Motif ID: FOXA2.p3

Z-value: 1.412


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2



Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_110890719 1.991 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr6_-_32227695 1.620 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr5_+_149960820 1.436 NM_001166208
SYNPO
synaptopodin
chr6_-_32227645 1.423 PRRT1
proline-rich transmembrane protein 1
chr1_-_120155581 1.392 NM_001159352
NM_001159353
NM_032044
REG4


regenerating islet-derived family, member 4


chr1_+_150753601 1.384 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr4_-_152368492 1.347 SH3D19
SH3 domain containing 19
chr9_-_111230926 1.337 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr18_+_59405513 1.255 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_67039518 1.227 NM_005478
INSL5
insulin-like 5
chr1_-_229627412 1.187 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr12_+_123339662 1.164 NM_181709
FAM101A
family with sequence similarity 101, member A
chr5_+_145296313 1.114 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr2_-_101457596 1.072 NM_001145664
RFX8
regulatory factor X, 8
chr1_+_13784553 1.041 NM_001006624
NM_001006625
PDPN

podoplanin

chr2_-_171725604 1.026 NM_012290
TLK1
tousled-like kinase 1
chr7_+_28305464 1.022 NM_182899
CREB5
cAMP responsive element binding protein 5
chr7_+_116238309 1.018 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr16_+_68516401 0.973 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr11_-_6746763 0.950 NM_001004490
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr12_+_32578513 0.943 FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_+_137224266 0.910 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_124294355 0.904 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr5_-_36337756 0.903 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr1_+_171871283 0.882 NM_001195190
LOC730159
hypothetical protein LOC730159
chr2_+_108590032 0.878 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_+_120029426 0.866 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr7_+_142850667 0.865 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr2_+_173394560 0.817 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_176059763 0.811 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr13_+_77007809 0.809 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr1_+_205344200 0.800 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr1_-_150599105 0.791 NM_001014342
FLG2
filaggrin family member 2
chr8_+_12847521 0.790 NM_020844
KIAA1456
KIAA1456
chrX_+_135558001 0.786 NM_000074
CD40LG
CD40 ligand
chr1_+_24518398 0.785 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr8_-_134141586 0.784 NM_006748
SLA
Src-like-adaptor
chr9_-_4142182 0.784 NM_152629
GLIS3
GLIS family zinc finger 3
chr6_-_26038817 0.780 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr1_-_150079656 0.763 NM_001136003
C2CD4D
C2 calcium-dependent domain containing 4D
chr4_-_186693574 0.749 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr6_-_159386007 0.746 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr3_+_188197029 0.743


chr15_+_94670160 0.729 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_176577228 0.728 NM_004841
RASAL2
RAS protein activator like 2
chr1_+_198263352 0.724 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr2_+_38009405 0.708 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr7_+_129693938 0.707 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr7_+_116151411 0.707 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr1_-_177106702 0.698 NM_004673
ANGPTL1
angiopoietin-like 1
chr2_-_134042500 0.698 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr12_+_27740694 0.697 NM_001029874
REP15
RAB15 effector protein
chr8_-_81155564 0.679 NM_001025252
TPD52
tumor protein D52
chr1_-_150564302 0.676 NM_002016
FLG
filaggrin
chr11_-_107087943 0.672 NM_003063
SLN
sarcolipin
chr2_-_87102453 0.672 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr10_+_18729518 0.656 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr17_-_74361975 0.652 TIMP2
TIMP metallopeptidase inhibitor 2
chr16_+_52027020 0.642 RBL2
retinoblastoma-like 2 (p130)
chr1_+_200018380 0.641 NAV1
neuron navigator 1
chr1_+_24522116 0.631 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_58237742 0.628 NM_001100875
MARCH10
membrane-associated ring finger (C3HC4) 10
chr7_+_94377145 0.619 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chrX_-_10761729 0.616 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_117640078 0.610


chrX_-_15243647 0.606 NM_080873
ASB11
ankyrin repeat and SOCS box containing 11
chr15_+_66711380 0.605 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr12_-_102968044 0.599 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr3_-_150569574 0.598 TM4SF1
transmembrane 4 L six family member 1
chr1_+_15351585 0.593 NM_001136216
NM_001136217
TMEM51

transmembrane protein 51

chr12_-_55614311 0.591 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr10_-_21847126 0.591


chr17_+_3326045 0.588 NM_000049
ASPA
aspartoacylase
chr8_-_25338472 0.584 NM_000825
NM_001083111
GNRH1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

chr12_+_21570457 0.580 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr12_-_7487989 0.578 NM_174941
CD163L1
CD163 molecule-like 1
chr14_+_20429382 0.571 NM_002935
RNASE2
RNASE3
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ribonuclease, RNase A family, 3
chr4_+_14950657 0.567 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr1_+_169747788 0.567 PRRC2C
proline-rich coiled-coil 2C
chr10_+_51219558 0.556 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr11_-_27679617 0.552 NM_170733
BDNF
brain-derived neurotrophic factor
chr1_+_170656450 0.550 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr4_-_152316105 0.549 NM_001128924
SH3D19
SH3 domain containing 19
chr3_-_191650291 0.546 NM_207316
TMEM207
transmembrane protein 207
chr1_+_204484081 0.546 NM_001910
NM_148964
CTSE

cathepsin E

chr18_+_50646616 0.545 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr8_-_108579270 0.541 NM_001146
ANGPT1
angiopoietin 1
chr12_+_5473558 0.532 NM_002527
NTF3
neurotrophin 3
chr11_+_55407348 0.532 NM_032681
SPRYD5
SPRY domain containing 5
chr3_+_195336625 0.531 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chrX_+_135441970 0.530 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr7_-_27102049 0.528 NM_005522
NM_153620
HOXA1

homeobox A1

chr14_+_54238581 0.522 SAMD4A
sterile alpha motif domain containing 4A
chr2_-_20390601 0.519 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr3_-_115380539 0.518 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr11_-_57792206 0.517 NM_207374
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr1_+_34997928 0.515 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr11_+_120478584 0.513 NM_005422
TECTA
tectorin alpha
chr3_+_173954940 0.511 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr21_+_29439768 0.510 C21orf7
chromosome 21 open reading frame 7
chr4_+_14985272 0.509 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr3_-_150993299 0.490 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr6_-_89984214 0.481 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr6_+_74462654 0.479 CD109
CD109 molecule
chr3_-_71715431 0.478 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr6_+_134800533 0.478 LOC154092
hypothetical LOC154092
chr15_-_68128924 0.476 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr17_-_36418869 0.474 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr14_-_93859394 0.469 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr14_-_76612286 0.469


chr2_-_69033515 0.469 NM_182536
GKN2
gastrokine 2
chr18_-_50777634 0.466 NM_025214
CCDC68
coiled-coil domain containing 68
chr3_+_195336631 0.464 HES1
hairy and enhancer of split 1, (Drosophila)
chr12_+_53534565 0.464 NM_058173
MUCL1
mucin-like 1
chr20_+_9406460 0.463 PLCB4
phospholipase C, beta 4
chr11_-_4555625 0.461 NM_144663
C11orf40
chromosome 11 open reading frame 40
chr10_+_124310170 0.458 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr1_+_40486159 0.457 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr12_-_102967828 0.455 GLT8D2
glycosyltransferase 8 domain containing 2
chrX_-_48655978 0.454 PIM2
pim-2 oncogene
chrX_+_10084984 0.452 NM_001830
CLCN4
chloride channel 4
chr1_+_15351885 0.452 TMEM51
transmembrane protein 51
chr1_-_57204208 0.451 NM_000066
C8B
complement component 8, beta polypeptide
chr11_-_9243408 0.451 NM_015213
DENND5A
DENN/MADD domain containing 5A
chr8_-_93099040 0.448 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr21_+_38550739 0.445 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_-_20636909 0.445 NM_001101672
ZNF219
zinc finger protein 219
chr6_-_112682573 0.445 LAMA4
laminin, alpha 4
chr7_+_142723340 0.441 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr5_-_13997588 0.439 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr15_+_60146467 0.437 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr1_-_20682541 0.435


chr12_+_9925354 0.435 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr6_-_136829705 0.434 NM_001198615
MAP7
microtubule-associated protein 7
chr17_-_36074812 0.433 NM_152349
KRT222
keratin 222
chr7_+_80069439 0.433 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr5_-_58607673 0.431 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_123083096 0.431 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr11_+_109468734 0.431 ZC3H12C
zinc finger CCCH-type containing 12C
chr3_+_23904086 0.430 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr22_+_19458378 0.429 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_-_10464308 0.429 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr2_+_11591692 0.428 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr3_+_38322430 0.427 NM_004803
SLC22A14
solute carrier family 22, member 14
chr1_-_115039614 0.424 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr15_-_48198697 0.420 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr5_+_102229425 0.420 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr16_+_29697090 0.420 ZG16
zymogen granule protein 16 homolog (rat)
chr11_+_55776251 0.419 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr5_+_125828685 0.416 NM_001146322
GRAMD3
GRAM domain containing 3
chr1_+_198278339 0.416 NR5A2
nuclear receptor subfamily 5, group A, member 2
chr10_-_125843092 0.415 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr12_-_68379331 0.413 NM_032735
BEST3
bestrophin 3
chr4_+_159662349 0.411 NM_021634
RXFP1
relaxin/insulin-like family peptide receptor 1
chr6_+_74462485 0.410 CD109
CD109 molecule
chr1_-_201586910 0.408 NM_002023
FMOD
fibromodulin
chr8_-_125785611 0.408 MTSS1
metastasis suppressor 1
chr2_-_21081694 0.406 APOB
apolipoprotein B (including Ag(x) antigen)
chr3_+_99370233 0.403 NM_001005515
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr2_-_55053398 0.401


chr6_+_144227265 0.401 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr11_+_5714253 0.394 NM_001005180
OR56B1
olfactory receptor, family 56, subfamily B, member 1
chr3_-_194579207 0.394 NM_198505
ATP13A5
ATPase type 13A5
chr7_+_89681069 0.393 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr3_+_173043832 0.383 NM_001164436
TMEM212
transmembrane protein 212
chr17_-_36409632 0.383 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr16_+_75790849 0.382 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr7_+_134226727 0.380 CALD1
caldesmon 1
chr5_+_92944680 0.374 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr18_+_3402071 0.373 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr2_+_178893216 0.373 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr6_+_74462630 0.372 CD109
CD109 molecule
chr5_+_55182963 0.371 NM_139017
IL31RA
interleukin 31 receptor A
chr12_-_14929991 0.371 NM_000900
NM_001190839
MGP

matrix Gla protein

chr5_-_42847716 0.371 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr9_-_21472311 0.368 NM_176891
IFNE
interferon, epsilon
chr10_-_129581192 0.368 NM_152311
CLRN3
clarin 3
chr4_-_40327396 0.366 RBM47
RNA binding motif protein 47
chr17_-_36559579 0.363 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr12_-_11066436 0.362 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr3_+_50687675 0.361 NM_004947
DOCK3
dedicator of cytokinesis 3
chr4_-_100575313 0.360 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr10_-_7699192 0.360 ITIH5
inter-alpha (globulin) inhibitor H5
chr1_+_218768423 0.360 MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_-_205272619 0.360 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr8_+_21967008 0.360 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr17_-_36436979 0.359 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr5_-_16561936 0.359 NM_019000
FAM134B
family with sequence similarity 134, member B
chr14_-_20636568 0.355 NM_016423
ZNF219
zinc finger protein 219
chr8_-_82606104 0.354 NM_001105281
FABP12
fatty acid binding protein 12
chr2_+_113601616 0.353 IL1RN
interleukin 1 receptor antagonist
chr7_+_100037817 0.352 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr3_-_139315011 0.349 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr8_+_143758875 0.349 NM_005672
PSCA
prostate stem cell antigen
chr9_-_34700062 0.349 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chrX_+_47748677 0.348 NM_205856
SPACA5
sperm acrosome associated 5
chrX_+_118598325 0.348 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr7_+_47661366 0.347 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr6_+_154402135 0.346 NM_000914
NM_001008503
NM_001008504
NM_001008505
NM_001145282
NM_001145283
NM_001145285
NM_001145286
NM_001145284
OPRM1








opioid receptor, mu 1








chr2_+_177210683 0.344



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
151.40 4.39e-03 GO:0051043 regulation of membrane protein ectodomain proteolysis
27.53 8.72e-03 GO:0030162 regulation of proteolysis

Nothing significant found in compartment category.

Nothing significant found in function category.