Motif ID: MAFB.p2

Z-value: 2.204


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)



Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_113726203 3.634 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_+_104838177 3.519 NM_006236
POU3F3
POU class 3 homeobox 3
chr22_+_28206180 3.306 NM_021076
NEFH
neurofilament, heavy polypeptide
chr1_+_63561317 2.981 NM_012183
FOXD3
forkhead box D3
chr8_+_85258007 2.394 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chrX_+_68641802 2.337 NM_015686
FAM155B
family with sequence similarity 155, member B
chr14_+_28305922 2.199 NM_005249
FOXG1
forkhead box G1
chr8_+_65656164 2.035 BHLHE22
basic helix-loop-helix family, member e22
chr10_+_124885556 1.985 NM_001105574
HMX3
H6 family homeobox 3
chr2_+_176680251 1.964 NM_021192
HOXD11
homeobox D11
chr6_+_72653126 1.944 RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_113725914 1.918 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chrX_+_72140076 1.893 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr17_-_47590669 1.893 CA10
carbonic anhydrase X
chr2_+_74595073 1.892 NM_016170
TLX2
T-cell leukemia homeobox 2
chr13_-_78075683 1.835 NM_006237
POU4F1
POU class 4 homeobox 1
chr17_+_56831951 1.710 NM_005994
TBX2
T-box 2
chr8_+_31616809 1.668 NM_013962
NRG1
neuregulin 1
chr16_+_1979959 1.648 NM_004209
SYNGR3
synaptogyrin 3
chr16_-_47873183 1.607 NM_004352
CBLN1
cerebellin 1 precursor
chr17_+_56832255 1.563 TBX2
T-box 2
chr18_+_53253775 1.561 NM_004852
ONECUT2
one cut homeobox 2
chr14_+_28306633 1.522 FOXG1
forkhead box G1
chr19_-_13478037 1.507 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr4_-_111763655 1.470 NM_000325
PITX2
paired-like homeodomain 2
chr1_+_63561632 1.409 FOXD3
forkhead box D3
chr15_-_50869379 1.409 NM_004498
ONECUT1
one cut homeobox 1
chr17_-_71747867 1.383 NM_052916
RNF157
ring finger protein 157
chr6_+_72653369 1.376 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_6162669 1.370 NM_015557
CHD5
chromodomain helicase DNA binding protein 5
chr10_-_132999798 1.367 TCERG1L
transcription elongation regulator 1-like
chr14_-_59407103 1.363 NM_021136
RTN1
reticulon 1
chr3_-_62835601 1.341


chr11_-_32413635 1.340 NM_000378
NM_024424
NM_024426
WT1


Wilms tumor 1


chr10_-_99780574 1.338 NM_018058
CRTAC1
cartilage acidic protein 1
chr10_-_99780336 1.318 CRTAC1
cartilage acidic protein 1
chr2_-_192767494 1.303 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr15_-_81037554 1.302 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr4_+_61749540 1.286 LPHN3
latrophilin 3
chr3_+_148610516 1.277 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr14_+_73775927 1.247 NM_182894
VSX2
visual system homeobox 2
chr4_-_105631915 1.242 NM_025212
CXXC4
CXXC finger protein 4
chr18_-_24010944 1.235 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_111763356 1.234 PITX2
paired-like homeodomain 2
chr9_-_34579679 1.231 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr17_-_44058612 1.217 NM_024017
HOXB9
homeobox B9
chr12_+_93066370 1.211 NM_005761
PLXNC1
plexin C1
chrX_-_72215949 1.206 NM_001012977
PABPC1L2A
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2A
poly(A) binding protein, cytoplasmic 1-like 2B
chr9_+_966963 1.185 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr22_+_24895454 1.182 SEZ6L
seizure related 6 homolog (mouse)-like
chr8_+_85258056 1.173 NM_173848
RALYL
RALY RNA binding protein-like
chr2_-_42573980 1.168 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr6_+_19946591 1.160


chr1_-_99242765 1.158 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr5_-_44424423 1.157 NM_004465
FGF10
fibroblast growth factor 10
chr10_+_83625049 1.155 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr3_+_71885890 1.142 NM_018971
GPR27
G protein-coupled receptor 27
chr7_+_7188667 1.141 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr3_-_88190737 1.122 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chrX_-_107866262 1.113 NM_003604
IRS4
insulin receptor substrate 4
chrX_-_74062005 1.110 NM_001008537
KIAA2022
KIAA2022
chr2_-_47650973 1.091 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr10_-_73518315 1.081 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_175400573 1.081 NM_004319
NM_207108
ASTN1

astrotactin 1

chr6_+_124166767 1.074 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr8_+_56177567 1.060 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr13_+_27264779 1.059 NM_145657
GSX1
GS homeobox 1
chr5_-_146238336 1.053 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr15_+_31390454 1.040 NM_001036
RYR3
ryanodine receptor 3
chr16_+_25610847 1.038 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr20_-_31495086 1.032 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr17_+_56832492 1.032 TBX2
T-box 2
chr11_-_129803515 1.026 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr8_+_24827181 1.024 NEFM
neurofilament, medium polypeptide
chr2_+_185171537 1.024 ZNF804A
zinc finger protein 804A
chr1_-_102235377 1.017 NM_058170
OLFM3
olfactomedin 3
chr2_-_219566364 1.007 NM_005209
NM_057093
NM_057094
CRYBA2


crystallin, beta A2


chr4_-_168392266 1.001 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_-_98699628 0.992 NM_139057
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr4_+_158361185 0.980 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr10_-_132999973 0.979 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr14_+_37748031 0.978 SSTR1
somatostatin receptor 1
chr6_+_99389318 0.971 POU3F2
POU class 3 homeobox 2
chr9_+_99656013 0.971


chr5_+_75734759 0.963 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_-_79855618 0.955 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr4_-_41848874 0.950 BEND4
BEN domain containing 4
chr4_-_74343320 0.947 NM_032217
NM_198889
ANKRD17

ankyrin repeat domain 17

chr12_-_79855580 0.945 LIN7A
lin-7 homolog A (C. elegans)
chr5_+_140780797 0.935 PCDHGA11
protocadherin gamma subfamily A, 11
chr11_-_129803712 0.930 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chrX_-_30237403 0.924 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr2_-_236741352 0.921 NM_001485
GBX2
gastrulation brain homeobox 2
chr3_+_85090721 0.921 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr4_+_147779492 0.920 NM_004575
POU4F2
POU class 4 homeobox 2
chr3_-_71886203 0.920 NM_001134649
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr8_+_24827173 0.917 NM_005382
NEFM
neurofilament, medium polypeptide
chr13_+_27610379 0.916 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_-_102234959 0.907 OLFM3
olfactomedin 3
chr1_+_175407153 0.904 NM_021165
FAM5B
family with sequence similarity 5, member B
chr14_+_37748345 0.901 SSTR1
somatostatin receptor 1
chr1_-_38285033 0.898 NM_002699
POU3F1
POU class 3 homeobox 1
chr18_-_30056431 0.895 NM_001198547
NOL4
nucleolar protein 4
chr7_-_27206249 0.894 NM_000522
HOXA13
homeobox A13
chr8_-_121893468 0.893 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chrX_+_136476353 0.891 ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr19_+_11510578 0.884 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr5_-_147142457 0.877 JAKMIP2
janus kinase and microtubule interacting protein 2
chr2_+_185171682 0.872 ZNF804A
zinc finger protein 804A
chr4_-_174686918 0.872 HAND2
heart and neural crest derivatives expressed 2
chr13_-_27441143 0.871 CDX2
caudal type homeobox 2
chr5_+_170779664 0.866 FGF18
fibroblast growth factor 18
chr15_-_81113676 0.864 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr13_-_71338558 0.863 DACH1
dachshund homolog 1 (Drosophila)
chr3_-_124650081 0.861 NM_183357
ADCY5
adenylate cyclase 5
chr10_+_25504295 0.857 NM_020752
GPR158
G protein-coupled receptor 158
chr5_-_147142444 0.854 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr18_+_74841262 0.848 NM_171999
SALL3
sal-like 3 (Drosophila)
chrX_+_21302317 0.848 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr13_+_34414390 0.845 NM_015678
NBEA
neurobeachin
chr2_-_206659140 0.839 NM_017759
INO80D
INO80 complex subunit D
chr6_+_110406890 0.837 NM_005284
GPR6
G protein-coupled receptor 6
chr11_+_65945050 0.828 NM_178864
NPAS4
neuronal PAS domain protein 4
chr11_-_75599433 0.826 WNT11
wingless-type MMTV integration site family, member 11
chr4_+_3738093 0.822 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr4_-_174687104 0.821 HAND2
heart and neural crest derivatives expressed 2
chr11_+_17714070 0.820 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr5_+_140780720 0.819 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chr20_+_52525538 0.816 NM_018431
DOK5
docking protein 5
chr2_-_219881937 0.813 PTPRN
protein tyrosine phosphatase, receptor type, N
chr7_-_103417198 0.812 NM_005045
NM_173054
RELN

reelin

chr2_-_227371698 0.808 NM_005544
IRS1
insulin receptor substrate 1
chr15_-_32875040 0.805 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr17_+_14145051 0.801 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr8_+_1937711 0.800 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr13_-_50315832 0.791 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr1_-_175400665 0.791 ASTN1
astrotactin 1
chr5_-_63293301 0.790 NM_000524
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr4_-_85638410 0.789 NM_006168
NKX6-1
NK6 homeobox 1
chr14_-_62581656 0.784 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr17_+_56884560 0.780 TBX4
T-box 4
chr9_+_967386 0.780 DMRT3
doublesex and mab-3 related transcription factor 3
chr11_+_108798084 0.779 C11orf87
chromosome 11 open reading frame 87
chr10_-_73518284 0.777 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr11_-_132318741 0.775 OPCML
opioid binding protein/cell adhesion molecule-like
chrX_+_147389825 0.774 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr6_+_72653420 0.772 RIMS1
regulating synaptic membrane exocytosis 1
chr10_-_73518269 0.772 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_111018798 0.770 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr3_-_10724715 0.768 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr4_-_17632456 0.768 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr3_+_49566901 0.767 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr2_+_198377561 0.765 NM_006226
PLCL1
phospholipase C-like 1
chrX_+_23262905 0.762 NM_173495
PTCHD1
patched domain containing 1
chr9_-_37024358 0.757 NM_016734
PAX5
paired box 5
chr4_-_44145266 0.754 KCTD8
potassium channel tetramerisation domain containing 8
chrX_-_1470862 0.753 NM_001636
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr8_-_132122016 0.752 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr20_+_20296744 0.752 NM_002196
INSM1
insulinoma-associated 1
chrX_+_151557292 0.744 NM_018558
GABRQ
gamma-aminobutyric acid (GABA) receptor, theta
chr8_+_85258257 0.744 RALYL
RALY RNA binding protein-like
chr5_-_147142368 0.739 JAKMIP2
janus kinase and microtubule interacting protein 2
chr5_-_59225377 0.736 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_+_550394 0.735 NM_145270
C16orf11
chromosome 16 open reading frame 11
chr4_-_44145580 0.734 NM_198353
KCTD8
potassium channel tetramerisation domain containing 8
chr6_+_1257674 0.733 NM_033260
FOXQ1
forkhead box Q1
chr3_+_195889845 0.733 FAM43A
family with sequence similarity 43, member A
chr1_+_154878344 0.729 NM_021948
NM_198427
BCAN

brevican

chr17_-_25642962 0.727 NM_000386
BLMH
bleomycin hydrolase
chr14_-_26136799 0.727 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr9_-_84867862 0.725 NM_152573
RASEF
RAS and EF-hand domain containing
chr3_+_54131731 0.720 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr4_-_5945596 0.717 NM_001014809
CRMP1
collapsin response mediator protein 1
chr11_+_22171150 0.715 NM_001142649
NM_213599
ANO5

anoctamin 5

chr22_+_24895623 0.712 SEZ6L
seizure related 6 homolog (mouse)-like
chr22_+_24895424 0.709 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr14_+_101097440 0.708 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr3_-_62836052 0.706 NM_003716
NM_183393
NM_183394
CADPS


Ca++-dependent secretion activator


chr16_+_65840275 0.704 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr8_-_57521702 0.704 NM_001135690
PENK
proenkephalin
chr19_-_16599986 0.701 NM_004831
MED26
mediator complex subunit 26
chr11_+_56984702 0.698 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr8_+_1936549 0.696 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr12_-_78852815 0.692 PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr3_+_3816079 0.687 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr7_-_20791907 0.678


chr1_-_239587007 0.677 RGS7
regulator of G-protein signaling 7
chr5_+_31229609 0.672 CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr3_+_182912769 0.671 SOX2
SRY (sex determining region Y)-box 2
chr5_-_147142249 0.668 JAKMIP2
janus kinase and microtubule interacting protein 2
chr17_+_25467948 0.667 NM_032141
CCDC55
coiled-coil domain containing 55
chr2_-_219558517 0.666 NM_017521
FEV
FEV (ETS oncogene family)
chr1_-_175400441 0.665 ASTN1
astrotactin 1
chr1_-_111019051 0.663


chr11_+_108798047 0.662 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr9_-_16717887 0.661 BNC2
basonuclin 2
chr15_+_90738108 0.661 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr2_+_176665694 0.660 NM_000523
HOXD13
homeobox D13
chr10_+_95316387 0.659 NM_001195755
NM_181745
GPR120

G protein-coupled receptor 120

chr11_-_32408934 0.655 NM_001198551
NM_001198552
WT1

Wilms tumor 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.63 4.30e-08 GO:0007399 nervous system development
3.25 4.91e-08 GO:0048731 system development
2.85 2.90e-07 GO:0007275 multicellular organismal development
2.92 7.84e-07 GO:0048856 anatomical structure development
3.64 7.96e-07 GO:0030154 cell differentiation
3.54 1.43e-06 GO:0048869 cellular developmental process
2.59 3.56e-06 GO:0032502 developmental process
3.47 2.77e-05 GO:0048513 organ development
3.78 7.79e-05 GO:0009653 anatomical structure morphogenesis
4.83 2.72e-04 GO:0048699 generation of neurons
13.13 3.89e-04 GO:0045165 cell fate commitment
4.55 5.49e-04 GO:0022008 neurogenesis
25.59 5.87e-04 GO:0050808 synapse organization
15.66 8.90e-04 GO:0001822 kidney development
15.07 1.12e-03 GO:0072001 renal system development
6.17 1.61e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
4.47 1.74e-03 GO:0009888 tissue development
5.41 1.76e-03 GO:0009887 organ morphogenesis
33.27 2.50e-03 GO:0007416 synapse assembly
5.21 2.52e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.92 3.72e-03 GO:0032501 multicellular organismal process
4.86 4.90e-03 GO:0051254 positive regulation of RNA metabolic process
4.81 5.38e-03 GO:0010628 positive regulation of gene expression
11.42 5.57e-03 GO:0001655 urogenital system development
26.62 6.22e-03 GO:0001656 metanephros development
11.02 6.80e-03 GO:0043062 extracellular structure organization
4.68 7.06e-03 GO:0030182 neuron differentiation
6.75 8.78e-03 GO:0007389 pattern specification process
5.69 9.94e-03 GO:0048646 anatomical structure formation involved in morphogenesis
6.39 1.31e-02 GO:0007420 brain development
4.36 1.34e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
4.29 1.57e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.16 2.07e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
8.83 2.37e-02 GO:0048732 gland development
3.64 3.30e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
4.35 3.32e-02 GO:0045595 regulation of cell differentiation
133.02 3.62e-02 GO:0045110 intermediate filament bundle assembly
3.88 3.88e-02 GO:0031328 positive regulation of cellular biosynthetic process
6.35 4.45e-02 GO:0060284 regulation of cell development
10.57 4.48e-02 GO:0042692 muscle cell differentiation
3.82 4.52e-02 GO:0009891 positive regulation of biosynthetic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.83 3.69e-02 GO:0045202 synapse

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.76 2.78e-06 GO:0030528 transcription regulator activity
5.76 5.57e-06 GO:0043565 sequence-specific DNA binding
4.57 1.36e-05 GO:0001071 nucleic acid binding transcription factor activity
4.57 1.36e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
6.88 1.37e-03 GO:0016563 transcription activator activity
133.02 6.48e-03 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity
11.46 3.07e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity