Motif ID: RREB1.p2

Z-value: 6.512


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1



Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_17665483 13.433 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr16_-_3225360 12.578 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr19_-_55914837 11.479


chr4_-_809879 10.811 NM_006651
CPLX1
complexin 1
chr20_+_55359551 10.456 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr3_+_187917791 10.069 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr20_+_55359706 9.929 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr21_+_42946719 9.555 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr16_-_3225070 9.264 NM_001145447
NM_003454
ZNF200

zinc finger protein 200

chr19_-_51168396 8.642 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr7_+_44110527 7.867 AEBP1
AE binding protein 1
chr11_-_133786935 7.729 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr7_+_44110470 7.708 NM_001129
AEBP1
AE binding protein 1
chr4_-_46086528 7.474 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_-_202647526 7.158 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr16_+_86193993 7.002 NM_020655
JPH3
junctophilin 3
chr19_+_3317589 6.886 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_48966394 6.858 TRABD
TraB domain containing
chr22_+_48966480 6.731 NM_025204
TRABD
TraB domain containing
chr4_+_191235959 6.705 NM_001177376
DUX4L4
double homeobox 4 like 4
chr5_+_78943998 6.685 NM_001114393
NM_001114394
NM_173797
PAPD4


PAP associated domain containing 4


chr17_+_77582774 6.469 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr5_+_78944052 6.162 PAPD4
PAP associated domain containing 4
chr3_+_12304332 6.097 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr12_+_6807831 5.948 NM_014262
LEPREL2
leprecan-like 2
chr19_+_540849 5.724 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_+_42128521 5.655 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr5_+_78944151 5.529 PAPD4
PAP associated domain containing 4
chrX_-_119133802 5.477 NM_139282
RHOXF1
Rhox homeobox family, member 1
chr14_-_64638809 5.383 MAX
MYC associated factor X
chr19_+_3317575 5.267 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr1_-_154318412 5.177 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr20_-_47618059 5.141 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr2_-_163403274 5.051 KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr13_-_107665871 5.046 NM_206937
LIG4
ligase IV, DNA, ATP-dependent
chr22_-_41913002 4.947 TTLL12
tubulin tyrosine ligase-like family, member 12
chr4_+_191245840 4.908 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr16_+_28741873 4.818 ATXN2L
ataxin 2-like
chr4_+_191232653 4.695 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chrX_+_53095230 4.650 NM_018969
GPR173
G protein-coupled receptor 173
chrX_-_101658297 4.533 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr16_+_28741908 4.496 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr12_-_53071285 4.466 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr19_+_3317536 4.447 NM_005597
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr16_+_28741861 4.437 ATXN2L
ataxin 2-like
chr22_-_41913076 4.437 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr22_-_30929463 4.385 NM_001098527
RFPL2
ret finger protein-like 2
chr19_+_4442610 4.377 HDGFRP2
hepatoma-derived growth factor-related protein 2
chr2_+_5750229 4.368 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr21_-_43368963 4.215 NM_000071
CBS
cystathionine-beta-synthase
chrX_-_1291526 4.134 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr22_-_41913075 4.131 TTLL12
tubulin tyrosine ligase-like family, member 12
chr7_+_65731364 4.052 KCTD7
potassium channel tetramerisation domain containing 7
chr11_+_65311104 3.977 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr21_-_43369492 3.963 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr3_+_171621721 3.951 NM_001185056
CLDN11
claudin 11
chrX_-_151057615 3.912 NM_001011543
NM_021048
MAGEA10

melanoma antigen family A, 10

chr4_+_191226073 3.870 NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr19_+_659766 3.835 NM_001040134
NM_002579
PALM

paralemmin

chrX_+_152561086 3.808 NM_001395
DUSP9
dual specificity phosphatase 9
chr20_-_21326046 3.802 NM_033176
NKX2-4
NK2 homeobox 4
chr1_-_23623713 3.663 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr16_+_28742066 3.652 ATXN2L
ataxin 2-like
chr4_-_5941043 3.645 CRMP1
collapsin response mediator protein 1
chr10_-_103525646 3.634 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr11_-_76059435 3.630 NM_001128922
LRRC32
leucine rich repeat containing 32
chr10_+_135333667 3.588 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr11_-_27678551 3.560 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chrX_-_137621492 3.519 NM_004114
FGF13
fibroblast growth factor 13
chr3_+_194441586 3.509 NM_020386
HRASLS
HRAS-like suppressor
chr5_+_92946348 3.492 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_148155986 3.485 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr4_-_5941167 3.479 NM_001313
CRMP1
collapsin response mediator protein 1
chr1_-_154484341 3.448 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr19_-_15421761 3.377 NM_021241
WIZ
widely interspaced zinc finger motifs
chr1_+_1066138 3.364


chr11_+_65311142 3.361 OVOL1
ovo-like 1(Drosophila)
chr22_+_49459935 3.347 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr3_-_71715431 3.329 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr11_+_56984702 3.291 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chrX_+_153466611 3.291 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chrX_-_48578878 3.259 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr4_+_191242540 3.257 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr7_-_100331417 3.251 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr17_-_44047299 3.242 NM_024016
HOXB8
homeobox B8
chr11_+_359723 3.213 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr20_-_26137755 3.177 LOC284801
hypothetical protein LOC284801
chr4_+_191239247 3.173 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr16_+_1143241 3.170 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr1_+_2975590 3.168 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr10_+_135343649 3.164 NM_012147
DUX2
double homeobox 2
chr20_-_62151216 3.150 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr1_-_182273114 3.143 GLT25D2
glycosyltransferase 25 domain containing 2
chr13_-_113066202 3.127 GRTP1
growth hormone regulated TBC protein 1
chr14_+_28305922 3.103 NM_005249
FOXG1
forkhead box G1
chrX_+_102471769 3.071 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chrX_-_39841599 3.063 NM_001123385
NM_017745
BCOR

BCL6 corepressor

chr21_-_44506526 3.052 NM_013369
NM_175867
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chr11_-_8695974 3.045 ST5
suppression of tumorigenicity 5
chr2_-_163403485 3.036 NM_033272
NM_173162
KCNH7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr11_-_76058542 3.031 NM_005512
LRRC32
leucine rich repeat containing 32
chr20_-_62071584 3.023 NM_020713
ZNF512B
zinc finger protein 512B
chr3_-_48607596 3.017 NM_000094
COL7A1
collagen, type VII, alpha 1
chr8_-_41624030 3.015 NM_152568
NKX6-3
NK6 homeobox 3
chr16_+_1143738 3.005 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr10_-_126839000 2.994 CTBP2
C-terminal binding protein 2
chr11_-_69228286 2.948 NM_005117
FGF19
fibroblast growth factor 19
chr10_+_83625049 2.941 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr19_-_55763091 2.928 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr19_+_56506907 2.925 NM_001101372
IGLON5
IgLON family member 5
chr11_-_27679022 2.923 NM_001143812
BDNF
brain-derived neurotrophic factor
chr8_-_125252884 2.910 C8orf78
chromosome 8 open reading frame 78
chr8_+_99508425 2.905 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr17_-_60208083 2.891 LOC146880
hypothetical LOC146880
chr4_+_191229360 2.865 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr2_+_10101081 2.848 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr8_-_111056099 2.838 NM_014379
KCNV1
potassium channel, subfamily V, member 1
chr12_+_50686990 2.835 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chrX_+_151617900 2.810 NM_005363
NM_175868
MAGEA6

melanoma antigen family A, 6

chr20_+_48032918 2.797 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr15_-_54544531 2.791 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr13_-_36392370 2.785 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr5_+_128823904 2.784 NM_133638
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr2_+_235525355 2.781 NM_014521
SH3BP4
SH3-domain binding protein 4
chr18_+_75261231 2.778 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr12_+_52665196 2.767 NM_017409
HOXC10
homeobox C10
chr15_-_49174107 2.764 TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr9_-_115901157 2.763 NM_138424
KIF12
kinesin family member 12
chr11_-_6633427 2.755 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr17_+_26742903 2.738 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr4_+_3264509 2.717 RGS12
regulator of G-protein signaling 12
chr19_+_40213431 2.682 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr19_+_38979502 2.669 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr17_-_74361975 2.662 TIMP2
TIMP metallopeptidase inhibitor 2
chr6_-_48144344 2.657 NM_001013732
NM_207499
C6orf138

chromosome 6 open reading frame 138

chr1_+_1940605 2.648 NM_000815
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr15_-_72952648 2.636 NM_005697
SCAMP2
secretory carrier membrane protein 2
chr19_-_13478037 2.630 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr3_-_41978464 2.629 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chr16_+_86194075 2.602 JPH3
junctophilin 3
chr16_+_88517187 2.598 NM_006086
TUBB3
tubulin, beta 3
chrX_+_128501862 2.598 NM_000276
NM_001587
OCRL

oculocerebrorenal syndrome of Lowe

chr1_+_154318954 2.596 LMNA
lamin A/C
chr12_+_6808025 2.591 LEPREL2
leprecan-like 2
chr15_+_22644448 2.591


chrX_-_131918905 2.577 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr15_-_43267139 2.572 SHF
Src homology 2 domain containing F
chr12_-_21818881 2.567 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr3_+_213430 2.535 CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chrX_-_148476903 2.525 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr2_-_219881937 2.523 PTPRN
protein tyrosine phosphatase, receptor type, N
chrX_-_152139267 2.518 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr10_-_64248932 2.502 NM_001136178
EGR2
early growth response 2
chr10_+_135330357 2.501 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chrX_-_151688850 2.486 NM_005362
MAGEA3
melanoma antigen family A, 3
chr2_+_242679507 2.480 LOC728323
hypothetical LOC728323
chr5_-_136862130 2.469 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_135161185 2.464 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr10_-_135000358 2.457 CALY
calcyon neuron-specific vesicular protein
chr7_-_127833231 2.452 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr19_+_3831675 2.443 ATCAY
ataxia, cerebellar, Cayman type
chrX_+_148671394 2.434 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr7_-_526005 2.429 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr11_-_88864061 2.422 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr13_-_107665130 2.413 NM_002312
LIG4
ligase IV, DNA, ATP-dependent
chr6_+_12120709 2.411 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr3_-_159306214 2.410


chr3_+_112273352 2.404 PVRL3
poliovirus receptor-related 3
chr3_+_50629593 2.392 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr14_-_20563698 2.391 NDRG2
NDRG family member 2
chr3_+_213535 2.379 NM_006614
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chrX_+_113724806 2.373 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chr11_-_118799058 2.368 THY1
Thy-1 cell surface antigen
chr14_+_102458745 2.358 NM_030943
AMN
amnionless homolog (mouse)
chr14_+_68796621 2.358 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr19_+_57492236 2.338 NM_144684
ZNF480
zinc finger protein 480
chr1_-_75854281 2.333 SLC44A5
solute carrier family 44, member 5
chr22_+_47350781 2.328 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr14_-_20563722 2.320 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr16_+_68516401 2.294 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr12_+_50271283 2.285 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr3_-_116348780 2.271 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_65731289 2.270 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr17_+_58908152 2.259 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr11_-_2115077 2.252


chr19_+_522260 2.251 NM_198591
BSG
basigin (Ok blood group)
chr7_-_150129295 2.242 NM_014020
TMEM176B
transmembrane protein 176B
chr17_-_34014390 2.225 SRCIN1
SRC kinase signaling inhibitor 1
chr3_+_50629604 2.204 NM_004635
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chrX_-_71442488 2.203 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr14_-_64638974 2.198 NM_002382
NM_145112
NM_145113
NM_145114
NM_145116
NM_197957
MAX





MYC associated factor X





chr3_+_129355006 2.193 EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA-specific
chrX_-_47394937 2.188 NM_001114123
NM_005229
ELK1

ELK1, member of ETS oncogene family

chr1_+_15123165 2.187 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr13_-_76499297 2.186 NM_012158
FBXL3
F-box and leucine-rich repeat protein 3
chr17_+_75366524 2.177 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr12_-_47679176 2.177 NM_015086
DDN
dendrin
chr19_-_5291700 2.170 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr19_-_15204767 2.169 NM_001142886
EPHX3
epoxide hydrolase 3
chr3_+_129354995 2.156 NM_021937
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA-specific

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.68 6.92e-18 GO:0007399 nervous system development
2.00 7.65e-15 GO:0048731 system development
1.85 3.97e-14 GO:0007275 multicellular organismal development
1.80 4.69e-14 GO:0032502 developmental process
1.87 7.41e-13 GO:0048856 anatomical structure development
2.10 1.92e-10 GO:0048513 organ development
2.02 8.04e-10 GO:0030154 cell differentiation
2.67 9.92e-10 GO:0022008 neurogenesis
1.37 1.47e-09 GO:0065007 biological regulation
1.52 1.63e-09 GO:0032501 multicellular organismal process
1.98 2.04e-09 GO:0048869 cellular developmental process
2.70 2.30e-09 GO:0048699 generation of neurons
1.40 8.98e-09 GO:0050794 regulation of cellular process
2.28 1.13e-08 GO:0051239 regulation of multicellular organismal process
1.37 2.45e-08 GO:0050789 regulation of biological process
2.14 2.56e-08 GO:0009653 anatomical structure morphogenesis
2.51 4.36e-08 GO:0048468 cell development
1.77 9.62e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.72 2.60e-07 GO:0060284 regulation of cell development
1.71 6.76e-07 GO:0051171 regulation of nitrogen compound metabolic process
2.37 1.87e-06 GO:0050793 regulation of developmental process
1.78 2.42e-06 GO:0051252 regulation of RNA metabolic process
2.62 2.71e-06 GO:0045595 regulation of cell differentiation
2.52 2.80e-06 GO:2000026 regulation of multicellular organismal development
3.70 4.33e-06 GO:0051960 regulation of nervous system development
2.89 4.82e-06 GO:0007417 central nervous system development
1.79 4.90e-06 GO:0048523 negative regulation of cellular process
1.78 5.55e-06 GO:0006355 regulation of transcription, DNA-dependent
2.56 5.59e-06 GO:0030182 neuron differentiation
2.91 6.38e-06 GO:0019226 transmission of nerve impulse
2.91 6.38e-06 GO:0035637 multicellular organismal signaling
1.68 6.84e-06 GO:0031326 regulation of cellular biosynthetic process
1.73 1.02e-05 GO:0048519 negative regulation of biological process
1.66 1.32e-05 GO:0009889 regulation of biosynthetic process
2.65 1.47e-05 GO:0009887 organ morphogenesis
2.51 2.21e-05 GO:0031327 negative regulation of cellular biosynthetic process
2.79 2.98e-05 GO:0000904 cell morphogenesis involved in differentiation
1.54 3.23e-05 GO:0080090 regulation of primary metabolic process
2.46 4.14e-05 GO:0009890 negative regulation of biosynthetic process
1.53 4.38e-05 GO:0031323 regulation of cellular metabolic process
3.01 5.12e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.67 8.28e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.07 8.63e-05 GO:0007420 brain development
2.57 1.16e-04 GO:0048666 neuron development
2.83 1.34e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.14 1.40e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.64 1.69e-04 GO:0010556 regulation of macromolecule biosynthetic process
2.46 1.75e-04 GO:0032989 cellular component morphogenesis
2.78 2.01e-04 GO:0048812 neuron projection morphogenesis
2.29 2.47e-04 GO:0007267 cell-cell signaling
2.57 2.62e-04 GO:0051253 negative regulation of RNA metabolic process
1.46 2.65e-04 GO:0019222 regulation of metabolic process
2.47 3.27e-04 GO:0000902 cell morphogenesis
1.48 3.58e-04 GO:0023052 signaling
1.61 4.14e-04 GO:0010468 regulation of gene expression
2.55 4.58e-04 GO:0045892 negative regulation of transcription, DNA-dependent
2.06 4.62e-04 GO:0007154 cell communication
3.42 4.79e-04 GO:0050767 regulation of neurogenesis
2.42 5.48e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.15 5.99e-04 GO:0040011 locomotion
2.75 6.00e-04 GO:0007409 axonogenesis
1.58 6.26e-04 GO:0048518 positive regulation of biological process
1.50 7.43e-04 GO:0060255 regulation of macromolecule metabolic process
2.39 7.55e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
4.05 7.98e-04 GO:0006813 potassium ion transport
2.55 1.03e-03 GO:0048858 cell projection morphogenesis
2.66 1.23e-03 GO:0007268 synaptic transmission
2.52 1.26e-03 GO:0032990 cell part morphogenesis
1.59 1.51e-03 GO:0048522 positive regulation of cellular process
1.76 1.66e-03 GO:0023051 regulation of signaling
2.07 1.86e-03 GO:0031324 negative regulation of cellular metabolic process
2.52 1.89e-03 GO:0031175 neuron projection development
2.24 2.14e-03 GO:0009790 embryo development
2.27 2.77e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.81 3.56e-03 GO:0007389 pattern specification process
4.21 4.45e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
4.17 4.94e-03 GO:0022604 regulation of cell morphogenesis
3.42 5.15e-03 GO:0045664 regulation of neuron differentiation
2.25 6.11e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.79 6.70e-03 GO:0007411 axon guidance
4.04 7.38e-03 GO:0042391 regulation of membrane potential
2.26 7.39e-03 GO:0010629 negative regulation of gene expression
2.78 1.06e-02 GO:0001501 skeletal system development
11.40 1.36e-02 GO:0017158 regulation of calcium ion-dependent exocytosis
1.98 1.60e-02 GO:0009888 tissue development
2.58 1.74e-02 GO:0009792 embryo development ending in birth or egg hatching
2.38 1.86e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.86 1.92e-02 GO:0010646 regulation of cell communication
1.89 2.26e-02 GO:0009892 negative regulation of metabolic process
1.60 2.57e-02 GO:0048583 regulation of response to stimulus
2.13 2.80e-02 GO:0030030 cell projection organization
3.59 3.15e-02 GO:0060562 epithelial tube morphogenesis
2.13 3.81e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.71 3.93e-02 GO:0048729 tissue morphogenesis
1.70 4.04e-02 GO:0009966 regulation of signal transduction
2.51 4.09e-02 GO:0043009 chordate embryonic development
2.51 4.09e-02 GO:0048598 embryonic morphogenesis
2.00 4.22e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53 4.67e-02 GO:0065008 regulation of biological quality

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.09 7.71e-07 GO:0045202 synapse
1.61 3.06e-04 GO:0044459 plasma membrane part
3.29 7.40e-04 GO:0034702 ion channel complex
2.86 9.37e-04 GO:0044456 synapse part
1.37 1.36e-03 GO:0005886 plasma membrane
1.35 3.12e-03 GO:0071944 cell periphery
2.41 5.80e-03 GO:0043005 neuron projection
2.10 6.72e-03 GO:0030054 cell junction
3.55 9.56e-03 GO:0034703 cation channel complex
4.32 1.03e-02 GO:0008076 voltage-gated potassium channel complex
4.32 1.03e-02 GO:0034705 potassium channel complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.11 2.48e-12 GO:0043565 sequence-specific DNA binding
2.60 3.72e-11 GO:0001071 nucleic acid binding transcription factor activity
2.60 3.72e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
2.26 3.49e-07 GO:0030528 transcription regulator activity
4.82 2.12e-06 GO:0022843 voltage-gated cation channel activity
4.02 1.09e-05 GO:0005244 voltage-gated ion channel activity
4.02 1.09e-05 GO:0022832 voltage-gated channel activity
3.07 9.29e-05 GO:0022836 gated channel activity
3.70 9.39e-05 GO:0010843 promoter binding
2.78 1.07e-04 GO:0005216 ion channel activity
2.74 1.50e-04 GO:0022838 substrate-specific channel activity
3.56 1.85e-04 GO:0000975 regulatory region DNA binding
3.56 1.85e-04 GO:0001067 regulatory region nucleic acid binding
3.56 1.85e-04 GO:0044212 transcription regulatory region DNA binding
2.66 2.91e-04 GO:0015267 channel activity
4.34 3.00e-04 GO:0005267 potassium channel activity
2.96 3.00e-04 GO:0016564 transcription repressor activity
2.65 3.07e-04 GO:0022803 passive transmembrane transporter activity
4.89 3.46e-04 GO:0005249 voltage-gated potassium channel activity
2.98 1.18e-03 GO:0005261 cation channel activity
1.54 2.80e-03 GO:0003677 DNA binding
2.65 5.45e-03 GO:0016563 transcription activator activity
10.69 2.55e-02 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
10.69 2.55e-02 GO:0019198 transmembrane receptor protein phosphatase activity
25.64 3.54e-02 GO:0051380 norepinephrine binding
1.75 3.74e-02 GO:0005102 receptor binding