Motif ID: FOXL1.p2

Z-value: 1.639


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1



Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_45899080 1.996 IGFBP1
insulin-like growth factor binding protein 1
chr7_+_45899621 1.877


chr4_-_152368492 1.875 SH3D19
SH3 domain containing 19
chr7_-_107230867 1.814 NM_000111
SLC26A3
solute carrier family 26, member 3
chr5_+_140757787 1.736 NM_018925
NM_032099
PCDHGB5

protocadherin gamma subfamily B, 5

chr7_-_99312591 1.577 NM_001005276
OR2AE1
olfactory receptor, family 2, subfamily AE, member 1
chrX_+_21960841 1.548 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr7_+_142723340 1.533 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr5_+_140772691 1.385 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr5_+_140762551 1.357 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr7_+_134114701 1.302 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr5_-_16561936 1.295 NM_019000
FAM134B
family with sequence similarity 134, member B
chr10_-_97190885 1.235 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr6_+_131613196 1.223 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr5_+_140719773 1.220 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr3_-_150533948 1.218 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_+_181380837 1.202 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr7_+_142629251 1.198 NM_176882
TAS2R40
taste receptor, type 2, member 40
chr17_-_15463742 1.195 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr10_-_69095362 1.195 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr3_-_195601283 1.194 NM_004488
GP5
glycoprotein V (platelet)
chr15_-_68781662 1.170 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_+_141054621 1.170 NM_001105558
WEE2
WEE1 homolog 2 (S. pombe)
chrX_+_41468351 1.144 NM_080817
GPR82
G protein-coupled receptor 82
chr7_+_94377145 1.121 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr4_+_88748704 1.098 NM_014208
DSPP
dentin sialophosphoprotein
chr10_+_90511142 1.093 NM_001102469
LIPN
lipase, family member N
chrX_+_99726445 1.085 NM_022144
TNMD
tenomodulin
chrX_+_37750778 1.084 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr3_+_153014550 1.083 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr1_+_246375072 1.043 NM_001004690
OR2M5
olfactory receptor, family 2, subfamily M, member 5
chr4_+_73123712 1.031 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr17_-_8004671 1.025 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr12_+_79625538 1.011 NM_002469
MYF6
myogenic factor 6 (herculin)
chr6_-_25834733 1.004 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr1_-_116185215 1.003 NM_005599
NHLH2
nescient helix loop helix 2
chr3_-_148607096 1.000 NM_032153
ZIC4
Zic family member 4
chr16_+_24174374 0.995 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr9_+_129066576 0.992 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr1_+_234748187 0.991 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr7_+_89681069 0.988 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr11_-_13474101 0.972 NM_000315
PTH
parathyroid hormone
chr7_+_134114912 0.957 CALD1
caldesmon 1
chr1_-_150328153 0.954 NM_001008536
TCHHL1
trichohyalin-like 1
chr6_+_132901119 0.949 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr7_+_143263191 0.944 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr4_+_3341521 0.933 NM_198227
RGS12
regulator of G-protein signaling 12
chr7_-_113346284 0.913 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr1_-_177106702 0.903 NM_004673
ANGPTL1
angiopoietin-like 1
chr5_+_156628929 0.899 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr7_-_130021845 0.890 NM_052933
TSGA13
testis specific, 13
chr4_+_71492581 0.888 NM_016519
AMBN
ameloblastin (enamel matrix protein)
chr7_+_142850667 0.888 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr3_+_129117007 0.887 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr16_+_70646008 0.877 NM_001126102
NM_005143
HP

haptoglobin

chrX_-_50403412 0.876 SHROOM4
shroom family member 4
chr1_+_246195157 0.868 NM_001004491
OR2AK2
olfactory receptor, family 2, subfamily AK, member 2
chr8_-_27997306 0.866 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr8_+_50147455 0.860 NM_001007176
C8orf22
chromosome 8 open reading frame 22
chr5_+_139485703 0.857 NM_001007189
C5orf53
chromosome 5 open reading frame 53
chr16_-_11277806 0.856 NM_002762
PRM2
protamine 2
chr19_-_14030970 0.854 NM_001145028
PALM3
paralemmin 3
chr4_+_88939725 0.853 NM_004967
IBSP
integrin-binding sialoprotein
chr1_+_158603480 0.849 NM_005598
NHLH1
nescient helix loop helix 1
chr2_+_158666627 0.848 NM_173355
UPP2
uridine phosphorylase 2
chr3_-_139315011 0.845 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr2_+_64540843 0.843 HSPC159
galectin-related protein
chr12_-_7547552 0.843 NM_004244
NM_203416
CD163

CD163 molecule

chr13_+_110653407 0.838 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr11_-_6148131 0.825 NM_001004052
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chr5_+_156540425 0.824 NM_005546
ITK
IL2-inducible T-cell kinase
chr1_-_153107084 0.823


chr11_+_7574992 0.823 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr18_+_50409387 0.814 NM_173629
C18orf26
chromosome 18 open reading frame 26
chr1_+_242281199 0.813 ZNF238
zinc finger protein 238
chr1_+_200775864 0.813 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr17_+_63367052 0.809 BPTF
bromodomain PHD finger transcription factor
chr22_-_14829803 0.788 NM_001005239
OR11H1
olfactory receptor, family 11, subfamily H, member 1
chrX_-_15593074 0.778 NM_020665
TMEM27
transmembrane protein 27
chr9_+_102380156 0.777 NM_001018116
MURC
muscle-related coiled-coil protein
chr20_+_56455866 0.767 VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr3_-_49204294 0.766 NM_001080528
LOC646498
hypothetical protein LOC646498
chr6_-_26038817 0.766 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr17_-_36209672 0.764 NM_181535
KRT28
keratin 28
chr5_+_76470829 0.761


chr11_+_123315459 0.760 NM_001001965
OR4D5
olfactory receptor, family 4, subfamily D, member 5
chr11_+_124294355 0.758 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr10_+_114033403 0.754 NM_058222
TECTB
tectorin beta
chrX_+_55666557 0.745 NM_198451
FOXR2
forkhead box R2
chr8_-_7297296 0.729 NM_058206
NM_058207
SPAG11B

sperm associated antigen 11B

chr1_-_201321999 0.728 NM_002479
MYOG
myogenin (myogenic factor 4)
chr3_-_102194938 0.727 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr7_+_134114957 0.726 CALD1
caldesmon 1
chr5_-_58918031 0.720 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_108311872 0.718 NM_001024607
C7orf66
chromosome 7 open reading frame 66
chrX_+_54963953 0.717 NM_001039705
NM_016157
NM_177556
TRO


trophinin


chr1_+_116455898 0.716 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr21_-_30614477 0.712 NM_203405
KRTAP26-1
keratin associated protein 26-1
chr5_+_140730014 0.709 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr7_+_128099581 0.708 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chrX_-_11194015 0.707 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr14_-_56346849 0.701 NM_021728
OTX2
orthodenticle homeobox 2
chr9_+_42707229 0.689 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr1_+_65503011 0.684 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_+_29707583 0.683 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr3_+_12367993 0.679 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr10_-_21847126 0.671


chr1_-_75849350 0.671 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr1_-_150398327 0.671 NM_001122965
RPTN
repetin
chr22_+_27779877 0.669 ZNRF3
zinc and ring finger 3
chr1_+_103898844 0.664 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr2_-_180319013 0.664 NM_001113397
ZNF385B
zinc finger protein 385B
chr7_+_123083096 0.661 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr1_-_166779825 0.659 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr6_-_117256890 0.659 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr6_+_136214495 0.657 NM_018945
PDE7B
phosphodiesterase 7B
chr12_+_9713472 0.656 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr10_-_61819493 0.654 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_114295289 0.651 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr12_-_14858358 0.644 NM_001013698
C12orf69
chromosome 12 open reading frame 69
chr8_-_134141586 0.643 NM_006748
SLA
Src-like-adaptor
chr3_-_121445831 0.641 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chr1_+_13903936 0.640 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr1_+_242281175 0.627 NM_205768
ZNF238
zinc finger protein 238
chr15_+_66695932 0.625 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chrX_+_135558001 0.621 NM_000074
CD40LG
CD40 ligand
chr11_-_40271086 0.620 LRRC4C
leucine rich repeat containing 4C
chr12_+_32546243 0.620 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_-_123758448 0.619 NM_001005468
OR8B2
olfactory receptor, family 8, subfamily B, member 2
chr1_+_17448179 0.619 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr6_-_136888771 0.618 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr7_-_50596238 0.617 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr1_-_161439248 0.617 NM_001195303
RGS5
regulator of G-protein signaling 5
chr3_-_15538164 0.617 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chrX_+_123062143 0.616 STAG2
stromal antigen 2
chr8_+_67568044 0.615 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr7_+_143287952 0.614 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr6_+_155579788 0.614 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_+_151209751 0.612 NM_173080
SPRR4
small proline-rich protein 4
chrX_+_10084984 0.611 NM_001830
CLCN4
chloride channel 4
chr15_+_19883745 0.610 NM_001005241
OR4N4
olfactory receptor, family 4, subfamily N, member 4
chr15_+_26832300 0.603 LOC100289656
Dexi homolog (mouse) pseudogene
chr8_-_82606104 0.602 NM_001105281
FABP12
fatty acid binding protein 12
chr4_+_14950657 0.598 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr11_+_57547928 0.598 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr8_+_24354387 0.598 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr1_-_201583989 0.597 FMOD
fibromodulin
chr8_-_62764839 0.585 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr3_-_115380539 0.583 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr6_-_134540666 0.583 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_18134319 0.580 NM_024730
RERGL
RERG/RAS-like
chr3_+_143824955 0.577 NM_002670
PLS1
plastin 1
chr1_+_92405196 0.565 NM_015237
KIAA1107
KIAA1107
chr1_-_54256390 0.560 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr1_+_207926172 0.555 NM_181755
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr4_+_72321113 0.554 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chrX_-_21686079 0.553 NM_014332
SMPX
small muscle protein, X-linked
chrX_+_38096679 0.552 NM_000531
OTC
ornithine carbamoyltransferase
chr1_-_181889070 0.552 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr3_+_162697289 0.551 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr1_-_161439487 0.551 NM_003617
RGS5
regulator of G-protein signaling 5
chr17_-_36409632 0.551 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr10_+_102111361 0.550 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chrX_-_57180782 0.549 NM_019003
SPIN2A
spindlin family, member 2A
chr1_+_181421984 0.545 LAMC2
laminin, gamma 2
chr1_+_151081953 0.543 NM_001128600
LCE6A
late cornified envelope 6A
chr6_-_33268177 0.543 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr9_+_124463665 0.533 NM_001005236
OR1L1
olfactory receptor, family 1, subfamily L, member 1
chr21_-_30460841 0.532 NM_012131
CLDN17
claudin 17
chr7_-_96471544 0.531 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chrX_-_131089552 0.531 NM_194277
FRMD7
FERM domain containing 7
chr1_-_199613406 0.531 TNNT2
troponin T type 2 (cardiac)
chr4_+_71283383 0.530 NM_006685
SMR3B
submaxillary gland androgen regulated protein 3B
chr2_-_55090759 0.525 NM_007008
RTN4
reticulon 4
chr10_-_30958631 0.521 NM_183058
LYZL2
lysozyme-like 2
chr4_+_120276386 0.520 NM_016599
MYOZ2
myozenin 2
chr8_-_42353719 0.518 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr12_+_54172413 0.517 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr7_+_80069439 0.517 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr1_+_245818284 0.514 NM_001001915
OR2G2
olfactory receptor, family 2, subfamily G, member 2
chr1_-_24311212 0.510 NM_152372
MYOM3
myomesin family, member 3
chr6_-_136889302 0.510 MAP7
microtubule-associated protein 7
chr1_-_227636462 0.509 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chr8_-_52884456 0.509 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chrX_-_24241352 0.507 NM_001136233
FAM48B2
family with sequence similarity 48, member B2
chr10_-_116434102 0.504 ABLIM1
actin binding LIM protein 1
chr11_+_123625632 0.504 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr9_+_124321239 0.503 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr11_-_85146691 0.503 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr11_+_58980986 0.502 NM_001004708
OR4D6
olfactory receptor, family 4, subfamily D, member 6
chr3_+_42702014 0.500 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chrX_-_142632181 0.499 NM_001009615
SPANXN2
SPANX family, member N2
chr12_+_53901075 0.497 NM_001005280
OR10A7
olfactory receptor, family 10, subfamily A, member 7
chr18_+_28023984 0.495 NM_005925
MEP1B
meprin A, beta
chr19_+_60077360 0.493 NM_002000
NM_133269
NM_133271
NM_133272
NM_133273
NM_133274
NM_133277
NM_133278
NM_133279
FCAR








Fc fragment of IgA, receptor for








chr5_+_121523769 0.493 NM_001195535
LOC728460
hypothetical LOC728460
chr11_+_4976788 0.491 NM_001004755
OR51L1
olfactory receptor, family 51, subfamily L, member 1
chr6_-_132987106 0.487 NM_001033080
TAAR2
trace amine associated receptor 2
chr3_+_50291521 0.484 NM_153215
C3orf45
chromosome 3 open reading frame 45
chr10_+_35524835 0.484 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator





Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
5.55 9.19e-03 GO:0022610 biological adhesion
14.47 2.21e-02 GO:0007156 homophilic cell adhesion

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.20 1.47e-02 GO:0071944 cell periphery
1.78 4.16e-02 GO:0044425 membrane part

Nothing significant found in function category.