Motif ID: CRX.p2

Z-value: 2.508


Transcription factors associated with CRX.p2:

Gene SymbolEntrez IDGene Name
CRX 1406 cone-rod homeobox



Activity profile for motif CRX.p2.

activity profile for motif CRX.p2


Sorted Z-values histogram for motif CRX.p2

Sorted Z-values for motif CRX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CRX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_559618 7.453


chr1_+_559129 6.321


chr5_-_134290789 5.251


chr1_-_109957195 4.382 NM_005272
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr8_-_81155564 3.797 NM_001025252
TPD52
tumor protein D52
chr1_+_20269239 3.363 NM_000929
PLA2G5
phospholipase A2, group V
chr1_-_239865724 3.119 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr7_-_138014329 3.106 NM_001139456
SVOPL
SVOP-like
chr6_+_10693964 3.048 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_34020445 2.880 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chrX_+_135106578 2.823 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr22_+_21359175 2.796 IGLV3-25
immunoglobulin lambda variable 3-25
chr15_-_50270856 2.675 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr6_-_133120587 2.553 NM_004665
VNN2
vanin 2
chr4_+_187307320 2.433 NM_001006655
FAM149A
family with sequence similarity 149, member A
chr6_-_139654807 2.364 NM_153235
TXLNB
taxilin beta
chr9_-_111230926 2.330 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr8_-_18710575 2.225 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr16_-_3362283 2.222 NM_001190476
MTRNR2L4
MT-RNR2-like 4
chr9_+_132990760 2.178 NM_005085
NUP214
nucleoporin 214kDa
chr22_+_21094094 2.118


chr3_+_161877640 2.092 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr22_+_21370394 2.041 IGL@
immunoglobulin lambda locus
chr13_-_32658215 2.028 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_-_138935359 2.004 NM_020464
NHSL1
NHS-like 1
chr10_-_30958631 1.983 NM_183058
LYZL2
lysozyme-like 2
chr1_+_114323552 1.981 NM_020190
OLFML3
olfactomedin-like 3
chr1_+_226399026 1.973 NM_001159391
GUK1
guanylate kinase 1
chr1_+_22200735 1.949 NM_005747
CELA3A
chymotrypsin-like elastase family, member 3A
chr7_-_149960218 1.940 GIMAP6
GTPase, IMAP family member 6
chr16_+_79829794 1.894 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr8_-_7207899 1.844 NM_001164457
ZNF705G
zinc finger protein 705G
chr17_+_35718948 1.841 NM_000964
RARA
retinoic acid receptor, alpha
chr12_-_13139848 1.816 NM_031289
NM_153823
GSG1

germ cell associated 1

chr7_+_29486010 1.793 NM_001039936
CHN2
chimerin (chimaerin) 2
chr8_+_120955080 1.790 NM_022783
DEPTOR
DEP domain containing MTOR-interacting protein
chr1_+_201729893 1.781 NM_014359
OPTC
opticin
chr18_-_42810446 1.778 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr21_-_38792173 1.777 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr19_-_49725387 1.776 NM_001102597
NM_001102598
NM_001102599
NM_001102600
CEACAM20



carcinoembryonic antigen-related cell adhesion molecule 20



chr6_-_31007905 1.763 NM_205854
SFTA2
surfactant associated 2
chr20_-_43163021 1.744 NM_002251
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr11_+_111552298 1.688 NM_001037290
BCO2
beta-carotene oxygenase 2
chr6_-_149847809 1.687 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr7_+_93373755 1.680 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_7000349 1.652 NM_144614
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr1_+_165330710 1.626 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr6_+_163904564 1.614 QKI
quaking homolog, KH domain RNA binding (mouse)
chr17_-_36507900 1.613 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr22_+_21340757 1.595


chr7_+_128367961 1.594 NM_001098627
IRF5
interferon regulatory factor 5
chr18_-_42804531 1.588 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr1_-_171441234 1.586 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_+_108690199 1.563 C12orf34
chromosome 12 open reading frame 34
chr3_-_69254226 1.542 NM_198271
LMOD3
leiomodin 3 (fetal)
chr6_-_24597717 1.540 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr1_+_154386358 1.528 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_24985432 1.527 NM_015864
FAM65B
family with sequence similarity 65, member B
chr8_+_124032830 1.498 ZHX2
zinc fingers and homeoboxes 2
chr2_-_29150630 1.495 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr6_-_33862690 1.494 NM_001143944
LEMD2
LEM domain containing 2
chr1_+_158352143 1.463 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_-_12831164 1.454 NM_001013631
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr19_+_53016910 1.450 NM_000554
CRX
cone-rod homeobox
chr1_-_166779825 1.445 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr12_-_51528983 1.430 NM_173352
KRT78
keratin 78
chr18_-_72820939 1.429 MBP
myelin basic protein
chr20_-_48165886 1.428 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr3_-_15538164 1.350 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr7_+_111850367 1.342 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr1_-_109201228 1.340 NM_152763
AKNAD1
AKNA domain containing 1
chr3_-_21767819 1.333 NM_024697
ZNF385D
zinc finger protein 385D
chr16_-_46823682 1.328 NM_033151
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr1_+_116744992 1.325 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr15_-_88023576 1.322 NM_001145311
NM_002666
PLIN1

perilipin 1

chr1_+_151209751 1.310 NM_173080
SPRR4
small proline-rich protein 4
chr2_-_65013070 1.300 LOC400958
hypothetical LOC400958
chr4_+_17125885 1.287 NM_001079827
CLRN2
clarin 2
chr20_+_19903778 1.280 RIN2
Ras and Rab interactor 2
chr8_-_28403652 1.278 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr6_+_158990982 1.264 NM_001009991
SYTL3
synaptotagmin-like 3
chr10_-_48010879 1.238 NM_002900
RBP3
retinol binding protein 3, interstitial
chr11_+_69176391 1.226 CCND1
cyclin D1
chr12_+_55201854 1.225 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr4_-_40631397 1.209 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr21_-_35174742 1.204 RUNX1
runt-related transcription factor 1
chr21_-_42060334 1.202 RIPK4
receptor-interacting serine-threonine kinase 4
chr7_-_47954561 1.192 NM_138295
PKD1L1
polycystic kidney disease 1 like 1
chr9_-_70345549 1.192 NM_153237
C9orf71
chromosome 9 open reading frame 71
chr1_-_204455269 1.189 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr1_-_7923464 1.188 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr4_+_76700281 1.177 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr21_+_38550739 1.164 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr3_-_47909001 1.161 MAP4
microtubule-associated protein 4
chr2_-_158008763 1.160 NM_004288
CYTIP
cytohesin 1 interacting protein
chr5_-_16795336 1.159 MYO10
myosin X
chr1_+_40977092 1.157 NFYC
nuclear transcription factor Y, gamma
chr12_-_51298599 1.155 NM_175068
KRT73
keratin 73
chr9_-_103237851 1.153 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr5_-_156705250 1.152 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr7_-_149960612 1.124 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr5_-_137099602 1.123 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr22_+_20899155 1.119


chr7_+_129720209 1.112 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chrX_+_69404879 1.109 NM_004312
ARR3
arrestin 3, retinal (X-arrestin)
chr17_-_52248248 1.109 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr6_+_32515596 1.106 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr18_+_606671 1.091 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr1_+_200775864 1.081 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr1_-_152845399 1.080 NM_001193495
ADAR
adenosine deaminase, RNA-specific
chr6_-_42798286 1.075 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr17_-_36113502 1.040 NM_019016
KRT24
keratin 24
chr2_+_101974737 1.039 NM_004633
IL1R2
interleukin 1 receptor, type II
chr17_-_36346240 1.036 KRT23
keratin 23 (histone deacetylase inducible)
chr2_-_74424041 1.036 NM_133478
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr17_-_36587965 1.035 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr6_-_25679197 1.027


chr7_+_129771865 1.022 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr10_-_61819493 1.017 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_-_32265489 1.012 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr3_+_125586241 1.012 KALRN
kalirin, RhoGEF kinase
chr10_-_85991177 1.009 NM_015613
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr18_+_13601664 1.005 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr13_-_23369124 1.004 NM_001007537
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr1_-_171442937 0.998 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_-_47464143 0.989 NM_015270
ADCY6
adenylate cyclase 6
chr4_-_47678187 0.987 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr22_+_21384862 0.980 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr4_-_52578542 0.980 NM_001024611
LRRC66
leucine rich repeat containing 66
chr13_+_97856148 0.979


chr10_-_14412813 0.978 NM_018027
FRMD4A
FERM domain containing 4A
chr1_-_201321999 0.974 NM_002479
MYOG
myogenin (myogenic factor 4)
chr22_+_21011653 0.964


chr11_+_7574992 0.963 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_123083096 0.956 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr18_+_27281729 0.955 NM_001944
DSG3
desmoglein 3
chr13_+_112746908 0.954 MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_+_142885087 0.953 NM_176883
TAS2R41
taste receptor, type 2, member 41
chr18_+_19947314 0.953 TTC39C
tetratricopeptide repeat domain 39C
chr3_-_47073910 0.948 SETD2
SET domain containing 2
chr2_-_202271598 0.946 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_151596953 0.942 NM_002965
S100A9
S100 calcium binding protein A9
chr1_-_21478571 0.940 NM_001113347
ECE1
endothelin converting enzyme 1
chr7_-_98643024 0.940 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr9_+_102380156 0.936 NM_001018116
MURC
muscle-related coiled-coil protein
chr15_+_57286313 0.935 NM_033195
LDHAL6B
lactate dehydrogenase A-like 6B
chr6_-_52217185 0.932 NM_052872
IL17F
interleukin 17F
chr2_+_38031099 0.929 NM_001170793
NM_144713
FAM82A1

family with sequence similarity 82, member A1

chr7_+_28497272 0.924 CREB5
cAMP responsive element binding protein 5
chr12_-_25597444 0.923 NM_152590
NM_001145728
NM_001145729
IFLTD1


intermediate filament tail domain containing 1


chr6_-_32447626 0.921 NM_006781
C6orf10
chromosome 6 open reading frame 10
chr17_-_36528113 0.916 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr17_-_44641741 0.916 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr21_+_38550533 0.914 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_1278469 0.910 NM_182632
SLC6A18
solute carrier family 6, member 18
chr5_+_36644187 0.909 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_8707368 0.908 NM_015210
KIAA0802
KIAA0802
chr3_+_115099007 0.908 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr7_+_142459538 0.907 NM_001001667
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr5_+_14541523 0.903 TRIO
triple functional domain (PTPRF interacting)
chr5_+_149977398 0.903 NM_001166209
SYNPO
synaptopodin
chr12_-_109842736 0.901 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr17_+_38306339 0.901 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chrX_+_135079461 0.892 NM_001167819
FHL1
four and a half LIM domains 1
chr11_+_113280727 0.892 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr2_+_113601608 0.888 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr4_-_15686838 0.885 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr9_-_103397023 0.884 NM_147180
PPP3R2
protein phosphatase 3, regulatory subunit B, beta
chr2_+_113601616 0.882 IL1RN
interleukin 1 receptor antagonist
chr4_+_56731117 0.872 NM_020722
KIAA1211
KIAA1211
chr3_+_11269384 0.871 NM_000861
HRH1
histamine receptor H1
chr19_-_59452869 0.868 NM_001081442
NM_001081443
NM_006840
LILRB5


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5


chr1_+_24755152 0.866 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr17_+_33867169 0.864 NM_020876
ARHGAP23
Rho GTPase activating protein 23
chr2_-_96311367 0.860 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr5_-_180099663 0.856 NM_001001657
OR2Y1
olfactory receptor, family 2, subfamily Y, member 1
chr10_-_62431203 0.854 RHOBTB1
Rho-related BTB domain containing 1
chr11_-_101292462 0.852 NM_178127
ANGPTL5
angiopoietin-like 5
chr10_+_21924265 0.849 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr9_+_115678365 0.847 NM_133374
ZNF618
zinc finger protein 618
chr8_-_42353719 0.845 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr7_+_141110365 0.843 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr4_+_40032146 0.843 NM_017581
CHRNA9
cholinergic receptor, nicotinic, alpha 9
chr7_+_116447499 0.840 ST7
suppression of tumorigenicity 7
chr12_-_51086330 0.835 NM_033033
KRT82
keratin 82
chr8_+_67568044 0.832 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr13_-_35327798 0.831 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr2_+_3683660 0.823 NM_018436
ALLC
allantoicase
chr19_-_60941551 0.821 NM_176820
NLRP9
NLR family, pyrin domain containing 9
chr3_-_187744808 0.809 NM_017541
CRYGS
crystallin, gamma S
chr19_-_56222593 0.807 NM_144947
KLK11
kallikrein-related peptidase 11
chr6_+_144654565 0.806 NM_007124
UTRN
utrophin
chr7_+_116447527 0.803 ST7
suppression of tumorigenicity 7
chr15_-_79453472 0.802 NM_001080532
TMC3
transmembrane channel-like 3
chr15_+_60838053 0.801 TLN2
talin 2
chr1_-_191422346 0.797 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_-_61703850 0.778


chr6_-_149847718 0.777 ZC3H12D
zinc finger CCCH-type containing 12D
chr17_-_36396778 0.773 NM_182497
KRT40
keratin 40
chr12_+_54316910 0.773 NM_206899
OR10P1
olfactory receptor, family 10, subfamily P, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
6.86 2.99e-03 GO:0050953 sensory perception of light stimulus

Nothing significant found in compartment category.

Nothing significant found in function category.