Motif ID: NFE2L2.p2

Z-value: 1.228


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2



Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_21340757 4.666


chr22_+_21484240 4.665


chr7_+_116099648 3.608 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr22_+_21370394 2.701 IGL@
immunoglobulin lambda locus
chr1_-_24307514 2.667 MYOM3
myomesin family, member 3
chr5_+_150000394 2.319 NM_001109974
NM_007286
SYNPO

synaptopodin

chr18_+_19706979 2.316 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr22_+_21393107 2.233 IGLJ3
immunoglobulin lambda joining 3
chr22_+_21407066 2.185


chr22_+_21011653 2.092


chr22_+_21495273 2.047


chr22_+_21359175 2.006 IGLV3-25
immunoglobulin lambda variable 3-25
chr11_+_72660894 1.977 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr22_+_21094094 1.947


chr20_+_34206070 1.916 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr22_+_20899155 1.848


chr22_+_21053972 1.791


chr17_-_45619038 1.731 COL1A1
collagen, type I, alpha 1
chr22_+_20316968 1.670 NM_152612
CCDC116
coiled-coil domain containing 116
chr4_-_84152985 1.635 NM_001115007
LIN54
lin-54 homolog (C. elegans)
chr22_+_21116283 1.613


chr11_-_6298284 1.599 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr22_+_21042091 1.582 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr17_-_37022465 1.553 NM_005557
KRT16
keratin 16
chr20_+_44070946 1.532 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr9_+_124602190 1.464 NM_080859
OR1K1
olfactory receptor, family 1, subfamily K, member 1
chr6_-_35804337 1.428 NM_001145775
FKBP5
FK506 binding protein 5
chr22_+_21065134 1.415 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21065202 1.384


chr2_-_99238001 1.382 NM_175735
LYG2
lysozyme G-like 2
chr7_+_139175420 1.347 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr6_-_21631992 1.339


chr19_+_56337368 1.335 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr14_-_21108714 1.319 NM_001005465
OR10G3
olfactory receptor, family 10, subfamily G, member 3
chr22_+_21065207 1.319 IGLJ3
immunoglobulin lambda joining 3
chr2_-_70901186 1.287 NM_173535
CLEC4F
C-type lectin domain family 4, member F
chr22_+_21006814 1.284


chr10_+_85889164 1.278 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr1_+_17571277 1.251 NM_207421
PADI6
peptidyl arginine deiminase, type VI
chr22_-_17846621 1.245 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr19_-_56279278 1.245 NM_022046
KLK14
kallikrein-related peptidase 14
chr22_+_21079355 1.235


chr18_+_19947314 1.228 TTC39C
tetratricopeptide repeat domain 39C
chr7_+_130445394 1.223 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr6_+_41712907 1.208 MDFI
MyoD family inhibitor
chr1_-_6474346 1.208 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_+_221955876 1.203 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr11_+_118463906 1.202 NM_001024382
HMBS
hydroxymethylbilane synthase
chr2_+_132890616 1.200 NM_001508
GPR39
G protein-coupled receptor 39
chr22_+_18388656 1.184 C22orf25
chromosome 22 open reading frame 25
chr1_-_7923464 1.144 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr17_-_36877002 1.139 NM_002278
KRT32
keratin 32
chr9_+_94776538 1.121 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr1_+_158426908 1.118 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_-_191143017 1.108 NM_020040
TUBB4Q
tubulin, beta polypeptide 4, member Q
chr14_+_22422270 1.108 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chrX_+_100361588 1.108 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr12_-_55316350 1.105 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr22_+_21559959 1.092 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr2_+_37282516 1.088 LOC100505876
hypothetical LOC100505876
chr13_+_112746908 1.083 MCF2L
MCF.2 cell line derived transforming sequence-like
chr16_+_55199978 1.078 NM_005953
MT2A
metallothionein 2A
chrX_+_153423652 1.044 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr10_-_85154 1.038 NM_177987
TUBB8
tubulin, beta 8
chr22_+_19699441 1.027 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr8_-_131483395 1.012 NM_018482
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_+_3378030 0.987 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_+_11153778 0.976 NM_001098213
HRH1
histamine receptor H1
chr9_+_129962292 0.975 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr2_+_54195913 0.975 NM_138448
ACYP2
acylphosphatase 2, muscle type
chr5_+_140848905 0.959 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr22_-_17846711 0.955 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr6_-_139654807 0.953 NM_153235
TXLNB
taxilin beta
chr4_+_169989680 0.951 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr22_-_17846725 0.937 NM_001035247
NM_005659
UFD1L

ubiquitin fusion degradation 1 like (yeast)

chr16_+_27346079 0.935 NM_021798
IL21R
interleukin 21 receptor
chr4_-_26100986 0.930 NM_000730
CCKAR
cholecystokinin A receptor
chr17_-_36587965 0.927 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr1_-_115039614 0.926 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr1_+_17404206 0.925 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr3_-_46582806 0.924 NM_024512
LRRC2
leucine rich repeat containing 2
chr14_+_38772870 0.919 NM_054024
MIA2
melanoma inhibitory activity 2
chr4_+_39376058 0.899 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)


chr8_-_38505331 0.894 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr7_+_129720209 0.892 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr14_-_22658078 0.881 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr16_+_56219802 0.873 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr7_+_1050704 0.873


chr22_+_21552897 0.871 LOC100290481
immunoglobulin lambda light chain-like
chr7_+_150065376 0.862 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr4_+_108965167 0.860 NM_001136258
SGMS2
sphingomyelin synthase 2
chr19_+_53747233 0.854 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr1_+_152644668 0.833 IL6R
interleukin 6 receptor
chr7_+_150065594 0.819 GIMAP5
GTPase, IMAP family member 5
chr7_+_93388951 0.818 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr1_-_45760115 0.816 NM_002574
NM_181696
NM_181697
PRDX1


peroxiredoxin 1


chr6_-_31853027 0.816 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr16_+_88696172 0.802 FAM157C
family with sequence similarity 157, member C
chr8_-_145097031 0.801 NM_201380
PLEC
plectin
chr4_+_76700281 0.787 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr7_-_150352484 0.740 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr12_+_49080858 0.726 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr2_-_11523727 0.703 NM_198256
E2F6
E2F transcription factor 6
chr9_+_676640 0.701


chr6_-_24985432 0.695 NM_015864
FAM65B
family with sequence similarity 65, member B
chr2_-_11523666 0.678 E2F6
E2F transcription factor 6
chr16_+_76613912 0.676 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr9_+_102231616 0.675 NM_001198806
C9orf30
chromosome 9 open reading frame 30
chr19_-_59258846 0.673 NM_198481
VSTM1
V-set and transmembrane domain containing 1
chr10_-_31328426 0.671 NM_001143769
ZNF438
zinc finger protein 438
chr19_-_61039939 0.671 NM_145007
NLRP11
NLR family, pyrin domain containing 11
chr7_-_76667045 0.666 NM_006682
FGL2
fibrinogen-like 2
chr1_-_33139425 0.664 NM_033504
TMEM54
transmembrane protein 54
chrX_+_133198742 0.658 NM_001101357
CCDC160
coiled-coil domain containing 160
chr17_+_71229151 0.655 ITGB4
integrin, beta 4
chr21_+_38566298 0.654 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_+_31190505 0.650 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr17_-_36533903 0.643 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr10_+_18138338 0.640 NM_001009567
NM_002438
MRC1L1
MRC1
mannose receptor, C type 1-like 1
mannose receptor, C type 1
chr8_+_87424074 0.638 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr16_+_79132354 0.637 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr18_+_19848749 0.632 TTC39C
tetratricopeptide repeat domain 39C
chr3_+_14835472 0.629 NM_152536
FGD5
FYVE, RhoGEF and PH domain containing 5
chr11_+_5916033 0.625


chr17_+_64922420 0.621 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_22224571 0.616 HSPC157
hypothetical LOC29092
chr2_+_113591940 0.613 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr1_-_32036858 0.612 SPOCD1
SPOC domain containing 1
chrX_+_149282097 0.610 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr2_+_33213111 0.608 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr18_-_18251808 0.605 NM_172241
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr7_-_150561233 0.603


chr1_-_242073094 0.595 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr12_+_100512877 0.589 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr2_-_27967458 0.588 LOC100302650
hypothetical LOC100302650
chr17_+_25292748 0.578 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr22_+_20880159 0.578 IGLV6-57
immunoglobulin lambda variable 6-57
chr15_+_36776090 0.568 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr12_-_49897743 0.567 POU6F1
POU class 6 homeobox 1
chr7_+_157339985 0.565 LOC100506585
hypothetical LOC100506585
chr10_-_76538859 0.563 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr8_-_68821131 0.555 NM_020361
CPA6
carboxypeptidase A6
chr6_-_28999388 0.554 TRIM27
tripartite motif containing 27
chr17_+_71229110 0.534 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr22_+_21027538 0.531


chr16_+_30903963 0.526 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr17_+_44642587 0.526 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr22_+_16423147 0.524 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr12_-_51912101 0.524 NM_000966
RARG
retinoic acid receptor, gamma
chr16_-_1369613 0.520 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr6_-_24827265 0.515 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr7_+_1543644 0.508 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr14_-_105804211 0.503 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_+_42273013 0.503 LOC100505783
hypothetical LOC100505783
chr20_+_19903778 0.503 RIN2
Ras and Rab interactor 2
chr6_-_110843432 0.496 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr1_+_152644292 0.493 NM_000565
NM_181359
IL6R

interleukin 6 receptor

chr5_+_61750467 0.493 NM_001134779
IPO11
importin 11
chr22_-_43986896 0.491 KIAA0930
KIAA0930
chr1_+_46151845 0.488 MAST2
microtubule associated serine/threonine kinase 2
chr5_+_179180517 0.486 SQSTM1
sequestosome 1
chr19_-_8118367 0.480 NM_032447
FBN3
fibrillin 3
chr11_-_62539857 0.479 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr16_+_51690564 0.474 CHD9
chromodomain helicase DNA binding protein 9
chr3_+_130730171 0.473 NM_000539
RHO
rhodopsin
chr1_+_152644471 0.471 IL6R
interleukin 6 receptor
chr5_+_179180509 0.469 SQSTM1
sequestosome 1
chr5_-_54317102 0.462 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr5_-_158569067 0.462 RNF145
ring finger protein 145
chr11_+_10434056 0.457 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr16_+_54070302 0.455 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr7_-_102772304 0.453 NM_001129887
NM_014377
DNAJC2

DnaJ (Hsp40) homolog, subfamily C, member 2

chr12_+_54361685 0.449 METTL7B
methyltransferase like 7B
chr7_+_133862883 0.444 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr7_+_106991638 0.444 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr16_-_28528780 0.442 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr8_-_42742729 0.442 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr17_+_71229191 0.440 ITGB4
integrin, beta 4
chr22_-_18687511 0.438 NM_033257
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr3_-_39209075 0.433 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr1_+_27541049 0.432 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr1_-_146543102 0.427


chr3_+_46894239 0.421 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr3_+_112934016 0.419 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr2_-_61618165 0.416 XPO1
exportin 1 (CRM1 homolog, yeast)
chr6_-_138470160 0.412 NM_022121
PERP
PERP, TP53 apoptosis effector
chr10_-_13584950 0.410 NM_001100912
NM_152751
BEND7

BEN domain containing 7

chr19_-_60573552 0.409 NM_000641
IL11
interleukin 11
chr19_-_40696393 0.408 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr10_+_685887 0.407 C10orf108
chromosome 10 open reading frame 108
chr12_-_10173947 0.407 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr5_+_179180447 0.406 NM_003900
SQSTM1
sequestosome 1
chr6_+_31782618 0.405 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr1_-_94147537 0.405 GCLM
glutamate-cysteine ligase, modifier subunit
chr8_-_143820825 0.404 NM_020427
SLURP1
secreted LY6/PLAUR domain containing 1
chr18_+_19848347 0.401 NM_001135993
TTC39C
tetratricopeptide repeat domain 39C
chr16_+_82544327 0.397 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr4_-_174557191 0.395 NM_007281
SCRG1
stimulator of chondrogenesis 1
chr10_+_75202258 0.394 FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr12_+_63084317 0.391 NM_007235
XPOT
exportin, tRNA (nuclear export receptor for tRNAs)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.