Motif ID: NFATC1..3.p2

Z-value: 2.035


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3



Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_150533948 2.113 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_+_24518398 1.836 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr1_-_203657803 1.794 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr6_-_2580296 1.683 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr4_-_77147625 1.649 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr11_+_113280727 1.630 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr10_-_116434364 1.620 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr18_-_51219880 1.604 TCF4
transcription factor 4
chr2_+_69055208 1.602 NM_019617
GKN1
gastrokine 1
chr2_+_178893216 1.596 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr5_+_38481392 1.571 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr6_-_132980901 1.555 NM_014626
TAAR2
trace amine associated receptor 2
chr1_+_24518501 1.489 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr4_-_100575313 1.438 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr11_-_85115105 1.408 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr12_+_32578513 1.404 FGD4
FYVE, RhoGEF and PH domain containing 4
chr8_-_134141586 1.361 NM_006748
SLA
Src-like-adaptor
chr11_-_124311512 1.331 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr18_+_18989786 1.274 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr18_+_27281729 1.265 NM_001944
DSG3
desmoglein 3
chr4_+_154397975 1.240 TRIM2
tripartite motif containing 2
chr1_-_68470585 1.229 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chrX_+_10084984 1.217 NM_001830
CLCN4
chloride channel 4
chr11_-_35503720 1.201 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr10_-_116434102 1.182 ABLIM1
actin binding LIM protein 1
chr1_+_183970093 1.165 NM_031935
HMCN1
hemicentin 1
chr10_-_51678318 1.148 NM_001143974
NM_019893
ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

chr4_-_141293572 1.146 MAML3
mastermind-like 3 (Drosophila)
chr2_+_66519949 1.142 MEIS1
Meis homeobox 1
chr11_-_102219450 1.128 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_+_52733927 1.120 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr3_+_189425886 1.116 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr21_+_38550739 1.114 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_159386007 1.096 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr2_+_113601616 1.096 IL1RN
interleukin 1 receptor antagonist
chr8_-_125649926 1.093 MTSS1
metastasis suppressor 1
chr6_-_128883125 1.088 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr1_-_155936904 1.086 NM_052939
FCRL3
Fc receptor-like 3
chr6_-_2785682 1.081 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr1_+_144004589 1.066 NM_001039703
NBPF10
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 8
chr3_+_46594079 1.064 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr11_-_110888273 1.064 NM_017589
BTG4
B-cell translocation gene 4
chr4_+_76700281 1.052 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr1_-_150564302 1.043 NM_002016
FLG
filaggrin
chr1_+_169484256 1.041 NM_002021
FMO1
flavin containing monooxygenase 1
chr6_+_106653429 1.038 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr14_+_64240996 1.028 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_-_36469869 1.028 NM_001165252
LOC730755
keratin associated protein 2-4-like
chrX_+_2680092 1.024 NM_001141919
NM_001141920
NM_175569
XGPY2
XG


Xg pseudogene, Y-linked 2
Xg blood group


chr16_-_20495126 0.995 NM_001105069
NM_182617
ACSM2B

acyl-CoA synthetase medium-chain family member 2B

chr6_-_169395847 0.991 THBS2
thrombospondin 2
chr2_-_134042500 0.988 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr3_-_71715431 0.988 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr1_-_229627412 0.984 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr5_+_145296313 0.981 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr18_+_3443771 0.975 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr9_+_88953378 0.968 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr17_+_29670171 0.967 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr3_-_152529999 0.965 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr1_+_207926172 0.959 NM_181755
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr12_+_26239755 0.958 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr1_+_245646080 0.948 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr3_+_161040439 0.943 SCHIP1
schwannomin interacting protein 1
chr7_-_16811131 0.943 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr2_+_113601608 0.940 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr1_+_98899734 0.938 NM_015976
NM_152238
SNX7

sorting nexin 7

chr4_+_77575276 0.922 NM_020859
SHROOM3
shroom family member 3
chr14_+_62740878 0.915 NM_020663
RHOJ
ras homolog gene family, member J
chr3_+_187866464 0.913 NM_000412
HRG
histidine-rich glycoprotein
chr4_+_109033868 0.907 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr7_-_99365178 0.907 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr16_+_20370359 0.902 NM_001010845
ACSM2A
acyl-CoA synthetase medium-chain family member 2A
chr13_+_109932934 0.886 COL4A2
collagen, type IV, alpha 2
chr21_-_38792173 0.884 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr1_+_24713396 0.882 RCAN3
RCAN family member 3
chr6_+_155579788 0.877 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_-_47117951 0.872 NM_025048
NM_153840
GPR110

G protein-coupled receptor 110

chr3_+_11269384 0.872 NM_000861
HRH1
histamine receptor H1
chr5_+_145297490 0.866 SH3RF2
SH3 domain containing ring finger 2
chr11_+_5597749 0.865 NM_001003827
TRIM34
tripartite motif containing 34
chr1_-_109201228 0.860 NM_152763
AKNAD1
AKNA domain containing 1
chr16_+_70654625 0.860 NM_020995
HPR
haptoglobin-related protein
chr12_+_48310593 0.858 NM_001031698
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr4_+_111053488 0.854 NM_001178130
NM_001178131
NM_001963
EGF


epidermal growth factor


chr1_-_205272619 0.853 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr8_-_116750427 0.839 TRPS1
trichorhinophalangeal syndrome I
chr1_+_169421011 0.839 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr11_-_5247948 0.828 NM_005330
HBE1
hemoglobin, epsilon 1
chr13_-_32822759 0.828 STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_+_120416680 0.828 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr19_+_60006877 0.825 NM_001080770
NM_001080772
NM_002255
KIR2DL4


killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4


chr11_+_20005704 0.823 NAV2
neuron navigator 2
chr15_+_37330176 0.823 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr11_-_8849485 0.819 ST5
suppression of tumorigenicity 5
chr2_-_37269193 0.815 NM_001032377
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr11_-_110917632 0.814


chr15_+_69626594 0.814 THSD4
thrombospondin, type I, domain containing 4
chr10_+_69539255 0.807 NM_032578
MYPN
myopalladin
chr11_+_118259684 0.802 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr1_+_66772393 0.802 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_-_27133163 0.801 NM_153631
HOXA3
homeobox A3
chr22_+_31526801 0.797 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr1_-_116184846 0.796 NM_001111061
NHLH2
nescient helix loop helix 2
chr20_+_12937616 0.792 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr12_+_13240983 0.788 EMP1
epithelial membrane protein 1
chr4_-_177427252 0.787 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr12_-_66839589 0.784 NM_000619
IFNG
interferon, gamma
chr17_-_36347197 0.777 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_13240987 0.769 EMP1
epithelial membrane protein 1
chr6_-_134680888 0.769 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr16_+_67130616 0.768 ZFP90
zinc finger protein 90 homolog (mouse)
chr4_-_87593306 0.763 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr11_-_102001259 0.762 NM_004771
MMP20
matrix metallopeptidase 20
chr17_+_29606408 0.759 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr3_-_9265592 0.754 SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr7_+_80069439 0.752 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr12_-_51153788 0.744 NM_173086
KRT6C
keratin 6C
chr6_+_152053323 0.742 NM_001122742
ESR1
estrogen receptor 1
chr14_-_105644300 0.731 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr4_+_152549776 0.725 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr12_-_28016182 0.724 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr17_-_64108843 0.724 FAM20A
family with sequence similarity 20, member A
chr12_+_9925354 0.724 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr1_-_161379606 0.724 RGS5
regulator of G-protein signaling 5
chr12_+_121885246 0.722 HIP1R
huntingtin interacting protein 1 related
chr3_-_194118321 0.720 MB21D2
Mab-21 domain containing 2
chr11_+_36572615 0.718 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr4_+_154083584 0.714 NM_033393
FHDC1
FH2 domain containing 1
chr4_-_120445047 0.707 NM_001170330
C4orf3
chromosome 4 open reading frame 3
chr3_-_152403636 0.706 NM_013308
GPR171
G protein-coupled receptor 171
chr4_-_152366970 0.706 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chr7_+_28305464 0.704 NM_182899
CREB5
cAMP responsive element binding protein 5
chr1_+_171871283 0.702 NM_001195190
LOC730159
hypothetical protein LOC730159
chr6_-_89984214 0.701 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr12_+_39372456 0.700 NM_001843
NM_175038
CNTN1

contactin 1

chr5_+_55182963 0.700 NM_139017
IL31RA
interleukin 31 receptor A
chr3_-_9266251 0.697 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr10_-_94247450 0.696 NM_001165946
IDE
insulin-degrading enzyme
chr12_-_49708279 0.694 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr14_-_106193403 0.683 IGKV3-20
immunoglobulin kappa variable 3-20
chr3_-_162572441 0.683 NM_001040100
C3orf57
chromosome 3 open reading frame 57
chr12_-_52980914 0.683 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr18_+_7936885 0.682 PTPRM
protein tyrosine phosphatase, receptor type, M
chr3_-_18455207 0.679 NM_001131010
SATB1
SATB homeobox 1
chr4_-_87989291 0.679 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr16_-_80602546 0.678 NM_145168
SDR42E1
short chain dehydrogenase/reductase family 42E, member 1
chr9_+_102380156 0.678 NM_001018116
MURC
muscle-related coiled-coil protein
chr1_+_205105776 0.677 NM_018724
IL20
interleukin 20
chr6_+_31081707 0.677 NM_001198815
PBMUCL1
panbronchiolitis related mucin-like 1
chr15_+_69220841 0.674 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chr1_+_78888064 0.668 NM_006417
IFI44
interferon-induced protein 44
chr14_-_20098929 0.666 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr6_-_169395972 0.664 NM_003247
THBS2
thrombospondin 2
chr4_+_71283383 0.663 NM_006685
SMR3B
submaxillary gland androgen regulated protein 3B
chr1_+_157246305 0.663 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr9_-_116920232 0.660 NM_002160
TNC
tenascin C
chr4_+_124537334 0.656 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_-_150993299 0.655 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr8_-_82522175 0.650 NM_002677
PMP2
peripheral myelin protein 2
chr4_-_186934059 0.647 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr8_-_124613557 0.645 NM_148177
FBXO32
F-box protein 32
chr3_-_124893875 0.640 MYLK
myosin light chain kinase
chr20_+_42644633 0.640 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr3_+_152934393 0.638 NM_207365
AADACL2
arylacetamide deacetylase-like 2
chr1_-_171286634 0.637 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr12_+_106692291 0.623 NM_203436
ASCL4
achaete-scute complex homolog 4 (Drosophila)
chr12_+_26239535 0.623 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr8_-_81155564 0.622 NM_001025252
TPD52
tumor protein D52
chr4_+_152417774 0.622 NM_183375
PRSS48
protease, serine, 48
chr20_+_51235228 0.622 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr12_+_13240868 0.620 NM_001423
EMP1
epithelial membrane protein 1
chr9_+_676640 0.617


chr8_-_82606104 0.616 NM_001105281
FABP12
fatty acid binding protein 12
chr6_-_33028790 0.616 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr1_-_120240635 0.615 NM_021794
ADAM30
ADAM metallopeptidase domain 30
chr8_-_49996353 0.613 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr3_+_50119261 0.613 RBM5
RNA binding motif protein 5
chr4_-_164473107 0.612 NM_000909
NPY1R
neuropeptide Y receptor Y1
chr7_-_105106844 0.606 NM_138495
ATXN7L1
ataxin 7-like 1
chr6_+_39868770 0.605 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr4_+_40032146 0.604 NM_017581
CHRNA9
cholinergic receptor, nicotinic, alpha 9
chr7_-_48035169 0.602 NM_001030019
NM_152782
SUN3

Sad1 and UNC84 domain containing 3

chr12_-_10215942 0.599 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr4_-_149582754 0.598 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr7_+_111850367 0.597 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr10_+_124141808 0.596 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr4_+_120029426 0.596 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr5_-_37220702 0.593 C5orf42
chromosome 5 open reading frame 42
chr1_-_149698516 0.591 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr9_+_35528890 0.588 RUSC2
RUN and SH3 domain containing 2
chr5_-_59100091 0.587 PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_145699308 0.585 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chr7_+_22733626 0.581 IL6
interleukin 6 (interferon, beta 2)
chr10_+_114033403 0.579 NM_058222
TECTB
tectorin beta
chr11_+_58888460 0.576 NM_001004729
OR5AN1
olfactory receptor, family 5, subfamily AN, member 1
chr1_+_156416360 0.576 NM_001766
CD1D
CD1d molecule
chr18_+_19523402 0.575 LAMA3
laminin, alpha 3
chr5_-_125956996 0.574 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr12_-_94469357 0.568 NM_032147
USP44
ubiquitin specific peptidase 44
chr7_+_115952074 0.566 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.