Motif ID: FOXN1.p2

Z-value: 1.560


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1



Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_36196523 2.104 NM_006194
PAX9
paired box 9
chr2_-_142605010 1.827 LRP1B
low density lipoprotein receptor-related protein 1B
chr10_+_103103797 1.634 NM_003939
NM_033637
BTRC

beta-transducin repeat containing

chr2_-_54051290 1.369 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr17_+_40581704 1.245 HEXIM1
hexamethylene bis-acetamide inducible 1
chr20_-_25010756 1.191 NM_014588
NM_199425
VSX1

visual system homeobox 1

chrX_+_90920915 1.121 NM_032967
PCDH11X
PCDH11Y
protocadherin 11 X-linked
protocadherin 11 Y-linked
chr20_-_2592777 1.100 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr20_+_29656744 1.067 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr14_+_30564433 1.062 NM_001128126
NM_007077
AP4S1

adaptor-related protein complex 4, sigma 1 subunit

chr1_-_45924770 1.039 NM_021639
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr20_+_3749164 1.037 NM_018347
C20orf29
chromosome 20 open reading frame 29
chr8_+_65656164 1.024 BHLHE22
basic helix-loop-helix family, member e22
chr4_-_170770111 1.014 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr4_+_81475897 0.970 NM_152770
C4orf22
chromosome 4 open reading frame 22
chr3_+_139388770 0.952 NM_014154
NM_015396
NM_213654
ARMC8


armadillo repeat containing 8


chr5_+_80292213 0.951 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr17_-_42250961 0.944 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr14_-_87859284 0.919 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr12_+_56230073 0.869 KIF5A
kinesin family member 5A
chr10_+_112394094 0.859 NM_001134363
RBM20
RNA binding motif protein 20
chr17_+_11442472 0.841 NM_001372
DNAH9
dynein, axonemal, heavy chain 9
chr20_+_3775421 0.835 NM_020746
MAVS
mitochondrial antiviral signaling protein
chr16_+_25610847 0.833 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr12_+_56230047 0.825 KIF5A
kinesin family member 5A
chr14_+_34585098 0.819 NM_173607
FAM177A1
family with sequence similarity 177, member A1
chr9_+_8848130 0.813


chr1_-_25129354 0.801 NM_004350
RUNX3
runt-related transcription factor 3
chr19_+_2240996 0.801


chr12_+_56230110 0.801 NM_004984
KIF5A
kinesin family member 5A
chr20_-_48163071 0.793 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr15_-_32875040 0.790 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr22_+_47263919 0.785 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_-_8982107 0.778 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr4_+_3738093 0.774 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr16_+_1143738 0.759 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr2_+_120018494 0.754 NM_001029996
PCDP1
primary ciliary dyskinesia protein 1
chr1_-_183210155 0.751 FAM129A
family with sequence similarity 129, member A
chr5_-_100266769 0.750 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr5_-_134899537 0.747 NM_006161
NEUROG1
neurogenin 1
chr3_-_191321367 0.744 LEPREL1
leprecan-like 1
chr17_+_33761234 0.741 NM_014598
SOCS7
suppressor of cytokine signaling 7
chrX_-_21586337 0.740 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr20_-_19981005 0.730 CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr11_-_132318741 0.729 OPCML
opioid binding protein/cell adhesion molecule-like
chr5_+_80292313 0.725 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr11_-_75599433 0.723 WNT11
wingless-type MMTV integration site family, member 11
chr8_+_21937533 0.723 NPM2
nucleophosmin/nucleoplasmin 2
chr1_+_82038669 0.717 NM_012302
LPHN2
latrophilin 2
chr14_-_91372365 0.715 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr2_+_30523586 0.713 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr14_-_22127902 0.711 DAD1
defender against cell death 1
chr16_+_56038837 0.707 NM_020312
COQ9
coenzyme Q9 homolog (S. cerevisiae)
chr17_-_35273947 0.704 NM_012481
NM_183228
NM_183229
NM_183230
NM_183231
NM_183232
IKZF3





IKAROS family zinc finger 3 (Aiolos)





chr15_+_39008822 0.703 NM_019074
DLL4
delta-like 4 (Drosophila)
chr16_-_56038771 0.703 NM_020313
CIAPIN1
cytokine induced apoptosis inhibitor 1
chr22_+_27798887 0.700 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chrX_-_137621060 0.699 FGF13
fibroblast growth factor 13
chr12_-_79855580 0.689 LIN7A
lin-7 homolog A (C. elegans)
chr2_-_200424140 0.685 LOC348751
hypothetical LOC348751
chr17_-_37586716 0.679 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr17_+_7125702 0.664 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr4_-_111763655 0.660 NM_000325
PITX2
paired-like homeodomain 2
chr4_-_21559471 0.660 NM_147182
KCNIP4
Kv channel interacting protein 4
chr11_-_107969554 0.657 NM_015065
EXPH5
exophilin 5
chr1_+_95355415 0.654 NM_152487
TMEM56
transmembrane protein 56
chr17_+_76133206 0.653 NM_001163034
NM_020761
RPTOR

regulatory associated protein of MTOR, complex 1

chrX_+_101267315 0.653 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr19_-_51856129 0.652 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr17_+_76133337 0.634 RPTOR
regulatory associated protein of MTOR, complex 1
chr19_-_11452439 0.633 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr12_+_4889309 0.621 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr2_+_187059115 0.613 NM_018471
ZC3H15
zinc finger CCCH-type containing 15
chr1_-_25129305 0.610 RUNX3
runt-related transcription factor 3
chr2_-_219614481 0.608 NM_152389
NM_194302
CCDC108

coiled-coil domain containing 108

chr14_-_22127954 0.601 NM_001344
DAD1
defender against cell death 1
chr2_+_232534535 0.592 NM_152383
DIS3L2
DIS3 mitotic control homolog (S. cerevisiae)-like 2
chr1_+_78243181 0.591 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr11_-_93774223 0.587 NM_016540
GPR83
G protein-coupled receptor 83
chr11_-_27341251 0.585 NM_030771
NM_080654
CCDC34

coiled-coil domain containing 34

chr3_+_3816079 0.583 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr15_-_47235057 0.583 NM_001143887
NM_004236
COPS2

COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)

chr2_+_190014403 0.580 NM_032168
WDR75
WD repeat domain 75
chr13_-_52320774 0.566 NM_002590
NM_032949
PCDH8

protocadherin 8

chr4_+_172971149 0.565 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr20_+_254205 0.564 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr8_-_38245694 0.563 NM_001102559
NM_001102560
NM_032483
PPAPDC1B


phosphatidic acid phosphatase type 2 domain containing 1B


chr17_-_17081217 0.559 NM_144606
NM_144997
FLCN

folliculin

chr10_+_101282679 0.557 NM_145285
NKX2-3
NK2 transcription factor related, locus 3 (Drosophila)
chr2_+_187059277 0.549 ZC3H15
zinc finger CCCH-type containing 15
chr2_+_190014432 0.548 WDR75
WD repeat domain 75
chr9_+_96176638 0.543 NM_032558
HIATL1
hippocampus abundant transcript-like 1
chr10_+_124211353 0.541 HTRA1
HtrA serine peptidase 1
chr4_-_155631861 0.540 DCHS2
dachsous 2 (Drosophila)
chr11_-_88864061 0.540 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr2_-_43676603 0.536 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr2_+_99320181 0.528 NM_015904
EIF5B
eukaryotic translation initiation factor 5B
chr20_-_18395622 0.520 NM_001099407
C20orf12
chromosome 20 open reading frame 12
chr2_+_220007943 0.519 NM_005876
SPEG
SPEG complex locus
chr3_-_121944052 0.515 NM_173825
RABL3
RAB, member of RAS oncogene family-like 3
chr11_+_65311104 0.514 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr14_+_92330383 0.511 NM_005113
GOLGA5
golgin A5
chr12_-_79855618 0.509 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr18_-_30056431 0.508 NM_001198547
NOL4
nucleolar protein 4
chr15_+_47235243 0.506 NM_001001556
GALK2
galactokinase 2
chr17_+_34871775 0.505 CDK12
cyclin-dependent kinase 12
chr5_-_134397740 0.498 NM_002653
PITX1
paired-like homeodomain 1
chr9_-_95757365 0.492 NM_021570
BARX1
BARX homeobox 1
chr2_+_187059237 0.491 ZC3H15
zinc finger CCCH-type containing 15
chr17_-_45562112 0.487 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr14_+_64077171 0.486 HSPA2
heat shock 70kDa protein 2
chr14_+_51526071 0.484 C14orf166
chromosome 14 open reading frame 166
chr10_-_119124727 0.479 NM_173791
PDZD8
PDZ domain containing 8
chr2_-_202215593 0.477 NM_152388
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr2_-_176656935 0.474 NM_001080458
EVX2
even-skipped homeobox 2
chr11_+_7997366 0.473 TUB
tubby homolog (mouse)
chr8_+_121892719 0.472


chr8_+_87424074 0.470 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr2_-_154043403 0.465 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr9_-_95757448 0.460 BARX1
BARX homeobox 1
chr11_+_65311142 0.459 OVOL1
ovo-like 1(Drosophila)
chr2_+_185171480 0.459 ZNF804A
zinc finger protein 804A
chr4_+_119419354 0.455 SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr22_+_40195058 0.452 NM_001098
ACO2
aconitase 2, mitochondrial
chr3_-_134863316 0.450 NM_007027
TOPBP1
topoisomerase (DNA) II binding protein 1
chr2_+_68548173 0.449 NM_173545
APLF
aprataxin and PNKP like factor
chr10_-_69762654 0.449 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr16_-_730889 0.445 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr6_+_99389300 0.444 NM_005604
POU3F2
POU class 3 homeobox 2
chr4_-_1683712 0.444 NM_006527
SLBP
stem-loop binding protein
chr5_-_45731976 0.441 NM_021072
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr5_-_134397470 0.440 PITX1
paired-like homeodomain 1
chr15_+_76343540 0.439 NM_018602
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chrX_+_105856531 0.439 NM_194463
RNF128
ring finger protein 128
chr16_+_84490267 0.436 NM_002163
IRF8
interferon regulatory factor 8
chr15_-_76210611 0.431 NM_006383
CIB2
calcium and integrin binding family member 2
chr3_-_192063158 0.428 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr2_+_210575600 0.427 NM_199229
RPE
ribulose-5-phosphate-3-epimerase
chr17_+_77478858 0.426 LOC92659
hypothetical LOC92659
chr12_+_87060176 0.425 NM_181783
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr7_-_50828159 0.420 GRB10
growth factor receptor-bound protein 10
chr14_+_51525942 0.418 NM_016039
C14orf166
chromosome 14 open reading frame 166
chr16_+_70486933 0.418 NM_014761
KIAA0174
KIAA0174
chrX_-_17789276 0.416 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr4_-_66218777 0.412 EPHA5
EPH receptor A5
chr19_+_40325993 0.412 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr2_+_210575566 0.410 NM_006916
RPE
ribulose-5-phosphate-3-epimerase
chr15_-_38000379 0.409 NM_007223
GPR176
G protein-coupled receptor 176
chr10_-_6059460 0.409 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr15_+_74416129 0.408 ISL2
ISL LIM homeobox 2
chr5_+_93980108 0.406 NM_032290
ANKRD32
ankyrin repeat domain 32
chr17_-_44663107 0.404 NM_001143804
NM_178500
PHOSPHO1

phosphatase, orphan 1

chr3_+_121944247 0.402 NM_005513
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr6_+_117693413 0.399 NM_153453
NM_182645
VGLL2

vestigial like 2 (Drosophila)

chr7_-_33068699 0.398 NM_001002010
NT5C3
5'-nucleotidase, cytosolic III
chr3_-_121944040 0.396


chr13_-_72253970 0.396 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr5_+_88220846 0.394


chr14_-_20642214 0.393


chr15_+_63948823 0.392 NM_004663
RAB11A
RAB11A, member RAS oncogene family
chr13_+_44461657 0.391 NM_018559
KIAA1704
KIAA1704
chr2_-_20114761 0.390 LAPTM4A
lysosomal protein transmembrane 4 alpha
chr2_-_100400481 0.390 NM_004854
CHST10
carbohydrate sulfotransferase 10
chr17_-_46553083 0.386 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr17_+_43165608 0.385 NM_013351
TBX21
T-box 21
chr6_+_126112506 0.385 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr2_-_202216451 0.384 NM_001044385
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr17_-_13445942 0.383 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr17_-_38229790 0.383 NM_003766
BECN1
beclin 1, autophagy related
chr10_-_127574957 0.383 DHX32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr12_+_48026955 0.382 DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr17_+_40581617 0.382 HEXIM1
hexamethylene bis-acetamide inducible 1
chr3_+_50687675 0.381 NM_004947
DOCK3
dedicator of cytokinesis 3
chr19_-_16599986 0.378 NM_004831
MED26
mediator complex subunit 26
chr2_+_74595073 0.378 NM_016170
TLX2
T-cell leukemia homeobox 2
chr2_+_223433919 0.376 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr16_+_69115227 0.371 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr9_+_134895882 0.371 NM_001122823
NM_012087
GTF3C5

general transcription factor IIIC, polypeptide 5, 63kDa

chr16_+_166678 0.370 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr12_+_56406296 0.370 LOC100130776
hypothetical LOC100130776
chr3_+_148609841 0.368 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chrX_+_128942435 0.368


chr20_-_35589496 0.367 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr16_+_69115225 0.367 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr20_-_1395463 0.365 NSFL1C
NSFL1 (p97) cofactor (p47)
chr2_-_196641682 0.364 NM_018897
DNAH7
dynein, axonemal, heavy chain 7
chr6_+_117305068 0.363 NM_173560
RFX6
regulatory factor X, 6
chr4_+_57066131 0.361 NM_206919
ARL9
ADP-ribosylation factor-like 9
chr22_-_40414765 0.360 NM_001003796
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr10_-_102978678 0.359 NM_006562
LBX1
ladybird homeobox 1
chr6_+_1335067 0.359 NM_001452
FOXF2
forkhead box F2
chr2_-_38683119 0.358 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr2_-_241408296 0.357 NM_004321
KIF1A
kinesin family member 1A
chr13_-_72254071 0.356 NM_001128226
NM_014953
DIS3

DIS3 mitotic control homolog (S. cerevisiae)

chr12_-_100748640 0.355 NM_024312
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr15_-_37999717 0.353 GPR176
G protein-coupled receptor 176
chr6_+_99389318 0.352 POU3F2
POU class 3 homeobox 2
chr13_+_44592585 0.351 NM_004128
GTF2F2
general transcription factor IIF, polypeptide 2, 30kDa
chr18_-_11138760 0.349 NM_022068
FAM38B
family with sequence similarity 38, member B
chr11_+_24475091 0.349 NM_001009909
LUZP2
leucine zipper protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
425.69 1.02e-03 GO:0060040 retinal bipolar neuron differentiation
163.76 7.92e-03 GO:0003407 neural retina development
118.29 1.55e-02 GO:0060042 retina morphogenesis in camera-type eye

Nothing significant found in compartment category.

Nothing significant found in function category.