Motif ID: MTF1.p2

Z-value: 3.273


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1



Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_121893468 6.163 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr15_-_27650218 5.519 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr14_+_101097440 5.092 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr8_-_121893449 4.817 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr5_-_11957127 4.781 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr9_+_90339835 4.669 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr8_+_56177567 4.544 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr18_+_74841262 4.410 NM_171999
SALL3
sal-like 3 (Drosophila)
chr10_-_103525646 4.167 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr5_-_11956964 4.036 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr19_+_1704661 4.031 NM_001080488
ONECUT3
one cut homeobox 3
chr8_-_121892877 3.791 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr8_-_121893196 3.789


chr8_-_140784416 3.752 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr11_-_2863536 3.607 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr9_+_139892049 3.567 NM_000718
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr10_+_83625049 3.529 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr16_-_87535106 3.501 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr2_+_74595073 3.461 NM_016170
TLX2
T-cell leukemia homeobox 2
chr16_-_51138306 3.398 NM_001080430
TOX3
TOX high mobility group box family member 3
chr9_-_93751900 3.259 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr16_+_1143738 3.203 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chrX_+_68641802 3.176 NM_015686
FAM155B
family with sequence similarity 155, member B
chr16_+_55180767 3.061 NM_005954
MT3
metallothionein 3
chr3_-_62835601 3.047


chr2_+_238060602 2.998 NM_001042467
NM_024101
MLPH

melanophilin

chr11_+_125279481 2.957 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr13_+_111769913 2.940 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr8_+_121892719 2.808


chr19_-_14177980 2.806 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr9_-_95757365 2.721 NM_021570
BARX1
BARX homeobox 1
chr2_+_120820140 2.697 NM_002193
INHBB
inhibin, beta B
chr10_-_28074752 2.689 NM_173576
MKX
mohawk homeobox
chr10_-_131652364 2.686 EBF3
early B-cell factor 3
chr7_+_86111887 2.669 GRM3
glutamate receptor, metabotropic 3
chr10_-_44200458 2.648 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr1_-_92721633 2.648 GFI1
growth factor independent 1 transcription repressor
chr2_-_233501069 2.627 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr7_-_35260213 2.609 NM_001077653
NM_001166220
TBX20

T-box 20

chr9_+_125813849 2.607 LHX2
LIM homeobox 2
chr9_-_95757448 2.584 BARX1
BARX homeobox 1
chr10_-_135088065 2.546 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr12_+_2032649 2.514 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr7_+_86111803 2.509 GRM3
glutamate receptor, metabotropic 3
chr7_+_86112012 2.492 GRM3
glutamate receptor, metabotropic 3
chr11_-_2248757 2.480 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr16_+_82559600 2.475 NM_019065
NECAB2
N-terminal EF-hand calcium binding protein 2
chr13_-_50315832 2.450 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr10_+_133850325 2.409 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr15_+_77511912 2.403 NM_015206
KIAA1024
KIAA1024
chr14_+_105012106 2.397 NM_001312
CRIP2
cysteine-rich protein 2
chr4_-_46690197 2.361 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr7_-_158630223 2.358 NM_003382
VIPR2
vasoactive intestinal peptide receptor 2
chr19_+_1397268 2.298 APC2
adenomatosis polyposis coli 2
chr14_+_73775927 2.289 NM_182894
VSX2
visual system homeobox 2
chr2_-_278181 2.267 NM_001002919
FAM150B
family with sequence similarity 150, member B
chr20_+_20296744 2.251 NM_002196
INSM1
insulinoma-associated 1
chr22_-_45311730 2.249 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr14_+_99181232 2.229 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr5_+_170668892 2.213 NM_021025
TLX3
T-cell leukemia homeobox 3
chr1_-_50661716 2.211 NM_032110
DMRTA2
DMRT-like family A2
chr2_-_230287442 2.151 NM_139072
DNER
delta/notch-like EGF repeat containing
chr11_+_627268 2.132 NM_000797
DRD4
dopamine receptor D4
chr20_-_538909 2.126 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr19_-_19233370 2.093 HAPLN4
hyaluronan and proteoglycan link protein 4
chr9_+_94987032 2.080 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr22_+_24895623 2.066 SEZ6L
seizure related 6 homolog (mouse)-like
chr3_-_48607596 2.044 NM_000094
COL7A1
collagen, type VII, alpha 1
chr10_+_69990050 2.029 NM_030625
TET1
tet oncogene 1
chr11_-_64268841 2.017 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_-_1525309 1.997 LOC643988
hypothetical LOC643988
chr22_+_42138034 1.992 MPPED1
metallophosphoesterase domain containing 1
chr4_+_3737872 1.986 ADRA2C
adrenergic, alpha-2C-, receptor
chr2_+_202607554 1.985 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr11_+_110675175 1.985 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr3_-_10724715 1.983 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr18_-_4445247 1.972 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr5_+_133478252 1.957 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr10_-_128884411 1.956 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr12_+_130878870 1.954 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr1_+_177979037 1.953 FAM163A
family with sequence similarity 163, member A
chr2_+_231610438 1.943 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr6_+_69401660 1.912 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr15_+_90738108 1.889 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_-_13158391 1.884 LOC285548
hypothetical LOC285548
chr22_+_42137955 1.883 NM_001044370
MPPED1
metallophosphoesterase domain containing 1
chr4_+_3738093 1.874 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr11_-_64269501 1.871 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr12_-_56418295 1.870 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr12_+_111980044 1.870 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr22_-_28041474 1.866 RASL10A
RAS-like, family 10, member A
chr16_+_54782802 1.821 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr3_+_71885890 1.807 NM_018971
GPR27
G protein-coupled receptor 27
chr2_+_100087812 1.797


chr19_+_38377329 1.795 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr2_-_204108151 1.792 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr1_-_925332 1.786 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr1_-_26245031 1.763 NM_001004434
NM_032513
SLC30A2

solute carrier family 30 (zinc transporter), member 2

chr11_+_359723 1.745 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr22_+_24895454 1.742 SEZ6L
seizure related 6 homolog (mouse)-like
chr8_+_26427378 1.737 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr1_+_52871603 1.718 NM_001042693
FAM159A
family with sequence similarity 159, member A
chr22_-_43783449 1.702 PHF21B
PHD finger protein 21B
chr22_+_24895424 1.695 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr17_-_29930431 1.686 NM_207454
C17orf102
chromosome 17 open reading frame 102
chrX_-_71442488 1.681 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr11_+_17697685 1.681 NM_002478
MYOD1
myogenic differentiation 1
chr4_+_4912272 1.675 NM_002448
MSX1
msh homeobox 1
chrX_+_152561086 1.675 NM_001395
DUSP9
dual specificity phosphatase 9
chr16_-_695719 1.671 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr3_+_3816079 1.670 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr6_+_137285071 1.669 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr11_+_14621972 1.665 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr12_+_5411534 1.656 NM_001102654
NTF3
neurotrophin 3
chr10_+_94439658 1.645 NM_002729
HHEX
hematopoietically expressed homeobox
chrX_-_132376660 1.641 NM_001448
GPC4
glypican 4
chr1_-_23623713 1.625 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr3_-_69064364 1.622 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr22_+_49386044 1.622 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr1_+_235272324 1.612 NM_001035
RYR2
ryanodine receptor 2 (cardiac)
chr17_-_34015631 1.607 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr14_-_99695684 1.599 NM_206918
DEGS2
degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)
chr2_-_128792515 1.592 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr14_+_95412481 1.589


chr12_+_48641545 1.579 NM_001651
AQP5
aquaporin 5
chr1_+_2975590 1.577 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr13_+_48692472 1.576 NM_001507
MLNR
motilin receptor
chr15_+_78483624 1.572 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_+_3307445 1.562 NM_152744
SDK1
sidekick homolog 1, cell adhesion molecule (chicken)
chr5_+_38294289 1.562 NM_152403
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr22_-_43784093 1.560 NM_138415
PHF21B
PHD finger protein 21B
chr11_-_69343128 1.559 NM_005247
FGF3
fibroblast growth factor 3
chr1_+_226937732 1.557 RHOU
ras homolog gene family, member U
chr10_+_134751398 1.552 NM_001083909
GPR123
G protein-coupled receptor 123
chr21_+_42946719 1.548 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr20_-_22514092 1.544 NM_153675
FOXA2
forkhead box A2
chr17_-_5344898 1.540 NM_001162371
LOC728392
hypothetical protein LOC728392
chr9_+_78824390 1.537 NM_001013735
FOXB2
forkhead box B2
chr12_+_131705438 1.531 NM_012226
NM_016318
NM_170682
NM_170683
NM_174872
NM_174873
P2RX2





purinergic receptor P2X, ligand-gated ion channel, 2





chr4_+_2031036 1.525 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr4_+_36923084 1.520 NM_001144990
KIAA1239
KIAA1239
chr10_+_50488352 1.514 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr10_+_23521464 1.506 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr22_+_47263919 1.505 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr16_+_25610847 1.498 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr16_+_1143241 1.497 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr20_-_60484420 1.489 NM_080473
GATA5
GATA binding protein 5
chr1_-_38285033 1.485 NM_002699
POU3F1
POU class 3 homeobox 1
chr2_+_5750229 1.482 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr1_-_925215 1.481 HES4
hairy and enhancer of split 4 (Drosophila)
chr16_+_65754788 1.470 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr6_-_165996031 1.468 LOC100132188
LP7097
chr1_-_239587007 1.455 RGS7
regulator of G-protein signaling 7
chr2_+_936534 1.453 NM_018968
SNTG2
syntrophin, gamma 2
chr22_+_28446288 1.446 NM_182527
CABP7
calcium binding protein 7
chr6_+_159510416 1.439 NM_032532
FNDC1
fibronectin type III domain containing 1
chr17_+_11085464 1.436 NM_001173461
NM_001173462
NM_207386
SHISA6


shisa homolog 6 (Xenopus laevis)


chr9_+_70509925 1.434 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr19_-_16998449 1.431 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr16_-_2186465 1.430 NM_020764
CASKIN1
CASK interacting protein 1
chr13_+_32488477 1.424 NM_004795
KL
klotho
chr10_-_88116181 1.423 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chrX_-_138114100 1.422 FGF13
fibroblast growth factor 13
chr17_-_47590975 1.421 CA10
carbonic anhydrase X
chr18_-_4445265 1.420 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr8_-_26427304 1.418 NM_007257
PNMA2
paraneoplastic antigen MA2
chr22_+_27931685 1.409 NM_133455
EMID1
EMI domain containing 1
chr2_-_106869488 1.407


chr5_+_149526533 1.400 NM_001804
CDX1
caudal type homeobox 1
chr16_-_49742651 1.393 NM_002968
SALL1
sal-like 1 (Drosophila)
chr16_+_88169612 1.389 NM_014427
NM_153636
CPNE7

copine VII

chr19_-_18198234 1.387 NM_001098818
PDE4C
phosphodiesterase 4C, cAMP-specific
chr17_-_47591123 1.387 NM_020178
CA10
carbonic anhydrase X
chr8_+_136538739 1.376 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr1_-_57661373 1.366 DAB1
disabled homolog 1 (Drosophila)
chr16_-_30288988 1.365 NM_015527
TBC1D10B
TBC1 domain family, member 10B
chr8_-_133562185 1.362 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr3_+_13565644 1.361 FBLN2
fibulin 2
chr3_-_50515857 1.361 NM_001005505
NM_001174051
NM_006030
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr1_-_218168548 1.361 NM_018713
SLC30A10
solute carrier family 30, member 10
chrX_-_8660132 1.360 KAL1
Kallmann syndrome 1 sequence
chr19_+_659766 1.355 NM_001040134
NM_002579
PALM

paralemmin

chr9_+_99656013 1.349


chr14_-_59113301 1.346 NM_001164399
C14orf38
chromosome 14 open reading frame 38
chr12_+_2774362 1.345 NM_002014
FKBP4
FK506 binding protein 4, 59kDa
chr5_+_3649167 1.335 NM_024337
IRX1
iroquois homeobox 1
chr22_-_22511173 1.335 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr17_+_40089270 1.332 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr7_+_100156358 1.324 NM_000799
EPO
erythropoietin
chr17_+_27617307 1.324 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr2_+_208979800 1.322 NM_005048
PTH2R
parathyroid hormone 2 receptor
chr22_-_37180958 1.321 NM_152868
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr4_+_77391876 1.319 NM_001136570
FAM47E
family with sequence similarity 47, member E
chr3_-_129694717 1.315 NM_032638
GATA2
GATA binding protein 2
chr10_+_50487146 1.309 NM_020984
CHAT
choline O-acetyltransferase
chr1_+_226937424 1.309 NM_021205
RHOU
ras homolog gene family, member U
chr17_+_56831951 1.302 NM_005994
TBX2
T-box 2
chr11_-_27678551 1.298 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr12_-_21818881 1.294 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr11_-_114880275 1.292 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.71 7.69e-21 GO:0048731 system development
3.63 3.30e-20 GO:0007399 nervous system development
2.52 2.37e-19 GO:0048856 anatomical structure development
2.41 5.02e-19 GO:0007275 multicellular organismal development
2.29 2.92e-18 GO:0032502 developmental process
1.98 2.08e-17 GO:0032501 multicellular organismal process
2.95 2.67e-17 GO:0030154 cell differentiation
2.87 1.56e-16 GO:0048869 cellular developmental process
3.96 4.80e-14 GO:0022008 neurogenesis
3.95 5.48e-13 GO:0048699 generation of neurons
4.79 4.15e-11 GO:0007417 central nervous system development
3.94 5.52e-10 GO:0030182 neuron differentiation
2.53 9.26e-10 GO:0048513 organ development
3.37 2.60e-09 GO:0048468 cell development
4.87 8.59e-08 GO:0007420 brain development
2.57 1.68e-07 GO:0009653 anatomical structure morphogenesis
1.45 5.64e-07 GO:0065007 biological regulation
1.82 8.42e-07 GO:0023052 signaling
1.50 9.75e-07 GO:0050794 regulation of cellular process
3.93 1.76e-06 GO:0019226 transmission of nerve impulse
3.93 1.76e-06 GO:0035637 multicellular organismal signaling
2.78 8.36e-06 GO:0007154 cell communication
3.12 8.37e-06 GO:0007267 cell-cell signaling
3.73 1.04e-05 GO:0000904 cell morphogenesis involved in differentiation
3.51 1.04e-05 GO:0048666 neuron development
3.92 1.55e-05 GO:0007268 synaptic transmission
1.43 2.09e-05 GO:0050789 regulation of biological process
3.63 3.53e-05 GO:0031175 neuron projection development
2.42 7.30e-05 GO:0051239 regulation of multicellular organismal process
3.08 2.76e-04 GO:0032989 cellular component morphogenesis
3.59 3.03e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
3.13 3.42e-04 GO:0000902 cell morphogenesis
3.52 4.07e-04 GO:0048812 neuron projection morphogenesis
2.68 4.73e-04 GO:0009888 tissue development
2.91 5.39e-04 GO:0009790 embryo development
4.52 6.67e-04 GO:0050767 regulation of neurogenesis
4.27 6.69e-04 GO:0051960 regulation of nervous system development
2.45 7.46e-04 GO:0010646 regulation of cell communication
2.78 8.03e-04 GO:2000026 regulation of multicellular organismal development
2.93 1.24e-03 GO:0030030 cell projection organization
2.01 1.60e-03 GO:0007166 cell surface receptor linked signaling pathway
3.81 1.60e-03 GO:0007411 axon guidance
2.53 1.61e-03 GO:0050793 regulation of developmental process
5.12 1.95e-03 GO:0030900 forebrain development
1.84 2.02e-03 GO:0048519 negative regulation of biological process
5.50 2.35e-03 GO:0045165 cell fate commitment
2.44 2.51e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.38 2.69e-03 GO:0007409 axonogenesis
2.05 2.79e-03 GO:0023051 regulation of signaling
3.13 2.91e-03 GO:0048858 cell projection morphogenesis
3.24 2.96e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.76 3.21e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.10 3.35e-03 GO:0032990 cell part morphogenesis
3.76 3.80e-03 GO:0060284 regulation of cell development
3.69 4.99e-03 GO:0051093 negative regulation of developmental process
1.85 5.16e-03 GO:0048523 negative regulation of cellular process
1.73 6.60e-03 GO:0031326 regulation of cellular biosynthetic process
2.36 7.02e-03 GO:0032879 regulation of localization
1.62 7.54e-03 GO:0007165 signal transduction
1.71 8.80e-03 GO:0051171 regulation of nitrogen compound metabolic process
3.37 8.88e-03 GO:0060429 epithelium development
1.72 9.53e-03 GO:0009889 regulation of biosynthetic process
2.59 1.13e-02 GO:0051049 regulation of transport
2.65 1.15e-02 GO:0045595 regulation of cell differentiation
2.86 1.26e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
5.11 1.26e-02 GO:0001655 urogenital system development
3.77 1.42e-02 GO:0035295 tube development
1.79 1.74e-02 GO:0006355 regulation of transcription, DNA-dependent
2.34 2.25e-02 GO:0006811 ion transport
5.85 2.73e-02 GO:0051924 regulation of calcium ion transport
1.56 3.17e-02 GO:0031323 regulation of cellular metabolic process
5.74 3.19e-02 GO:0001822 kidney development
3.72 3.21e-02 GO:0045596 negative regulation of cell differentiation
9.75 3.55e-02 GO:0001656 metanephros development
1.56 3.59e-02 GO:0080090 regulation of primary metabolic process
6.50 3.61e-02 GO:0042063 gliogenesis
3.29 3.83e-02 GO:0007389 pattern specification process
2.64 4.18e-02 GO:0009887 organ morphogenesis
5.52 4.34e-02 GO:0072001 renal system development
2.97 4.83e-02 GO:0060341 regulation of cellular localization
2.96 5.00e-02 GO:0006873 cellular ion homeostasis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.07 1.28e-06 GO:0043005 neuron projection
4.53 4.05e-06 GO:0044456 synapse part
3.87 6.81e-06 GO:0045202 synapse
2.01 7.84e-06 GO:0044459 plasma membrane part
1.57 3.00e-04 GO:0005886 plasma membrane
1.55 5.73e-04 GO:0071944 cell periphery
4.78 7.06e-04 GO:0030424 axon
2.38 2.02e-03 GO:0042995 cell projection
6.84 4.10e-03 GO:0033267 axon part
2.63 4.90e-03 GO:0030054 cell junction
9.75 5.87e-03 GO:0043679 axon terminus
1.35 6.17e-03 GO:0044425 membrane part
4.13 7.17e-03 GO:0030425 dendrite
9.29 7.82e-03 GO:0044306 neuron projection terminus
3.06 8.99e-03 GO:0031012 extracellular matrix
11.21 1.38e-02 GO:0034704 calcium channel complex
5.76 4.03e-02 GO:0014069 postsynaptic density

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.51 2.56e-08 GO:0043565 sequence-specific DNA binding
2.80 5.53e-07 GO:0030528 transcription regulator activity
2.71 3.36e-06 GO:0001071 nucleic acid binding transcription factor activity
2.71 3.36e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
4.11 5.66e-05 GO:0022836 gated channel activity
3.53 1.60e-04 GO:0022838 substrate-specific channel activity
3.42 2.62e-04 GO:0015267 channel activity
3.42 2.72e-04 GO:0022803 passive transmembrane transporter activity
3.41 4.95e-04 GO:0005216 ion channel activity
3.70 3.83e-03 GO:0005261 cation channel activity
5.20 5.85e-03 GO:0015276 ligand-gated ion channel activity
5.20 5.85e-03 GO:0022834 ligand-gated channel activity
4.17 8.40e-03 GO:0005244 voltage-gated ion channel activity
4.17 8.40e-03 GO:0022832 voltage-gated channel activity
4.50 8.97e-03 GO:0008083 growth factor activity
12.50 1.03e-02 GO:0005245 voltage-gated calcium channel activity
11.61 1.50e-02 GO:0008066 glutamate receptor activity
4.58 1.74e-02 GO:0022843 voltage-gated cation channel activity
2.20 2.01e-02 GO:0022891 substrate-specific transmembrane transporter activity
2.30 2.56e-02 GO:0015075 ion transmembrane transporter activity
15.29 2.73e-02 GO:0004970 ionotropic glutamate receptor activity
14.44 3.47e-02 GO:0005234 extracellular-glutamate-gated ion channel activity
5.91 4.47e-02 GO:0005262 calcium channel activity