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Motif ID: EGR1..3.p2

Z-value: 2.179

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_809879	4.849	NM_006651	CPLX1	complexin 1
chr2_+_104838177	3.741	NM_006236	POU3F3	POU class 3 homeobox 3
chr20_-_60074237	3.135	NM_003185	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr18_+_53253775	3.114	NM_004852	ONECUT2	one cut homeobox 2
chr1_+_41022066	2.910	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr15_+_22644448	2.861
chr2_+_42128521	2.522	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr7_-_526005	2.427	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr7_-_525556	2.389		PDGFA	platelet-derived growth factor alpha polypeptide
chr7_+_55922623	2.304		ZNF713	zinc finger protein 713
chr16_+_1143241	2.281	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr2_+_10101081	2.045	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr3_-_185461768	2.018	NM_033259	CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_+_99389300	1.947	NM_005604	POU3F2	POU class 3 homeobox 2
chr1_+_38032045	1.909	NM_001031740 NM_001113482	MANEAL	mannosidase, endo-alpha-like
chr13_-_19633182	1.874	NM_021954	GJA3	gap junction protein, alpha 3, 46kDa
chr17_+_75366524	1.865	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr17_+_77582774	1.835	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr6_+_99389318	1.809		POU3F2	POU class 3 homeobox 2
chr20_-_61933012	1.787		ZBTB46	zinc finger and BTB domain containing 46
chr4_+_77391876	1.772	NM_001136570	FAM47E	family with sequence similarity 47, member E
chr11_+_359723	1.731	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr19_+_52215982	1.675	NM_002517	NPAS1	neuronal PAS domain protein 1
chr3_-_49882308	1.657	NM_024046	CAMKV	CaM kinase-like vesicle-associated
chr19_+_540849	1.631	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr14_-_60022487	1.600	NM_174978	C14orf39	chromosome 14 open reading frame 39
chr16_-_27982277	1.575	NM_001109763	GSG1L	GSG1-like
chr14_-_20636337	1.545		ZNF219	zinc finger protein 219
chr12_+_127317900	1.537	NM_001136103	TMEM132C	transmembrane protein 132C
chr10_-_128884411	1.530	NM_001039762	FAM196A	family with sequence similarity 196, member A
chr10_-_103525646	1.518	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr12_+_119632213	1.514	NM_001080533	UNC119B	unc-119 homolog B (C. elegans)
chr11_+_2422747	1.507	NM_000218	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1
chr3_+_12304332	1.502	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr5_-_59225377	1.483	NM_001104631	PDE4D	phosphodiesterase 4D, cAMP-specific
chr10_+_133850325	1.480	NM_006426	DPYSL4	dihydropyrimidinase-like 4
chr17_+_9489578	1.470	NM_153210	USP43	ubiquitin specific peptidase 43
chr22_+_48951286	1.458	NM_001160300 NM_052839	PANX2	pannexin 2
chr11_-_16992524	1.454	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr7_+_49783774	1.448	NM_198570	VWC2	von Willebrand factor C domain containing 2
chr19_+_1704661	1.416	NM_001080488	ONECUT3	one cut homeobox 3
chr17_+_14145051	1.413	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr10_-_64248932	1.397	NM_001136178	EGR2	early growth response 2
chr6_+_19945578	1.373	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr10_+_134893766	1.317	NM_003577	UTF1	undifferentiated embryonic cell transcription factor 1
chr22_+_49459935	1.306	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr3_-_24511456	1.287		THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr22_+_28446288	1.275	NM_182527	CABP7	calcium binding protein 7
chr4_+_152549776	1.271	NM_001109977	FAM160A1	family with sequence similarity 160, member A1
chr16_+_86193993	1.267	NM_020655	JPH3	junctophilin 3
chr19_+_56506907	1.256	NM_001101372	IGLON5	IgLON family member 5
chr7_-_44331544	1.250	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr15_+_38520594	1.239	NM_014952	BAHD1	bromo adjacent homology domain containing 1
chr4_+_995395	1.216		FGFRL1	fibroblast growth factor receptor-like 1
chr19_+_38979502	1.215	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr3_-_159306214	1.201
chr19_+_57492236	1.189	NM_144684	ZNF480	zinc finger protein 480
chr1_+_116181927	1.185		NHLH2	nescient helix loop helix 2
chr15_-_43267441	1.181		SHF	Src homology 2 domain containing F
chr13_-_37341859	1.178	NM_001135955 NM_001135956 NM_001135957 NM_001135958 NM_003306 NM_016179	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chr16_+_28741873	1.175		ATXN2L	ataxin 2-like
chr2_+_171280944	1.174		SP5	Sp5 transcription factor
chr14_+_101297887	1.165	NM_001161725 NM_001161726	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr12_+_48641545	1.154	NM_001651	AQP5	aquaporin 5
chr2_-_233501069	1.150	NM_001114090	NGEF	neuronal guanine nucleotide exchange factor
chr16_+_28741908	1.142	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr2_+_235525355	1.138	NM_014521	SH3BP4	SH3-domain binding protein 4
chr7_+_44110527	1.134		AEBP1	AE binding protein 1
chr5_+_76542461	1.121	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr2_-_182253457	1.109	NM_002500	NEUROD1	neurogenic differentiation 1
chrX_-_152592450	1.107		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr3_+_148610516	1.091		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr4_-_111763655	1.091	NM_000325	PITX2	paired-like homeodomain 2
chr3_+_53504070	1.082	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr3_-_159306532	1.078	NM_001163678 NM_003030 NM_006884	SHOX2	short stature homeobox 2
chrX_-_72215949	1.071	NM_001012977	PABPC1L2A PABPC1L2B	poly(A) binding protein, cytoplasmic 1-like 2A poly(A) binding protein, cytoplasmic 1-like 2B
chr7_-_32897934	1.051	NM_015483	KBTBD2	kelch repeat and BTB (POZ) domain containing 2
chr4_+_2031036	1.040	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr3_+_46898673	1.038	NM_001184744	PTH1R	parathyroid hormone 1 receptor
chr14_+_51850754	1.035	NM_000956	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa
chrX_-_152853402	1.034	NM_003491	NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr7_-_100331417	1.033	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr5_-_45731976	1.022	NM_021072	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr15_+_39573363	1.021	NM_002220	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A
chr14_-_20636909	1.017	NM_001101672	ZNF219	zinc finger protein 219
chr1_+_32992131	1.016
chr16_-_2186465	1.014	NM_020764	CASKIN1	CASK interacting protein 1
chr16_+_28741861	1.008		ATXN2L	ataxin 2-like
chr5_+_167889123	1.006
chr4_-_105631915	0.998	NM_025212	CXXC4	CXXC finger protein 4
chr1_-_240754620	0.996	NM_152666	PLD5	phospholipase D family, member 5
chrX_-_132376660	0.993	NM_001448	GPC4	glypican 4
chr16_-_53520208	0.984		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr22_+_27798887	0.982	NM_001039570 NM_032045	KREMEN1	kringle containing transmembrane protein 1
chr1_-_158306570	0.973	NM_002241	KCNJ10	potassium inwardly-rectifying channel, subfamily J, member 10
chr17_+_56831951	0.965	NM_005994	TBX2	T-box 2
chr14_+_104402626	0.965	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr3_+_53503626	0.959		CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr19_+_659766	0.952	NM_001040134 NM_002579	PALM	paralemmin
chr9_-_111300350	0.947	NM_001145368 NM_002829	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chrX_-_50230329	0.947	NM_001013742	DGKK	diacylglycerol kinase, kappa
chr7_+_45580704	0.942		ADCY1	adenylate cyclase 1 (brain)
chr11_-_1549719	0.939	NM_004420	DUSP8	dual specificity phosphatase 8
chr19_+_12810258	0.938	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr13_-_113066366	0.930	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr19_+_7834124	0.924		EVI5L	ecotropic viral integration site 5-like
chr12_+_50271283	0.920	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_152591936	0.916	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chrX_+_51092407	0.915		NUDT10	nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr16_+_1604641	0.913	NM_020825	CRAMP1L	Crm, cramped-like (Drosophila)
chr2_+_176680251	0.908	NM_021192	HOXD11	homeobox D11
chr14_-_20636568	0.903	NM_016423	ZNF219	zinc finger protein 219
chr4_+_3264509	0.903		RGS12	regulator of G-protein signaling 12
chrX_+_23262905	0.892	NM_173495	PTCHD1	patched domain containing 1
chr1_-_40027097	0.886		BMP8B	bone morphogenetic protein 8b
chr17_+_45993338	0.885	NM_018896 NM_198376 NM_198377 NM_198378 NM_198379 NM_198380 NM_198382 NM_198383 NM_198384 NM_198385 NM_198386 NM_198387 NM_198388 NM_198396 NM_198397	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit
chr18_-_68685789	0.884	NM_138966	NETO1	neuropilin (NRP) and tolloid (TLL)-like 1
chr7_+_45580606	0.881	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr19_-_1518875	0.880	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr5_-_148014282	0.875		HTR4	5-hydroxytryptamine (serotonin) receptor 4
chr2_-_200028977	0.871		SATB2	SATB homeobox 2
chr5_-_9599157	0.865	NM_003966	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr7_+_24290331	0.864	NM_000905	NPY	neuropeptide Y
chr4_-_41848874	0.864		BEND4	BEN domain containing 4
chr9_+_139892049	0.863	NM_000718	CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr6_-_94185780	0.861	NM_004440	EPHA7	EPH receptor A7
chr7_-_525336	0.860		PDGFA	platelet-derived growth factor alpha polypeptide
chr19_+_40325993	0.860	NM_022006	FXYD7	FXYD domain containing ion transport regulator 7
chrX_-_132377087	0.860		GPC4	glypican 4
chr7_-_27206249	0.860	NM_000522	HOXA13	homeobox A13
chr6_+_84799969	0.859	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr1_+_60053050	0.852	NM_015888	HOOK1	hook homolog 1 (Drosophila)
chr9_-_137938778	0.845	NM_015447	CAMSAP1	calmodulin regulated spectrin-associated protein 1
chr1_-_31154023	0.842	NM_014654	SDC3	syndecan 3
chr19_+_38485583	0.832		LOC80054	hypothetical LOC80054
chr1_-_6162669	0.828	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr5_+_149526533	0.827	NM_001804	CDX1	caudal type homeobox 1
chr13_-_26232777	0.822	NM_005288	GPR12	G protein-coupled receptor 12
chr20_-_47532585	0.822	NM_004975	KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1
chr22_+_20101661	0.818	NM_015094	HIC2	hypermethylated in cancer 2
chr8_-_72919161	0.815		MSC	musculin
chr10_-_132999798	0.813		TCERG1L	transcription elongation regulator 1-like
chr22_+_47350781	0.812	NM_015381	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr3_-_53054999	0.811		SFMBT1	Scm-like with four mbt domains 1
chr22_+_38720881	0.809	NM_138435	FAM83F	family with sequence similarity 83, member F
chrX_+_16874651	0.809	NM_001080975 NM_004726	REPS2	RALBP1 associated Eps domain containing 2
chr13_+_24844084	0.801	NM_016529	ATP8A2	ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr15_-_43267139	0.782		SHF	Src homology 2 domain containing F
chr20_-_538909	0.777	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr16_+_1323627	0.774		BAIAP3	BAI1-associated protein 3
chr5_-_45731588	0.773		HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr4_-_111763356	0.768		PITX2	paired-like homeodomain 2
chr5_+_3649167	0.763	NM_024337	IRX1	iroquois homeobox 1
chr11_+_56984702	0.760	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr12_+_52689062	0.756	NM_022658	HOXC8	homeobox C8
chr1_-_21850874	0.755	NM_001145658	RAP1GAP	RAP1 GTPase activating protein
chr19_-_13478037	0.755	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr16_-_695719	0.749	NM_153350	FBXL16	F-box and leucine-rich repeat protein 16
chr20_+_20296744	0.746	NM_002196	INSM1	insulinoma-associated 1
chr9_-_23811477	0.745	NM_001171197	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_96899396	0.741	NM_017789	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr14_+_20636935	0.740	NM_001146683	C14orf176	chromosome 14 open reading frame 176
chr8_-_144313053	0.733		LY6H	lymphocyte antigen 6 complex, locus H
chrX_-_152592958	0.733	NM_001039582	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr1_-_23623713	0.732	NM_003196	TCEA3	transcription elongation factor A (SII), 3
chr16_+_1143738	0.731		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chrX_+_17303270	0.730		NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr16_-_19803606	0.729	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr6_-_46566969	0.728		RCAN2	regulator of calcineurin 2
chr17_-_75427644	0.728	NM_003655	CBX4	chromobox homolog 4
chr7_+_6622051	0.727	NM_017560	ZNF853	zinc finger protein 853
chr11_-_94603857	0.727	NM_144665	SESN3	sestrin 3
chr13_-_113066202	0.726		GRTP1	growth hormone regulated TBC protein 1
chr4_-_41579325	0.726
chr15_-_27901828	0.722	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr8_-_26778832	0.721	NM_000680 NM_033302 NM_033303 NM_033304	ADRA1A	adrenergic, alpha-1A-, receptor
chr17_+_56832492	0.720		TBX2	T-box 2
chr17_+_26839143	0.718		RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr5_+_79366746	0.715	NM_003248	THBS4	thrombospondin 4
chr11_-_70641267	0.713		SHANK2	SH3 and multiple ankyrin repeat domains 2
chr8_-_144583718	0.713	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr8_+_16929116	0.712	NM_181723	EFHA2	EF-hand domain family, member A2
chr7_+_44110470	0.709	NM_001129	AEBP1	AE binding protein 1
chr9_+_70509925	0.707	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_+_56832255	0.703		TBX2	T-box 2
chr7_-_32897888	0.701		KBTBD2	kelch repeat and BTB (POZ) domain containing 2
chr13_+_111769913	0.698	NM_005986	SOX1	SRY (sex determining region Y)-box 1
chr15_-_81113676	0.690	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr8_-_75396016	0.690	NM_020647	JPH1	junctophilin 1
chr1_-_99242765	0.686	NM_001010861 NM_001037317	LPPR5	lipid phosphate phosphatase-related protein type 5
chr17_+_6620275	0.686	NM_153230	FBXO39	F-box protein 39
chr3_-_48675321	0.685	NM_001407	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr15_-_91433165	0.682	NM_020211	RGMA	RGM domain family, member A
chr14_-_62581656	0.679	NM_139318 NM_172375	KCNH5	potassium voltage-gated channel, subfamily H (eag-related), member 5
chr9_+_128416542	0.678	NM_001174146 NM_001174147 NM_002316	LMX1B	LIM homeobox transcription factor 1, beta
chr2_-_70871239	0.674	NM_001004311	FIGLA	folliculogenesis specific basic helix-loop-helix
chr20_-_30636535	0.674		LOC284804	hypothetical protein LOC284804
chr19_-_60383280	0.671	NM_003180	SYT5	synaptotagmin V
chr8_-_23619866	0.670	NM_001136271	NKX2-6	NK2 transcription factor related, locus 6 (Drosophila)
chr11_-_118740069	0.670	NM_171997	USP2	ubiquitin specific peptidase 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.77	7.30e-06	GO:0048731	system development
2.50	1.36e-05	GO:0007275	multicellular organismal development
3.23	3.75e-05	GO:0048513	organ development
2.49	9.42e-05	GO:0048856	anatomical structure development
2.28	1.48e-04	GO:0032502	developmental process
3.44	2.32e-04	GO:0007399	nervous system development
1.88	1.91e-03	GO:0032501	multicellular organismal process
2.56	7.53e-03	GO:0006355	regulation of transcription, DNA-dependent
3.62	9.26e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.41	1.18e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
3.75	1.33e-02	GO:0006351	transcription, DNA-dependent
2.46	1.37e-02	GO:0051252	regulation of RNA metabolic process
2.35	1.81e-02	GO:0010556	regulation of macromolecule biosynthetic process
2.28	1.89e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.28	1.89e-02	GO:0031326	regulation of cellular biosynthetic process
2.26	2.27e-02	GO:0009889	regulation of biosynthetic process
151.35	2.49e-02	GO:0021869	forebrain ventricular zone progenitor cell division
2.28	2.91e-02	GO:0010468	regulation of gene expression
2.49	3.05e-02	GO:0030154	cell differentiation
2.21	3.09e-02	GO:0051171	regulation of nitrogen compound metabolic process
3.38	3.84e-02	GO:0032774	RNA biosynthetic process
2.42	4.52e-02	GO:0048869	cellular developmental process
4.20	4.82e-02	GO:0009887	organ morphogenesis
3.53	4.94e-02	GO:0048699	generation of neurons

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
11.78	1.71e-04	GO:0034703	cation channel complex
7.65	2.91e-03	GO:0034702	ion channel complex
23.50	2.39e-02	GO:0034704	calcium channel complex
10.45	5.00e-02	GO:0008076	voltage-gated potassium channel complex
10.45	5.00e-02	GO:0034705	potassium channel complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.06	4.68e-05	GO:0030528	transcription regulator activity
6.27	1.10e-04	GO:0015267	channel activity
6.26	1.12e-04	GO:0022803	passive transmembrane transporter activity
3.90	1.88e-04	GO:0001071	nucleic acid binding transcription factor activity
3.90	1.88e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
11.20	2.71e-04	GO:0022843	voltage-gated cation channel activity
5.88	6.29e-04	GO:0022838	substrate-specific channel activity
8.51	1.66e-03	GO:0005244	voltage-gated ion channel activity
8.51	1.66e-03	GO:0022832	voltage-gated channel activity
6.89	1.85e-03	GO:0005261	cation channel activity
5.38	3.86e-03	GO:0005216	ion channel activity
6.05	4.71e-03	GO:0022836	gated channel activity
11.59	6.75e-03	GO:0005249	voltage-gated potassium channel activity
34.06	8.69e-03	GO:0004683	calmodulin-dependent protein kinase activity
9.02	2.21e-02	GO:0005267	potassium channel activity
2.20	2.71e-02	GO:0003677	DNA binding