Motif ID: HNF1A.p2

Z-value: 1.197


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A



Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_24491498 2.546 NM_001195610
DCDC2
doublecortin domain containing 2
chr11_-_117200618 2.445 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr5_+_1278469 1.956 NM_182632
SLC6A18
solute carrier family 6, member 18
chr14_+_20226762 1.569 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr1_-_20014180 1.556 NM_019062
RNF186
ring finger protein 186
chr19_-_40995564 1.525 PRODH2
proline dehydrogenase (oxidase) 2
chr17_-_61655915 1.449 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_234333653 1.401 NM_000463
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
chr1_+_18680010 1.379 NM_152375
KLHDC7A
kelch domain containing 7A
chr5_+_73145098 1.313 RGNEF
190 kDa guanine nucleotide exchange factor
chr5_+_175908948 1.288 NM_017675
CDHR2
cadherin-related family member 2
chr16_-_86527608 1.284 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr1_-_204455269 1.257 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr19_-_40995606 1.233 PRODH2
proline dehydrogenase (oxidase) 2
chr6_-_29752909 1.228 NM_001109809
ZFP57
zinc finger protein 57 homolog (mouse)
chr10_+_85923473 1.167 NM_207373
C10orf99
chromosome 10 open reading frame 99
chrX_+_135079120 1.163 NM_001159704
FHL1
four and a half LIM domains 1
chr6_+_31815703 1.158 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6ORF26
MSH5



MSH5-C6orf26 read-through transcript
mutS homolog 5 (E. coli)



chr2_+_27573206 1.138 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr6_-_31007905 1.112 NM_205854
SFTA2
surfactant associated 2
chr7_+_45894480 1.098 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr1_+_17779528 1.095 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_-_87102453 1.083 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr1_+_42391678 1.053 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr20_+_42417752 1.039 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr8_-_18585721 1.018 PSD3
pleckstrin and Sec7 domain containing 3
chr8_-_124818754 1.005 NM_001003954
NM_004306
ANXA13

annexin A13

chr1_-_42402973 0.991 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr7_+_128802719 0.962 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr6_-_116488458 0.955 NM_002031
FRK
fyn-related kinase
chr13_-_32658215 0.954 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_-_186970366 0.950 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr16_+_79829794 0.937 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_-_88208650 0.918 NM_001443
FABP1
fatty acid binding protein 1, liver
chr7_-_104354325 0.914 LOC723809
hypothetical LOC723809
chr6_-_29120930 0.913 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr7_+_139175420 0.910 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr6_+_161043214 0.852 NM_000301
NM_001168338
PLG

plasminogen

chr16_-_54466709 0.826 NM_001143685
NM_145024
CES5A

carboxylesterase 5A

chr2_+_87828718 0.815 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr6_+_31081707 0.795 NM_001198815
PBMUCL1
panbronchiolitis related mucin-like 1
chr19_+_46201665 0.792 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr19_+_14913298 0.789 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr7_+_72913424 0.772 NM_182504
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr20_+_42417502 0.752 HNF4A
hepatocyte nuclear factor 4, alpha
chr2_-_1925880 0.741 MYT1L
myelin transcription factor 1-like
chr2_+_28572441 0.741 NM_001170585
NM_153021
PLB1

phospholipase B1

chr13_+_50813168 0.734 NM_001101320
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr6_+_31731647 0.707 NM_019101
APOM
apolipoprotein M
chr2_+_234191029 0.707 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_28892366 0.701 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr22_+_21027538 0.700


chr11_-_62539857 0.697 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr16_+_21152516 0.691 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chrX_+_107174855 0.683 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr7_+_104539548 0.676 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr17_+_69781980 0.655 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr6_+_31731667 0.653 APOM
apolipoprotein M
chr9_-_122852356 0.649 NM_001735
C5
complement component 5
chr16_-_20271530 0.647 NM_001008389
NM_003361
UMOD

uromodulin

chr21_-_35153664 0.624 RUNX1
runt-related transcription factor 1
chr17_+_38306339 0.617 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr3_+_63928459 0.594 NM_001128149
ATXN7
ataxin 7
chr14_-_93924663 0.589 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_-_108579270 0.585 NM_001146
ANGPT1
angiopoietin 1
chr3_-_33675484 0.572 CLASP2
cytoplasmic linker associated protein 2
chr14_+_38772870 0.569 NM_054024
MIA2
melanoma inhibitory activity 2
chr20_+_42463419 0.567 HNF4A
hepatocyte nuclear factor 4, alpha
chr2_-_170138558 0.558 NM_024622
FASTKD1
FAST kinase domains 1
chr9_+_81376666 0.557 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr10_+_99334411 0.549 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr16_-_46826588 0.545 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr6_+_155453114 0.522 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_+_167456230 0.521 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr1_+_160618143 0.495 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr1_-_202449659 0.494 NM_198447
GOLT1A
golgi transport 1A
chr17_+_1592879 0.489 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr10_-_32707549 0.465 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr17_+_32807040 0.462 NM_173625
C17orf78
chromosome 17 open reading frame 78
chr2_-_1905508 0.460 MYT1L
myelin transcription factor 1-like
chr20_+_42463387 0.454 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_+_11211282 0.448 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr2_+_151922350 0.438 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_+_29249289 0.424 NM_030905
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr17_-_10393664 0.421 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr10_-_101680645 0.416 DNMBP
dynamin binding protein
chr14_-_93924873 0.409 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr3_+_188397967 0.403 NM_153708
RTP1
receptor (chemosensory) transporter protein 1
chr12_-_122400937 0.394 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr4_+_56731117 0.387 NM_020722
KIAA1211
KIAA1211
chr20_+_42463350 0.386 HNF4A
hepatocyte nuclear factor 4, alpha
chr15_-_49184764 0.383 NM_207381
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr4_-_72868598 0.379 NM_000583
GC
group-specific component (vitamin D binding protein)
chr3_+_187866464 0.365 NM_000412
HRG
histidine-rich glycoprotein
chr2_+_101981888 0.365 NM_173343
IL1R2
interleukin 1 receptor, type II
chr7_-_27186400 0.364 NM_153715
HOXA10
homeobox A10
chr1_+_109057078 0.361 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr6_+_158990982 0.357 NM_001009991
SYTL3
synaptotagmin-like 3
chr7_-_27133163 0.346 NM_153631
HOXA3
homeobox A3
chr15_+_60726801 0.344 NM_015059
TLN2
talin 2
chr4_-_102487649 0.342 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr6_+_121798443 0.342 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr3_-_168674502 0.341 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr7_-_87694218 0.338 NM_198901
SRI
sorcin
chr3_-_171070314 0.332 NM_024727
LRRC31
leucine rich repeat containing 31
chr10_+_69539255 0.330 NM_032578
MYPN
myopalladin
chr11_+_64114857 0.329 NM_144585
NM_153378
SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

chr7_-_107667728 0.328 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr17_+_71154240 0.326 NM_001162997
LOC100130933
hypothetical protein LOC100130933
chr1_-_246071820 0.325 NM_001001959
OR11L1
olfactory receptor, family 11, subfamily L, member 1
chr3_-_25654659 0.323 TOP2B
topoisomerase (DNA) II beta 180kDa
chr17_+_1592893 0.320 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr6_+_155579788 0.308 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_+_147775652 0.303 FBXO38
F-box protein 38
chr6_+_64289585 0.302 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chrX_+_70351773 0.298 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chr5_+_156540425 0.295 NM_005546
ITK
IL2-inducible T-cell kinase
chrX_+_70351812 0.295 GJB1
gap junction protein, beta 1, 32kDa
chr5_+_67622242 0.294 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr2_+_234266250 0.292 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr21_-_42219849 0.292 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr2_+_62787534 0.290 NM_001142614
EHBP1
EH domain binding protein 1
chr20_+_42463279 0.290 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr19_-_38052481 0.289 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr2_-_99284070 0.281 NM_174898
LYG1
lysozyme G-like 1
chr14_-_93859394 0.280 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr7_-_107930170 0.278 PNPLA8
patatin-like phospholipase domain containing 8
chr14_+_95915774 0.270 NM_016472
C14orf129
chromosome 14 open reading frame 129
chr14_+_64240996 0.270 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_+_76549658 0.270 RPTOR
regulatory associated protein of MTOR, complex 1
chr17_-_24253821 0.258 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr6_-_26038817 0.257 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr4_-_69852090 0.256 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr20_+_61841553 0.251 NM_020062
SLC2A4RG
SLC2A4 regulator
chr2_+_234302511 0.249 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr15_-_96875133 0.248 NM_182562
FAM169B
family with sequence similarity 169, member B
chr1_-_114231691 0.246 NM_001010922
BCL2L15
BCL2-like 15
chr5_-_138746840 0.245 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr6_-_29563657 0.241 NM_052967
MAS1L
MAS1 oncogene-like
chr8_-_17797127 0.238 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr14_+_19473606 0.236 NM_001004063
OR4K1
olfactory receptor, family 4, subfamily K, member 1
chr2_+_101874809 0.233 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_-_107230867 0.232 NM_000111
SLC26A3
solute carrier family 26, member 3
chr10_+_99334069 0.231 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr12_+_91620749 0.230 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_-_157950898 0.228 NM_000567
CRP
C-reactive protein, pentraxin-related
chr11_-_101292462 0.226 NM_178127
ANGPTL5
angiopoietin-like 5
chr1_-_67039518 0.225 NM_005478
INSL5
insulin-like 5
chr1_+_184532027 0.225 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr7_-_50600536 0.224 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr20_+_35406497 0.221 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr4_-_74704964 0.219 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr12_-_54965996 0.219 CS
citrate synthase
chr19_-_11500912 0.217 NM_001142464
NM_001142465
NM_016581
ECSIT


ECSIT homolog (Drosophila)


chr4_+_187424111 0.217 NM_000128
F11
coagulation factor XI
chr17_-_53335748 0.216 NM_017949
CUEDC1
CUE domain containing 1
chr3_-_158704056 0.215 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr2_-_63518589 0.214 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr1_-_228916559 0.214 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr19_-_40996040 0.213 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr10_+_35466715 0.213 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr1_+_55044323 0.210 NM_001110533
NM_152607
C1orf177

chromosome 1 open reading frame 177

chr17_+_1593040 0.207 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_+_93830169 0.205 LOC100129046
hypothetical LOC100129046
chr10_+_18669619 0.205 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_108252200 0.204 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr12_-_122322117 0.203 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr16_-_67943157 0.201 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chr10_-_85921703 0.196 LOC642934
hypothetical LOC642934
chr2_+_182558795 0.194 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr10_+_101532450 0.194 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_+_98772537 0.193 MTDH
metadherin
chr1_+_93830106 0.191 LOC100129046
hypothetical LOC100129046
chr12_+_10222823 0.190 NM_153022
C12orf59
chromosome 12 open reading frame 59
chr11_-_67207112 0.189 RPL37
ribosomal protein L37
chr6_-_33862690 0.184 NM_001143944
LEMD2
LEM domain containing 2
chr4_+_154345039 0.183 NM_015271
TRIM2
tripartite motif containing 2
chr4_-_189263395 0.182 NM_173553
TRIML2
tripartite motif family-like 2
chr10_-_69736600 0.181 PBLD
phenazine biosynthesis-like protein domain containing
chr17_-_19290745 0.179


chr5_-_39430180 0.178 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr22_-_30981317 0.174 NM_014227
SLC5A4
solute carrier family 5 (low affinity glucose cotransporter), member 4
chr13_-_98757634 0.169 NM_004951
GPR183
G protein-coupled receptor 183
chr11_-_8695974 0.168 ST5
suppression of tumorigenicity 5
chr7_-_36992221 0.167 NM_130442
ELMO1
engulfment and cell motility 1
chr7_-_44547382 0.165 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr16_+_88224276 0.163 DPEP1
dipeptidase 1 (renal)
chr13_-_99983945 0.161 NM_033110
A2LD1
AIG2-like domain 1
chr15_+_83724743 0.160 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr1_-_195818927 0.159 DENND1B
DENN/MADD domain containing 1B
chr18_+_21967813 0.158 NM_001025096
NM_001025097
NM_144662
PSMA8


proteasome (prosome, macropain) subunit, alpha type, 8


chr7_+_113853790 0.158 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr1_-_9052253 0.158 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr4_+_187227302 0.157 NM_003265
TLR3
toll-like receptor 3
chr2_-_160181206 0.156 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr15_+_22772545 0.154 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr11_-_123130435 0.149 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr2_+_101874765 0.148 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_57209319 0.148 NM_003865
HESX1
HESX homeobox 1
chr4_+_148872661 0.147 ARHGAP10
Rho GTPase activating protein 10

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.