Motif ID: AR.p2

Z-value: 1.020


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor



Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_22693333 1.986 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr2_-_56266408 1.612 LOC100129434
hypothetical LOC100129434
chr7_+_149778815 1.424 GIMAP8
GTPase, IMAP family member 8
chr1_+_43837096 1.348 PTPRF
protein tyrosine phosphatase, receptor type, F
chr8_-_7427584 1.336 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr6_+_18495559 1.258 NM_182757
RNF144B
ring finger protein 144B
chr8_+_7610374 1.232 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr14_-_105644300 1.184 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr8_+_7648613 1.119 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr8_+_7663908 1.078 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr8_+_7139945 1.076 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chr8_-_7404643 1.069 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr8_+_7618022 1.038 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr8_+_7633318 1.016 NM_001164450
FAM90A8
family with sequence similarity 90, member A8
chrX_+_151833641 1.013 NM_001178106
NM_001178107
NM_001178108
NM_001178109
NM_001178110
NM_007150
ZNF185





zinc finger protein 185 (LIM domain)





chr7_+_149778869 0.997 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr8_+_7656261 0.966 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr12_+_111900650 0.786 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr3_+_185537969 0.770 NM_144635
FAM131A
family with sequence similarity 131, member A
chr14_-_106270497 0.755 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr15_+_71522551 0.751 NM_001042367
C15orf60
chromosome 15 open reading frame 60
chr14_-_105796665 0.747 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr6_+_31746706 0.661 NM_021221
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr14_-_105796268 0.661 ZCWPW2
IGHV3-23
IGKV3-20
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
chr1_-_20122638 0.646 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr14_-_105862080 0.621 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr1_+_22852268 0.615 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr14_-_106064887 0.599 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr1_-_144426918 0.569 NM_007053
CD160
CD160 molecule
chr21_+_43024936 0.559 PDE9A
phosphodiesterase 9A
chr4_+_154397975 0.549 TRIM2
tripartite motif containing 2
chr19_-_59568483 0.498 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr8_-_23233426 0.463 LOXL2
lysyl oxidase-like 2
chr2_+_134728299 0.431 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr8_+_7132323 0.425 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr2_+_11190629 0.420 NM_182500
C2orf50
chromosome 2 open reading frame 50
chr3_-_58538530 0.413 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr3_-_58538110 0.412 FAM107A
family with sequence similarity 107, member A
chr7_-_131483925 0.401 PLXNA4
plexin A4
chr1_-_154727014 0.391 MEF2D
myocyte enhancer factor 2D
chr8_+_7124701 0.363 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr17_-_3442871 0.356 NM_080706
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr5_-_16791346 0.348 MYO10
myosin X
chr6_+_29187565 0.348 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr8_+_7101835 0.343 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr1_+_12108542 0.340 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr20_-_23679558 0.338 NM_001898
CST1
cystatin SN
chr14_-_105763152 0.333 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr9_-_132759045 0.315 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr20_+_39402834 0.311 NM_022896
LPIN3
lipin 3
chr9_+_94776538 0.305 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr10_+_75343352 0.295 PLAU
plasminogen activator, urokinase
chr8_+_11877238 0.294 NM_001033017
DEFB135
defensin, beta 135
chr10_-_116434102 0.289 ABLIM1
actin binding LIM protein 1
chr14_-_105817101 0.289


chr1_+_199130571 0.287 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr1_+_13367840 0.285 NM_001045480
PRAMEF17
PRAMEF16
PRAME family member 17
PRAME family member 16
chr17_-_45619038 0.282 COL1A1
collagen, type I, alpha 1
chr3_+_9933763 0.278 NM_032732
NM_153460
NM_153461
IL17RC


interleukin 17 receptor C


chr1_+_13588674 0.276 NM_001099851
PRAMEF17
PRAME family member 17
chr15_+_83092525 0.268 ZNF592
zinc finger protein 592
chr14_-_106084519 0.262 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_+_60109319 0.259 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr11_+_111602287 0.250 NM_000317
PTS
6-pyruvoyltetrahydropterin synthase
chr22_+_20929199 0.247 NM_007128
VPREB1
pre-B lymphocyte 1
chr14_-_106282128 0.245 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_60858611 0.242 DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr6_-_134415311 0.238 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr5_-_149304475 0.236 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr7_-_150576660 0.231 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_-_164614335 0.227 NM_032136
TKTL2
transketolase-like 2
chr10_+_685887 0.211 C10orf108
chromosome 10 open reading frame 108
chr4_+_1923629 0.210 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr1_+_24522116 0.209 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr2_-_231498184 0.202 NM_005683
GPR55
G protein-coupled receptor 55
chr12_+_10054492 0.199 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chr1_+_144149794 0.194 NM_006472
TXNIP
thioredoxin interacting protein
chr11_+_113165134 0.193 LOC390251
SH3-domain GRB2-like 1 pseudogene
chr20_-_42249146 0.189 JPH2
junctophilin 2
chr14_+_20226762 0.183 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr15_+_22772545 0.180 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_+_179269766 0.180 MR1
major histocompatibility complex, class I-related
chr16_-_20246309 0.180 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr19_+_6981593 0.179 NM_001136507
MBD3L5
methyl-CpG-binding domain protein 3-like 5-like
chr6_-_31007905 0.178 NM_205854
SFTA2
surfactant associated 2
chr8_+_22909305 0.177 NM_001160037
RHOBTB2
Rho-related BTB domain containing 2
chr19_+_55164668 0.172 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr1_+_20227480 0.159 PLA2G5
phospholipase A2, group V
chr1_-_171441234 0.159 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr16_+_70117523 0.158 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr2_+_241193492 0.158 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr3_+_52254782 0.154 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr7_-_150576957 0.152 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_+_71713324 0.151 NM_031889
ENAM
enamelin
chr6_+_38798529 0.143 NM_001371
DNAH8
dynein, axonemal, heavy chain 8
chr1_-_1139358 0.143 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr13_+_112825113 0.137 NM_000504
F10
coagulation factor X
chr3_+_46423682 0.134 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr19_+_4742727 0.129 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr14_+_95740916 0.129 BDKRB2
bradykinin receptor B2
chr5_+_23543480 0.125 NM_020227
PRDM9
PR domain containing 9
chr16_-_66535457 0.119 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr14_+_85069217 0.118


chr3_-_153541468 0.118 NM_001123228
TMEM14E
transmembrane protein 14E
chr20_-_23617606 0.117 NM_001899
CST4
cystatin S
chr4_+_166348273 0.106 KLHL2
kelch-like 2, Mayven (Drosophila)
chr14_-_105762742 0.101


chr1_+_233597350 0.099 NM_001079515
NM_003193
TBCE

tubulin folding cofactor E

chr18_+_12981329 0.099 NM_032142
CEP192
centrosomal protein 192kDa
chr14_-_105657378 0.092 IGHV4-31
immunoglobulin heavy variable 4-31
chr1_+_111963920 0.092 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr1_+_151655623 0.090 NM_176823
S100A7A
S100 calcium binding protein A7A
chr8_-_62764839 0.090 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr5_-_176869943 0.086 NM_001144875
NM_001144876
DOK3

docking protein 3

chr1_+_149395728 0.086 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr6_+_31838751 0.086 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr17_-_77638264 0.085 FASN
fatty acid synthase
chr1_-_27825633 0.084 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr17_+_35425139 0.083 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr16_-_66528235 0.083 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr3_+_185515543 0.083 NM_182917
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr14_-_106289751 0.083 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chrX_+_37735013 0.077 NM_012274
CXorf27
chromosome X open reading frame 27
chr12_+_50633430 0.070 NM_020327
ACVR1B
activin A receptor, type IB
chr17_-_37599953 0.069 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr6_-_154873480 0.067 CNKSR3
CNKSR family member 3
chr21_-_34806373 0.067 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr15_+_83092806 0.063 NM_014630
ZNF592
zinc finger protein 592
chr11_-_65395248 0.062 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr3_+_185515108 0.057 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chrX_-_117003310 0.057 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr1_+_226462363 0.053 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr1_+_1374931 0.053 NM_001039211
ATAD3C
ATPase family, AAA domain containing 3C
chr19_+_44591589 0.049


chr15_+_50098700 0.047 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr11_-_64284762 0.046 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr9_+_134026836 0.044 NTNG2
netrin G2
chr17_+_7264366 0.040 NM_199339
SPEM1
spermatid maturation 1
chr2_+_28572441 0.033 NM_001170585
NM_153021
PLB1

phospholipase B1

chr19_-_46626474 0.030 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr20_-_36191623 0.029 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr1_-_157950898 0.028 NM_000567
CRP
C-reactive protein, pentraxin-related
chr20_+_86121 0.027 NM_139074
DEFB127
defensin, beta 127
chr1_-_155053124 0.026 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr1_+_233597385 0.025 TBCE
tubulin folding cofactor E
chr7_+_142670624 0.025 NM_001143679
NM_001143680
NM_001143681
NM_015917
GSTK1



glutathione S-transferase kappa 1



chr12_-_102874980 0.019 NM_001135570
C12orf73
chromosome 12 open reading frame 73
chr1_-_155052562 0.017 NM_001161443
SH2D2A
SH2 domain containing 2A
chr10_+_102748062 0.016 LZTS2
leucine zipper, putative tumor suppressor 2
chr22_+_22363047 0.013 NM_153615
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr13_-_99983945 0.012 NM_033110
A2LD1
AIG2-like domain 1
chr21_+_30886629 0.011 NM_181605
KRTAP6-3
keratin associated protein 6-3
chr16_-_727889 0.009 NARFL
nuclear prelamin A recognition factor-like
chr4_+_41678469 0.009 NM_001029955
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr2_+_87536174 0.009 NCRNA00152
non-protein coding RNA 152
chr17_+_36599664 0.009 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr2_+_87536106 0.007 NCRNA00152
non-protein coding RNA 152
chr12_+_49604782 0.006 NM_014033
METTL7A
methyltransferase like 7A
chr11_+_63060848 0.005 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr22_-_41353575 0.004 CYB5R3
cytochrome b5 reductase 3
chr5_+_95008236 0.004 NM_001131066
NM_001131065
NM_173362
RFESD


Rieske (Fe-S) domain containing


chr3_-_121883647 0.004 HGD
homogentisate 1,2-dioxygenase
chr1_-_148249152 0.004 NM_020205
OTUD7B
OTU domain containing 7B
chr18_+_30652223 0.003 NM_001198942
NM_001198944
NM_032980
NM_032981
DTNA



dystrobrevin, alpha




Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
6.48 1.40e-04 GO:XXXXXXX unannotated
5.89 2.08e-02 GO:0005624 membrane fraction
5.71 2.41e-02 GO:0005626 insoluble fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
134.46 2.01e-11 GO:0003823 antigen binding
4.25 4.49e-04 GO:0008270 zinc ion binding
3.74 1.28e-03 GO:0046914 transition metal ion binding