Motif ID: CREB1.p2

Z-value: 2.561


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1



Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_32755778 6.700 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_-_128285136 4.299 WDR33
WD repeat domain 33
chr2_-_128285214 3.929 NM_001006622
NM_001006623
NM_018383
WDR33


WD repeat domain 33


chr1_+_119484529 3.889


chr13_+_48720047 3.836 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr7_-_19715127 3.251 NM_001002926
TWISTNB
TWIST neighbor
chr1_+_169721260 3.229 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr2_-_43676603 3.206 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr5_-_172130766 3.194 NM_004417
DUSP1
dual specificity phosphatase 1
chr2_+_192251105 2.832 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr5_-_133332173 2.660 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr16_+_18986459 2.655 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_126319540 2.568 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr14_+_34521945 2.557 SRP54
signal recognition particle 54kDa
chr2_-_179051471 2.536 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr2_+_95432150 2.439 NM_016044
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr5_+_148186348 2.366 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr16_-_3707450 2.364 NM_016292
TRAP1
TNF receptor-associated protein 1
chr20_+_36810510 2.352 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr2_+_219453487 2.339 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr17_-_35337288 2.337 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr20_-_5048443 2.309 NM_182649
PCNA
proliferating cell nuclear antigen
chr20_+_3749164 2.298 NM_018347
C20orf29
chromosome 20 open reading frame 29
chr14_+_59628381 2.279 NM_022495
C14orf135
chromosome 14 open reading frame 135
chr6_-_26393705 2.261 NM_003543
HIST1H4H
histone cluster 1, H4h
chr4_-_120595218 2.251


chr1_+_36462625 2.238 THRAP3
thyroid hormone receptor associated protein 3
chr6_-_3102690 2.237 NM_001069
TUBB2A
tubulin, beta 2A
chr1_-_119484733 2.230 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr3_-_101077605 2.192 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr4_-_170770111 2.171 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr14_+_34521854 2.164 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr7_-_140270749 2.151 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr2_-_202353898 2.149 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr12_-_10657397 2.144 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr17_+_44325127 2.142 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr20_+_51023159 2.139 TSHZ2
teashirt zinc finger homeobox 2
chr17_-_46298671 2.135 TOB1
transducer of ERBB2, 1
chr16_+_18986417 2.134 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_-_54051290 2.119 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr12_+_105692466 2.112 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr3_+_186483408 2.098 LOC100505749
MAP3K13
hypothetical LOC100505749
mitogen-activated protein kinase kinase kinase 13
chr6_+_26312758 2.094 NM_003545
HIST1H4E
histone cluster 1, H4e
chr2_-_234317362 2.067 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr11_-_124871258 2.045 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr16_+_18986721 2.037 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr1_+_149247519 1.975 NM_021222
PRUNE
prune homolog (Drosophila)
chr6_-_30289092 1.954 NM_003449
TRIM26
tripartite motif containing 26
chr4_-_148824585 1.954 NM_138364
PRMT10
protein arginine methyltransferase 10 (putative)
chr6_-_34772565 1.932 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr1_+_232575850 1.905 NM_001012985
C1orf31
chromosome 1 open reading frame 31
chr3_+_101462375 1.903 NM_018309
TBC1D23
TBC1 domain family, member 23
chr17_-_68819713 1.900 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr6_-_17814596 1.897 NM_005124
NUP153
nucleoporin 153kDa
chr6_+_89848229 1.896 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_38715567 1.892 BTBD9
BTB (POZ) domain containing 9
chr17_-_39556483 1.886 HDAC5
histone deacetylase 5
chr20_-_5539487 1.883 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr6_-_34772495 1.882 C6orf106
chromosome 6 open reading frame 106
chr5_-_89861048 1.875 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr1_-_159413833 1.861 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr19_-_10202947 1.850 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr2_+_108769572 1.838 NM_144978
CCDC138
coiled-coil domain containing 138
chr16_+_68938264 1.837 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr6_+_116798791 1.827 NM_013352
DSE
dermatan sulfate epimerase
chr17_-_39556535 1.822 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr17_+_25828546 1.800 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr3_+_171558188 1.783 SKIL
SKI-like oncogene
chr17_-_8092078 1.770 CTC1
CTS telomere maintenance complex component 1
chr3_+_12573513 1.769 NM_014160
MKRN2
makorin ring finger protein 2
chr16_-_47201588 1.766 NM_153029
N4BP1
NEDD4 binding protein 1
chr16_-_85146181 1.756 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr8_+_17148755 1.752 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr19_-_52308848 1.734 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr4_+_144654526 1.730


chr6_-_15356865 1.724


chr3_+_171558215 1.724 SKIL
SKI-like oncogene
chr3_+_158026769 1.684 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr9_-_168913 1.684 NM_001145355
NM_001145356
NM_018491
CBWD2
CBWD1


COBW domain containing 2
COBW domain containing 1


chr20_+_254205 1.660 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr4_+_144654005 1.654 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr3_+_151608673 1.653 TSC22D2
TSC22 domain family, member 2
chr2_-_68332985 1.642 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr20_+_30161173 1.639 TM9SF4
transmembrane 9 superfamily protein member 4
chr2_+_113911737 1.632 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr9_-_68552337 1.628 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr1_+_70649451 1.627 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr20_-_48163071 1.627 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr21_-_29286982 1.596 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr10_+_112247614 1.596 NM_004419
DUSP5
dual specificity phosphatase 5
chr15_-_58558410 1.585 NM_001018089
NM_024611
NARG2

NMDA receptor regulated 2

chr17_+_15843832 1.579 TTC19
tetratricopeptide repeat domain 19
chr2_-_202354139 1.579 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr2_-_202353818 1.575


chr6_-_27222556 1.573 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr15_-_49817090 1.562 LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_+_74539039 1.561 NM_012477
WBP1
WW domain binding protein 1
chr4_-_104338924 1.556 NM_001813
CENPE
centromere protein E, 312kDa
chr9_+_70046658 1.554 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr3_+_52694975 1.534 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr1_-_36636044 1.531 NM_032881
LSM10
LSM10, U7 small nuclear RNA associated
chr2_-_27566024 1.530 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr1_+_161027115 1.509 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr9_-_93917458 1.508 NM_006415
NM_178324
SPTLC1

serine palmitoyltransferase, long chain base subunit 1

chr16_+_29880842 1.506 NM_001083613
NM_194280
TMEM219

transmembrane protein 219

chr4_-_186584031 1.486 NM_018359
UFSP2
UFM1-specific peptidase 2
chr16_-_11744103 1.481 NM_015914
TXNDC11
thioredoxin domain containing 11
chr2_+_105727836 1.480 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr1_+_40399642 1.476 RLF
rearranged L-myc fusion
chr12_-_56111054 1.474 R3HDM2
R3H domain containing 2
chr6_+_49539049 1.474 NM_018132
CENPQ
centromere protein Q
chr17_-_50854054 1.468 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr3_-_102888090 1.464 NM_000986
RPL24
ribosomal protein L24
chr14_+_101855836 1.462 NM_018335
ZNF839
zinc finger protein 839
chr10_+_85889164 1.460 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr15_+_70553743 1.452 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr14_-_23781607 1.449 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr11_-_66367279 1.444


chr19_-_9510257 1.442 NM_024106
ZNF426
zinc finger protein 426
chr3_-_122951200 1.438 NM_004487
GOLGB1
golgin B1
chr19_+_40183169 1.437 GRAMD1A
GRAM domain containing 1A
chr6_-_38715613 1.437 BTBD9
BTB (POZ) domain containing 9
chr20_+_57948803 1.426 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr7_+_127015650 1.424 NM_001662
ARF5
ADP-ribosylation factor 5
chr4_+_153676857 1.424 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr3_+_186786655 1.424 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_-_149247464 1.409 NM_001163258
NM_018379
FAM63A

family with sequence similarity 63, member A

chr16_+_70437394 1.409 NM_001137675
ATXN1L
ataxin 1-like
chr17_-_34235078 1.405 NM_017748
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr8_+_128875902 1.405 PVT1
Pvt1 oncogene (non-protein coding)
chr16_+_15950707 1.401 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chr9_+_101623957 1.378 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr16_+_20819488 1.343 NM_001128301
NM_001128302
LYRM1

LYR motif containing 1

chr2_-_156897286 1.342 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_+_55219052 1.336 NM_182532
TMEM61
transmembrane protein 61
chr15_-_53487748 1.333 NM_004748
NM_020739
CCPG1

cell cycle progression 1

chr6_+_35335278 1.321 ZNF76
zinc finger protein 76
chr2_-_202215593 1.296 NM_152388
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr8_-_95343716 1.296 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr2_+_170149348 1.293 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_+_43303005 1.292 NM_001100594
NM_017719
SNRK

SNF related kinase

chr9_+_132990834 1.286 NUP214
nucleoporin 214kDa
chr9_-_6005602 1.283 NM_012416
RANBP6
RAN binding protein 6
chr16_+_66855827 1.279 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (cationic amino acid transporter, y+ system), member 6

chr1_+_40399618 1.279 NM_012421
RLF
rearranged L-myc fusion
chr16_-_72959492 1.279 LOC283922
pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr12_-_56452144 1.278 NM_005371
NM_023033
METTL1

methyltransferase like 1

chr2_-_144806498 1.266 GTDC1
glycosyltransferase-like domain containing 1
chr2_+_190014403 1.264 NM_032168
WDR75
WD repeat domain 75
chr6_-_30136734 1.256 ZNRD1-AS1
ZNRD1 antisense RNA 1 (non-protein coding)
chr1_+_32443822 1.253 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr6_+_30137014 1.252 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr3_+_150330060 1.244 NM_032383
HPS3
Hermansky-Pudlak syndrome 3
chr2_-_144806508 1.243 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr1_-_58938323 1.241 NM_001085487
MYSM1
Myb-like, SWIRM and MPN domains 1
chr16_-_83602587 1.238 ZDHHC7
zinc finger, DHHC-type containing 7
chr2_+_30523586 1.237 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr9_+_124066973 1.232 MRRF
mitochondrial ribosome recycling factor
chr15_+_48503860 1.223 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr17_-_45110339 1.216 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr11_-_62363551 1.216 WDR74
WD repeat domain 74
chr15_+_36533595 1.211 NM_001042429
NM_173611
FAM98B

family with sequence similarity 98, member B

chr2_-_25047988 1.209 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr19_-_52426055 1.199 NM_014417
BBC3
BCL2 binding component 3
chr16_-_20819061 1.199 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr20_-_34835546 1.197 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr20_-_25625173 1.186 NM_015655
ZNF337
zinc finger protein 337
chr17_-_632135 1.185 NM_016080
GLOD4
glyoxalase domain containing 4
chr12_+_70519753 1.184 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr2_-_240613357 1.182 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr17_-_46553083 1.180 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr10_+_21863099 1.174 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr17_+_33761234 1.174 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr6_+_35335212 1.172 ZNF76
zinc finger protein 76
chr1_-_35879619 1.171 PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr11_+_66952462 1.171 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr17_-_39447817 1.162 NM_032376
TMEM101
transmembrane protein 101
chr2_-_216944911 1.161 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr19_-_15351523 1.155 NM_005858
AKAP8
A kinase (PRKA) anchor protein 8
chr11_+_66367458 1.150 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr9_+_115023684 1.146 SLC31A1
solute carrier family 31 (copper transporters), member 1
chr8_-_95343696 1.145 GEM
GTP binding protein overexpressed in skeletal muscle
chr7_+_55987046 1.142 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr9_+_103200939 1.140 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr3_-_53356573 1.137 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr16_-_27187549 1.128 NSMCE1
non-SMC element 1 homolog (S. cerevisiae)
chr2_-_25048276 1.124 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr2_+_170149092 1.121 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr1_+_36462583 1.108 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr14_+_30161285 1.108 SCFD1
sec1 family domain containing 1
chr16_+_51722285 1.107 CHD9
chromodomain helicase DNA binding protein 9
chr3_+_171558143 1.099 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr3_+_102775716 1.098 NM_020357
PCNP
PEST proteolytic signal containing nuclear protein
chr20_+_1254033 1.098 LOC100507495
hypothetical LOC100507495
chr15_+_70553719 1.098 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr2_-_75280121 1.097 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr7_-_93471463 1.095 NM_005868
BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr1_+_226741665 1.094 NM_001010858
RNF187
ring finger protein 187
chr12_+_46133 1.091 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr18_+_11841388 1.079 NM_020412
CHMP1B
chromatin modifying protein 1B

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.35 2.44e-04 GO:0043231 intracellular membrane-bounded organelle
1.34 2.61e-04 GO:0043227 membrane-bounded organelle
2.07 1.11e-03 GO:0031981 nuclear lumen
1.93 1.94e-03 GO:0044428 nuclear part
1.90 2.13e-03 GO:0070013 intracellular organelle lumen
1.46 3.37e-03 GO:0044422 organelle part
1.87 3.50e-03 GO:0043233 organelle lumen
1.84 5.22e-03 GO:0031974 membrane-enclosed lumen
1.43 1.24e-02 GO:0044446 intracellular organelle part
1.43 1.33e-02 GO:0005634 nucleus
90.08 1.69e-02 GO:0035339 SPOTS complex
1.24 2.40e-02 GO:0043229 intracellular organelle
1.24 2.65e-02 GO:0043226 organelle
2.05 2.99e-02 GO:0005654 nucleoplasm

Nothing significant found in function category.