Motif ID: PBX1.p2

Z-value: 1.083


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1



Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_23008742 2.137 NGDN
neuroguidin, EIF4E binding protein
chr14_+_23008723 1.705 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr18_+_42780784 1.705 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr6_-_27222556 1.686 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr12_+_21570457 1.543 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr4_+_8935987 1.467 NM_001105662
USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr4_+_8940733 1.266 NM_001105662
USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr17_-_40594652 1.181


chr10_+_69539255 1.168 NM_032578
MYPN
myopalladin
chr5_+_90711887 1.135 LOC100129716
hypothetical LOC100129716
chr6_+_27222839 1.061 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr2_+_12774264 1.031 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr7_+_133982070 0.993 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr5_+_162797149 0.951 NM_004060
NM_199246
CCNG1

cyclin G1

chr8_-_12033677 0.946 NM_201402
USP17L2
ubiquitin specific peptidase 17-like 2
chr5_-_89741233 0.933 NM_004365
CETN3
centrin, EF-hand protein, 3
chr8_+_99145925 0.887 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr2_+_85676347 0.879 NM_016494
RNF181
ring finger protein 181
chr17_+_56109940 0.851 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr17_-_43977273 0.847 NM_002145
HOXB2
homeobox B2
chr6_+_26307691 0.841 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr6_+_160131472 0.840 NM_014161
MRPL18
mitochondrial ribosomal protein L18
chr17_+_43328514 0.837 NM_003110
SP2
Sp2 transcription factor
chr6_-_26343139 0.828 NM_005320
HIST1H1D
histone cluster 1, H1d
chr6_+_26232351 0.812 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr13_-_32757835 0.806 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr16_-_68346299 0.773 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr6_-_26232109 0.769 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr1_+_162795328 0.764 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr16_+_24459173 0.758 RBBP6
retinoblastoma binding protein 6
chr4_-_177950658 0.754 NM_005429
VEGFC
vascular endothelial growth factor C
chr15_+_39032927 0.754 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr7_-_135083906 0.750 NM_205855
FAM180A
family with sequence similarity 180, member A
chr3_+_173951163 0.734 ECT2
epithelial cell transforming sequence 2 oncogene
chr14_+_22860547 0.720 PABPN1
poly(A) binding protein, nuclear 1
chr16_-_3246587 0.718 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr5_+_139999182 0.717 NM_018502
TMCO6
transmembrane and coiled-coil domains 6
chr17_+_53670785 0.716 NM_001160102
NM_006151
LPO

lactoperoxidase

chr2_+_20510312 0.712 NM_004040
RHOB
ras homolog gene family, member B
chr1_+_16220952 0.712 NM_001042704
NM_004070
CLCNKA

CLCNKB
chloride channel Ka

chloride channel Kb
chr6_+_26212082 0.712 NM_003542
HIST1H4C
histone cluster 1, H4c
chr6_-_63053811 0.703 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr15_-_62460622 0.682 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr6_+_26153590 0.657 NM_003531
HIST1H3C
histone cluster 1, H3c
chr6_-_26307418 0.642 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr12_-_28016182 0.641 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr2_+_183651713 0.640 DUSP19
dual specificity phosphatase 19
chr2_+_44249565 0.627 PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr16_+_11346780 0.625 NM_152308
C16orf75
chromosome 16 open reading frame 75
chr6_+_111302679 0.618 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr13_+_94052022 0.600 NM_180989
GPR180
G protein-coupled receptor 180
chr14_+_23654161 0.596 DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_195336625 0.588 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr6_-_27943287 0.586 NM_005322
HIST1H1B
histone cluster 1, H1b
chr16_-_68880844 0.584 AARS
alanyl-tRNA synthetase
chr4_-_140696740 0.576 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr20_+_186376 0.575 NM_207469
DEFB132
defensin, beta 132
chr3_-_53139457 0.573 NM_052859
RFT1
RFT1 homolog (S. cerevisiae)
chr6_+_26381122 0.571 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr17_-_36074812 0.561 NM_152349
KRT222
keratin 222
chr17_-_43328141 0.559


chr16_-_68880908 0.557 NM_001605
AARS
alanyl-tRNA synthetase
chr14_+_22860511 0.555 PABPN1
poly(A) binding protein, nuclear 1
chr2_-_189752575 0.552 NM_000393
COL5A2
collagen, type V, alpha 2
chr3_+_195336631 0.550 HES1
hairy and enhancer of split 1, (Drosophila)
chr17_-_41794825 0.547 NM_001039083
NM_001103154
ARL17A
ARL17B

ADP-ribosylation factor-like 17A
ADP-ribosylation factor-like 17B

chr10_-_108448990 0.543 SORCS1
sortilin-related VPS10 domain containing receptor 1
chr12_-_56200547 0.541 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr1_-_152162074 0.539 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr2_-_183439515 0.534 NM_001463
FRZB
frizzled-related protein
chr20_-_54400628 0.533 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr20_+_18396030 0.528 NM_006466
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr2_+_62786290 0.519 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr20_+_29790564 0.519 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr15_+_39363442 0.516 LOC729082
hypothetical LOC729082
chr16_+_11346812 0.510 C16orf75
chromosome 16 open reading frame 75
chr14_-_22722680 0.505 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr9_+_91115924 0.501 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr2_-_211049619 0.499 NM_001136574
NM_006055
NM_001136575
LANCL1


LanC lantibiotic synthetase component C-like 1 (bacterial)


chr10_-_21847126 0.493


chr4_-_48477021 0.489 FRYL
FRY-like
chr2_+_183651531 0.489 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr17_+_43539909 0.485 NM_152244
NM_013323
SNX11

sorting nexin 11

chr22_-_37520049 0.483 DNAL4
dynein, axonemal, light chain 4
chr16_-_19440786 0.477 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr17_-_71174816 0.471 NM_004259
NM_001003715
NM_001003716
RECQL5


RecQ protein-like 5


chr6_-_169395847 0.469 THBS2
thrombospondin 2
chr15_+_41597097 0.466 NM_002373
MAP1A
microtubule-associated protein 1A
chr12_+_21059896 0.466 NM_001009562
LST-3TM12
organic anion transporter LST-3b
chr10_-_44794146 0.466 NM_007021
C10orf10
chromosome 10 open reading frame 10
chrX_+_110252960 0.464 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr12_+_27568311 0.463 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr1_+_13948518 0.460 PRDM2
PR domain containing 2, with ZNF domain
chr10_+_124310170 0.451 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr10_+_63331401 0.450 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_-_26358811 0.449 NM_021018
HIST1H3F
histone cluster 1, H3f
chr14_-_68329407 0.444 NM_004926
ZFP36L1
zinc finger protein 36, C3H type-like 1
chr2_-_154043403 0.444 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr14_+_73621408 0.442 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr7_+_106596641 0.437 NM_012257
HBP1
HMG-box transcription factor 1
chr6_+_160103500 0.436 ACAT2
acetyl-CoA acetyltransferase 2
chr12_-_51233001 0.433 NM_033448
KRT71
keratin 71
chr17_-_42012324 0.432 NM_001113738
NM_016632
NM_001039083
ARL17A

ARL17B
ADP-ribosylation factor-like 17A

ADP-ribosylation factor-like 17B
chr1_+_109036431 0.426 NM_018061
PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr3_-_150422474 0.425 NM_000096
CP
ceruloplasmin (ferroxidase)
chr6_-_32892705 0.422 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr6_-_166960649 0.415 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_183651756 0.412 DUSP19
dual specificity phosphatase 19
chr17_+_43540124 0.406 SNX11
sorting nexin 11
chr3_-_46993225 0.401 NM_144716
CCDC12
coiled-coil domain containing 12
chr1_+_13948448 0.394 NM_001007257
PRDM2
PR domain containing 2, with ZNF domain
chr11_+_95163457 0.391 CEP57
centrosomal protein 57kDa
chr1_+_13948504 0.390 PRDM2
PR domain containing 2, with ZNF domain
chr5_+_176494690 0.379 NSD1
nuclear receptor binding SET domain protein 1
chr22_-_37520092 0.376 NM_005740
DNAL4
dynein, axonemal, light chain 4
chr15_-_35178888 0.370 NM_172316
MEIS2
Meis homeobox 2
chr17_+_71174993 0.370 NM_013260
SAP30BP
SAP30 binding protein
chr15_-_35179185 0.369 MEIS2
Meis homeobox 2
chr2_+_218843358 0.369 NM_001077399
NM_015488
PNKD

paroxysmal nonkinesigenic dyskinesia

chr20_-_13567529 0.361 NM_017714
TASP1
taspase, threonine aspartase, 1
chr18_+_45342398 0.360 NM_006033
LIPG
lipase, endothelial
chr14_+_64041257 0.358 ZBTB1
zinc finger and BTB domain containing 1
chr7_-_30510849 0.357 NM_024051
GGCT
gamma-glutamylcyclotransferase
chr10_-_115923874 0.356 C10orf118
chromosome 10 open reading frame 118
chr6_-_25679197 0.353


chr16_+_18986721 0.353 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_46728188 0.352 NM_016593
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr3_+_157343444 0.348 NM_003471
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr10_-_101180191 0.347 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr21_-_33935883 0.345 NM_145858
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr12_+_49728350 0.342 NM_001024668
NM_015416
LETMD1

LETM1 domain containing 1

chr16_+_18986459 0.340 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr14_-_23653965 0.337 NRL
neural retina leucine zipper
chr1_-_13546097 0.337 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chr12_-_54150188 0.335 NM_001005499
OR6C70
olfactory receptor, family 6, subfamily C, member 70
chr7_-_526005 0.334 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr14_-_35859545 0.333 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr2_-_88208650 0.332 NM_001443
FABP1
fatty acid binding protein 1, liver
chr16_-_15889947 0.325 NM_144600
C16orf63
chromosome 16 open reading frame 63
chr4_-_48477038 0.321 NM_015030
FRYL
FRY-like
chr5_-_171814026 0.318 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr16_+_18986417 0.318 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr22_+_38903825 0.316 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr4_-_118226119 0.315 NM_152402
TRAM1L1
translocation associated membrane protein 1-like 1
chr14_-_22722658 0.314 SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr1_-_17638797 0.314 NM_018715
RCC2
regulator of chromosome condensation 2
chr1_-_42574116 0.312 NM_001198850
FOXJ3
forkhead box J3
chr7_-_121571472 0.305 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr20_+_18436525 0.303 SEC23B
Sec23 homolog B (S. cerevisiae)
chr2_+_27109341 0.298 TMEM214
transmembrane protein 214
chr6_+_135544170 0.298 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr12_+_63090008 0.297 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr17_-_71023221 0.297 NM_020753
CASKIN2
CASK interacting protein 2
chr6_-_166960690 0.295 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_-_108579270 0.294 NM_001146
ANGPT1
angiopoietin 1
chr11_+_61647990 0.293 NM_001040694
NM_020238
INCENP

inner centromere protein antigens 135/155kDa

chr3_-_71196696 0.293 FOXP1
forkhead box P1
chr2_-_88707978 0.293 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr18_+_12981329 0.290 NM_032142
CEP192
centrosomal protein 192kDa
chr14_-_105804211 0.286 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_76133206 0.286 NM_001163034
NM_020761
RPTOR

regulatory associated protein of MTOR, complex 1

chr17_-_36456949 0.285 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr11_-_85074848 0.281 NM_152723
CCDC89
coiled-coil domain containing 89
chr2_-_97646758 0.279 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr6_+_83834080 0.279 NM_015018
DOPEY1
dopey family member 1
chr15_+_91244563 0.274 CHD2
chromodomain helicase DNA binding protein 2
chr17_+_38576707 0.274 NM_005899
NBR1
neighbor of BRCA1 gene 1
chr16_-_778375 0.273 NM_058192
RPUSD1
RNA pseudouridylate synthase domain containing 1
chr14_+_51025604 0.272 NM_001042481
FRMD6
FERM domain containing 6
chr13_+_96726415 0.272 MBNL2
muscleblind-like 2 (Drosophila)
chr6_-_166960496 0.269 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_239749634 0.269 FH
fumarate hydratase
chr17_+_20970828 0.268 NM_015510
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr12_+_64982542 0.268 NM_033647
HELB
helicase (DNA) B
chr17_-_71023048 0.267 CASKIN2
CASK interacting protein 2
chr5_-_171813960 0.267 SH3PXD2B
SH3 and PX domains 2B
chr12_+_52689062 0.266 NM_022658
HOXC8
homeobox C8
chr16_-_74024750 0.265 NM_006324
CFDP1
craniofacial development protein 1
chr6_+_126143971 0.263 NCOA7
nuclear receptor coactivator 7
chr16_+_81218074 0.262 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr20_-_5879036 0.258 NM_015939
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr1_+_25629968 0.258 NM_018202
TMEM57
transmembrane protein 57
chr3_+_112934016 0.256 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr17_-_39333490 0.255 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr16_+_2593351 0.255 LOC652276
hypothetical LOC652276
chr6_+_26473376 0.255 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr2_+_191453792 0.254 GLS
glutaminase
chr14_-_21172837 0.252 NM_001005466
OR10G2
olfactory receptor, family 10, subfamily G, member 2
chr10_+_96512447 0.251 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr15_+_91244422 0.251 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr12_-_118799457 0.250 NM_007174
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr4_-_111339201 0.250 NM_001130721
NM_024090
ELOVL6

ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)

chr1_-_17638729 0.249 RCC2
regulator of chromosome condensation 2
chr2_+_191453791 0.249 NM_014905
GLS
glutaminase
chr6_+_151603201 0.245 AKAP12
A kinase (PRKA) anchor protein 12
chr20_+_18436548 0.244 NM_001172745
SEC23B
Sec23 homolog B (S. cerevisiae)
chr11_-_61823078 0.243 NM_206998
SCGB1D4
secretoglobin, family 1D, member 4
chr2_+_27109249 0.242 NM_001083590
NM_017727
TMEM214

transmembrane protein 214

chr2_+_191453813 0.241 GLS
glutaminase
chr1_+_234624266 0.232 NM_145861
EDARADD
EDAR-associated death domain

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
55.02 1.03e-02 GO:0000786 nucleosome
2.72 1.14e-02 GO:0005634 nucleus
4.10 1.45e-02 GO:0043228 non-membrane-bounded organelle
4.10 1.45e-02 GO:0043232 intracellular non-membrane-bounded organelle
35.20 2.51e-02 GO:0032993 protein-DNA complex

Nothing significant found in function category.