Motif ID: ATF6.p2

Z-value: 0.865


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6



Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_31782169 1.305 PAX6
paired box 6
chrX_+_101267315 1.229 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr2_-_27384617 1.158 NM_003353
UCN
urocortin
chr11_+_65945050 1.153 NM_178864
NPAS4
neuronal PAS domain protein 4
chr17_+_56884560 0.987 TBX4
T-box 4
chr3_-_24511180 0.979 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr1_-_50661716 0.936 NM_032110
DMRTA2
DMRT-like family A2
chrX_-_139414890 0.928 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr4_-_111763356 0.924 PITX2
paired-like homeodomain 2
chr10_+_50488352 0.910 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr7_-_72822471 0.840 NM_001306
CLDN3
claudin 3
chr1_-_110414756 0.832 NM_006492
ALX3
ALX homeobox 3
chr11_-_31796061 0.808 NM_001127612
PAX6
paired box 6
chr2_+_220116986 0.782 NM_001005209
TMEM198
transmembrane protein 198
chr7_-_35260213 0.775 NM_001077653
NM_001166220
TBX20

T-box 20

chr22_-_42589543 0.763 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr2_+_220117009 0.759 TMEM198
transmembrane protein 198
chr17_-_72045218 0.755 NM_134268
CYGB
cytoglobin
chr4_-_111763655 0.753 NM_000325
PITX2
paired-like homeodomain 2
chr3_-_24511456 0.752 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr19_-_51608665 0.729 NM_032040
CCDC8
coiled-coil domain containing 8
chr7_-_19123765 0.726 TWIST1
twist homolog 1 (Drosophila)
chr14_+_100362204 0.702 MEG3
maternally expressed 3 (non-protein coding)
chr11_-_118740069 0.701 NM_171997
USP2
ubiquitin specific peptidase 2
chr8_-_22606653 0.691 NM_004430
EGR3
early growth response 3
chr10_-_131652364 0.680 EBF3
early B-cell factor 3
chr5_-_176760242 0.679 NM_001029886
PFN3
profilin 3
chr19_+_18584666 0.668 NM_012109
TMEM59L
transmembrane protein 59-like
chr7_-_19123787 0.663 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr11_-_75599433 0.660 WNT11
wingless-type MMTV integration site family, member 11
chr10_+_22674379 0.660 NM_012443
NM_172242
SPAG6

sperm associated antigen 6

chr11_+_108798047 0.659 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr11_-_118739838 0.651 USP2
ubiquitin specific peptidase 2
chr2_-_172675480 0.649 NM_004405
DLX2
distal-less homeobox 2
chr1_-_181654027 0.641


chr1_-_233879617 0.637 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr12_+_52665196 0.629 NM_017409
HOXC10
homeobox C10
chr10_+_94823636 0.624 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr18_+_13208777 0.618 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr12_+_48641545 0.615 NM_001651
AQP5
aquaporin 5
chr2_-_192767494 0.605 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr14_+_102458745 0.598 NM_030943
AMN
amnionless homolog (mouse)
chr8_+_54015020 0.593 NM_005285
NPBWR1
neuropeptides B/W receptor 1
chr17_-_13445942 0.578 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr10_-_118022965 0.575 NM_005264
GFRA1
GDNF family receptor alpha 1
chr3_+_148609841 0.571 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr19_+_10261646 0.568 NM_003259
ICAM5
intercellular adhesion molecule 5, telencephalin
chr14_-_94306104 0.568 NM_173849
GSC
goosecoid homeobox
chrX_+_117992603 0.559 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr14_+_100362236 0.541 MEG3
maternally expressed 3 (non-protein coding)
chr7_-_37923040 0.540 NM_003014
SFRP4
secreted frizzled-related protein 4
chr1_-_114497994 0.537 NM_205848
SYT6
synaptotagmin VI
chr7_-_37922902 0.526 SFRP4
secreted frizzled-related protein 4
chr2_-_182253457 0.522 NM_002500
NEUROD1
neurogenic differentiation 1
chr12_+_52680143 0.518 NM_006897
HOXC9
homeobox C9
chr20_-_4177519 0.516 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr11_+_68208583 0.515 GAL
galanin prepropeptide
chr11_+_68208554 0.514 NM_015973
GAL
galanin prepropeptide
chr7_+_154943466 0.511 NM_001427
EN2
engrailed homeobox 2
chr5_+_80292313 0.509 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chrX_+_152565849 0.502 DUSP9
dual specificity phosphatase 9
chr10_+_24023680 0.495 NM_001098500
KIAA1217
KIAA1217
chr15_+_39739864 0.490 NM_001080541
NM_001164273
MGA

MAX gene associated

chr2_+_26249463 0.489 NM_001168241
FAM59B
family with sequence similarity 59, member B
chr17_-_32368033 0.486


chr11_+_108798084 0.482 C11orf87
chromosome 11 open reading frame 87
chr5_-_95794416 0.478 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr11_+_65311142 0.476 OVOL1
ovo-like 1(Drosophila)
chr5_-_37875538 0.474 NM_000514
GDNF
glial cell derived neurotrophic factor
chr5_+_80292213 0.472 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr6_+_101953581 0.471 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr8_-_24869945 0.468 NM_006158
NEFL
neurofilament, light polypeptide
chr10_-_62373828 0.467 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr15_+_39739933 0.463 MGA
MAX gene associated
chr10_-_64246129 0.459 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr2_-_96899396 0.458 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr12_+_4788602 0.455 NM_002235
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr11_+_65311104 0.454 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr6_-_84475424 0.454 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr16_-_52877868 0.451 NM_024336
IRX3
iroquois homeobox 3
chr19_-_17660005 0.450 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr3_+_32834513 0.450 NM_001039111
TRIM71
tripartite motif containing 71
chr2_-_172675873 0.448 DLX2
distal-less homeobox 2
chr7_-_100595552 0.444 NM_003378
VGF
VGF nerve growth factor inducible
chr1_-_181654124 0.442 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr6_+_101953389 0.441 GRIK2
glutamate receptor, ionotropic, kainate 2
chr10_-_88116181 0.438 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr11_+_125279481 0.435 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chrX_-_18282698 0.429 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr12_-_112394259 0.426 NM_022363
LHX5
LIM homeobox 5
chrX_+_21302317 0.420 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chrX_+_117992623 0.419 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chrX_-_138114817 0.415 FGF13
fibroblast growth factor 13
chr16_-_52877829 0.404 IRX3
iroquois homeobox 3
chr16_-_65742323 0.400 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr7_-_98305599 0.399 NM_001134450
NM_001134451
NM_152913
TMEM130


transmembrane protein 130


chr6_+_1336077 0.399


chr20_+_21634515 0.399 PAX1
paired box 1
chr2_-_192767844 0.395 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr12_+_52634950 0.395 NM_173860
HOXC12
homeobox C12
chr1_-_37272295 0.393 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr12_+_70120028 0.391 NM_003667
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr10_-_7491204 0.389 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr9_+_86474500 0.387 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr7_-_98305551 0.384 TMEM130
transmembrane protein 130
chr13_+_24940965 0.381 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr22_+_37193961 0.377 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr19_-_62912347 0.375 NM_001085384
ZNF154
zinc finger protein 154
chr1_+_4614528 0.373 AJAP1
adherens junctions associated protein 1
chr19_-_52710129 0.372 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr15_-_66511488 0.371 NM_001004439
ITGA11
integrin, alpha 11
chr1_+_63561632 0.367 FOXD3
forkhead box D3
chr1_+_110494654 0.367 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr10_-_128067062 0.367 NM_003474
NM_021641
ADAM12

ADAM metallopeptidase domain 12

chr10_-_120830301 0.367 NM_003750
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr9_+_86474457 0.366 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr2_+_176680251 0.365 NM_021192
HOXD11
homeobox D11
chr4_+_166519392 0.361 NM_001873
CPE
carboxypeptidase E
chr22_-_45037882 0.360 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr19_+_10388448 0.359 PDE4A
phosphodiesterase 4A, cAMP-specific
chrX_-_101297417 0.359 NM_001159560
NM_001012978
BEX5

brain expressed, X-linked 5

chr6_-_137857213 0.358 NM_175747
OLIG3
oligodendrocyte transcription factor 3
chr9_+_86474553 0.358 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_117903682 0.356 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr15_-_77169894 0.355 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr13_+_24940917 0.354 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr17_-_7138590 0.353 NM_015982
YBX2
Y box binding protein 2
chr13_-_94162249 0.352 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr1_+_41022066 0.352 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr17_-_7138535 0.350 YBX2
Y box binding protein 2
chr16_-_27982277 0.347 NM_001109763
GSG1L
GSG1-like
chr1_+_155097230 0.346 NM_001012331
NM_002529
NTRK1

neurotrophic tyrosine kinase, receptor, type 1

chr19_+_55398680 0.341 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr9_+_86474393 0.340 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr17_-_7138620 0.338 YBX2
Y box binding protein 2
chr17_-_77824849 0.338 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr19_+_54558798 0.335 NM_001197302
NM_001197301
NM_014419
DKKL1


dickkopf-like 1


chr7_+_5598964 0.334 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr8_+_120289735 0.334 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_-_27195276 0.327 NM_001166239
CGREF1
cell growth regulator with EF-hand domain 1
chr16_-_3008162 0.325 NM_021195
CLDN6
claudin 6
chr5_+_170779264 0.322 NM_003862
FGF18
fibroblast growth factor 18
chr20_-_60484420 0.322 NM_080473
GATA5
GATA binding protein 5
chr6_-_119441045 0.320 FAM184A
family with sequence similarity 184, member A
chr20_+_32610161 0.319 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr5_-_146238336 0.318 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr10_-_64246080 0.317 EGR2
early growth response 2
chr9_+_86474445 0.317 NM_001007097
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr17_+_7151653 0.317 EIF5A
eukaryotic translation initiation factor 5A
chr10_-_120830286 0.316 EIF3A
eukaryotic translation initiation factor 3, subunit A
chr5_-_131591380 0.314 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr19_+_54723044 0.312 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr3_+_185580554 0.310 NM_003741
CHRD
chordin
chr13_-_35818603 0.309 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr1_+_29435534 0.306 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr7_+_100041143 0.303 PCOLCE
procollagen C-endopeptidase enhancer
chr11_-_57173823 0.301 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr2_-_27195401 0.300 NM_001166240
NM_006569
CGREF1

cell growth regulator with EF-hand domain 1

chr1_+_26368969 0.299 NM_015871
ZNF593
zinc finger protein 593
chr11_-_59139755 0.298 OSBP
oxysterol binding protein
chr9_-_78710698 0.296 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr19_-_52709975 0.296 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr19_+_5632016 0.295 NM_198704
NM_198705
NM_198533
NM_198707
NM_198706
NM_198708
HSD11B1L





hydroxysteroid (11-beta) dehydrogenase 1-like





chr14_+_71468902 0.295 RGS6
regulator of G-protein signaling 6
chr6_-_33494042 0.293 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr7_-_98305419 0.292 TMEM130
transmembrane protein 130
chr14_+_67156386 0.291 ARG2
arginase, type II
chr5_-_1935764 0.289 NM_016358
IRX4
iroquois homeobox 4
chr3_-_73756668 0.289 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr12_-_131415854 0.287 NM_001122636
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr14_+_67156405 0.285 ARG2
arginase, type II
chr12_-_112058403 0.285 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr19_+_10673105 0.285 NM_031209
QTRT1
queuine tRNA-ribosyltransferase 1
chr19_+_54149963 0.280 BAX
BCL2-associated X protein
chr19_-_52710089 0.279 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr12_+_6768960 0.278 CD4
CD4 molecule
chr10_-_128067052 0.278 ADAM12
ADAM metallopeptidase domain 12
chr17_-_37828643 0.275 NM_012232
PTRF
polymerase I and transcript release factor
chr12_+_110935612 0.274


chr4_-_44145580 0.273 NM_198353
KCTD8
potassium channel tetramerisation domain containing 8
chr9_-_98421894 0.272 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr1_+_109810622 0.271 NM_001040709
SYPL2
synaptophysin-like 2
chr12_+_6768934 0.271 NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4



CD4 molecule



chr1_-_62557655 0.270 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr1_+_15123165 0.268 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr4_-_164473107 0.267 NM_000909
NPY1R
neuropeptide Y receptor Y1
chrX_-_13866565 0.267 NM_001001994
GPM6B
glycoprotein M6B
chr13_-_35818777 0.266 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr17_-_44058612 0.266 NM_024017
HOXB9
homeobox B9
chr22_-_29833484 0.265 NM_080430
SELM
selenoprotein M
chr14_+_92721048 0.264 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr14_-_22458134 0.263 RBM23
RNA binding motif protein 23
chr7_+_5598979 0.262 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr9_-_89779413 0.262 NM_001039803
NM_001170639
NM_001170640
NM_012119
NM_178432
CDK20




cyclin-dependent kinase 20




chr9_-_103289154 0.262 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr19_+_55045754 0.259 PTOV1
prostate tumor overexpressed 1
chr19_+_54149941 0.257 BAX
BCL2-associated X protein
chr17_-_35017650 0.256 NEUROD2
neurogenic differentiation 2
chr20_-_22512893 0.255 FOXA2
forkhead box A2
chr3_+_127118130 0.254 LOC100125556
family with sequence similarity 86, member A pseudogene

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.