Motif ID: ETS1,2.p2

Z-value: 2.079


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)



Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_15955719 2.121 FBLIM1
filamin binding LIM protein 1
chr8_+_22493928 1.817 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr21_-_45165302 1.526 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_24755152 1.492 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr21_-_45165249 1.460 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr12_-_121780835 1.257 NM_032554
GPR81
G protein-coupled receptor 81
chr6_+_10663934 1.215 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chrX_-_40480005 1.201 MED14
mediator complex subunit 14
chr11_-_46678715 1.153 ARHGAP1
Rho GTPase activating protein 1
chr19_-_61324412 1.140 ZNF787
zinc finger protein 787
chr10_+_71060008 1.136 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr11_-_46678691 1.118 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr21_-_45165204 1.103 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_46678736 1.098 ARHGAP1
Rho GTPase activating protein 1
chr9_-_132759045 1.092 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr18_+_13208777 1.085 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr18_+_21967813 1.051 NM_001025096
NM_001025097
NM_144662
PSMA8


proteasome (prosome, macropain) subunit, alpha type, 8


chr1_-_6468108 1.044 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr12_-_109372489 1.035 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr8_+_23016271 1.033 NM_003841
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr3_-_184756101 1.012 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr6_-_11490487 0.998 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr12_-_109372481 0.980 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr11_+_46678892 0.975 NM_024741
ZNF408
zinc finger protein 408
chr22_+_35586950 0.969 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr10_+_49562866 0.950 WDFY4
WDFY family member 4
chrX_-_40479718 0.929 NM_004229
MED14
mediator complex subunit 14
chr1_+_18680010 0.926 NM_152375
KLHDC7A
kelch domain containing 7A
chr19_+_17723285 0.925 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chrX_+_65152004 0.921


chr11_-_407324 0.908 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr19_+_63386193 0.905 NM_016324
NM_016325
NM_133502
ZNF274


zinc finger protein 274


chr12_-_109372517 0.902 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr1_-_119333701 0.896 NM_152380
TBX15
T-box 15
chr17_+_7549138 0.895 NM_001406
EFNB3
ephrin-B3
chr22_+_17337970 0.883 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr17_-_60208083 0.880 LOC146880
hypothetical LOC146880
chr11_+_2877486 0.869 NM_183233
SLC22A18
solute carrier family 22, member 18
chrX_-_40479893 0.868 MED14
mediator complex subunit 14
chr10_+_35934343 0.866 NM_153368
GJD4
gap junction protein, delta 4, 40.1kDa
chrX_-_73751185 0.852 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr8_-_146023228 0.844 LOC100130027
hypothetical LOC100130027
chr19_-_61324456 0.840 NM_001002836
ZNF787
zinc finger protein 787
chr12_-_56445653 0.837 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_+_31661934 0.823 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr12_-_109372543 0.823 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr17_+_4283967 0.816 NM_182538
SPNS3
spinster homolog 3 (Drosophila)
chr1_+_43386180 0.811 NM_001101376
FAM183A
family with sequence similarity 183, member A
chr10_+_129595289 0.809 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr12_-_109372462 0.805 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr1_-_6468600 0.803 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chrX_-_40479607 0.803 MED14
mediator complex subunit 14
chr17_+_4784097 0.797 RNF167
ring finger protein 167
chr12_-_6668787 0.795 NM_001039918
NM_133476
ZNF384

zinc finger protein 384

chr5_+_149360361 0.791 NM_014983
HMGXB3
HMG box domain containing 3
chrX_-_130792297 0.787 LOC286467
hypothetical LOC286467
chr1_+_22200735 0.780 NM_005747
CELA3A
chymotrypsin-like elastase family, member 3A
chr5_-_95774444 0.777 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chr14_-_93926679 0.770 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr12_-_6668680 0.769 ZNF384
zinc finger protein 384
chr1_+_22176004 0.762 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr1_-_31003260 0.761 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr8_+_38153223 0.759 NM_004874
BAG4
BCL2-associated athanogene 4
chr7_+_95239753 0.758 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr1_+_170077234 0.758 NM_001136127
NM_015569
DNM3

dynamin 3

chr14_+_68935133 0.756 NM_018375
SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr14_+_68935172 0.754 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr19_-_10166536 0.754 DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr10_-_72032519 0.752 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr3_-_173010921 0.750 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific

chr19_-_5802420 0.742 NM_000149
NM_001097639
NM_001097640
NM_001097641
FUT3



fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)



chr1_+_43539239 0.741 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr10_+_124020810 0.738 NM_144587
BTBD16
BTB (POZ) domain containing 16
chr1_+_38046055 0.732 NM_001142726
NM_198446
C1orf122

chromosome 1 open reading frame 122

chr4_+_2783743 0.728 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr1_+_28867801 0.728 NM_006582
NM_024482
GMEB1

glucocorticoid modulatory element binding protein 1

chr5_-_149360314 0.727 NM_030953
LOC728287
TIGD6
hypothetical protein LOC728287
tigger transposable element derived 6
chr15_+_76889873 0.722 MORF4L1
mortality factor 4 like 1
chr10_+_75174125 0.721 NM_004922
NM_198597
SEC24C

SEC24 family, member C (S. cerevisiae)

chr15_-_81743198 0.720 BNC1
basonuclin 1
chr15_+_55671393 0.719 NM_001018090
NM_001018091
NM_001018100
NM_152451
GCOM1



GRINL1A complex locus



chr1_+_38046404 0.718 C1orf122
chromosome 1 open reading frame 122
chr15_+_83160914 0.718 NM_020778
ALPK3
alpha-kinase 3
chr1_+_155130146 0.709 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr7_-_142816019 0.702 NM_005232
EPHA1
EPH receptor A1
chr1_-_199635057 0.701 LAD1
ladinin 1
chr3_+_47004457 0.697 NBEAL2
neurobeachin-like 2
chr10_-_72032447 0.692 PRF1
perforin 1 (pore forming protein)
chr1_-_199635339 0.691 LAD1
ladinin 1
chrX_-_67569894 0.682 NM_002547
OPHN1
oligophrenin 1
chr5_-_149304475 0.679 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr10_+_129595349 0.677 PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_+_75174151 0.677 SEC24C
SEC24 family, member C (S. cerevisiae)
chr12_-_6668880 0.669 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr1_+_38046005 0.665 C1orf122
chromosome 1 open reading frame 122
chr1_+_38046073 0.664 C1orf122
chromosome 1 open reading frame 122
chr17_-_4783943 0.663 NM_001165417
NM_001165418
NM_003562
SLC25A11


solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11


chr14_+_60045621 0.662 NM_007374
SIX6
SIX homeobox 6
chr22_-_35255216 0.660 NM_003753
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr4_-_153920326 0.653 NM_145720
TIGD4
tigger transposable element derived 4
chr19_-_4253389 0.652 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr3_-_124893875 0.644 MYLK
myosin light chain kinase
chr17_+_29606408 0.642 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr12_-_109372535 0.640 NM_005719
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr12_-_49853155 0.639 NM_001173452
NM_001173453
NM_005653
TFCP2


transcription factor CP2


chr11_+_46679140 0.637 NM_001184751
ZNF408
zinc finger protein 408
chr1_-_153213483 0.636 NM_001130041
NM_003029
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr12_-_108755565 0.633 TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr6_+_30212488 0.631 NM_138700
TRIM40
tripartite motif containing 40
chr1_+_150428404 0.630


chr1_-_181826086 0.628 NCF2
neutrophil cytosolic factor 2
chr9_-_137992967 0.626 NM_016172
UBAC1
UBA domain containing 1
chr4_+_153920382 0.624 NM_001025593
NM_001025595
NM_014447
ARFIP1


ADP-ribosylation factor interacting protein 1


chr22_+_20350272 0.620 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chrX_+_150316351 0.614 VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_-_199635240 0.612 NM_005558
LAD1
ladinin 1
chr11_+_36354110 0.612 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr16_+_65170851 0.611 NM_144673
CMTM2
CKLF-like MARVEL transmembrane domain containing 2
chr1_-_27159462 0.603 NM_152365
C1orf172
chromosome 1 open reading frame 172
chr5_+_149360480 0.602 HMGXB3
HMG box domain containing 3
chr13_-_27967215 0.601 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr22_+_22435207 0.601 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr1_-_240228987 0.601 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr1_-_38046270 0.595 YRDC
yrdC domain containing (E. coli)
chr20_+_30501108 0.595


chr3_+_187840842 0.595 NM_014375
FETUB
fetuin B
chrX_-_73751152 0.592


chr17_-_36347197 0.591 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr1_+_153213740 0.591 NM_001826
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr2_+_113648020 0.591 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chrX_-_73751155 0.591 RLIM
ring finger protein, LIM domain interacting
chr11_-_73856241 0.590 NM_005472
KCNE3
potassium voltage-gated channel, Isk-related family, member 3
chr3_+_46591048 0.589 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr7_+_6622051 0.588 NM_017560
ZNF853
zinc finger protein 853
chr7_-_99365178 0.587 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr8_-_133841988 0.586 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr19_-_10166600 0.586 DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr6_-_42270671 0.583 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr5_+_149360494 0.582 HMGXB3
HMG box domain containing 3
chr17_+_9489578 0.579 NM_153210
USP43
ubiquitin specific peptidase 43
chr11_+_112763722 0.578 NM_178510
ANKK1
ankyrin repeat and kinase domain containing 1
chr1_-_159306210 0.578 ARHGAP30
Rho GTPase activating protein 30
chr17_-_72151314 0.577 NM_018414
ST6GALNAC1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr17_-_4636248 0.576 NM_001144939
NM_001144940
NM_001144941
NM_182566
VMO1



vitelline membrane outer layer 1 homolog (chicken)



chr22_+_19543248 0.573 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chrX_-_73751135 0.572 RLIM
ring finger protein, LIM domain interacting
chrX_-_15783015 0.571 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr17_-_7106497 0.569 CLDN7
claudin 7
chrX_-_7855764 0.569 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr17_+_75366524 0.567 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr22_+_31526801 0.567 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr19_+_54530546 0.559 CD37
CD37 molecule
chr5_+_149360503 0.557 HMGXB3
HMG box domain containing 3
chr1_-_38046410 0.557 YRDC
yrdC domain containing (E. coli)
chr14_+_105024576 0.555 CRIP1
cysteine-rich protein 1 (intestinal)
chr13_+_23723831 0.553 SPATA13
spermatogenesis associated 13
chrX_+_15435351 0.553 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr17_-_36719030 0.552 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr1_-_54392030 0.552 NM_201546
CDCP2
CUB domain containing protein 2
chr10_+_26767698 0.551 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr22_+_43476755 0.548 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr3_-_127303080 0.547 NM_001164475
SLC41A3
solute carrier family 41, member 3
chr21_-_36774257 0.545 NM_001146079
NM_144492
CLDN14

claudin 14

chr12_+_131577229 0.543 NM_001142641
FBRSL1
fibrosin-like 1
chr5_-_138842408 0.543 TMEM173
transmembrane protein 173
chr3_+_66527586 0.543


chr9_-_139043035 0.543 NM_212533
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr5_-_945613 0.543 NM_001009877
BRD9
bromodomain containing 9
chr5_+_176449156 0.540 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr19_+_62434188 0.538 NM_001015879
NM_003160
NM_001015878
AURKC


aurora kinase C


chr3_-_158700036 0.535 NM_024621
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr1_-_159306273 0.535 ARHGAP30
Rho GTPase activating protein 30
chrX_+_133952633 0.533 NM_001163438
LOC644538
hypothetical protein LOC644538
chr19_-_18891190 0.533 COPE
coatomer protein complex, subunit epsilon
chr13_-_32658215 0.529 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_+_66927955 0.525 TBC1D10C
TBC1 domain family, member 10C
chr20_+_55359992 0.524 NM_001015885
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr1_-_31003181 0.524 LAPTM5
lysosomal protein transmembrane 5
chr1_+_17404206 0.522 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr19_+_52940610 0.521 GLTSCR2
glioma tumor suppressor candidate region gene 2
chr3_-_162305319 0.520 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr11_-_8911110 0.520 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr1_-_38046433 0.518 YRDC
yrdC domain containing (E. coli)
chr17_+_15788955 0.516 NM_000676
ADORA2B
adenosine A2b receptor
chr22_-_19543069 0.515 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_4442610 0.511 HDGFRP2
hepatoma-derived growth factor-related protein 2
chr1_+_29435534 0.511 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr1_+_28867876 0.509 GMEB1
glucocorticoid modulatory element binding protein 1
chr1_-_38046439 0.509 NM_024640
YRDC
yrdC domain containing (E. coli)
chr22_+_19543350 0.507 SNAP29
synaptosomal-associated protein, 29kDa
chr3_-_156904690 0.507 NM_014996
PLCH1
phospholipase C, eta 1
chr2_-_242205556 0.505 NM_001164356
THAP4
THAP domain containing 4
chr1_+_6008999 0.504 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr15_+_41672543 0.503 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr1_+_3531410 0.503 NM_182752
TPRG1L
tumor protein p63 regulated 1-like
chrX_+_67830204 0.496 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chr1_-_230717850 0.496 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr5_+_180583315 0.494 TRIM41
tripartite motif containing 41
chr17_+_45965076 0.494 EPN3
epsin 3
chr15_-_38908197 0.493 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.