Motif ID: POU2F1..3.p2

Z-value: 0.957


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3



Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_26232351 1.464 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr6_-_33016561 1.202 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr22_+_21407066 1.046


chr22_+_21370394 1.002 IGL@
immunoglobulin lambda locus
chr6_-_26232109 0.945 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr6_+_26325124 0.911 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr6_+_26359805 0.897 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr1_-_153098811 0.883 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_-_10523203 0.858 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr22_+_21495273 0.847


chr6_+_26266311 0.808 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr17_+_60563963 0.784 RGS9
regulator of G-protein signaling 9
chr17_+_19999784 0.780 NM_001033554
NM_001033555
SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr6_-_10523424 0.778 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_27222556 0.752 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr6_-_168222645 0.750 NM_024919
FRMD1
FERM domain containing 1
chr14_+_22422270 0.700 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr22_+_21094094 0.690


chr16_-_73365975 0.681 FA2H
fatty acid 2-hydroxylase
chr1_+_154386358 0.664 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr22_+_21116283 0.664


chr11_-_11331411 0.662 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr22_+_31080871 0.659 NM_006604
RFPL3
ret finger protein-like 3
chr5_+_2805261 0.655 NM_178569
C5orf38
chromosome 5 open reading frame 38
chr16_+_84202515 0.646 NM_001134473
KIAA0182
KIAA0182
chr6_-_26324850 0.644 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr22_+_20899155 0.638


chr6_-_89984214 0.635 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr6_+_155579788 0.632 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr22_+_20316968 0.630 NM_152612
CCDC116
coiled-coil domain containing 116
chr1_+_202000906 0.602 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr6_+_27208763 0.596 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr2_+_96790298 0.596 NM_020184
CNNM4
cyclin M4
chr16_-_73366200 0.582 NM_024306
FA2H
fatty acid 2-hydroxylase
chr22_+_21340757 0.581


chr15_+_76171981 0.581 NM_001101404
SH2D7
SH2 domain containing 7
chr6_-_143307976 0.581 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr22_+_21042091 0.575 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr10_-_98021144 0.572 NM_001114094
NM_013314
BLNK

B-cell linker

chr17_+_60563917 0.571 NM_001081955
NM_001165933
NM_003835
RGS9


regulator of G-protein signaling 9


chr19_+_45996881 0.569 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr12_+_91620749 0.544 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr5_-_73972055 0.539 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr4_-_40212670 0.533 NM_019027
RBM47
RNA binding motif protein 47
chr21_+_38566298 0.515 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_+_25834983 0.514 NM_170610
HIST1H2BA
histone cluster 1, H2ba
chr22_+_21384862 0.503 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr17_-_45427565 0.501 NM_005220
DLX3
distal-less homeobox 3
chr6_-_53121540 0.496 NM_003643
GCM1
glial cells missing homolog 1 (Drosophila)
chr5_-_2804768 0.496 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr19_+_45996940 0.493 EGLN2
egl nine homolog 2 (C. elegans)
chr6_-_27208507 0.490 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr16_+_23754822 0.488 PRKCB
protein kinase C, beta
chr14_-_105862080 0.486 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr3_+_153074118 0.481 NM_033050
SUCNR1
succinate receptor 1
chr1_+_204797079 0.477 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr4_-_186970366 0.475 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr6_+_20510019 0.464 NM_001949
E2F3
E2F transcription factor 3
chr19_-_48815853 0.462 NM_182498
ZNF428
zinc finger protein 428
chr16_+_23754860 0.459 PRKCB
protein kinase C, beta
chr6_-_56515640 0.458


chr6_+_26291936 0.455 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr22_+_20715340 0.452


chr1_+_165564904 0.446 NM_001198783
POU2F1
POU class 2 homeobox 1
chr14_-_23623657 0.439 NM_006177
NRL
neural retina leucine zipper
chr22_+_21006814 0.437


chr5_+_36644187 0.435 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr20_-_48980858 0.434 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr3_+_114733907 0.434 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr1_-_42738535 0.428 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr12_+_14409875 0.420 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr16_+_23754997 0.418 PRKCB
protein kinase C, beta
chr9_-_126573349 0.412 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr22_+_20880159 0.406 IGLV6-57
immunoglobulin lambda variable 6-57
chr13_-_35327798 0.405 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr6_+_34312906 0.403 HMGA1
high mobility group AT-hook 1
chr6_-_170442090 0.401


chr6_+_37245860 0.394 NM_002648
PIM1
pim-1 oncogene
chr22_+_20880112 0.394


chr12_-_54646061 0.392 NM_006928
PMEL
premelanosome protein
chr6_+_34312667 0.392 HMGA1
high mobility group AT-hook 1
chr1_+_165565006 0.390 POU2F1
POU class 2 homeobox 1
chr6_-_25834733 0.386 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr8_+_56954953 0.383 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_-_11887265 0.382 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr1_-_2447848 0.380 NM_018216
PANK4
pantothenate kinase 4
chr6_-_26141774 0.377 NM_003513
HIST1H2AB
histone cluster 1, H2ab
chr7_+_111908143 0.370 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr17_-_53849929 0.370 NM_017763
RNF43
ring finger protein 43
chr14_-_19252330 0.367 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr21_+_29322100 0.364 USP16
ubiquitin specific peptidase 16
chr3_+_122794859 0.362 NM_016298
FBXO40
F-box protein 40
chr16_+_23754772 0.355 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr15_+_78520634 0.349 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr17_+_54997667 0.348 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr2_-_113310796 0.346 NM_000576
IL1B
interleukin 1, beta
chr19_+_40541327 0.345 NM_005304
FFAR3
free fatty acid receptor 3
chr1_+_204797120 0.345 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr7_-_112515068 0.341 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr3_+_99733432 0.341 NM_005290
GPR15
G protein-coupled receptor 15
chr6_+_27969181 0.341 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr20_+_32755778 0.339 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr10_+_106103503 0.335 NM_001008723
CCDC147
coiled-coil domain containing 147
chr16_-_87280380 0.326 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr16_-_57309625 0.323 GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr7_-_112514990 0.320 GPR85
G protein-coupled receptor 85
chr6_+_27222839 0.318 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr17_-_53849888 0.314 RNF43
ring finger protein 43
chr22_+_21543671 0.312 IGLV4-3
immunoglobulin lambda variable 4-3
chr6_+_34313007 0.302 HMGA1
high mobility group AT-hook 1
chr1_+_32311084 0.301 NM_018056
TMEM39B
transmembrane protein 39B
chr10_-_62002672 0.300 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_32311108 0.300 TMEM39B
transmembrane protein 39B
chr6_+_53043729 0.297 NM_012347
FBXO9
F-box protein 9
chr3_+_187917791 0.293 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr11_-_34336102 0.293 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr6_+_139136349 0.293 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr2_-_206790871 0.292 NM_001098199
NM_005279
GPR1

G protein-coupled receptor 1

chr17_-_34575939 0.289 NM_001143968
ARL5C
ADP-ribosylation factor-like 5C
chr6_-_128263868 0.288 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr22_+_21065134 0.287 LOC100290481
immunoglobulin lambda light chain-like
chr17_-_16816113 0.282 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr17_+_24394281 0.281 PIPOX
pipecolic acid oxidase
chr6_+_34312979 0.279 HMGA1
high mobility group AT-hook 1
chr16_-_87280289 0.274 SNAI3
snail homolog 3 (Drosophila)
chr7_-_112515035 0.273 GPR85
G protein-coupled receptor 85
chr8_+_56954946 0.268 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr14_-_105644300 0.266 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr5_+_73145098 0.265 RGNEF
190 kDa guanine nucleotide exchange factor
chr1_+_200246370 0.265 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr2_-_172458970 0.264 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr5_-_66528330 0.259 NM_005582
CD180
CD180 molecule
chr9_+_128716867 0.258 NM_001190729
NM_001190730
NM_014636
RALGPS1


Ral GEF with PH domain and SH3 binding motif 1


chr1_-_6537139 0.257 NOL9
nucleolar protein 9
chr12_-_47250069 0.256 NM_002289
LALBA
lactalbumin, alpha-
chr1_+_200246312 0.256 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr22_+_21065202 0.254


chr6_+_21701942 0.254 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr8_+_56954899 0.254 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr22_+_21065207 0.253 IGLJ3
immunoglobulin lambda joining 3
chr5_-_16561936 0.253 NM_019000
FAM134B
family with sequence similarity 134, member B
chr19_+_14554895 0.246 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr12_+_52653176 0.246 NM_014212
HOXC11
homeobox C11
chr20_+_62266217 0.242 MYT1
myelin transcription factor 1
chr8_+_123863169 0.240 ZHX2
zinc fingers and homeoboxes 2
chr7_-_102576570 0.239 NM_001122838
NM_198990
NAPEPLD

N-acyl phosphatidylethanolamine phospholipase D

chr11_-_62115545 0.238 NM_022830
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr20_-_60415729 0.234 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr12_-_31370387 0.233 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr7_-_27206249 0.233 NM_000522
HOXA13
homeobox A13
chr2_+_54638957 0.230 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr14_-_33489708 0.224 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr9_-_94226380 0.222 NM_005014
OMD
osteomodulin
chr20_-_39680405 0.219 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr17_-_38529638 0.218 NM_007298
BRCA1
breast cancer 1, early onset
chr7_+_100021862 0.218 NM_033506
FBXO24
F-box protein 24
chr3_-_52688768 0.218 NM_018165
NM_181042
PBRM1

polybromo 1

chr4_-_91979113 0.216 NM_183049
TMSL3
thymosin-like 3
chr10_-_64246129 0.215 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr5_-_64813459 0.214 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr12_-_11066436 0.213 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr9_+_108726257 0.213 ZNF462
zinc finger protein 462
chr15_+_65245546 0.213 NM_001145104
SMAD3
SMAD family member 3
chr14_-_67353046 0.212 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr19_-_45253947 0.212 NM_001005851
ZNF780B
zinc finger protein 780B
chr6_-_26151863 0.211 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr6_+_41118214 0.210 NM_001010873
NM_001159726
TSPO2

translocator protein 2

chr19_-_18253413 0.208 NM_005354
JUND
jun D proto-oncogene
chr1_+_201711505 0.208 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr2_-_175170674 0.207 WIPF1
WAS/WASL interacting protein family, member 1
chr16_+_10878539 0.206 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr3_-_48569213 0.205 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr22_-_22426551 0.204 NM_013378
VPREB3
pre-B lymphocyte 3
chr1_-_6537171 0.204 NM_024654
NOL9
nucleolar protein 9
chr6_-_11340887 0.201 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr1_-_181889070 0.200 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr12_-_55730125 0.199 NM_005379
MYO1A
myosin IA
chr17_-_44249379 0.198 NM_001130918
TTLL6
tubulin tyrosine ligase-like family, member 6
chr5_-_142045770 0.198 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr10_-_64246080 0.196 EGR2
early growth response 2
chr5_+_140730014 0.196 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr14_+_18447521 0.195 NM_001013354
OR11H12
olfactory receptor, family 11, subfamily H, member 12
chr6_-_11340886 0.194 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr1_-_148050534 0.192 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr17_-_30783631 0.192 NM_018042
SLFN12
schlafen family member 12
chr6_-_11340869 0.189 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr6_-_99904251 0.189 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr17_-_59363352 0.189 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr18_-_45271938 0.189 RPL17-C18ORF32
RPL17
RPL17-C18orf32 read-through transcript
ribosomal protein L17
chr22_-_41340781 0.188 POLDIP3
polymerase (DNA-directed), delta interacting protein 3
chr6_-_170441493 0.188 NM_005618
DLL1
delta-like 1 (Drosophila)
chr9_-_32516164 0.187 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr12_-_55614311 0.186 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr6_+_34312641 0.186 HMGA1
high mobility group AT-hook 1
chr22_-_41340886 0.186 NM_032311
NM_178136
POLDIP3

polymerase (DNA-directed), delta interacting protein 3

chr7_+_50318801 0.184 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr5_-_111119846 0.183 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr7_+_90176647 0.182 NM_012395
CDK14
cyclin-dependent kinase 14
chr2_-_152393209 0.180 NM_001037174
NM_012097
NM_177985
ARL5A


ADP-ribosylation factor-like 5A


chr12_-_120725210 0.179 LOC338799
hypothetical LOC338799

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.