Motif ID: GFI1.p2

Z-value: 1.221


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor



Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_22860547 1.560 PABPN1
poly(A) binding protein, nuclear 1
chr14_+_22860511 1.153 PABPN1
poly(A) binding protein, nuclear 1
chr6_-_26358811 1.118 NM_021018
HIST1H3F
histone cluster 1, H3f
chr19_-_59355246 1.074 NM_024316
LENG1
leukocyte receptor cluster (LRC) member 1
chr18_+_12981329 1.056 NM_032142
CEP192
centrosomal protein 192kDa
chr6_-_33028790 1.017 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr6_+_26359805 0.942 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr11_-_95715976 0.933 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr6_+_26153590 0.930 NM_003531
HIST1H3C
histone cluster 1, H3c
chr12_-_28016182 0.923 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr9_+_91115924 0.922 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr5_+_66160359 0.919 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_67628523 0.911 FLJ37644
hypothetical LOC400618
chr1_-_152162074 0.891 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr17_-_57295451 0.872 NM_032043
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr4_+_148757958 0.869 NM_018241
TMEM184C
transmembrane protein 184C
chr7_-_148356433 0.836 PDIA4
protein disulfide isomerase family A, member 4
chr6_-_27208507 0.824 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr17_+_43328514 0.819 NM_003110
SP2
Sp2 transcription factor
chr8_+_66719441 0.788 NM_001145839
NM_014637
MTFR1

mitochondrial fission regulator 1

chr6_-_26379567 0.779 NM_003534
HIST1H3G
histone cluster 1, H3g
chr6_-_30289092 0.779 NM_003449
TRIM26
tripartite motif containing 26
chr3_+_173951163 0.749 ECT2
epithelial cell transforming sequence 2 oncogene
chr12_+_56374004 0.749 NM_001017956
NM_001017957
NM_001017958
NM_006812
OS9



osteosarcoma amplified 9, endoplasmic reticulum lectin



chr17_+_56109940 0.748 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr4_+_147316284 0.748 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_57835028 0.741 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr6_-_26343139 0.730 NM_005320
HIST1H1D
histone cluster 1, H1d
chr3_+_123817151 0.729 NM_152615
PARP15
poly (ADP-ribose) polymerase family, member 15
chr3_+_112876212 0.727 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr14_+_57834962 0.727 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr8_-_28403652 0.725 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr21_-_42789369 0.725 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr4_+_166468266 0.723 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr20_+_254205 0.718 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr14_-_23680581 0.703 NM_016049
FAM158A
family with sequence similarity 158, member A
chr4_+_148758014 0.694 TMEM184C
transmembrane protein 184C
chr15_+_39032927 0.692 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr17_-_35827568 0.685 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr7_-_30510849 0.683 NM_024051
GGCT
gamma-glutamylcyclotransferase
chr6_-_33016561 0.678 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_-_172675873 0.665 DLX2
distal-less homeobox 2
chr2_+_198026470 0.661 NM_025147
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr2_-_85969527 0.659 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_+_48003237 0.658 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr17_+_73694992 0.638 NM_001010982
NM_001145526
AFMID

arylformamidase

chr20_-_54400628 0.632 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr6_+_33530297 0.626 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr12_+_52733927 0.625 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr9_+_130883199 0.619 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr14_+_23654307 0.613 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr20_+_29790564 0.609 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr2_-_88707978 0.605 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr5_+_140709907 0.603 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr6_-_136613097 0.602 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr11_-_117640407 0.601 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr14_-_30959487 0.599 HEATR5A
HEAT repeat containing 5A
chr17_-_71287417 0.594 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr2_-_69033515 0.592 NM_182536
GKN2
gastrokine 2
chr17_+_40581617 0.591 HEXIM1
hexamethylene bis-acetamide inducible 1
chr16_-_19440786 0.581 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr1_+_144149794 0.570 NM_006472
TXNIP
thioredoxin interacting protein
chr8_-_103737058 0.570 NM_005655
KLF10
Kruppel-like factor 10
chr14_-_20807346 0.569 NM_001077442
NM_001077443
NM_004500
NM_031314
HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr11_+_17254854 0.569 NM_005013
NUCB2
nucleobindin 2
chr17_+_31160550 0.566 NM_003487
NM_139215
TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

chr11_-_47154955 0.565 NM_032389
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr2_+_183651531 0.550 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr2_-_175741096 0.549 NM_001880
ATF2
activating transcription factor 2
chr16_+_8675904 0.547 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr6_-_18372617 0.541 NM_001134709
NM_003472
DEK

DEK oncogene

chr6_+_46728590 0.540 NM_004277
SLC25A27
solute carrier family 25, member 27
chr6_-_26140266 0.539 NM_003537
HIST1H3B
histone cluster 1, H3b
chr11_-_8849485 0.526 ST5
suppression of tumorigenicity 5
chr17_+_43082557 0.523 KPNB1
karyopherin (importin) beta 1
chr17_-_73694669 0.521 NM_003258
TK1
thymidine kinase 1, soluble
chr12_+_27568311 0.515 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr1_+_28458546 0.515 NM_031459
SESN2
sestrin 2
chr17_+_40581704 0.513 HEXIM1
hexamethylene bis-acetamide inducible 1
chr1_+_25629968 0.504 NM_018202
TMEM57
transmembrane protein 57
chr6_-_26305456 0.502 HIST1H3D
histone cluster 1, H3d
chr16_+_55777739 0.502 NM_133368
RSPRY1
ring finger and SPRY domain containing 1
chr2_+_85676347 0.501 NM_016494
RNF181
ring finger protein 181
chr6_+_31538934 0.501 NM_006674
HCP5
HLA complex P5
chr6_+_132000134 0.500 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_+_96672705 0.499 MBNL2
muscleblind-like 2 (Drosophila)
chr7_+_133982070 0.499 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr1_-_109307539 0.498 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr2_+_172658453 0.498 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr2_-_96237665 0.497 STARD7
StAR-related lipid transfer (START) domain containing 7
chr10_-_32707549 0.493 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr6_-_53321545 0.491 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr12_+_49728350 0.484 NM_001024668
NM_015416
LETMD1

LETM1 domain containing 1

chr12_-_56200547 0.484 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr2_-_211049619 0.481 NM_001136574
NM_006055
NM_001136575
LANCL1


LanC lantibiotic synthetase component C-like 1 (bacterial)


chr6_+_32515596 0.480 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr6_-_169395847 0.478 THBS2
thrombospondin 2
chr6_-_10520264 0.477 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_-_53849929 0.477 NM_017763
RNF43
ring finger protein 43
chr6_-_27943287 0.472 NM_005322
HIST1H1B
histone cluster 1, H1b
chr5_-_64894687 0.471 NM_022145
CENPK
centromere protein K
chr1_+_144188375 0.470 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr17_+_67628749 0.469 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr2_+_62786290 0.468 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr20_-_45418818 0.466 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr19_-_51319769 0.465 NM_207393
IGFL3
IGF-like family member 3
chr15_-_41000100 0.462 NM_173500
TTBK2
tau tubulin kinase 2
chr2_-_42441798 0.457 NM_004718
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr9_-_124733599 0.456 NM_020924
ZBTB26
zinc finger and BTB domain containing 26
chr20_+_2030527 0.456 NM_080836
STK35
serine/threonine kinase 35
chr6_+_89848229 0.453 PNRC1
proline-rich nuclear receptor coactivator 1
chr17_-_43977273 0.449 NM_002145
HOXB2
homeobox B2
chr10_+_102123589 0.448 NCRNA00263
non-protein coding RNA 263
chr6_+_21701942 0.448 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr10_-_64698831 0.447 NM_004241
JMJD1C
jumonji domain containing 1C
chr2_-_130603264 0.446 NM_001099771
POTEF
POTE ankyrin domain family, member F
chr15_+_67532176 0.445 NM_001003
NM_213725
RPLP1

ribosomal protein, large, P1

chr1_-_55002748 0.442 NM_152268
PARS2
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr22_-_35502059 0.441 NM_001177701
NM_006860
IFT27

intraflagellar transport 27 homolog (Chlamydomonas)

chr4_+_167013859 0.440 NM_012464
TLL1
tolloid-like 1
chr3_-_168935287 0.440 NM_007217
NM_145860
NM_145859
PDCD10


programmed cell death 10


chr17_+_67628763 0.439 SOX9
SRY (sex determining region Y)-box 9
chr14_-_81069951 0.438 NM_005065
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr3_+_132583204 0.434 NM_001171905
NM_001171906
NM_152395
NUDT16


nudix (nucleoside diphosphate linked moiety X)-type motif 16


chr17_-_45427565 0.434 NM_005220
DLX3
distal-less homeobox 3
chr3_+_63928459 0.434 NM_001128149
ATXN7
ataxin 7
chr6_-_161614962 0.434 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr16_+_51722285 0.431 CHD9
chromodomain helicase DNA binding protein 9
chr15_+_87919744 0.431 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr1_+_85300580 0.430 NM_145172
WDR63
WD repeat domain 63
chr18_+_42780784 0.427 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr20_+_54401099 0.425 NM_001033522
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr10_-_62002672 0.424 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_+_10787328 0.422


chr5_-_110876186 0.421 STARD4
StAR-related lipid transfer (START) domain containing 4
chr6_-_26164478 0.421 NM_005319
HIST1H1C
histone cluster 1, H1c
chr6_+_26381122 0.420 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr15_+_83724743 0.420 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr4_+_183302105 0.419 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr20_-_39680405 0.419 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr2_-_219404755 0.415 NM_017431
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr21_+_43186428 0.415 NM_001001503
NM_021075
NDUFV3

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

chr2_-_153282104 0.413 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr1_+_34997928 0.412 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr7_+_91996022 0.410 NM_032120
C7orf64
chromosome 7 open reading frame 64
chr2_+_242679507 0.410 LOC728323
hypothetical LOC728323
chr17_+_24071117 0.408 NM_000984
RPL23A
ribosomal protein L23a
chr2_-_38956496 0.406 NM_198963
DHX57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
chr2_+_74539039 0.405 NM_012477
WBP1
WW domain binding protein 1
chr6_+_36752244 0.402 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr20_-_5539487 0.399 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_-_97646758 0.399 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr2_-_113238638 0.398 NM_152515
CKAP2L
cytoskeleton associated protein 2-like
chr1_-_109386112 0.396 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chr1_-_148936123 0.396 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr2_-_71307705 0.395 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr11_-_47154996 0.392 ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr6_+_35856798 0.391 NM_001010886
C6orf127
chromosome 6 open reading frame 127
chr11_+_43658718 0.387 NM_016142
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr6_+_114285209 0.386 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr14_-_22693333 0.384 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr13_+_59868591 0.384 NM_001146071
NM_030794
TDRD3

tudor domain containing 3

chr2_-_74259308 0.384 NM_018221
MOBKL1B
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr13_+_97426713 0.382 IPO5
importin 5
chr5_+_64894854 0.381 NM_015342
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr14_-_22468393 0.381 PRMT5
protein arginine methyltransferase 5
chr17_-_41794825 0.381 NM_001039083
NM_001103154
ARL17A
ARL17B

ADP-ribosylation factor-like 17A
ADP-ribosylation factor-like 17B

chr2_-_176575171 0.380 NM_030650
KIAA1715
KIAA1715
chr11_+_71317736 0.377 RNF121
ring finger protein 121
chr11_-_85074848 0.375 NM_152723
CCDC89
coiled-coil domain containing 89
chr6_-_26324850 0.375 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr2_-_152538694 0.375 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_-_150109324 0.373 NM_198887
NUP43
nucleoporin 43kDa
chr20_+_32755778 0.372 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_-_36181927 0.372 NM_181539
KRT26
keratin 26
chr11_-_22603905 0.370 NM_022725
FANCF
Fanconi anemia, complementation group F
chr6_+_27885692 0.369 NM_003536
HIST1H3H
histone cluster 1, H3h
chr20_+_47096280 0.367 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr17_-_43328141 0.365


chr1_-_144538285 0.365 NM_001097612
NM_001097613
GPR89B
GPR89A

G protein-coupled receptor 89B
G protein-coupled receptor 89A

chr7_-_104440707 0.365 LOC100216545
hypothetical LOC100216545
chr2_+_38956606 0.364 NM_001145450
MORN2
MORN repeat containing 2
chr13_+_96672541 0.362 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr14_+_101346032 0.360 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr19_-_2901583 0.360


chr16_+_15651583 0.360 NM_017668
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr11_-_2677799 0.357 KCNQ1OT1
KCNQ1 overlapping transcript 1 (non-protein coding)
chr1_-_68735267 0.356 DEPDC1
DEP domain containing 1
chr11_-_27341251 0.356 NM_030771
NM_080654
CCDC34

coiled-coil domain containing 34

chr17_+_31975611 0.355 GGNBP2
gametogenetin binding protein 2
chr5_-_112658200 0.354 MCC
mutated in colorectal cancers
chr17_+_54587882 0.354 PRR11
proline rich 11
chr11_-_129377889 0.353 PRDM10
PR domain containing 10
chr6_+_160131472 0.352 NM_014161
MRPL18
mitochondrial ribosomal protein L18
chr2_+_183651713 0.350 DUSP19
dual specificity phosphatase 19
chr7_-_150555153 0.349 NM_005692
NM_007189
ABCF2

ATP-binding cassette, sub-family F (GCN20), member 2

chr6_+_26325124 0.348 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr1_+_109036431 0.346 NM_018061
PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr20_+_31083111 0.345 NM_174897
BPIL3
bactericidal/permeability-increasing protein-like 3
chr1_+_165565006 0.343 POU2F1
POU class 2 homeobox 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.