Motif ID: EP300.p2

Z-value: 2.194


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300



Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_6808025 1.749 LEPREL2
leprecan-like 2
chr13_-_43259032 1.719 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr4_-_122213018 1.588 NM_024574
C4orf31
chromosome 4 open reading frame 31
chr4_+_172971149 1.558 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr1_-_29322993 1.545 NM_001003682
TMEM200B
transmembrane protein 200B
chr14_-_50480857 1.479 NM_001163940
NM_002863
PYGL

phosphorylase, glycogen, liver

chr9_-_129729518 1.398 NM_173492
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr9_+_70107602 1.386 NM_199135
FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr17_+_56843893 1.316 NM_203425
C17orf82
chromosome 17 open reading frame 82
chr17_+_69939130 1.304 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr20_+_43468046 1.265 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr2_-_230287442 1.161 NM_139072
DNER
delta/notch-like EGF repeat containing
chr7_-_117300763 1.148 NM_033427
CTTNBP2
cortactin binding protein 2
chr7_+_128257698 1.124 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr19_+_41039649 1.094 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr10_-_134449467 1.094 NM_177400
NKX6-2
NK6 homeobox 2
chr16_-_85099941 1.093 LOC400550
hypothetical LOC400550
chr21_+_44941514 1.080 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr4_+_183302105 1.069 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr22_-_27405708 1.045 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr19_+_12966970 1.037 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_+_114552871 1.021 NM_001012994
SNX30
sorting nexin family member 30
chr19_-_1352474 1.016 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr6_+_43151922 1.006 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr20_+_43468617 0.989 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr8_-_23077392 0.980 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr1_-_154913712 0.978 NM_006617
NES
nestin
chr3_-_127558747 0.973 NM_014079
KLF15
Kruppel-like factor 15
chrX_+_37093448 0.951 NM_000950
NM_001142395
NM_001173486
NM_001173489
NM_001173490
PRRG1




proline rich Gla (G-carboxyglutamic acid) 1




chr17_-_72045218 0.941 NM_134268
CYGB
cytoglobin
chr1_-_245342150 0.929 NM_207401
C1orf229
chromosome 1 open reading frame 229
chr6_+_99389300 0.927 NM_005604
POU3F2
POU class 3 homeobox 2
chr1_+_179148935 0.923 NM_020950
KIAA1614
KIAA1614
chr2_-_200030944 0.913 NM_001172509
SATB2
SATB homeobox 2
chr1_-_12599934 0.898 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr3_+_160964574 0.867 SCHIP1
schwannomin interacting protein 1
chr15_-_35177664 0.854 NM_172315
MEIS2
Meis homeobox 2
chr17_-_76985538 0.807


chr12_-_49853155 0.787 NM_001173452
NM_001173453
NM_005653
TFCP2


transcription factor CP2


chr2_-_204108151 0.778 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr1_+_56883333 0.775 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr12_-_26169074 0.770 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr9_+_2612052 0.758 VLDLR
very low density lipoprotein receptor
chr21_+_37300732 0.757 NM_018962
DSCR6
Down syndrome critical region gene 6
chr8_-_134378630 0.745 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr8_-_111056099 0.742 NM_014379
KCNV1
potassium channel, subfamily V, member 1
chr15_+_90738108 0.741 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chrX_+_71047344 0.735 NM_001013627
NHSL2
NHS-like 2
chr14_-_60260211 0.732 NM_017420
SIX4
SIX homeobox 4
chr3_+_35656012 0.731 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr14_+_92049396 0.730 NM_024832
RIN3
Ras and Rab interactor 3
chr11_-_103540233 0.725 NM_025208
NM_033135
PDGFD

platelet derived growth factor D

chr20_-_61755145 0.723 NM_015894
STMN3
stathmin-like 3
chr12_-_56445653 0.722 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr2_+_191818124 0.713 NM_001130158
NM_012223
NM_001161819
MYO1B


myosin IB


chr20_-_26137755 0.701 LOC284801
hypothetical protein LOC284801
chr4_-_159863889 0.698 NM_005038
PPID
peptidylprolyl isomerase D
chr19_-_51608665 0.697 NM_032040
CCDC8
coiled-coil domain containing 8
chr2_+_20729904 0.690 NM_182828
GDF7
growth differentiation factor 7
chr12_+_6179736 0.685 NM_001769
CD9
CD9 molecule
chr11_+_131286513 0.685 NTM
neurotrimin
chr3_-_130807865 0.682 NM_015103
PLXND1
plexin D1
chr11_+_104986009 0.670 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4


chr13_-_37341859 0.668 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr18_+_32021418 0.665 NM_017947
MOCOS
molybdenum cofactor sulfurase
chr9_-_108416 0.665 NM_207305
FOXD4
forkhead box D4
chr22_+_39404940 0.662 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr1_+_154878344 0.655 NM_021948
NM_198427
BCAN

brevican

chr11_+_104986620 0.651 NM_001112812
GRIA4
glutamate receptor, ionotrophic, AMPA 4
chr5_-_139992621 0.649 NM_000591
CD14
CD14 molecule
chr20_-_61108831 0.646 NM_080606
BHLHE23
basic helix-loop-helix family, member e23
chr9_-_132804057 0.642 NM_032843
FIBCD1
fibrinogen C domain containing 1
chr9_-_113977285 0.640 NM_022486
SUSD1
sushi domain containing 1
chr16_-_10183616 0.626 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr15_-_80123935 0.618 MEX3B
mex-3 homolog B (C. elegans)
chr11_+_696607 0.616 EPS8L2
EPS8-like 2
chr1_+_41022066 0.615 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr3_+_156280539 0.615 MME
membrane metallo-endopeptidase
chr1_-_94779727 0.612 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr8_+_106400322 0.611 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr19_-_60573552 0.608 NM_000641
IL11
interleukin 11
chr5_-_131658838 0.608


chr6_-_72187168 0.600 C6orf155
chromosome 6 open reading frame 155
chr8_-_122722674 0.599 NM_005328
HAS2
hyaluronan synthase 2
chr10_+_52504239 0.597 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr11_+_68208583 0.594 GAL
galanin prepropeptide
chr11_-_103539895 0.592 PDGFD
platelet derived growth factor D
chr3_-_186353421 0.589 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr20_-_4177519 0.578 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr5_-_114533448 0.576 TRIM36
tripartite motif containing 36
chr14_+_101297887 0.576 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr11_-_64267037 0.569 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_129823667 0.569 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr20_+_3000838 0.568 OXT
oxytocin, prepropeptide
chr10_-_125843092 0.568 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr11_-_103540275 0.567 PDGFD
platelet derived growth factor D
chr8_+_22465368 0.567 SORBS3
sorbin and SH3 domain containing 3
chr17_+_76988134 0.565 NM_001080519
BAHCC1
BAH domain and coiled-coil containing 1
chr5_+_42459568 0.563 NM_000163
GHR
growth hormone receptor
chr2_+_46378405 0.558 EPAS1
endothelial PAS domain protein 1
chr19_+_34709330 0.557 NM_001146339
VSTM2B
V-set and transmembrane domain containing 2B
chr3_+_112273352 0.556 PVRL3
poliovirus receptor-related 3
chr6_+_73388713 0.556 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr11_+_68208554 0.555 NM_015973
GAL
galanin prepropeptide
chr5_+_82803248 0.555 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr8_+_21971317 0.554 NM_001114135
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr18_+_53253775 0.554 NM_004852
ONECUT2
one cut homeobox 2
chr15_+_97010219 0.550 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr14_-_60260780 0.550 SIX4
SIX homeobox 4
chr19_+_447453 0.546 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr11_-_122571198 0.546 NM_024769
CLMP
CXADR-like membrane protein
chr17_-_1874927 0.544 NM_178568
RTN4RL1
reticulon 4 receptor-like 1
chr14_-_87859284 0.542 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr20_+_55569542 0.541 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr9_-_116920232 0.540 NM_002160
TNC
tenascin C
chr5_+_96024434 0.540 CAST
calpastatin
chr9_+_86473273 0.539 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr1_+_202308814 0.539 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr17_+_14145051 0.539 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr9_-_132804243 0.536 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr13_-_60887210 0.535 PCDH20
protocadherin 20
chr20_+_34143983 0.535 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr14_+_55654607 0.535 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr12_-_113328271 0.535 NM_181486
TBX5
T-box 5
chr2_+_130703384 0.531


chr19_-_15204767 0.531 NM_001142886
EPHX3
epoxide hydrolase 3
chr12_+_52665196 0.530 NM_017409
HOXC10
homeobox C10
chrX_+_1347692 0.528 NM_001161529
NM_001161531
NM_001161532
NM_006140
NM_172245
NM_172246
NM_172249
CSF2RA






colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)






chr1_+_219119358 0.523 NM_021958
HLX
H2.0-like homeobox
chr15_+_66658626 0.521 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr19_+_16157198 0.517 NM_014077
FAM32A
family with sequence similarity 32, member A
chr17_+_40089270 0.517 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr6_+_101948102 0.517


chr18_-_26935427 0.516 DSC2
desmocollin 2
chr2_+_200031333 0.515


chr12_-_53153639 0.511 NM_144594
GTSF1
gametocyte specific factor 1
chr2_+_109112428 0.510 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr20_-_22512893 0.509 FOXA2
forkhead box A2
chr1_-_182273114 0.507 GLT25D2
glycosyltransferase 25 domain containing 2
chr5_+_128823904 0.507 NM_133638
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr22_+_49386044 0.505 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr1_+_154351200 0.501 LMNA
lamin A/C
chr14_+_91859904 0.501 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr16_+_2461500 0.500 NM_006181
NTN3
netrin 3
chr11_-_64266916 0.498


chrX_-_99551926 0.498 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr1_+_155130146 0.497 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr14_-_106105805 0.493 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_19164973 0.487 NM_144633
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr19_-_40325194 0.487 LGI4
leucine-rich repeat LGI family, member 4
chr7_-_150605112 0.486 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr19_-_11390948 0.482 NM_001035223
NM_001161616
RGL3

ral guanine nucleotide dissociation stimulator-like 3

chr10_-_103991219 0.482 NM_005029
PITX3
paired-like homeodomain 3
chr18_-_26935883 0.482 NM_004949
NM_024422
DSC2

desmocollin 2

chr2_+_113973130 0.480 NM_012184
FOXD4L1
forkhead box D4-like 1
chr5_-_92942680 0.480 FLJ42709
hypothetical LOC441094
chr4_+_156900053 0.472 GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr1_+_213323182 0.470 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr22_+_36286350 0.470 NM_152243
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr18_+_65219114 0.467 NM_152721
DOK6
docking protein 6
chr12_+_54760153 0.467 NM_001005915
NM_001982
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr15_-_80125514 0.466 MEX3B
mex-3 homolog B (C. elegans)
chr11_-_72111027 0.465 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr1_-_176273680 0.464 LOC730102
quinone oxidoreductase-like protein 2 pseudogene
chr12_-_113606322 0.464 NM_005996
NM_016569
TBX3

T-box 3

chr14_+_55654900 0.463 PELI2
pellino homolog 2 (Drosophila)
chr1_-_13712744 0.463 NM_001010847
LRRC38
leucine rich repeat containing 38
chr1_+_26609893 0.463 LIN28A
lin-28 homolog A (C. elegans)
chr10_+_125415860 0.461 NM_153442
GPR26
G protein-coupled receptor 26
chr15_+_72695248 0.461 CLK3
CDC-like kinase 3
chr1_+_219119430 0.461 HLX
H2.0-like homeobox
chr11_+_10428443 0.461 NM_001172431
AMPD3
adenosine monophosphate deaminase 3
chr17_+_8865547 0.461 NM_004822
NTN1
netrin 1
chr19_+_50693570 0.460 NM_001080401
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr8_+_22465171 0.459 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr2_-_200028977 0.457 SATB2
SATB homeobox 2
chr19_-_18749728 0.455


chr1_-_225572419 0.454 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chr3_-_140148671 0.453 NM_023067
FOXL2
forkhead box L2
chr7_+_142262669 0.453 NM_004445
EPHB6
EPH receptor B6
chr6_+_73388291 0.449 NM_001160130
NM_001160132
NM_001160133
NM_001160134
NM_019842
KCNQ5




potassium voltage-gated channel, KQT-like subfamily, member 5




chr12_+_55896844 0.449 NM_007224
NXPH4
neurexophilin 4
chr10_-_95350949 0.448 NM_006744
RBP4
retinol binding protein 4, plasma
chr5_+_119827903 0.446 NM_016644
PRR16
proline rich 16
chr16_+_85158357 0.446 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr12_+_117903682 0.446 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr6_+_30082331 0.445 HLA-J
major histocompatibility complex, class I, J (pseudogene)
chr5_+_119827797 0.444 PRR16
proline rich 16
chr10_-_116154504 0.443 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr4_-_86106567 0.442 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr12_+_6363482 0.441 NM_002342
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr7_+_37926687 0.440 NM_017549
EPDR1
ependymin related protein 1 (zebrafish)
chr11_-_27678551 0.439 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chrX_+_67965517 0.437 NM_004429
EFNB1
ephrin-B1
chr2_+_182030173 0.436 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_+_156229934 0.435 KIRREL
kin of IRRE like (Drosophila)
chr10_-_116154212 0.435 AFAP1L2
actin filament associated protein 1-like 2
chr19_+_50535837 0.434 NM_177417
KLC3
kinesin light chain 3
chr9_+_139152595 0.433 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr10_+_102782156 0.431 SFXN3
sideroflexin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
34.70 1.04e-02 GO:0010001 glial cell differentiation
29.07 1.77e-02 GO:0042063 gliogenesis

Nothing significant found in compartment category.

Nothing significant found in function category.