Motif ID: NR5A1,2.p2

Z-value: 1.981


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2



Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_144649142 3.450 UTRN
utrophin
chr1_-_206263170 2.919 PLXNA2
plexin A2
chr12_-_13139848 2.900 NM_031289
NM_153823
GSG1

germ cell associated 1

chr19_+_54238913 2.892 NM_033043
CGB
CGB5
chorionic gonadotropin, beta polypeptide
chorionic gonadotropin, beta polypeptide 5
chr6_-_2785682 2.608 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_54244133 2.537 NM_033183
CGB
CGB5
CGB8
chorionic gonadotropin, beta polypeptide
chorionic gonadotropin, beta polypeptide 5
chorionic gonadotropin, beta polypeptide 8
chr8_-_18585721 2.393 PSD3
pleckstrin and Sec7 domain containing 3
chr19_-_54250808 2.392 NM_033142
CGB7
chorionic gonadotropin, beta polypeptide 7
chr12_+_50104936 2.389 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr5_+_73145098 2.257 RGNEF
190 kDa guanine nucleotide exchange factor
chr6_+_21701942 2.028 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr19_-_40711034 1.953 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr11_+_76491532 1.924 NM_006189
OMP
olfactory marker protein
chr3_+_14835472 1.916 NM_152536
FGD5
FYVE, RhoGEF and PH domain containing 5
chr1_+_15955719 1.826 FBLIM1
filamin binding LIM protein 1
chr19_-_54219039 1.749 NM_000737
CGB
CGB5
chorionic gonadotropin, beta polypeptide
chorionic gonadotropin, beta polypeptide 5
chr18_-_13905534 1.748 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr17_-_45626967 1.744


chr7_-_130891861 1.650 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr7_+_115953582 1.640 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr2_-_175578156 1.634 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr1_-_158091296 1.599 C1orf204
chromosome 1 open reading frame 204
chr20_+_57199469 1.598 NM_178457
ZNF831
zinc finger protein 831
chr1_+_31823097 1.594 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr5_-_112798436 1.576 NM_032028
TSSK1B
testis-specific serine kinase 1B
chr1_+_160618143 1.571 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr22_+_21370394 1.549 IGL@
immunoglobulin lambda locus
chr22_+_19239221 1.516 MED15
mediator complex subunit 15
chr5_+_52320660 1.470 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chrX_-_107112244 1.453 NM_031273
TEX13B
testis expressed 13B
chr12_-_109842736 1.430 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr16_-_66007650 1.426 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr3_+_3056307 1.412 NM_175612
CNTN4
contactin 4
chr9_+_132961723 1.386 AIF1L
allograft inflammatory factor 1-like
chr22_+_19458378 1.378 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr8_+_143758875 1.346 NM_005672
PSCA
prostate stem cell antigen
chr12_+_118100977 1.325 NM_014365
HSPB8
heat shock 22kDa protein 8
chr1_+_199884152 1.321 NAV1
neuron navigator 1
chr17_-_45621312 1.309 COL1A1
collagen, type I, alpha 1
chr2_+_219354948 1.307 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr5_+_67558217 1.305 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_23376860 1.280 LUZP1
leucine zipper protein 1
chr5_+_140848905 1.260 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr2_-_110665188 1.255 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr1_+_221168388 1.251 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr8_-_37576515 1.244 LOC157860
hypothetical protein LOC157860
chr3_-_38666122 1.241 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr6_-_108252200 1.223 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr11_-_86060812 1.213 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr17_-_45619038 1.212 COL1A1
collagen, type I, alpha 1
chr1_+_165330710 1.208 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr11_+_1897374 1.183 NM_001042780
NM_001042781
NM_001042782
NM_006757
TNNT3



troponin T type 3 (skeletal, fast)



chr11_-_6298284 1.175 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr9_-_135334003 1.168 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr4_-_5881271 1.163 CRMP1
collapsin response mediator protein 1
chr17_+_45940911 1.144 MYCBPAP
MYCBP associated protein
chr2_-_161058550 1.137 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr11_+_61005160 1.135 NM_001170753
NM_145017
C11orf66

chromosome 11 open reading frame 66

chr1_+_17817397 1.134 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_+_59796858 1.117 NM_006863
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr12_+_50104859 1.102 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr1_+_200018380 1.095 NAV1
neuron navigator 1
chr17_-_36996611 1.092 NM_000526
KRT14
keratin 14
chr8_-_107851593 1.083 NM_139166
ABRA
actin-binding Rho activating protein
chr7_+_157339985 1.080 LOC100506585
hypothetical LOC100506585
chr11_-_1006736 1.048 MUC6
mucin 6, oligomeric mucus/gel-forming
chr5_+_72452131 1.041 NM_001161342
NM_173490
TMEM171

transmembrane protein 171

chr7_+_142459538 1.029 NM_001001667
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr2_-_128149112 1.028 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr16_-_65781499 1.024 NM_178516
EXOC3L1
exocyst complex component 3-like 1
chr12_-_47464143 1.020 NM_015270
ADCY6
adenylate cyclase 6
chr1_+_64983312 1.017 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr1_+_22176004 1.013 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr17_-_45621571 1.004 COL1A1
collagen, type I, alpha 1
chr7_+_116238309 0.999 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_149119029 0.995 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr22_-_16887151 0.985 NM_001122731
NM_001136004
NM_015241
MICAL3


microtubule associated monoxygenase, calponin and LIM domain containing 3


chr1_+_63832067 0.984 NM_001172819
PGM1
phosphoglucomutase 1
chr1_-_19998955 0.982 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr11_-_8788765 0.977 NM_213618
ST5
suppression of tumorigenicity 5
chr12_-_105056577 0.973 NUAK1
NUAK family, SNF1-like kinase, 1
chr3_-_46850588 0.971 NM_182702
PRSS42
protease, serine, 42
chr4_+_110991934 0.969 NM_198506
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr6_+_167658563 0.959 NM_031949
TTLL2
tubulin tyrosine ligase-like family, member 2
chr18_-_3870068 0.942 NM_004746
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr1_+_22200735 0.941 NM_005747
CELA3A
chymotrypsin-like elastase family, member 3A
chr6_+_36773605 0.937 RAB44
RAB44, member RAS oncogene family
chr1_+_18680010 0.931 NM_152375
KLHDC7A
kelch domain containing 7A
chr2_+_17861266 0.907 NM_001105569
MSGN1
mesogenin 1
chr19_+_53801811 0.906 NM_133498
SPACA4
sperm acrosome associated 4
chr7_-_27153892 0.905 NM_024014
HOXA6
homeobox A6
chr1_+_46413335 0.903 NM_005727
TSPAN1
tetraspanin 1
chr12_+_50592379 0.898 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr7_-_27186400 0.891 NM_153715
HOXA10
homeobox A10
chr5_+_145296313 0.891 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr8_-_124622434 0.878 NM_058229
FBXO32
F-box protein 32
chr4_+_77829634 0.876 SHROOM3
shroom family member 3
chr17_-_38421363 0.876 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr10_+_75427853 0.869 NM_003373
NM_014000
VCL

vinculin

chr16_-_47201588 0.869 NM_153029
N4BP1
NEDD4 binding protein 1
chr7_+_2409731 0.868 NM_018641
CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
chr8_-_20156971 0.859 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr11_+_122031549 0.850 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr20_-_49612574 0.847 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr14_+_92049396 0.846 NM_024832
RIN3
Ras and Rab interactor 3
chr1_+_156229686 0.840 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr15_+_71522551 0.840 NM_001042367
C15orf60
chromosome 15 open reading frame 60
chr15_-_73719546 0.834 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr4_-_152316105 0.833 NM_001128924
SH3D19
SH3 domain containing 19
chr3_+_16901455 0.831 NM_001144382
PLCL2
phospholipase C-like 2
chr9_+_115970599 0.826 COL27A1
collagen, type XXVII, alpha 1
chr1_+_2026014 0.821 NM_001033582
PRKCZ
protein kinase C, zeta
chrX_+_152608159 0.820 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr4_+_169989680 0.819 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr1_-_202726068 0.817 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr11_-_101906640 0.816 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr17_+_37122138 0.812 NM_000805
GAST
gastrin
chr20_-_49612745 0.810 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_-_169888373 0.804 NM_000261
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr22_+_21006814 0.804


chr7_-_21951946 0.799 NM_001127370
NM_001127371
NM_018719
CDCA7L


cell division cycle associated 7-like


chr7_-_139948780 0.798 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr5_+_159589014 0.798 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr22_+_29122932 0.795 NM_012429
NM_033382
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr12_-_121753795 0.785 NM_177551
GPR109A
G protein-coupled receptor 109A
chrX_+_47752113 0.783 NM_001079900
SPACA5
SPACA5B
sperm acrosome associated 5
sperm acrosome associated 5B
chr7_-_98643024 0.780 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr6_+_12622286 0.775


chr2_+_96790298 0.775 NM_020184
CNNM4
cyclin M4
chr11_+_60858611 0.771 DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr9_-_131555111 0.770 NM_004878
PTGES
prostaglandin E synthase
chr15_-_42274529 0.770 NM_032892
FRMD5
FERM domain containing 5
chr5_-_122400219 0.765 PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr2_+_33213111 0.764 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr19_-_51168396 0.760 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr11_-_123414917 0.760 NM_001004463
OR10G7
olfactory receptor, family 10, subfamily G, member 7
chr6_+_43846735 0.756 VEGFA
vascular endothelial growth factor A
chr22_-_35835548 0.754 TMPRSS6
transmembrane protease, serine 6
chr20_+_19818209 0.753 NM_018993
RIN2
Ras and Rab interactor 2
chr11_-_8789457 0.752 NM_139157
ST5
suppression of tumorigenicity 5
chr1_+_17738863 0.752 NM_018125
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr8_+_38877909 0.751 NM_021623
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr3_-_188936941 0.749 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr7_+_116099648 0.738 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr16_-_73798539 0.729 NM_001025200
CTRB1
CTRB2
chymotrypsinogen B1
chymotrypsinogen B2
chr1_+_63861474 0.728 NM_001172818
PGM1
phosphoglucomutase 1
chr15_-_81412354 0.727 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr9_+_132990760 0.727 NM_005085
NUP214
nucleoporin 214kDa
chr11_-_7941617 0.722 NM_176821
NLRP10
NLR family, pyrin domain containing 10
chr19_+_8814268 0.722 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr19_+_11211282 0.721 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr22_+_19651446 0.718 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr16_+_10878539 0.713 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr11_+_5925152 0.713 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr12_-_26169074 0.712 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr12_+_27511009 0.711 NM_001145010
C12orf70
chromosome 12 open reading frame 70
chr2_-_88208650 0.706 NM_001443
FABP1
fatty acid binding protein 1, liver
chr2_+_39000007 0.703 NM_001145451
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr1_+_204390905 0.702 NM_000707
AVPR1B
arginine vasopressin receptor 1B
chr20_-_42249146 0.698 JPH2
junctophilin 2
chr16_-_29781842 0.697 NM_006319
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr12_+_5473558 0.697 NM_002527
NTF3
neurotrophin 3
chr5_-_122400312 0.696 NM_000943
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr19_-_17217022 0.696 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr1_-_42978320 0.695 NM_001123395
NM_001185117
NM_148960
CLDN19


claudin 19


chr20_+_30061905 0.694 NM_080625
C20orf160
chromosome 20 open reading frame 160
chr3_-_42719322 0.692 NM_020707
HHATL
hedgehog acyltransferase-like
chr5_+_125828685 0.692 NM_001146322
GRAMD3
GRAM domain containing 3
chr6_-_26343139 0.692 NM_005320
HIST1H1D
histone cluster 1, H1d
chr1_+_156229934 0.687 KIRREL
kin of IRRE like (Drosophila)
chr3_-_3127057 0.687 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
IL5RA





interleukin 5 receptor, alpha





chr6_-_112147946 0.685 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr11_-_1007140 0.685 MUC6
mucin 6, oligomeric mucus/gel-forming
chr19_+_38867273 0.679 NM_022467
CHST8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr6_-_27222556 0.676 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr11_+_119586879 0.675 NM_178507
OAF
OAF homolog (Drosophila)
chr17_+_40580466 0.672 NM_006460
HEXIM1
hexamethylene bis-acetamide inducible 1
chr20_+_43764068 0.671 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr17_-_24972471 0.671 NM_032854
CORO6
coronin 6
chr18_+_606671 0.670 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr1_+_36160375 0.670 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr17_-_52248248 0.668 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr20_+_29492071 0.663 NM_153324
DEFB123
defensin, beta 123
chrX_+_100361588 0.663 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr20_-_42249631 0.661 NM_020433
NM_175913
JPH2

junctophilin 2

chr2_-_25418819 0.657 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_+_21249040 0.655 NM_001194958
KCNJ18
potassium inwardly-rectifying channel, subfamily J, member 18
chr7_+_48095464 0.655 UPP1
uridine phosphorylase 1
chr2_-_25418856 0.654 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr10_+_80942362 0.651 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr17_+_75625025 0.648 NM_017950
CCDC40
coiled-coil domain containing 40
chr19_-_14771947 0.647 NM_198944
OR7C1
olfactory receptor, family 7, subfamily C, member 1
chr9_+_132990834 0.647 NUP214
nucleoporin 214kDa
chr12_-_51360439 0.645 NM_006121
KRT1
keratin 1
chr20_+_34937928 0.642 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr14_+_23937766 0.641 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr1_-_180621272 0.641 GLUL
glutamate-ammonia ligase
chr5_-_38592439 0.636 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr1_+_117253882 0.635 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chrX_-_43717864 0.632 NM_000266
NDP
Norrie disease (pseudoglioma)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
9.87 4.90e-02 GO:0030055 cell-substrate junction

Nothing significant found in function category.