor, gamma
chr11_+_120478584	0.474	NM_005422	TECTA	tectorin alpha
chr6_+_7524691	0.471		DSP	desmoplakin
chr7_-_126670804	0.468	NM_000845	GRM8	glutamate receptor, metabotropic 8
chr7_+_150077756	0.463	NM_001162367	LOC100128542	hypothetical protein LOC100128542
chr2_-_183095308	0.461	NM_005019 NM_001003683	PDE1A	phosphodiesterase 1A, calmodulin-dependent
chr5_-_168204430	0.460
chr3_-_115960807	0.459	NM_001164344 NM_001164345	ZBTB20	zinc finger and BTB domain containing 20
chr6_-_49820030	0.458	NM_001190986 NM_006061	CRISP3	cysteine-rich secretory protein 3
chr9_-_122679283	0.457		PHF19	PHD finger protein 19
chr11_-_62668268	0.454	NM_001136506	SLC22A24	solute carrier family 22, member 24
chr2_+_33592445	0.454	NM_015376	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_-_36346240	0.453		KRT23	keratin 23 (histone deacetylase inducible)
chr1_-_197173159	0.450		LOC100131234	familial acute myelogenous leukemia related factor
chr8_+_128497038	0.450	NM_001159542	POU5F1B	POU class 5 homeobox 1B
chr1_+_203204667	0.448		NFASC	neurofascin
chr9_-_103397023	0.446	NM_147180	PPP3R2	protein phosphatase 3, regulatory subunit B, beta
chr9_-_14076901	0.442		NFIB	nuclear factor I/B
chr9_-_124280025	0.441	NM_001004451	OR1J1	olfactory receptor, family 1, subfamily J, member 1
chr11_-_4924905	0.430	NM_001005329	OR51A4	olfactory receptor, family 51, subfamily A, member 4
chr10_+_129237602	0.429	NM_001030013	NPS	neuropeptide S
chr3_+_46386636	0.425	NM_000579 NM_001100168	CCR5	chemokine (C-C motif) receptor 5
chr2_-_198248828	0.420	NM_144629	RFTN2	raftlin family member 2
chr6_+_144654565	0.420	NM_007124	UTRN	utrophin
chr1_+_168898898	0.419		PRRX1	paired related homeobox 1
chr12_-_51360439	0.419	NM_006121	KRT1	keratin 1
chr4_-_47678187	0.415	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr16_+_68765428	0.414	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr2_-_200030412	0.413		SATB2	SATB homeobox 2
chr6_+_25760352	0.413	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr19_+_40632456	0.410	NM_005306	FFAR2	free fatty acid receptor 2
chr5_-_125956996	0.410		ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr6_+_167504070	0.408	NM_001145121	TCP10L2 TCP10	t-complex 10-like 2 (mouse) t-complex 10 homolog (mouse)
chr7_+_94953148	0.406	NM_016116 NM_145872	ASB4	ankyrin repeat and SOCS box containing 4
chr11_+_59902598	0.404		MS4A7	membrane-spanning 4-domains, subfamily A, member 7
chr7_+_128136347	0.403		FAM71F1	family with sequence similarity 71, member F1
chr5_+_140573692	0.403	NM_018933	PCDHB13	protocadherin beta 13
chr11_-_4747722	0.402	NM_001004752	OR51F1	olfactory receptor, family 51, subfamily F, member 1
chr11_+_59001421	0.402	NM_001004705	OR4D10	olfactory receptor, family 4, subfamily D, member 10
chr17_-_36376663	0.401	NM_213656	KRT39	keratin 39
chr7_+_89870707	0.401		CLDN12	claudin 12
chr10_-_69736600	0.398		PBLD	phenazine biosynthesis-like protein domain containing
chr13_+_51933228	0.397		CKAP2	cytoskeleton associated protein 2
chr1_+_163780063	0.397	NM_001005214	LRRC52	leucine rich repeat containing 52
chr17_-_36209672	0.396	NM_181535	KRT28	keratin 28
chr7_-_99312591	0.394	NM_001005276	OR2AE1	olfactory receptor, family 2, subfamily AE, member 1
chr6_+_144513324	0.393	NM_003764	STX11	syntaxin 11
chr15_+_46285789	0.389	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr9_-_122679387	0.388	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr3_+_99484421	0.388	NM_001005482	OR5H2	olfactory receptor, family 5, subfamily H, member 2
chr8_-_108579270	0.386	NM_001146	ANGPT1	angiopoietin 1
chr1_-_156923111	0.384	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_-_38671741	0.383	NM_001172418 NM_152733	BTBD9	BTB (POZ) domain containing 9
chr4_-_72868598	0.381	NM_000583	GC	group-specific component (vitamin D binding protein)
chr9_+_104797413	0.380	NM_001340	CYLC2	cylicin, basic protein of sperm head cytoskeleton 2
chr11_-_4675524	0.378	NM_030774	OR51E2	olfactory receptor, family 51, subfamily E, member 2
chr1_+_115373937	0.377	NM_000549	TSHB	thyroid stimulating hormone, beta
chr1_+_195503956	0.376	NM_001193640 NM_201253	CRB1	crumbs homolog 1 (Drosophila)
chr16_-_20495126	0.375	NM_001105069 NM_182617	ACSM2B	acyl-CoA synthetase medium-chain family member 2B
chr7_+_123083096	0.374	NM_207163	LMOD2	leiomodin 2 (cardiac)
chr5_-_22889192	0.372		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr5_-_22889487	0.370	NM_004061	CDH12	cadherin 12, type 2 (N-cadherin 2)
chr17_-_36877002	0.369	NM_002278	KRT32	keratin 32
chr4_+_71492581	0.369	NM_016519	AMBN	ameloblastin (enamel matrix protein)
chr5_-_16795336	0.368		MYO10	myosin X
chr12_+_54045161	0.366	NM_001005497	OR6C75	olfactory receptor, family 6, subfamily C, member 75
chr3_-_152517204	0.364	NM_023915	GPR87	G protein-coupled receptor 87
chr1_+_205344200	0.364	NM_000715	C4BPA	complement component 4 binding protein, alpha
chr1_+_185064654	0.362	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr18_+_19826734	0.360	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr12_+_26096757	0.359	NM_001164746	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr15_+_100163424	0.359	NM_001005326	OR4F6	olfactory receptor, family 4, subfamily F, member 6
chr6_-_25982418	0.358	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr19_+_15699833	0.358	NM_013939	OR10H2	olfactory receptor, family 10, subfamily H, member 2
chr12_+_79362256	0.357	NM_001145026	PTPRQ	protein tyrosine phosphatase, receptor type, Q
chr12_-_7547552	0.356	NM_004244 NM_203416	CD163	CD163 molecule
chr1_+_61642287	0.355		NFIA	nuclear factor I/A
chr1_-_53972464	0.354	NM_147193	GLIS1	GLIS family zinc finger 1
chr7_+_113842284	0.353	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr21_+_24722913	0.352		FLJ42200	FLJ42200 protein
chr1_+_242281199	0.351		ZNF238	zinc finger protein 238
chr2_+_158666627	0.350	NM_173355	UPP2	uridine phosphorylase 2
chr12_+_97513644	0.350		SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chrX_-_15243647	0.350	NM_080873	ASB11	ankyrin repeat and SOCS box containing 11
chr11_+_59902530	0.348	NM_021201 NM_206938 NM_206939 NM_206940	MS4A7	membrane-spanning 4-domains, subfamily A, member 7
chr8_-_7207899	0.348	NM_001164457	ZNF705G	zinc finger protein 705G
chr11_-_113971607	0.347		FAM55D	family with sequence similarity 55, member D
chr18_+_27425727	0.347	NM_000371	TTR	transthyretin
chr4_-_185376012	0.346	NM_153343	ENPP6	ectonucleotide pyrophosphatase/phosphodiesterase 6
chr17_-_36444626	0.346	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr17_-_36294962	0.344	NM_019010	KRT20	keratin 20
chr1_-_12830728	0.342	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr3_+_25445071	0.342		RARB	retinoic acid receptor, beta
chr20_-_49747397	0.340		ATP9A	ATPase, class II, type 9A
chr3_-_11660395	0.340	NM_001128219	VGLL4	vestigial like 4 (Drosophila)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
6.22	1.01e-03	GO:0007166	cell surface receptor linked signaling pathway
83.54	2.62e-02	GO:0035272	exocrine system development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
39.49	1.89e-02	GO:0005230	extracellular ligand-gated ion channel activity