Motif ID: AGCAGCG

Z-value: 1.438


Mature miRNA associated with seed AGCAGCG:

NamemiRBase Accession
hsa-miR-503 MIMAT0002874



Activity profile for motif AGCAGCG.

activity profile for motif AGCAGCG


Sorted Z-values histogram for motif AGCAGCG

Sorted Z-values for motif AGCAGCG



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_4253143 4.218 NM_001759
CCND2
cyclin D2
chr9_-_27519434 3.158 NM_024761
MOBKL2B
MOB1, Mps One Binder kinase activator-like 2B (yeast)
chr6_-_144427340 2.590 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr20_+_48781457 2.536 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr2_-_72228427 2.099 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr10_+_88506320 2.076 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr1_-_48235148 1.930 NM_001194986
LOC388630
UPF0632 protein A
chr20_-_1113116 1.920 NM_018354
C20orf46
chromosome 20 open reading frame 46
chr16_-_87535106 1.880 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr22_+_24290738 1.766 NM_005160
ADRBK2
adrenergic, beta, receptor kinase 2
chr12_+_56230110 1.590 NM_004984
KIF5A
kinesin family member 5A
chr5_+_140187746 1.561 NM_018909
NM_031848
NM_031849
PCDHA6


protocadherin alpha 6


chr5_+_140325930 1.543 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr11_-_13474101 1.500 NM_000315
PTH
parathyroid hormone
chr2_-_219633481 1.450 NM_002181
IHH
Indian hedgehog
chr1_+_65385799 1.442 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr5_+_140160966 1.374 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr5_+_140215778 1.361 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr5_+_140235114 1.338 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr14_-_87863003 1.329 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr5_+_140166842 1.292 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr12_+_56435042 1.278 NM_138396
MARCH9
membrane-associated ring finger (C3HC4) 9
chr15_-_27650218 1.241 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr12_-_23993830 1.241 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr22_+_38770610 1.228 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr5_+_140194152 1.222 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr12_-_55168168 1.208 NM_013267
GLS2
glutaminase 2 (liver, mitochondrial)
chr6_-_94185780 1.199 NM_004440
EPHA7
EPH receptor A7
chr16_-_49742008 1.172 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr16_+_49139694 1.167 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr9_-_10602722 1.157 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr4_-_77163609 1.149 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr15_+_45263517 1.106 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr6_+_73388291 1.078 NM_001160130
NM_001160132
NM_001160133
NM_001160134
NM_019842
KCNQ5




potassium voltage-gated channel, KQT-like subfamily, member 5




chr3_+_123385219 1.039 NM_000388
CASR
calcium-sensing receptor
chr5_+_140227951 1.015 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr18_+_74841262 1.012 NM_171999
SALL3
sal-like 3 (Drosophila)
chr12_-_7916686 1.006 NM_153449
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr13_-_45859635 0.988 NM_025113
C13orf18
chromosome 13 open reading frame 18
chr12_-_108989882 0.986 NM_207435
C12orf76
chromosome 12 open reading frame 76
chr5_+_140286485 0.980 NM_018898
NM_031882
PCDHAC1

protocadherin alpha subfamily C, 1

chr19_-_16599986 0.969 NM_004831
MED26
mediator complex subunit 26
chr20_+_19141282 0.927 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr5_+_140181405 0.925 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr20_+_44083667 0.921 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr4_+_154083584 0.908 NM_033393
FHDC1
FH2 domain containing 1
chr1_+_78017894 0.900 NM_198549
FAM73A
family with sequence similarity 73, member A
chr9_-_111300350 0.898 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr4_-_41445693 0.893 NM_003924
PHOX2B
paired-like homeobox 2b
chr18_+_53253775 0.888 NM_004852
ONECUT2
one cut homeobox 2
chr6_-_97391779 0.880 NM_001143957
NM_030784
GPR63

G protein-coupled receptor 63

chr10_-_128884411 0.873 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr17_+_38088097 0.857 NM_003632
CNTNAP1
contactin associated protein 1
chr22_+_38903825 0.851 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr1_-_205290921 0.823 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr16_-_49742651 0.817 NM_002968
SALL1
sal-like 1 (Drosophila)
chr7_-_15692798 0.806 NM_005924
MEOX2
mesenchyme homeobox 2
chr4_-_78959532 0.804 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr5_-_148013908 0.796 NM_000870
HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr1_-_85439315 0.778 NM_032184
SYDE2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr8_+_95722516 0.775 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr9_+_494661 0.774 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr18_-_44723116 0.771 NM_001190823
SMAD7
SMAD family member 7
chr12_-_101396459 0.760 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_+_166644420 0.741 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr11_-_72530605 0.732 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr18_-_44729700 0.730 NM_001190822
SMAD7
SMAD family member 7
chr5_+_140200995 0.718 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr2_-_36384 0.715 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr4_-_153675602 0.714 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr16_-_66827449 0.710 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr8_-_93176618 0.710 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr4_-_82612049 0.709 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chr18_-_30057512 0.707 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr1_+_65386359 0.696 NM_013410
AK4
adenylate kinase 4
chr3_-_53356573 0.670 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr14_-_36058648 0.661 NM_003317
NKX2-1
NK2 homeobox 1
chr5_-_76970264 0.648 NM_032109
OTP
orthopedia homeobox
chr5_+_140207540 0.643 NM_014005
NM_031857
PCDHA9

protocadherin alpha 9

chr12_-_69600780 0.642 NM_002849
PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_140146059 0.641 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr10_-_21503025 0.638 NM_001173484
NM_213569
NEBL

nebulette

chr12_-_116283793 0.633 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr10_+_103103797 0.630 NM_003939
NM_033637
BTRC

beta-transducin repeat containing

chr2_-_98646367 0.628 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_75427644 0.624 NM_003655
CBX4
chromobox homolog 4
chr9_-_111122826 0.621 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr1_-_52604405 0.616 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr11_-_44288188 0.614 NM_021926
ALX4
ALX homeobox 4
chr14_-_36059084 0.595 NM_001079668
NKX2-1
NK2 homeobox 1
chr12_-_38123027 0.593 NM_001173463
NM_001173464
NM_001173465
NM_017641
KIF21A



kinesin family member 21A



chr2_+_149349242 0.589 NM_004522
KIF5C
kinesin family member 5C
chr17_-_2250967 0.585 NM_020310
MNT
MAX binding protein
chr20_-_44713466 0.581 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr14_+_101297887 0.579 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr14_-_87859284 0.573 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr3_+_123385870 0.563 NM_001178065
CASR
calcium-sensing receptor
chr5_+_140154627 0.555 NM_018905
NM_031495
PCDHA2

protocadherin alpha 2

chr17_+_63252087 0.546 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr17_+_32368611 0.544 NM_005568
LHX1
LIM homeobox 1
chr17_+_56032271 0.542 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr8_-_93177057 0.541 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr2_+_231610438 0.541 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr18_-_59137488 0.540 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr12_-_61283474 0.536 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr5_-_132976121 0.533 NM_015082
FSTL4
follistatin-like 4
chr1_-_181654124 0.532 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr19_-_56215084 0.528 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr14_-_98807574 0.519 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr4_+_76077229 0.519 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr18_-_30056431 0.504 NM_001198547
NOL4
nucleolar protein 4
chr17_+_16886491 0.485 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr8_+_100025806 0.485 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr10_+_104667991 0.483 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr17_-_34015631 0.481 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr11_-_60685454 0.474 NM_017966
VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
chr11_-_73787065 0.471 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr12_-_69434598 0.471 NM_130846
PTPRR
protein tyrosine phosphatase, receptor type, R
chr10_-_94040779 0.468 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr18_-_59185330 0.467 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr6_+_135544138 0.466 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr3_+_151609395 0.466 NM_014779
TSC22D2
TSC22 domain family, member 2
chr18_-_33399997 0.465 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr7_+_138566770 0.460 NM_173569
UBN2
ubinuclein 2
chr5_+_139473873 0.458 NM_005859
PURA
purine-rich element binding protein A
chr11_-_8571988 0.456 NM_030906
STK33
serine/threonine kinase 33
chr19_-_56214765 0.455 NM_145888
KLK10
kallikrein-related peptidase 10
chr2_-_121759237 0.451 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr3_-_129777618 0.448 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr3_-_159306532 0.447 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr16_-_87570716 0.444 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr12_-_101398503 0.438 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr18_+_53170718 0.437 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_+_56275510 0.433 NM_007250
NM_001159296
KLF8

Kruppel-like factor 8

chr18_-_44731078 0.428 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr2_+_154436670 0.426 NM_052917
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr20_+_44091219 0.426 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr1_+_226261374 0.419 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr1_-_238842071 0.415 NM_022469
GREM2
gremlin 2
chr22_+_40702709 0.411 NM_019106
NM_145733
SEPT3

septin 3

chr2_+_65308332 0.408 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr10_-_103525646 0.405 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr6_+_71179826 0.404 NM_001105531
NM_020819
FAM135A

family with sequence similarity 135, member A

chr1_-_50661716 0.402 NM_032110
DMRTA2
DMRT-like family A2
chr5_+_170779264 0.397 NM_003862
FGF18
fibroblast growth factor 18
chr12_-_49708279 0.395 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_+_140420500 0.395 NM_001195278
LOC100131199
transmembrane protein 178-like
chr1_-_149955415 0.387 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr8_-_4839670 0.381 NM_033225
CSMD1
CUB and Sushi multiple domains 1
chr13_-_20374895 0.378 NM_022459
XPO4
exportin 4
chr9_-_130574007 0.377 NM_006336
ZER1
zer-1 homolog (C. elegans)
chr1_-_149955870 0.376 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr4_-_146320243 0.370 NM_001102653
OTUD4
OTU domain containing 4
chr6_-_134537699 0.370 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_118740069 0.369 NM_171997
USP2
ubiquitin specific peptidase 2
chr4_-_68898294 0.369 NM_001031732
NM_133370
YTHDC1

YTH domain containing 1

chr4_+_72271218 0.364 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr2_+_61098200 0.364 NM_002618
PEX13
peroxisomal biogenesis factor 13
chr9_+_70584739 0.363 NM_138333
FAM122A
family with sequence similarity 122A
chr10_+_103882776 0.361 NM_015062
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr11_+_45899747 0.359 NM_152312
GYLTL1B
glycosyltransferase-like 1B
chr12_-_55686466 0.358 NM_014830
ZBTB39
zinc finger and BTB domain containing 39
chr19_-_55706156 0.355 NM_138334
JOSD2
Josephin domain containing 2
chr3_-_180272291 0.349 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr4_+_167013859 0.347 NM_012464
TLL1
tolloid-like 1
chr12_-_7979896 0.338 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_-_24645289 0.336 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr1_-_158136521 0.331 NM_012337
CCDC19
coiled-coil domain containing 19
chr1_+_179719338 0.331 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr2_+_151974849 0.330 NM_001177665
RIF1
RAP1 interacting factor homolog (yeast)
chr2_-_220116062 0.329 NM_001195731
CHPF
chondroitin polymerizing factor
chr14_-_19999475 0.326 NM_001100814
NM_144568
TMEM55B

transmembrane protein 55B

chr1_+_160734218 0.325 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr3_-_131095061 0.324 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr12_-_106679038 0.322 NM_012406
PRDM4
PR domain containing 4
chr19_-_45016587 0.314 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr19_-_14177980 0.311 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr14_+_101345878 0.306 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr5_-_95323353 0.304 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr18_+_27926566 0.301 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr5_+_140241976 0.300 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr15_-_91433165 0.299 NM_020211
RGMA
RGM domain family, member A
chr17_+_22645232 0.298 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr3_+_11009419 0.297 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr13_+_99056887 0.291 NM_206808
CLYBL
citrate lyase beta like
chr14_-_38971370 0.289 NM_203301
FBXO33
F-box protein 33
chr7_+_113842284 0.288 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr10_-_93992982 0.286 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr3_+_134775946 0.284 NM_001134423
CDV3
CDV3 homolog (mouse)
chr12_-_23628774 0.279 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chr14_-_30746431 0.279 NM_015382
HECTD1
HECT domain containing 1
chr11_+_9552809 0.278 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr4_-_153493133 0.277 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr11_-_1725924 0.274 NM_001170820
LOC402778
CD225 family protein FLJ76511
chr22_-_49413326 0.272 NM_000487
NM_001085425
NM_001085426
NM_001085427
NM_001085428
ARSA




arylsulfatase A




chr16_-_23068010 0.271 NM_020718
USP31
ubiquitin specific peptidase 31
chr12_-_52960168 0.269 NM_012117
CBX5
chromobox homolog 5
chrX_-_139414890 0.266 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr17_-_62671767 0.263 NM_014877
HELZ
helicase with zinc finger
chr18_-_43711452 0.262 NM_001003652
NM_001135937
SMAD2

SMAD family member 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
27.39 9.94e-08 GO:0007156 homophilic cell adhesion
14.48 1.97e-06 GO:0016337 cell-cell adhesion
5.09 1.29e-05 GO:0007399 nervous system development
3.18 7.65e-05 GO:0048856 anatomical structure development
2.79 3.03e-04 GO:0032502 developmental process
2.92 3.28e-04 GO:0007275 multicellular organismal development
3.19 4.46e-04 GO:0048731 system development
2.29 9.99e-04 GO:0032501 multicellular organismal process
5.91 3.72e-03 GO:0007155 cell adhesion
5.91 3.72e-03 GO:0022610 biological adhesion
112.03 3.84e-02 GO:0021889 olfactory bulb interneuron differentiation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.27 1.30e-03 GO:0005887 integral to plasma membrane
4.20 1.55e-03 GO:0031226 intrinsic to plasma membrane
2.88 1.28e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
6.46 3.44e-04 GO:0005509 calcium ion binding