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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 4.741

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_1704661	8.285	NM_001080488	ONECUT3	one cut homeobox 3
chr9_+_94987032	8.071	NM_006648	WNK2	WNK lysine deficient protein kinase 2
chr12_-_131415854	7.967	NM_001122636	GALNT9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr5_+_76542461	6.954	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr18_+_74841262	6.765	NM_171999	SALL3	sal-like 3 (Drosophila)
chr16_+_162845	6.440	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr18_-_68361742	6.277		CBLN2	cerebellin 2 precursor
chr2_-_233501069	6.053	NM_001114090	NGEF	neuronal guanine nucleotide exchange factor
chr19_+_659766	5.649	NM_001040134 NM_002579	PALM	paralemmin
chr7_+_154943466	5.640	NM_001427	EN2	engrailed homeobox 2
chr11_+_359723	5.600	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr10_-_103525646	5.418	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr15_-_27650218	5.358	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr15_-_49174107	5.298		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr7_-_44331544	5.243	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr22_+_47263919	5.230	NM_001082967	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr8_+_1937711	5.118		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr4_-_41848874	4.992		BEND4	BEN domain containing 4
chr4_+_3737872	4.953		ADRA2C	adrenergic, alpha-2C-, receptor
chr4_-_174687104	4.892		HAND2	heart and neural crest derivatives expressed 2
chr9_+_17568952	4.831	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr20_-_61933012	4.830		ZBTB46	zinc finger and BTB domain containing 46
chr3_-_130807865	4.815	NM_015103	PLXND1	plexin D1
chr1_-_6162669	4.764	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr6_+_159510416	4.752	NM_032532	FNDC1	fibronectin type III domain containing 1
chr10_+_23521464	4.695	NM_178161	PTF1A	pancreas specific transcription factor, 1a
chr10_-_132999798	4.673		TCERG1L	transcription elongation regulator 1-like
chr19_+_1236766	4.649	NM_001405	EFNA2	ephrin-A2
chr14_+_103621768	4.637	NM_001080464	ASPG	asparaginase homolog (S. cerevisiae)
chr14_+_104402626	4.584	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr12_+_127317900	4.550	NM_001136103	TMEM132C	transmembrane protein 132C
chr16_+_82559600	4.546	NM_019065	NECAB2	N-terminal EF-hand calcium binding protein 2
chr19_+_540849	4.460	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr6_+_137285071	4.432	NM_001008783	SLC35D3	solute carrier family 35, member D3
chr10_-_132999973	4.347	NM_174937	TCERG1L	transcription elongation regulator 1-like
chr4_+_2031036	4.307	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr16_-_2186465	4.242	NM_020764	CASKIN1	CASK interacting protein 1
chr12_+_131705438	4.221	NM_012226 NM_016318 NM_170682 NM_170683 NM_174872 NM_174873	P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2
chr17_-_10042579	4.186	NM_201433	GAS7	growth arrest-specific 7
chr9_+_123501186	4.164		DAB2IP	DAB2 interacting protein
chrX_+_72140076	4.109	NM_001042506	PABPC1L2B	poly(A) binding protein, cytoplasmic 1-like 2B
chr22_-_45037882	4.083	NM_006071	PKDREJ	polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr14_+_91859904	4.068	NM_153646	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr22_-_43784093	4.064	NM_138415	PHF21B	PHD finger protein 21B
chr1_-_111019148	4.059	NM_002232	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3
chr3_+_53504070	3.969	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr2_-_238813284	3.962		HES6	hairy and enhancer of split 6 (Drosophila)
chr4_-_110443247	3.878	NM_032518 NM_198721	COL25A1	collagen, type XXV, alpha 1
chr1_+_226261374	3.876	NM_033131	WNT3A	wingless-type MMTV integration site family, member 3A
chr1_-_62557559	3.793		KANK4	KN motif and ankyrin repeat domains 4
chr1_-_202921103	3.779	NM_006338 NM_201630	LRRN2	leucine rich repeat neuronal 2
chr19_-_411995	3.778	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr18_+_65219114	3.770	NM_152721	DOK6	docking protein 6
chr11_-_110088330	3.768	NM_020809	ARHGAP20	Rho GTPase activating protein 20
chrX_+_147389825	3.765	NM_001169122 NM_001169123 NM_001169124 NM_001169125 NM_002025	AFF2	AF4/FMR2 family, member 2
chr4_-_174686918	3.704		HAND2	heart and neural crest derivatives expressed 2
chr14_+_105012106	3.698	NM_001312	CRIP2	cysteine-rich protein 2
chr10_-_99521701	3.683	NM_003015	SFRP5	secreted frizzled-related protein 5
chr12_+_107047594	3.618	NM_014653	WSCD2	WSC domain containing 2
chr14_+_101097440	3.615	NM_001362	DIO3	deiodinase, iodothyronine, type III
chr15_-_20666684	3.607		LOC283683	hypothetical LOC283683
chr22_+_48951286	3.603	NM_001160300 NM_052839	PANX2	pannexin 2
chr1_-_111019051	3.603
chr11_-_110088097	3.590		ARHGAP20	Rho GTPase activating protein 20
chr1_+_237616457	3.570		CHRM3	cholinergic receptor, muscarinic 3
chr18_-_55091596	3.563	NM_013435	RAX	retina and anterior neural fold homeobox
chr22_+_38183480	3.559		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr19_-_15204194	3.512	NM_024794	EPHX3	epoxide hydrolase 3
chr16_+_88169612	3.497	NM_014427 NM_153636	CPNE7	copine VII
chr4_+_48180033	3.492	NM_152679	SLC10A4	solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr11_+_119887630	3.471		LOC100293636 GRIK4	hypothetical protein LOC100293636 glutamate receptor, ionotropic, kainate 4
chr13_+_32488477	3.381	NM_004795	KL	klotho
chr17_+_8865547	3.362	NM_004822	NTN1	netrin 1
chr18_-_42590989	3.350	NM_013305	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr12_+_108636569	3.298	NM_032829	C12orf34	chromosome 12 open reading frame 34
chr14_+_89597860	3.290	NM_022054	KCNK13	potassium channel, subfamily K, member 13
chr21_+_44594375	3.250		TRPM2	transient receptor potential cation channel, subfamily M, member 2
chr3_+_2115449	3.224		CNTN4	contactin 4
chr16_+_86194075	3.223		JPH3	junctophilin 3
chr13_+_95541093	3.216	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr5_-_11956964	3.202	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chrX_-_19443299	3.184	NM_001001671	MAP3K15	mitogen-activated protein kinase kinase kinase 15
chr7_+_128257698	3.173	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr13_-_94162249	3.128	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr1_+_226937732	3.102		RHOU	ras homolog gene family, member U
chr12_+_129212955	3.101	NM_007197	FZD10	frizzled homolog 10 (Drosophila)
chr1_-_62557655	3.075	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr7_-_131911808	3.072	NM_001105543 NM_020911	PLXNA4	plexin A4
chr22_-_37180958	3.063	NM_152868	KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4
chr18_-_5620629	3.051		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr15_+_31390454	3.050	NM_001036	RYR3	ryanodine receptor 3
chr18_+_53253775	3.046	NM_004852	ONECUT2	one cut homeobox 2
chr2_-_70848621	3.044	NM_001185055 NM_001617 NM_017482 NM_017488	ADD2	adducin 2 (beta)
chr11_+_1367665	3.043	NM_003957	BRSK2	BR serine/threonine kinase 2
chr2_-_238813365	3.035	NM_001142853 NM_018645	HES6	hairy and enhancer of split 6 (Drosophila)
chr20_-_54013418	3.003	NM_080617	CBLN4	cerebellin 4 precursor
chr9_+_138726737	2.992	NM_152421	FAM69B	family with sequence similarity 69, member B
chr11_-_6633427	2.988	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr14_+_91859289	2.985	NM_153647	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr4_+_3738093	2.983	NM_000683	ADRA2C	adrenergic, alpha-2C-, receptor
chr11_-_1549719	2.957	NM_004420	DUSP8	dual specificity phosphatase 8
chr3_-_50515857	2.942	NM_001005505 NM_001174051 NM_006030	CACNA2D2	calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr13_-_20193739	2.941
chr20_-_62151216	2.936	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr15_-_91433165	2.931	NM_020211	RGMA	RGM domain family, member A
chr17_+_19377732	2.925	NM_018242	SLC47A1	solute carrier family 47, member 1
chr1_-_50661716	2.915	NM_032110	DMRTA2	DMRT-like family A2
chr19_+_10402334	2.892	NM_001111308	PDE4A	phosphodiesterase 4A, cAMP-specific
chr22_-_37569679	2.880
chr15_-_81113676	2.875	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr22_+_28446288	2.864	NM_182527	CABP7	calcium binding protein 7
chr1_-_182273114	2.856		GLT25D2	glycosyltransferase 25 domain containing 2
chr7_-_4889772	2.849	NM_018059	RADIL	Ras association and DIL domains
chr10_+_116843108	2.842	NM_207303	ATRNL1	attractin-like 1
chr14_-_100104014	2.831	NM_001159531	BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)
chr18_-_6404900	2.824	NM_173464	L3MBTL4	l(3)mbt-like 4 (Drosophila)
chr1_+_63561632	2.798		FOXD3	forkhead box D3
chr7_+_98084531	2.789	NM_002523	NPTX2	neuronal pentraxin II
chr19_-_5291700	2.783	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr12_+_109956210	2.777	NM_015267	CUX2	cut-like homeobox 2
chr15_-_38362078	2.770	NM_001190479	LOC100131244	hypothetical protein LOC100131244
chr4_-_5940893	2.751		CRMP1	collapsin response mediator protein 1
chr3_+_71885890	2.741	NM_018971	GPR27	G protein-coupled receptor 27
chr16_+_2009741	2.739		NPW	neuropeptide W
chr15_+_39573363	2.738	NM_002220	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A
chr8_-_144583718	2.724	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr6_-_105691235	2.709	NM_007073	BVES	blood vessel epicardial substance
chr4_+_156349230	2.705	NM_000910	NPY2R	neuropeptide Y receptor Y2
chr17_-_77512346	2.688	NM_178493	NOTUM	notum pectinacetylesterase homolog (Drosophila)
chr3_+_12304332	2.679	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr14_+_72773957	2.664	NM_173462	NDRG2 PAPLN	NDRG family member 2 papilin, proteoglycan-like sulfated glycoprotein
chr9_-_135140450	2.653	NM_020469	ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr1_-_115682374	2.649	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr17_-_42411587	2.634	NM_203400	RPRML	reprimo-like
chr10_+_83625049	2.631	NM_001010848 NM_001165972	NRG3	neuregulin 3
chr1_+_22909916	2.631	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr14_+_51804180	2.626	NM_000953	PTGDR	prostaglandin D2 receptor (DP)
chr14_-_77034853	2.601	NM_182509 NM_199296	ISM2	isthmin 2 homolog (zebrafish)
chrX_+_9392980	2.598	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr17_+_5914364	2.594	NM_015253	WSCD1	WSC domain containing 1
chr22_-_37569962	2.577	NM_014293	NPTXR	neuronal pentraxin receptor
chr22_-_43783449	2.577		PHF21B	PHD finger protein 21B
chr12_-_128954164	2.577	NM_133448	TMEM132D	transmembrane protein 132D
chr2_+_120820140	2.576	NM_002193	INHBB	inhibin, beta B
chr9_+_140037863	2.560		CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr18_-_68685789	2.559	NM_138966	NETO1	neuropilin (NRP) and tolloid (TLL)-like 1
chr12_+_4788602	2.558	NM_002235	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6
chr1_+_41022066	2.549	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr11_-_27678551	2.531	NM_001143813 NM_001143814 NM_001709	BDNF	brain-derived neurotrophic factor
chr9_-_135140425	2.519		ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr3_+_141136691	2.512	NM_022131	CLSTN2	calsyntenin 2
chr3_-_129689394	2.511	NM_001145662	GATA2	GATA binding protein 2
chr19_-_18867868	2.505	NM_021267 NM_198207 NM_001492	LASS1 GDF1	LAG1 homolog, ceramide synthase 1 growth differentiation factor 1
chr16_+_166678	2.505	NM_000558	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr11_+_627268	2.502	NM_000797	DRD4	dopamine receptor D4
chr11_-_64268841	2.491	NM_001098670	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_-_4177519	2.476	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr10_+_112394094	2.473	NM_001134363	RBM20	RNA binding motif protein 20
chr4_-_1156362	2.472		SPON2	spondin 2, extracellular matrix protein
chr16_-_1908231	2.459	NM_001009606	HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr5_+_92946348	2.452		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr11_-_61104866	2.446	NM_004200	SYT7	synaptotagmin VII
chr4_+_156807311	2.431	NM_000856 NM_001130682 NM_001130686 NM_001130687 NM_001130683 NM_001130685	GUCY1A3	guanylate cyclase 1, soluble, alpha 3
chr18_-_4445247	2.421		DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chr16_+_86194170	2.411		JPH3	junctophilin 3
chr19_-_54267690	2.408		KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7
chr3_-_62835601	2.406
chr7_+_3307445	2.405	NM_152744	SDK1	sidekick homolog 1, cell adhesion molecule (chicken)
chr1_-_111018798	2.398		KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3
chr15_-_71448194	2.397		HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr3_-_199291938	2.381		LOC348840	hypothetical LOC348840
chr5_+_80292213	2.378		RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2
chr19_-_52614550	2.377	NM_001009813 NM_020160	MEIS3	Meis homeobox 3
chr6_-_110786167	2.375	NM_001123364	C6orf186	chromosome 6 open reading frame 186
chr12_-_129212720	2.374		FLJ31485	hypothetical LOC440119
chr6_-_84475211	2.363		SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr14_-_76677711	2.359		ZDHHC22	zinc finger, DHHC-type containing 22
chr19_-_1188840	2.354	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr19_-_52614280	2.353		MEIS3	Meis homeobox 3
chr17_-_1874927	2.339	NM_178568	RTN4RL1	reticulon 4 receptor-like 1
chr4_-_1156378	2.338		SPON2	spondin 2, extracellular matrix protein
chr12_+_20413445	2.335	NM_000921	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr1_+_159495140	2.334	NM_001102566	PCP4L1	Purkinje cell protein 4 like 1
chr10_-_134449467	2.333	NM_177400	NKX6-2	NK6 homeobox 2
chr4_+_156899575	2.333	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr15_-_50869379	2.312	NM_004498	ONECUT1	one cut homeobox 1
chr18_+_73090913	2.309	NM_001480	GALR1	galanin receptor 1
chr17_+_11085464	2.308	NM_001173461 NM_001173462 NM_207386	SHISA6	shisa homolog 6 (Xenopus laevis)
chr3_+_128830656	2.302	NM_015720	PODXL2	podocalyxin-like 2
chr21_+_37300732	2.301	NM_018962	DSCR6	Down syndrome critical region gene 6
chr18_-_23019176	2.297	NM_031422	CHST9	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr17_-_60986905	2.292		AXIN2	axin 2
chr9_-_95757448	2.287		BARX1	BARX homeobox 1
chr20_-_21326046	2.276	NM_033176	NKX2-4	NK2 homeobox 4
chr3_+_11009436	2.271		SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr22_-_31784328	2.270	NM_001135774	SYN3	synapsin III
chr2_-_106869488	2.266
chr7_-_156494741	2.266	NM_001165255	MNX1	motor neuron and pancreas homeobox 1
chr21_+_37300940	2.247
chr22_-_17517795	2.246	NM_005315	GSC2	goosecoid homeobox 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.78	2.68e-22	GO:0007399	nervous system development
1.88	5.11e-19	GO:0032502	developmental process
1.92	1.75e-18	GO:0007275	multicellular organismal development
2.03	1.88e-17	GO:0048731	system development
3.03	3.72e-16	GO:0022008	neurogenesis
3.10	5.38e-16	GO:0048699	generation of neurons
3.00	7.24e-16	GO:0048468	cell development
1.91	1.14e-15	GO:0048856	anatomical structure development
2.20	2.04e-15	GO:0030154	cell differentiation
2.14	2.13e-14	GO:0048869	cellular developmental process
2.41	2.45e-14	GO:0009653	anatomical structure morphogenesis
3.73	2.59e-14	GO:0007417	central nervous system development
3.23	4.78e-14	GO:0030182	neuron differentiation
1.57	9.20e-13	GO:0032501	multicellular organismal process
3.38	1.19e-12	GO:0048666	neuron development
3.53	3.91e-12	GO:0000904	cell morphogenesis involved in differentiation
3.87	9.64e-11	GO:0007420	brain development
3.59	1.71e-10	GO:0007409	axonogenesis
3.07	3.54e-10	GO:0000902	cell morphogenesis
3.91	5.67e-10	GO:0007411	axon guidance
3.47	6.15e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
3.29	6.65e-10	GO:0031175	neuron projection development
2.01	6.99e-10	GO:0048513	organ development
1.65	9.04e-10	GO:0023052	signaling
3.41	1.14e-09	GO:0048812	neuron projection morphogenesis
2.91	3.08e-09	GO:0032989	cellular component morphogenesis
1.39	4.24e-09	GO:0050794	regulation of cellular process
3.16	5.18e-09	GO:0048858	cell projection morphogenesis
3.13	7.06e-09	GO:0032990	cell part morphogenesis
2.04	1.41e-08	GO:0023051	regulation of signaling
1.34	1.41e-07	GO:0050789	regulation of biological process
2.96	3.88e-07	GO:0019226	transmission of nerve impulse
2.96	3.88e-07	GO:0035637	multicellular organismal signaling
1.31	4.85e-07	GO:0065007	biological regulation
2.66	5.49e-07	GO:0030030	cell projection organization
5.76	2.86e-06	GO:0045761	regulation of adenylate cyclase activity
5.65	4.05e-06	GO:0031279	regulation of cyclase activity
2.94	5.51e-06	GO:0007268	synaptic transmission
5.53	5.68e-06	GO:0051339	regulation of lyase activity
5.22	5.87e-06	GO:0030814	regulation of cAMP metabolic process
1.55	6.99e-06	GO:0007165	signal transduction
2.55	1.56e-05	GO:0009887	organ morphogenesis
2.69	1.61e-05	GO:0006935	chemotaxis
2.69	1.61e-05	GO:0042330	taxis
4.45	1.69e-05	GO:0019935	cyclic-nucleotide-mediated signaling
4.66	1.72e-05	GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
2.40	2.38e-05	GO:0009790	embryo development
2.09	2.51e-05	GO:0010646	regulation of cell communication
4.75	2.90e-05	GO:0030799	regulation of cyclic nucleotide metabolic process
4.99	3.16e-05	GO:0030817	regulation of cAMP biosynthetic process
1.79	3.34e-05	GO:0007166	cell surface receptor linked signaling pathway
4.10	3.55e-05	GO:0030900	forebrain development
2.21	4.01e-05	GO:0040011	locomotion
3.18	4.27e-05	GO:0007610	behavior
2.09	5.84e-05	GO:0007154	cell communication
8.45	6.57e-05	GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
8.45	6.57e-05	GO:0009187	cyclic nucleotide metabolic process
8.45	6.57e-05	GO:0010578	regulation of adenylate cyclase activity involved in G-protein signaling pathway
8.45	6.57e-05	GO:0010579	positive regulation of adenylate cyclase activity by G-protein signaling pathway
2.52	1.09e-04	GO:0007186	G-protein coupled receptor protein signaling pathway
4.61	1.10e-04	GO:0030802	regulation of cyclic nucleotide biosynthetic process
4.61	1.10e-04	GO:0030808	regulation of nucleotide biosynthetic process
4.84	1.23e-04	GO:0019933	cAMP-mediated signaling
1.67	1.28e-04	GO:0048523	negative regulation of cellular process
7.09	1.35e-04	GO:0007190	activation of adenylate cyclase activity
6.96	1.69e-04	GO:0031281	positive regulation of cyclase activity
6.96	1.69e-04	GO:0045762	positive regulation of adenylate cyclase activity
2.24	1.69e-04	GO:0007267	cell-cell signaling
5.02	1.77e-04	GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
1.63	1.90e-04	GO:0048519	negative regulation of biological process
6.71	2.62e-04	GO:0051349	positive regulation of lyase activity
4.60	6.16e-04	GO:0007611	learning or memory
2.88	6.34e-04	GO:0044057	regulation of system process
3.30	9.31e-04	GO:0002009	morphogenesis of an epithelium
2.06	1.21e-03	GO:0009888	tissue development
1.54	1.26e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54	1.26e-03	GO:0031326	regulation of cellular biosynthetic process
1.83	1.29e-03	GO:0051239	regulation of multicellular organismal process
1.53	1.30e-03	GO:0009889	regulation of biosynthetic process
2.71	1.48e-03	GO:0048598	embryonic morphogenesis
2.13	1.60e-03	GO:2000026	regulation of multicellular organismal development
2.54	1.70e-03	GO:0032583	regulation of gene-specific transcription
3.53	1.77e-03	GO:0035239	tube morphogenesis
1.52	2.00e-03	GO:0051171	regulation of nitrogen compound metabolic process
4.20	2.12e-03	GO:0050890	cognition
2.97	2.28e-03	GO:0051960	regulation of nervous system development
1.95	2.34e-03	GO:0032879	regulation of localization
2.88	2.55e-03	GO:0048729	tissue morphogenesis
1.98	2.90e-03	GO:0050793	regulation of developmental process
5.93	3.17e-03	GO:0007194	negative regulation of adenylate cyclase activity
5.93	3.17e-03	GO:0031280	negative regulation of cyclase activity
5.93	3.17e-03	GO:0051350	negative regulation of lyase activity
10.76	3.36e-03	GO:0046058	cAMP metabolic process
1.93	3.44e-03	GO:0009605	response to external stimulus
2.65	3.50e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
3.64	3.95e-03	GO:0006813	potassium ion transport
2.81	4.05e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.92	4.88e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.53	5.65e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
4.39	5.74e-03	GO:0007202	activation of phospholipase C activity
2.57	6.26e-03	GO:0060429	epithelium development
4.35	6.49e-03	GO:0010863	positive regulation of phospholipase C activity
3.66	7.11e-03	GO:0060562	epithelial tube morphogenesis
2.78	7.65e-03	GO:0019932	second-messenger-mediated signaling
2.63	8.97e-03	GO:0007389	pattern specification process
1.72	9.39e-03	GO:0009966	regulation of signal transduction
1.54	9.86e-03	GO:0042221	response to chemical stimulus
4.18	1.04e-02	GO:0010518	positive regulation of phospholipase activity
4.79	1.14e-02	GO:0021953	central nervous system neuron differentiation
11.53	1.18e-02	GO:0035412	regulation of catenin import into nucleus
2.68	1.43e-02	GO:0006140	regulation of nucleotide metabolic process
2.33	1.53e-02	GO:0048646	anatomical structure formation involved in morphogenesis
4.02	1.64e-02	GO:0050796	regulation of insulin secretion
2.17	1.64e-02	GO:0006812	cation transport
2.36	1.66e-02	GO:0023057	negative regulation of signaling
3.59	1.70e-02	GO:0031644	regulation of neurological system process
3.78	1.72e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.35	1.75e-02	GO:0010648	negative regulation of cell communication
10.85	1.77e-02	GO:0021772	olfactory bulb development
10.85	1.77e-02	GO:0021988	olfactory lobe development
3.99	1.82e-02	GO:0010517	regulation of phospholipase activity
2.28	1.85e-02	GO:0030001	metal ion transport
3.75	1.90e-02	GO:0022604	regulation of cell morphogenesis
3.72	2.09e-02	GO:0051969	regulation of transmission of nerve impulse
3.91	2.26e-02	GO:0060193	positive regulation of lipase activity
3.66	2.54e-02	GO:0030111	regulation of Wnt receptor signaling pathway
3.46	2.69e-02	GO:0045165	cell fate commitment
2.22	3.04e-02	GO:0048585	negative regulation of response to stimulus
2.56	3.05e-02	GO:0051093	negative regulation of developmental process
3.81	3.08e-02	GO:0090276	regulation of peptide hormone secretion
2.01	3.13e-02	GO:0009890	negative regulation of biosynthetic process
2.08	3.28e-02	GO:0045893	positive regulation of transcription, DNA-dependent
3.11	3.62e-02	GO:0051051	negative regulation of transport
3.74	3.77e-02	GO:0002791	regulation of peptide secretion
3.74	3.77e-02	GO:0090087	regulation of peptide transport
1.98	3.80e-02	GO:0051049	regulation of transport
2.02	3.85e-02	GO:0010628	positive regulation of gene expression
2.51	4.25e-02	GO:0015672	monovalent inorganic cation transport
2.01	4.31e-02	GO:0031327	negative regulation of cellular biosynthetic process
3.49	4.45e-02	GO:0016055	Wnt receptor signaling pathway
1.34	4.54e-02	GO:0051716	cellular response to stimulus
1.37	4.84e-02	GO:0080090	regulation of primary metabolic process
4.51	4.95e-02	GO:0009123	nucleoside monophosphate metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.54	6.83e-09	GO:0005886	plasma membrane
1.52	2.52e-08	GO:0071944	cell periphery
3.10	9.22e-08	GO:0045202	synapse
1.73	4.55e-07	GO:0044459	plasma membrane part
1.27	8.95e-06	GO:0016020	membrane
1.31	1.43e-05	GO:0044425	membrane part
1.85	8.63e-05	GO:0031226	intrinsic to plasma membrane
4.10	8.78e-05	GO:0034703	cation channel complex
1.86	8.87e-05	GO:0005887	integral to plasma membrane
2.64	9.25e-05	GO:0043005	neuron projection
1.32	1.66e-04	GO:0031224	intrinsic to membrane
4.95	1.71e-04	GO:0008076	voltage-gated potassium channel complex
4.95	1.71e-04	GO:0034705	potassium channel complex
2.79	5.95e-04	GO:0044456	synapse part
1.31	7.92e-04	GO:0016021	integral to membrane
3.10	1.01e-03	GO:0034702	ion channel complex
1.84	7.25e-03	GO:0042995	cell projection
2.95	1.51e-02	GO:0030424	axon
1.95	2.62e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.52	2.77e-07	GO:0043565	sequence-specific DNA binding
2.11	5.66e-06	GO:0001071	nucleic acid binding transcription factor activity
2.11	5.66e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
3.62	7.93e-05	GO:0005244	voltage-gated ion channel activity
3.62	7.93e-05	GO:0022832	voltage-gated channel activity
2.62	1.98e-04	GO:0022838	substrate-specific channel activity
1.94	2.94e-04	GO:0030528	transcription regulator activity
3.90	3.37e-04	GO:0022843	voltage-gated cation channel activity
2.54	3.94e-04	GO:0015267	channel activity
2.58	4.12e-04	GO:0005216	ion channel activity
2.54	4.16e-04	GO:0022803	passive transmembrane transporter activity
2.29	4.43e-04	GO:0008324	cation transmembrane transporter activity
2.91	7.49e-04	GO:0005261	cation channel activity
1.97	8.06e-04	GO:0022891	substrate-specific transmembrane transporter activity
2.04	1.23e-03	GO:0015075	ion transmembrane transporter activity
2.66	2.55e-03	GO:0022836	gated channel activity
11.53	2.73e-03	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity
8.97	3.11e-03	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
10.85	4.11e-03	GO:0030552	cAMP binding
8.61	4.20e-03	GO:0004112	cyclic-nucleotide phosphodiesterase activity
3.66	5.90e-03	GO:0005267	potassium channel activity
20.49	6.13e-03	GO:0008504	monoamine transmembrane transporter activity
1.83	6.97e-03	GO:0022857	transmembrane transporter activity
7.97	7.33e-03	GO:0016849	phosphorus-oxygen lyase activity
7.97	7.33e-03	GO:0030551	cyclic nucleotide binding
1.79	7.39e-03	GO:0022892	substrate-specific transporter activity
6.65	7.86e-03	GO:0008227	G-protein coupled amine receptor activity
7.68	9.50e-03	GO:0009975	cyclase activity
8.78	1.61e-02	GO:0017147	Wnt-protein binding
3.97	1.87e-02	GO:0015081	sodium ion transmembrane transporter activity
1.67	1.89e-02	GO:0005215	transporter activity
6.94	1.94e-02	GO:0008376	acetylgalactosaminyltransferase activity
4.59	2.26e-02	GO:0030165	PDZ domain binding
3.76	3.14e-02	GO:0005249	voltage-gated potassium channel activity
7.68	3.68e-02	GO:0016208	AMP binding