Motif ID: PDX1.p2

Z-value: 0.629


Transcription factors associated with PDX1.p2:

Gene SymbolEntrez IDGene Name
PDX1 3651 pancreatic and duodenal homeobox 1



Activity profile for motif PDX1.p2.

activity profile for motif PDX1.p2


Sorted Z-values histogram for motif PDX1.p2

Sorted Z-values for motif PDX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_21767819 0.804 NM_024697
ZNF385D
zinc finger protein 385D
chr2_+_113452066 0.729 NM_019618
IL1F9
interleukin 1 family, member 9
chr8_-_17624304 0.716 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr21_+_44844924 0.692 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr11_-_123182266 0.638 NM_001005325
OR6M1
olfactory receptor, family 6, subfamily M, member 1
chr22_-_16070778 0.621 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr1_+_40635058 0.618 NM_001198980
SMAP2
small ArfGAP2
chr10_+_63478974 0.586 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_-_20122638 0.524 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr3_+_46594079 0.513 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr8_-_17624009 0.494 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr7_+_147918589 0.492 NM_145304
C7orf33
chromosome 7 open reading frame 33
chr6_-_133076873 0.466 NM_004666
VNN1
vanin 1
chr7_-_92615593 0.421 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr7_+_142459538 0.407 NM_001001667
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr3_-_139315011 0.378 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr1_+_184532027 0.371 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr4_+_109033868 0.366 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr1_+_62835759 0.366 NM_014495
ANGPTL3
angiopoietin-like 3
chr17_-_36890877 0.334 NM_002280
KRT35
keratin 35
chr7_+_116182676 0.315


chr10_-_62002672 0.314 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr15_-_38185578 0.281 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr4_-_176970372 0.277 GPM6A
glycoprotein M6A
chr7_-_44195405 0.273 NM_000162
GCK
glucokinase (hexokinase 4)
chr17_+_7900926 0.265


chr9_+_140226457 0.263 NM_001145249
FAM157B
family with sequence similarity 157, member B
chr17_-_36409632 0.263 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr16_-_3025542 0.262 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr1_+_157246305 0.260 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr19_-_57100052 0.258 NM_023074
ZNF649
zinc finger protein 649
chr2_+_17861266 0.258 NM_001105569
MSGN1
mesogenin 1
chr4_-_176970407 0.252 GPM6A
glycoprotein M6A
chr17_-_36725470 0.251 NM_031964
KRTAP17-1
keratin associated protein 17-1
chr6_-_55848346 0.241 BMP5
bone morphogenetic protein 5
chr1_-_33613729 0.240 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr21_-_44824907 0.236 NM_198694
KRTAP10-5
keratin associated protein 10-5
chr5_-_180099663 0.230 NM_001001657
OR2Y1
olfactory receptor, family 2, subfamily Y, member 1
chr19_-_7672978 0.225 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr3_+_199363633 0.211 NM_001145248
FAM157A
family with sequence similarity 157, member A
chr9_+_124416768 0.206 NM_012364
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr3_+_185253528 0.202 NM_130770
HTR3C
5-hydroxytryptamine (serotonin) receptor 3, family member C
chr21_-_45173061 0.201 NM_001127491
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr8_-_81155564 0.178 NM_001025252
TPD52
tumor protein D52
chr18_-_45630154 0.176 MYO5B
myosin VB
chr1_+_43508251 0.172 NM_144626
TMEM125
transmembrane protein 125
chr17_-_36418869 0.170 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr18_+_606671 0.167 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr8_+_26569709 0.160 DPYSL2
dihydropyrimidinase-like 2
chr8_+_76614757 0.160 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr11_-_4893468 0.158 NM_001005238
OR51G2
olfactory receptor, family 51, subfamily G, member 2
chr11_-_4924905 0.152 NM_001005329
OR51A4
olfactory receptor, family 51, subfamily A, member 4
chr17_-_36113502 0.149 NM_019016
KRT24
keratin 24
chr9_+_33614214 0.148 ANXA2P2
annexin A2 pseudogene 2
chr12_+_4569504 0.145 NM_003845
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr10_+_118177371 0.144 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr5_-_134290789 0.142


chr6_+_167624792 0.130 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr11_+_61732715 0.127 NM_002407
SCGB2A1
secretoglobin, family 2A, member 1
chr6_+_147566559 0.126 STXBP5
syntaxin binding protein 5 (tomosyn)
chr2_+_169629544 0.121 NM_005771
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr10_+_80942362 0.120 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr7_+_129057152 0.118 NM_001040110
NRF1
nuclear respiratory factor 1
chr7_-_128330615 0.117 KCP
kielin/chordin-like protein
chr12_+_31691360 0.115 NM_001135864
METTL20
methyltransferase like 20
chr7_+_128099581 0.113 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr16_-_21078262 0.112 NM_017539
DNAH3
dynein, axonemal, heavy chain 3
chr4_-_170314382 0.111 SH3RF1
SH3 domain containing ring finger 1
chr1_+_69998445 0.109 NM_020794
LRRC7
leucine rich repeat containing 7
chr17_-_39499527 0.104 LSM12
LSM12 homolog (S. cerevisiae)
chr3_-_145049853 0.103 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr3_+_44992733 0.102 NM_015004
EXOSC7
exosome component 7
chr5_+_34720368 0.101 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr5_-_172016174 0.099


chr4_+_77575276 0.096 NM_020859
SHROOM3
shroom family member 3
chr8_-_17599438 0.094 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr12_+_118100977 0.094 NM_014365
HSPB8
heat shock 22kDa protein 8
chr4_+_86615275 0.094 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr21_-_30460841 0.091 NM_012131
CLDN17
claudin 17
chr2_-_158008763 0.091 NM_004288
CYTIP
cytohesin 1 interacting protein
chr9_+_135491305 0.090 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr6_+_144654565 0.089 NM_007124
UTRN
utrophin
chr6_-_32227695 0.088 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr2_-_199922047 0.086 SATB2
SATB homeobox 2
chr17_-_36403910 0.086 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr1_-_202402043 0.086 NM_000537
REN
renin
chr5_+_140698537 0.086 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chr6_+_160247962 0.085 NM_002377
MAS1
MAS1 oncogene
chr6_-_32227645 0.084 PRRT1
proline-rich transmembrane protein 1
chr6_-_55848317 0.084 NM_021073
BMP5
bone morphogenetic protein 5
chr8_+_32698892 0.082 NM_001159996
NRG1
neuregulin 1
chr3_-_44992604 0.079 NM_001135179
NM_016598
ZDHHC3

zinc finger, DHHC-type containing 3

chr1_+_36409277 0.079 MAP7D1
MAP7 domain containing 1
chr7_+_104468614 0.077 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_+_151456683 0.076 NM_001195571
PRR9
proline rich 9
chr1_-_150328153 0.074 NM_001008536
TCHHL1
trichohyalin-like 1
chr12_-_119938593 0.074 C12orf43
chromosome 12 open reading frame 43
chr12_-_119938667 0.074 NM_022895
C12orf43
chromosome 12 open reading frame 43
chr19_-_40711034 0.074 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr14_+_20580224 0.069 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr17_+_32807040 0.068 NM_173625
C17orf78
chromosome 17 open reading frame 78
chr4_+_74825138 0.068 NM_000584
IL8
interleukin 8
chr1_-_161379606 0.068 RGS5
regulator of G-protein signaling 5
chr16_-_66075216 0.067 NM_001138
AGRP
agouti related protein homolog (mouse)
chr7_+_156128431 0.066 NM_001184997
RNF32
ring finger protein 32
chr8_-_27906287 0.066 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr1_-_230717850 0.065 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr11_-_5130174 0.062 NM_012375
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr17_-_36444626 0.059 NM_030966
KRTAP1-3
keratin associated protein 1-3
chr2_-_121964373 0.057 CLASP1
cytoplasmic linker associated protein 1
chr10_+_70650064 0.057 NM_025130
HKDC1
hexokinase domain containing 1
chr17_-_39500512 0.056 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chr3_-_47909001 0.055 MAP4
microtubule-associated protein 4
chr7_+_93373755 0.055 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr6_-_138581319 0.052 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr22_-_23665312 0.051 NM_001001663
TMEM211
transmembrane protein 211
chr11_+_6823458 0.048 NM_178168
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr6_-_131333173 0.048 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr12_+_74071145 0.047 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr2_+_105799354 0.047 NCK2
NCK adaptor protein 2
chr6_-_41362370 0.047 NM_018643
TREM1
triggering receptor expressed on myeloid cells 1
chr3_-_152517204 0.047 NM_023915
GPR87
G protein-coupled receptor 87
chr3_+_11153778 0.045 NM_001098213
HRH1
histamine receptor H1
chr12_+_10351683 0.044 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr11_-_57883117 0.044 NM_001005489
OR5B17
olfactory receptor, family 5, subfamily B, member 17
chr19_-_14646626 0.044 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr17_-_45629401 0.043


chr10_+_90474280 0.041 NM_001080518
LIPK
lipase, family member K
chr15_-_42756377 0.041 NM_001145112
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr6_+_158653679 0.040 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr4_+_71492581 0.040 NM_016519
AMBN
ameloblastin (enamel matrix protein)
chr4_+_53975597 0.038 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr7_+_143423073 0.036 NM_001004135
OR2A12
olfactory receptor, family 2, subfamily A, member 12
chr3_+_35658852 0.035 NM_016300
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_141879555 0.035 NM_152616
TRIM42
tripartite motif containing 42
chr4_+_187424111 0.035 NM_000128
F11
coagulation factor XI
chr17_-_39499463 0.034 LSM12
LSM12 homolog (S. cerevisiae)
chr14_-_76958984 0.033 NM_138791
NM_001113475
C14orf148

chromosome 14 open reading frame 148

chr12_-_102968044 0.033 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr5_+_147628567 0.033 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr3_+_52786642 0.033 NM_002215
ITIH1
inter-alpha (globulin) inhibitor H1
chr5_+_179934143 0.033 CNOT6
CCR4-NOT transcription complex, subunit 6
chr1_+_78858675 0.032 NM_006820
IFI44L
interferon-induced protein 44-like
chr15_-_38185865 0.031 NM_033503
BMF
Bcl2 modifying factor
chr21_-_30631882 0.030 NM_001077711
KRTAP27-1
keratin associated protein 27-1
chr7_+_120752656 0.029 NM_016087
WNT16
wingless-type MMTV integration site family, member 16
chr6_-_46933901 0.028 GPR116
G protein-coupled receptor 116
chr5_-_142795269 0.028 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr14_-_46882144 0.027 NM_182830
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr8_+_92330691 0.027 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr17_+_35372751 0.026 NM_178171
GSDMA
gasdermin A
chr12_+_103677388 0.026 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr3_-_69120188 0.024 C3orf64
chromosome 3 open reading frame 64
chr11_+_123945102 0.024 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr4_-_176970895 0.023 GPM6A
glycoprotein M6A
chr6_-_52060327 0.022 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chrX_+_123062143 0.021 STAG2
stromal antigen 2
chr18_+_27152049 0.020 NM_001942
DSG1
desmoglein 1
chr12_+_74071116 0.019 GLIPR1L2
GLI pathogenesis-related 1 like 2
chrX_+_118592568 0.019 UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr4_+_89115825 0.019 NM_000582
NM_001040058
NM_001040060
SPP1


secreted phosphoprotein 1


chr2_-_99412694 0.017 REV1
REV1 homolog (S. cerevisiae)
chrX_+_118592879 0.017 UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr18_+_59374372 0.017 NM_080474
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr12_+_4700012 0.016 NM_017417
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr1_+_161305558 0.016 NM_001113381
RGS4
regulator of G-protein signaling 4
chr4_-_24590867 0.015 NM_173463
CCDC149
coiled-coil domain containing 149
chr2_+_169634330 0.015 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr11_-_70971556 0.013 NM_001005405
KRTAP5-11
keratin associated protein 5-11
chr17_-_36559579 0.013 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr2_-_27215781 0.012 NM_178553
C2orf53
chromosome 2 open reading frame 53
chr6_-_29563657 0.011 NM_052967
MAS1L
MAS1 oncogene-like
chr11_+_55162409 0.011 NM_001004124
OR4P4
olfactory receptor, family 4, subfamily P, member 4
chr3_+_99350859 0.009 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr16_+_29582480 0.009 SPN
sialophorin
chr12_+_108061584 0.008 NM_001093
ACACB
acetyl-CoA carboxylase beta
chr9_+_96561750 0.008 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr12_+_21417068 0.007 NM_000415
IAPP
islet amyloid polypeptide
chr5_-_119768430 0.006


chr10_+_126620681 0.006 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr10_+_86174665 0.006 FAM190B
family with sequence similarity 190, member B
chr18_+_19286784 0.006 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr1_+_28637247 0.005 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr3_-_115826481 0.005 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_110155237 0.005 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr1_-_245942679 0.005 NM_001005286
OR6F1
olfactory receptor, family 6, subfamily F, member 1
chr2_+_204440753 0.004 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr1_-_153915867 0.003


chr2_+_24660849 0.003 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr12_-_54150188 0.003 NM_001005499
OR6C70
olfactory receptor, family 6, subfamily C, member 70
chr9_+_81377419 0.002 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr4_-_69116839 0.002 NM_001077
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr12_-_14740694 0.002 NM_004963
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr2_+_203763649 0.002 RPL12
ribosomal protein L12
chr13_-_109236897 0.001 NM_003749
IRS2
insulin receptor substrate 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.