Motif ID: GLI1..3.p2

Z-value: 1.430


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3



Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_19691397 1.544 NM_145117
NM_182964
NAV2

neuron navigator 2

chr7_-_107883929 1.342 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr5_+_71438796 1.312 NM_005909
MAP1B
microtubule-associated protein 1B
chr16_+_85169615 1.300 NM_005250
FOXL1
forkhead box L1
chr22_+_18090118 1.266 SEPT5-GP1BB
SEPT5-GP1BB read-through transcript
chr14_+_76298693 1.049 VASH1
vasohibin 1
chr14_+_76297885 0.998 NM_014909
VASH1
vasohibin 1
chr4_-_140696740 0.900 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr4_+_134289893 0.882 NM_020815
NM_032961
PCDH10

protocadherin 10

chr2_+_109112428 0.855 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr5_+_175725050 0.821 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr5_+_92946348 0.818 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_75854281 0.810 SLC44A5
solute carrier family 44, member 5
chr19_+_10404110 0.804 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr9_+_130909926 0.796


chr11_+_56705796 0.779 NM_001005210
LRRC55
leucine rich repeat containing 55
chr10_+_31650069 0.771 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr17_-_3321782 0.737 NM_032598
NM_001170699
NM_001170698
NM_001170697
NM_001170695
NM_001170696
SPATA22





spermatogenesis associated 22





chr22_-_17892001 0.721 CLDN5
claudin 5
chr2_+_128119908 0.707 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr11_-_118693021 0.701 NM_006500
MCAM
melanoma cell adhesion molecule
chr5_-_168204430 0.694


chr1_-_24307514 0.679 MYOM3
myomesin family, member 3
chr11_+_76491532 0.672 NM_006189
OMP
olfactory marker protein
chr12_-_3732478 0.670 EFCAB4B
EF-hand calcium binding domain 4B
chr11_+_1897374 0.666 NM_001042780
NM_001042781
NM_001042782
NM_006757
TNNT3



troponin T type 3 (skeletal, fast)



chr12_-_3732614 0.657 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr22_-_35835548 0.648 TMPRSS6
transmembrane protease, serine 6
chr1_+_3597092 0.644 NM_001126240
NM_001126241
NM_001126242
TP73


tumor protein p73


chr19_+_16296632 0.625 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr11_-_404975 0.619 NM_001135054
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr18_+_58143499 0.613 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr2_+_242460553 0.611 NM_173821
C2orf85
chromosome 2 open reading frame 85
chr14_+_99181232 0.610 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr3_+_155321826 0.608 NM_015595
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr22_-_17891777 0.607 CLDN5
claudin 5
chr17_-_3740785 0.606 NM_172206
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr12_+_79625538 0.605 NM_002469
MYF6
myogenic factor 6 (herculin)
chr3_-_38666122 0.592 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr3_+_50272648 0.591


chr2_-_26058831 0.589 KIF3C
kinesin family member 3C
chr11_+_122806196 0.587 LOC100128242
hypothetical LOC100128242
chr5_-_1165106 0.586 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr1_+_43837096 0.586 PTPRF
protein tyrosine phosphatase, receptor type, F
chr5_+_176170041 0.575 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr19_+_14405216 0.564 PKN1
protein kinase N1
chr7_+_129918408 0.561 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr1_+_9275542 0.559 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr22_+_43442987 0.559 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr9_+_130056513 0.555


chr20_-_44612619 0.553 NM_080721
C20orf123
chromosome 20 open reading frame 123
chr6_-_168222645 0.552 NM_024919
FRMD1
FERM domain containing 1
chr17_-_17340219 0.551 NM_016084
RASD1
RAS, dexamethasone-induced 1
chr13_+_112789669 0.549 MCF2L
MCF.2 cell line derived transforming sequence-like
chr14_-_51605515 0.539 NID2
nidogen 2 (osteonidogen)
chr21_-_31175722 0.532 NM_175858
KRTAP11-1
keratin associated protein 11-1
chr14_-_51605487 0.530 NID2
nidogen 2 (osteonidogen)
chr1_-_152202574 0.528 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr2_-_175578156 0.527 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr1_-_32036802 0.527 SPOCD1
SPOC domain containing 1
chr22_+_18388633 0.525 C22orf25
chromosome 22 open reading frame 25
chr22_+_18388656 0.521 C22orf25
chromosome 22 open reading frame 25
chr5_-_132189762 0.517 NM_133456
SHROOM1
shroom family member 1
chr7_-_130891861 0.515 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr16_+_85158357 0.510 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr14_-_51605461 0.507 NID2
nidogen 2 (osteonidogen)
chr16_+_55456619 0.504 NM_000339
NM_001126107
NM_001126108
SLC12A3


solute carrier family 12 (sodium/chloride transporters), member 3


chrX_+_100361588 0.503 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr3_+_39826032 0.502 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr10_+_685887 0.502 C10orf108
chromosome 10 open reading frame 108
chr11_-_1007140 0.498 MUC6
mucin 6, oligomeric mucus/gel-forming
chr11_+_1848674 0.497 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr8_+_21972804 0.495 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr17_+_42686248 0.493


chr17_+_42686153 0.488 NM_000212
ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr14_-_51605695 0.487 NM_007361
NID2
nidogen 2 (osteonidogen)
chr15_+_67378326 0.486 NM_017705
PAQR5
progestin and adipoQ receptor family member V
chr18_-_42810446 0.478 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr12_-_111304138 0.477 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr7_-_150515851 0.470 NM_080871
ASB10
ankyrin repeat and SOCS box containing 10
chr7_+_27191534 0.470 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr1_-_45081190 0.469 NM_001166292
NM_003738
PTCH2

patched 2

chr19_-_44158130 0.464 NM_024907
FBXO17
F-box protein 17
chrX_-_114374860 0.464 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr2_+_42129440 0.463


chr19_+_14405100 0.457 NM_002741
PKN1
protein kinase N1
chr5_+_122452739 0.455 NM_001136239
PRDM6
PR domain containing 6
chrX_+_115481848 0.454 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr3_+_160964574 0.451 SCHIP1
schwannomin interacting protein 1
chr17_-_74432671 0.450 TIMP2
TIMP metallopeptidase inhibitor 2
chr2_+_54537842 0.450 SPTBN1
spectrin, beta, non-erythrocytic 1
chr16_+_87021379 0.448 NM_001127464
ZNF469
zinc finger protein 469
chr22_+_45401321 0.448 NM_015124
GRAMD4
GRAM domain containing 4
chr12_+_50586958 0.446 ACVRL1
activin A receptor type II-like 1
chr19_-_59676153 0.446 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr13_+_112808102 0.446 NM_000131
NM_019616
F7

coagulation factor VII (serum prothrombin conversion accelerator)

chr22_+_18388602 0.445 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr3_+_44601457 0.443 NM_173658
ZNF660
zinc finger protein 660
chr11_-_60880799 0.440 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr20_+_60558104 0.437 NM_178463
C20orf166
chromosome 20 open reading frame 166
chr2_-_20075929 0.435 NM_002381
MATN3
matrilin 3
chr17_-_74432800 0.431 TIMP2
TIMP metallopeptidase inhibitor 2
chrX_+_13581145 0.430 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr19_+_16296734 0.429 KLF2
Kruppel-like factor 2 (lung)
chr16_+_56259657 0.429 NM_170776
GPR97
G protein-coupled receptor 97
chrX_-_16798363 0.427 RBBP7
retinoblastoma binding protein 7
chr2_-_133144094 0.422 LYPD1
LY6/PLAUR domain containing 1
chr17_+_42686217 0.418 ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr18_-_42810206 0.417 NM_001100817
TCEB3C
TCEB3CL
transcription elongation factor B polypeptide 3C (elongin A3)
transcription elongation factor B polypeptide 3C-like
chr14_+_105012106 0.412 NM_001312
CRIP2
cysteine-rich protein 2
chr3_-_130761967 0.411 PLXND1
plexin D1
chr9_-_138757175 0.407 NM_001001712
LCN10
lipocalin 10
chrX_-_52700674 0.405 NM_173358
SSX7
synovial sarcoma, X breakpoint 7
chr5_+_161427225 0.405 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr18_-_42798364 0.404 NM_001100817
TCEB3C
TCEB3CL
transcription elongation factor B polypeptide 3C (elongin A3)
transcription elongation factor B polypeptide 3C-like
chr20_-_36191623 0.400 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr16_-_16224791 0.397 NM_001079528
NM_001171
ABCC6

ATP-binding cassette, sub-family C (CFTR/MRP), member 6

chr11_-_1006736 0.394 MUC6
mucin 6, oligomeric mucus/gel-forming
chr17_+_7264366 0.394 NM_199339
SPEM1
spermatid maturation 1
chr7_-_100262971 0.392 NM_004444
EPHB4
EPH receptor B4
chr19_+_3490154 0.390 NM_001135580
C19orf71
chromosome 19 open reading frame 71
chr19_+_48610874 0.389 NM_001130011
TEX101
testis expressed 101
chrX_-_34585287 0.388 NM_031442
TMEM47
transmembrane protein 47
chr18_-_42804531 0.387 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chrX_-_16798383 0.384 NM_002893
RBBP7
retinoblastoma binding protein 7
chr15_+_72253940 0.383 NM_201526
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr13_+_56613052 0.382 NM_198441
NM_001130404
NM_001130405
NM_001130406
NM_001130407
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
proline rich 20A
proline rich 20B
proline rich 20C
proline rich 20D
proline rich 20E
chr15_+_65217412 0.379 NM_001145103
SMAD3
SMAD family member 3
chr2_-_20075889 0.377 MATN3
matrilin 3
chr1_-_45862225 0.372 NM_001114938
NM_001190182
CCDC17

coiled-coil domain containing 17

chr2_-_192767844 0.371 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chrX_-_43717864 0.371 NM_000266
NDP
Norrie disease (pseudoglioma)
chr12_-_6668880 0.370 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr6_+_136214495 0.368 NM_018945
PDE7B
phosphodiesterase 7B
chr12_-_4425040 0.366 NM_020996
FGF6
fibroblast growth factor 6
chr7_-_27191287 0.364 NM_005523
HOXA11
homeobox A11
chr12_+_50587468 0.361 NM_000020
ACVRL1
activin A receptor type II-like 1
chr3_+_138020550 0.359 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr19_+_659766 0.358 NM_001040134
NM_002579
PALM

paralemmin

chr6_-_3697244 0.357 NM_183373
C6orf145
chromosome 6 open reading frame 145
chr7_-_100009205 0.356 NM_001168682
SAP25
sin3A-binding protein 25
chr12_-_117026038 0.355 NM_019086
VSIG10
V-set and immunoglobulin domain containing 10
chr6_+_3697328 0.354


chr2_-_144991556 0.354 ZEB2
zinc finger E-box binding homeobox 2
chrX_+_115481774 0.350 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr9_+_89302239 0.348 DAPK1
death-associated protein kinase 1
chrX_-_135941498 0.348 NM_054021
GPR101
G protein-coupled receptor 101
chrX_+_111212908 0.343 NM_001004308
ZCCHC16
zinc finger, CCHC domain containing 16
chr14_+_95222506 0.341 NM_004918
NM_199206
TCL1B

T-cell leukemia/lymphoma 1B

chr7_-_4889772 0.341 NM_018059
RADIL
Ras association and DIL domains
chr17_+_15788955 0.341 NM_000676
ADORA2B
adenosine A2b receptor
chr1_+_1256585 0.340 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr15_+_37660568 0.339 NM_003246
THBS1
thrombospondin 1
chr1_-_159099090 0.339 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chrX_-_47394808 0.335 ELK1
ELK1, member of ETS oncogene family
chr8_+_21972631 0.333 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr1_+_22224571 0.333 HSPC157
hypothetical LOC29092
chr19_-_53516962 0.332 CCDC114
coiled-coil domain containing 114
chr5_-_149515331 0.329 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr11_-_3035172 0.328 NM_001014437
NM_001194997
NM_001751
NM_139273
CARS



cysteinyl-tRNA synthetase



chr4_-_164614335 0.326 NM_032136
TKTL2
transketolase-like 2
chrX_+_52797004 0.326 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chr17_+_4348877 0.325 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr18_+_2896956 0.322 EMILIN2
elastin microfibril interfacer 2
chr1_+_152566899 0.322 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr7_+_94130752 0.322 PEG10
paternally expressed 10
chr21_+_44534575 0.321 NM_000658
AIRE
autoimmune regulator
chrX_-_52752935 0.321 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chr7_-_27180398 0.320 NM_018951
HOXA10
homeobox A10
chr17_-_44641741 0.320 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr5_+_175017705 0.320 HRH2
histamine receptor H2
chr10_+_5556923 0.320 NM_005185
CALML3
calmodulin-like 3
chr18_+_2896178 0.320 EMILIN2
elastin microfibril interfacer 2
chr19_-_15436333 0.319 NM_022904
RASAL3
RAS protein activator like 3
chr15_-_76720598 0.319 NM_000750
CHRNB4
cholinergic receptor, nicotinic, beta 4
chr15_+_67393795 0.318 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chr17_+_4795128 0.318 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr1_+_148090804 0.314 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr3_+_47004457 0.312 NBEAL2
neurobeachin-like 2
chr8_-_86762977 0.311 NM_172239
REXO1L1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1
chr12_-_131256525 0.311 NM_021808
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr16_+_87232501 0.309 NM_013278
IL17C
interleukin 17C
chr11_-_45643711 0.309 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr2_-_80384454 0.307 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr1_+_1104939 0.307 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chrX_+_151837064 0.307 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr2_+_131692393 0.306 NM_001083538
POTEE
POTE ankyrin domain family, member E
chr7_+_68702252 0.306 AUTS2
autism susceptibility candidate 2
chr5_+_176449156 0.306 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr22_+_38090120 0.303 NM_145738
SYNGR1
synaptogyrin 1
chr1_-_151784889 0.302 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr11_-_27677755 0.301 NM_170734
BDNF
brain-derived neurotrophic factor
chrX_+_101792949 0.300 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr5_-_37285160 0.297 NM_023073
C5orf42
chromosome 5 open reading frame 42
chrX_+_90576252 0.296 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr6_-_166960690 0.295 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_+_51944658 0.294 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr1_+_43539239 0.293 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr5_-_156935317 0.290 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr9_-_114692782 0.289 NM_033051
SLC46A2
solute carrier family 46, member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
177.51 2.59e-03 GO:0007416 synapse assembly
177.51 2.59e-03 GO:0030516 regulation of axon extension
177.51 2.59e-03 GO:0045666 positive regulation of neuron differentiation
30.04 3.47e-03 GO:0022603 regulation of anatomical structure morphogenesis
109.30 6.92e-03 GO:0050808 synapse organization
82.41 1.22e-02 GO:0050770 regulation of axonogenesis
81.24 1.26e-02 GO:0048638 regulation of developmental growth
18.59 1.46e-02 GO:0007417 central nervous system development
57.49 2.52e-02 GO:0021700 developmental maturation
47.46 3.69e-02 GO:0010975 regulation of neuron projection development
46.68 3.82e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
46.30 3.88e-02 GO:0022604 regulation of cell morphogenesis
46.30 3.88e-02 GO:0051789 response to protein stimulus
12.72 4.53e-02 GO:2000026 regulation of multicellular organismal development

Nothing significant found in compartment category.

Nothing significant found in function category.