Motif ID: NFE2.p2

Z-value: 0.922


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa



Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_56445653 1.352 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr18_+_19706979 1.236 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr16_+_56219802 1.180 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr16_-_3025542 1.037 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr4_-_77163609 1.025 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr1_-_119333701 0.954 NM_152380
TBX15
T-box 15
chr8_-_26778832 0.901 NM_000680
NM_033302
NM_033303
NM_033304
ADRA1A



adrenergic, alpha-1A-, receptor



chr22_+_19699441 0.844 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr12_+_54361685 0.842 METTL7B
methyltransferase like 7B
chr2_-_113752957 0.834 NM_003466
NM_013952
NM_013953
NM_013992
PAX8



paired box 8



chr19_-_4510713 0.814 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr5_+_176807931 0.811 NM_001174102
PRR7
proline rich 7 (synaptic)
chr13_+_51334117 0.794 NM_031290
CCDC70
coiled-coil domain containing 70
chr6_-_41781655 0.792 TFEB
transcription factor EB
chr21_+_29439768 0.792 C21orf7
chromosome 21 open reading frame 7
chr16_-_70763849 0.764 NM_001160213
PMFBP1
polyamine modulated factor 1 binding protein 1
chr4_+_120276386 0.760 NM_016599
MYOZ2
myozenin 2
chr10_-_31328426 0.752 NM_001143769
ZNF438
zinc finger protein 438
chr2_+_74595073 0.737 NM_016170
TLX2
T-cell leukemia homeobox 2
chr19_-_40673185 0.730 NM_207392
KRTDAP
keratinocyte differentiation-associated protein
chr3_+_185377341 0.721 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_24311212 0.717 NM_152372
MYOM3
myomesin family, member 3
chrX_-_15593074 0.713 NM_020665
TMEM27
transmembrane protein 27
chr17_+_45965076 0.701 EPN3
epsin 3
chr17_-_36834183 0.697 NM_003770
KRT37
keratin 37
chr9_+_102231616 0.680 NM_001198806
C9orf30
chromosome 9 open reading frame 30
chr1_+_229365296 0.666 NM_001004342
TRIM67
tripartite motif containing 67
chr5_-_141041982 0.663 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr4_+_154397975 0.654 TRIM2
tripartite motif containing 2
chr5_+_145297490 0.648 SH3RF2
SH3 domain containing ring finger 2
chr19_-_53935648 0.647 NM_017805
RASIP1
Ras interacting protein 1
chr3_+_57069508 0.644 NM_181727
SPATA12
spermatogenesis associated 12
chr1_+_24522116 0.642 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_925332 0.623 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr18_+_19947314 0.611 TTC39C
tetratricopeptide repeat domain 39C
chr8_+_24827181 0.598 NEFM
neurofilament, medium polypeptide
chr17_-_202557 0.594 RPH3AL
rabphilin 3A-like (without C2 domains)
chr8_+_24827173 0.593 NM_005382
NEFM
neurofilament, medium polypeptide
chr13_+_77007809 0.583 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr8_-_143820825 0.576 NM_020427
SLURP1
secreted LY6/PLAUR domain containing 1
chr22_+_21042091 0.573 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr3_+_185377430 0.570 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_925215 0.568 HES4
hairy and enhancer of split 4 (Drosophila)
chr15_+_57691382 0.567 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr17_+_77910411 0.566 NM_207459
TEX19
testis expressed 19
chr18_+_29573152 0.565 ASXL3
additional sex combs like 3 (Drosophila)
chr12_+_54361596 0.562 NM_152637
METTL7B
methyltransferase like 7B
chr22_+_20899155 0.559


chrX_+_99786044 0.553 SRPX2
sushi-repeat containing protein, X-linked 2
chr15_+_57691272 0.551 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr9_-_96442377 0.545 FBP1
fructose-1,6-bisphosphatase 1
chr1_+_12698704 0.541 NM_001103169
NM_001103170
AADACL3

arylacetamide deacetylase-like 3

chr6_-_149847718 0.539 ZC3H12D
zinc finger CCCH-type containing 12D
chr11_+_67107641 0.537 NM_000852
GSTP1
glutathione S-transferase pi 1
chr16_-_1369613 0.535 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr5_-_141041933 0.534 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr9_-_96442351 0.531 NM_001127628
FBP1
fructose-1,6-bisphosphatase 1
chr16_-_27806978 0.528 NM_144675
GSG1L
GSG1-like
chr3_+_134976965 0.527 TF
transferrin
chrX_-_10761729 0.525 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr9_-_115880494 0.515 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880281 0.514 AMBP
alpha-1-microglobulin/bikunin precursor
chrX_-_16640590 0.510 NM_175859
NM_019857
CTPS2

CTP synthase II

chrX_+_133198742 0.508 NM_001101357
CCDC160
coiled-coil domain containing 160
chr7_-_98305599 0.504 NM_001134450
NM_001134451
NM_152913
TMEM130


transmembrane protein 130


chr6_-_29563657 0.503 NM_052967
MAS1L
MAS1 oncogene-like
chr12_+_76749199 0.502 NM_014903
NAV3
neuron navigator 3
chr17_-_202617 0.501 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr19_+_12810258 0.500 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chrX_-_24575375 0.498 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr17_+_22823151 0.494 NM_014238
KSR1
kinase suppressor of ras 1
chr16_-_70763524 0.490 NM_031293
PMFBP1
polyamine modulated factor 1 binding protein 1
chr19_+_43971689 0.488 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr5_-_35083996 0.485 NM_031900
AGXT2
alanine--glyoxylate aminotransferase 2
chr2_-_169596078 0.484 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr1_-_6474346 0.484 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chrX_+_69314060 0.478 NM_198512
DGAT2L6
diacylglycerol O-acyltransferase 2-like 6
chr3_-_48607596 0.478 NM_000094
COL7A1
collagen, type VII, alpha 1
chr1_+_81544432 0.477 LPHN2
latrophilin 2
chr1_-_11841476 0.475 NM_002521
NPPB
natriuretic peptide B
chrX_-_2896285 0.475 ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr16_-_2848106 0.467 NM_022119
PRSS22
protease, serine, 22
chr4_+_152549776 0.463 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr6_+_31190505 0.462 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr22_+_18388656 0.461 C22orf25
chromosome 22 open reading frame 25
chr8_-_131483395 0.460 NM_018482
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr3_+_189413414 0.454 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_+_51091822 0.453 NM_153183
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr10_+_47867667 0.449 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chrX_-_24575146 0.449 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr9_-_115880366 0.447 AMBP
alpha-1-microglobulin/bikunin precursor
chr2_-_89400935 0.447 IGKC
immunoglobulin kappa constant
chr8_-_81949570 0.447 NM_001033723
ZNF704
zinc finger protein 704
chr9_-_115880425 0.446 AMBP
alpha-1-microglobulin/bikunin precursor
chr2_-_73170290 0.443 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr19_+_46640902 0.433 NM_001130514
C19orf69
chromosome 19 open reading frame 69
chr7_+_142768916 0.433 ZYX
zyxin
chr1_+_17404206 0.431 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr19_-_55914837 0.431


chr16_+_2023279 0.430 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_-_197549588 0.429 TM4SF19
transmembrane 4 L six family member 19
chr1_+_31855873 0.428 NM_001525
HCRTR1
hypocretin (orexin) receptor 1
chr2_-_219881937 0.428 PTPRN
protein tyrosine phosphatase, receptor type, N
chr8_+_22900863 0.425 NM_001160036
RHOBTB2
Rho-related BTB domain containing 2
chr1_-_244647333 0.425 NM_022743
SMYD3
SET and MYND domain containing 3
chr17_-_36850978 0.424 NM_006771
KRT38
keratin 38
chr21_-_36774257 0.424 NM_001146079
NM_144492
CLDN14

claudin 14

chr9_-_103237851 0.423 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr7_-_98305551 0.421 TMEM130
transmembrane protein 130
chrX_-_53327473 0.420 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr12_-_51153788 0.415 NM_173086
KRT6C
keratin 6C
chr6_-_149847809 0.414 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr1_+_148747110 0.414 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr16_-_30032330 0.412 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr10_-_81698840 0.412 NM_003019
SFTPD
surfactant protein D
chr1_+_181421984 0.409 LAMC2
laminin, gamma 2
chr15_+_84021271 0.406 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr4_+_183302105 0.406 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chrX_-_19727828 0.402 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr6_+_41712907 0.401 MDFI
MyoD family inhibitor
chr3_+_156280129 0.398 NM_000902
MME
membrane metallo-endopeptidase
chr9_-_139068269 0.396 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr1_-_117554999 0.393 NM_024626
VTCN1
V-set domain containing T cell activation inhibitor 1
chr18_+_59405513 0.393 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr9_-_99974994 0.393 NM_003389
CORO2A
coronin, actin binding protein, 2A
chr15_+_72315719 0.391 NM_025055
CCDC33
coiled-coil domain containing 33
chr19_-_43926953 0.391 NM_144691
CAPN12
calpain 12
chr22_+_21393107 0.387 IGLJ3
immunoglobulin lambda joining 3
chr10_-_46601687 0.385 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr1_+_17507276 0.383 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr22_+_43451600 0.382 PRR5
proline rich 5 (renal)
chr8_-_95289945 0.382 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr20_+_34206070 0.376 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr10_+_77212524 0.374 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr1_-_67039518 0.374 NM_005478
INSL5
insulin-like 5
chr4_+_74825138 0.374 NM_000584
IL8
interleukin 8
chr18_+_59593591 0.371 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_+_1812115 0.366 NM_138567
SYT8
synaptotagmin VIII
chr1_-_151296611 0.366 NM_005988
SPRR2A
small proline-rich protein 2A
chr16_+_30903963 0.366 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr11_+_35640918 0.365 NM_017583
TRIM44
tripartite motif containing 44
chr8_+_22266256 0.365 PIWIL2
piwi-like 2 (Drosophila)
chr7_-_33047042 0.363 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr1_-_151614681 0.362 NM_005621
S100A12
S100 calcium binding protein A12
chr3_+_185386664 0.360 ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr8_+_144428083 0.356 GLI4
GLI family zinc finger 4
chr22_+_21011653 0.356


chr22_+_21340757 0.353


chr1_+_151025376 0.353 NM_178353
LCE1E
late cornified envelope 1E
chr7_+_154493478 0.352 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr9_+_35528890 0.352 RUSC2
RUN and SH3 domain containing 2
chr19_+_12996830 0.351 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr22_+_21065207 0.351 IGLJ3
immunoglobulin lambda joining 3
chr1_+_207668787 0.350 NM_001104548
LOC642587
NPC-A-5
chr3_-_58175437 0.350 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr4_-_174687104 0.350 HAND2
heart and neural crest derivatives expressed 2
chr1_-_205272619 0.350 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr3_-_13089547 0.349 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr11_-_47502115 0.347 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr7_+_95239753 0.345 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr18_+_30427279 0.344 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr11_-_6633427 0.343 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr2_-_85494639 0.342 CAPG
capping protein (actin filament), gelsolin-like
chr16_+_30326386 0.342 ZNF771
zinc finger protein 771
chr5_-_59100091 0.341 PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_+_21065202 0.341


chr1_+_148747208 0.340 ECM1
extracellular matrix protein 1
chr8_-_26780645 0.340


chr16_+_30326864 0.340 ZNF771
zinc finger protein 771
chr19_-_54350457 0.339 NM_002152
HRC
histidine rich calcium binding protein
chr2_-_85494664 0.338 CAPG
capping protein (actin filament), gelsolin-like
chr22_+_43451351 0.336 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr22_+_21065134 0.334 LOC100290481
immunoglobulin lambda light chain-like
chrX_-_152863251 0.333 NM_002910
RENBP
renin binding protein
chr3_-_197549640 0.332 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr8_-_125649926 0.330 MTSS1
metastasis suppressor 1
chr3_+_187840842 0.330 NM_014375
FETUB
fetuin B
chr3_+_154035425 0.330 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr7_-_5533621 0.329 ACTB
actin, beta
chr8_-_26780665 0.328 ADRA1A
adrenergic, alpha-1A-, receptor
chr11_+_118463906 0.328 NM_001024382
HMBS
hydroxymethylbilane synthase
chrX_-_19727775 0.327 SH3KBP1
SH3-domain kinase binding protein 1
chr17_+_29606408 0.327 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chrX_-_39921525 0.325 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr11_-_46364681 0.324 NM_000741
CHRM4
cholinergic receptor, muscarinic 4
chr19_+_61039755 0.324 NM_134444
NLRP4
NLR family, pyrin domain containing 4
chr1_-_159257567 0.323 F11R
F11 receptor
chr2_-_215967442 0.322 FN1
fibronectin 1
chr1_+_15128882 0.322 NM_001018001
KAZN
kazrin, periplakin interacting protein
chrX_+_99785818 0.321 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr3_-_193609531 0.320 NM_021032
FGF12
fibroblast growth factor 12
chr9_-_26937435 0.315 NM_001031689
PLAA
phospholipase A2-activating protein
chr19_+_12996745 0.315 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_-_80548378 0.312 NM_033214
GK2
glycerol kinase 2
chr6_+_74462226 0.311 NM_001159587
NM_001159588
NM_133493
CD109


CD109 molecule


chr1_-_159257486 0.309 F11R
F11 receptor
chr11_+_48194937 0.308 NM_001005470
OR4B1
olfactory receptor, family 4, subfamily B, member 1
chr16_+_66128843 0.307 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr10_-_30064600 0.307 NM_003174
SVIL
supervillin
chr8_-_13018123 0.305 NM_001164271
DLC1
deleted in liver cancer 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.