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Motif ID: SMAD1..7,9.p2

Z-value: 2.496

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_60475558	3.342	NM_016582	SLC15A3	solute carrier family 15, member 3
chr22_+_23221114	2.552	NM_016327	UPB1	ureidopropionase, beta
chr17_+_19377732	2.350	NM_018242	SLC47A1	solute carrier family 47, member 1
chr10_+_135333667	2.096	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_191229360	2.071	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_191242540	2.030	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr11_+_60626505	2.004	NM_014207	CD5	CD5 molecule
chr10_+_135330357	1.986	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr1_+_20751518	1.900	NM_207334	FAM43B	family with sequence similarity 43, member B
chr9_-_139183675	1.848
chr3_+_44601457	1.814	NM_173658	ZNF660	zinc finger protein 660
chr10_+_135343649	1.810	NM_012147	DUX2	double homeobox 2
chrX_+_102749489	1.739	NM_001006933 NM_032926	TCEAL3	transcription elongation factor A (SII)-like 3
chr22_-_22970850	1.738	NM_001099781 NM_001099782 NM_004121	GGT5	gamma-glutamyltransferase 5
chr4_+_191232653	1.725	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr17_-_33753218	1.714	NM_001004334	GPR179	G protein-coupled receptor 179
chr3_-_129689394	1.640	NM_001145662	GATA2	GATA binding protein 2
chr4_+_191226073	1.622	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr16_+_56219802	1.615	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr5_+_113725914	1.615	NM_021614	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr9_-_96441654	1.613	NM_000507	FBP1	fructose-1,6-bisphosphatase 1
chr8_+_143542378	1.612	NM_001702	BAI1	brain-specific angiogenesis inhibitor 1
chr21_+_44844924	1.595	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr11_+_113436438	1.594	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr13_-_32822759	1.579		STARD13	StAR-related lipid transfer (START) domain containing 13
chr11_-_18769703	1.571	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr21_+_44818033	1.566	NM_198687	KRTAP10-4	keratin associated protein 10-4
chr22_+_21318779	1.560	NM_199127	GGTLC2	gamma-glutamyltransferase light chain 2
chr8_+_22465368	1.520		SORBS3	sorbin and SH3 domain containing 3
chr2_+_176761552	1.493	NM_024501	HOXD1	homeobox D1
chrX_+_53095230	1.470	NM_018969	GPR173	G protein-coupled receptor 173
chr1_+_15964045	1.464	NM_001024216	FBLIM1	filamin binding LIM protein 1
chr1_-_6368324	1.462	NM_181864	ACOT7	acyl-CoA thioesterase 7
chr1_-_45444812	1.459	NM_020883	ZSWIM5	zinc finger, SWIM-type containing 5
chrX_-_102870207	1.457	NM_001024452 NM_001172285	GLRA4	glycine receptor, alpha 4
chrX_+_44588192	1.422	NM_022076	DUSP21	dual specificity phosphatase 21
chr15_-_50869379	1.416	NM_004498	ONECUT1	one cut homeobox 1
chr4_+_191239247	1.407	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr21_+_44881700	1.391	NM_181688	KRTAP10-10	keratin associated protein 10-10
chr9_-_96441567	1.342		FBP1	fructose-1,6-bisphosphatase 1
chr1_-_202595666	1.338	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr1_+_8928508	1.333	NM_001215	CA6	carbonic anhydrase VI
chr1_+_3558958	1.321	NM_005427	TP73	tumor protein p73
chr14_+_51850754	1.317	NM_000956	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa
chr15_-_70385709	1.314	NM_001172685	CELF6	CUGBP, Elav-like family member 6
chrX_+_101862297	1.311	NM_001142524 NM_001142525 NM_001142526 NM_001142527 NM_001142528 NM_030639	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr4_+_191235959	1.309	NM_001177376	DUX4L4	double homeobox 4 like 4
chr7_-_150283794	1.306	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_148610516	1.301		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr17_-_70099964	1.288	NM_001115152	CD300LD	CD300 molecule-like family member d
chr15_-_88143721	1.286		ANPEP	alanyl (membrane) aminopeptidase
chr3_+_16901455	1.260	NM_001144382	PLCL2	phospholipase C-like 2
chr15_+_64782468	1.234		SMAD6	SMAD family member 6
chr1_+_63561632	1.213		FOXD3	forkhead box D3
chr3_-_51968995	1.212		PCBP4	poly(rC) binding protein 4
chrX_+_152682772	1.192	NM_001163257 NM_005393	PLXNB3	plexin B3
chr8_+_22493928	1.181	NM_176871 NM_198042	PDLIM2	PDZ and LIM domain 2 (mystique)
chr22_+_23153529	1.172	NM_000675	ADORA2A	adenosine A2a receptor
chr10_+_125415860	1.153	NM_153442	GPR26	G protein-coupled receptor 26
chr10_-_70846573	1.138	NM_001057	TACR2	tachykinin receptor 2
chr11_-_70350292	1.136		SHANK2	SH3 and multiple ankyrin repeat domains 2
chr12_+_48641545	1.135	NM_001651	AQP5	aquaporin 5
chr22_-_29290875	1.123	NM_004861	GAL3ST1	galactose-3-O-sulfotransferase 1
chr1_+_210864411	1.121	NM_153606	FAM71A	family with sequence similarity 71, member A
chr9_-_96442351	1.095	NM_001127628	FBP1	fructose-1,6-bisphosphatase 1
chr5_+_113726203	1.093		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_157408000	1.074	NM_021189 NM_001127173	CADM3	cell adhesion molecule 3
chr21_-_44784499	1.068	NM_198691	KRTAP10-1	keratin associated protein 10-1
chr3_+_11009419	1.066	NM_003042	SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr10_-_82106479	1.063	NM_138812	DYDC1	DPY30 domain containing 1
chr13_+_95541093	1.057	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr8_-_131483395	1.057	NM_018482	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr4_+_55218663	1.056	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr12_-_121780835	1.054	NM_032554	GPR81	G protein-coupled receptor 81
chr9_-_115101140	1.046	NM_145051	RNF183	ring finger protein 183
chr7_+_142459538	1.045	NM_001001667	OR6V1	olfactory receptor, family 6, subfamily V, member 1
chr11_-_70350509	1.045		SHANK2	SH3 and multiple ankyrin repeat domains 2
chr9_-_96442377	1.039		FBP1	fructose-1,6-bisphosphatase 1
chr11_+_74548472	1.036	NM_001145211	SLCO2B1	solute carrier organic anion transporter family, member 2B1
chr1_-_202432165	1.026	NM_002256	KISS1	KiSS-1 metastasis-suppressor
chr19_-_40684638	1.022	NM_001035516	DMKN	dermokine
chr9_+_125813849	1.016		LHX2	LIM homeobox 2
chr20_-_23915431	1.015	NM_178312	GGTLC1	gamma-glutamyltransferase light chain 1
chr19_+_3659358	0.999		TJP3	tight junction protein 3 (zona occludens 3)
chr8_+_21971317	0.997	NM_001114135	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr19_+_40534284	0.990	NM_005303	FFAR1	free fatty acid receptor 1
chr12_-_56496107	0.976	NM_006576	AVIL	advillin
chr11_-_116199145	0.974	NM_000482	APOA4	apolipoprotein A-IV
chr12_+_50104936	0.972		SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr19_-_56221681	0.965	NM_001136032	KLK11	kallikrein-related peptidase 11
chrX_+_101853912	0.965	NM_001004051 NM_001184874 NM_001184875 NM_001184876 NM_138437	GPRASP2	G protein-coupled receptor associated sorting protein 2
chr9_-_96441409	0.960		FBP1	fructose-1,6-bisphosphatase 1
chr6_+_110406890	0.950	NM_005284	GPR6	G protein-coupled receptor 6
chr3_-_50324815	0.931	NM_153281	HYAL1	hyaluronoglucosaminidase 1
chr1_-_1840564	0.927	NM_178545	TMEM52	transmembrane protein 52
chr12_+_55896844	0.922	NM_007224	NXPH4	neurexophilin 4
chrX_-_135941498	0.921	NM_054021	GPR101	G protein-coupled receptor 101
chr2_-_31659472	0.916	NM_000348	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
chr19_+_9064854	0.914	NM_001004456	OR1M1	olfactory receptor, family 1, subfamily M, member 1
chr11_-_17522430	0.910	NM_005709 NM_153676	USH1C	Usher syndrome 1C (autosomal recessive, severe)
chr1_-_31618405	0.909	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr9_+_128764324	0.908	NM_001190728	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr14_+_99273751	0.903		EML1	echinoderm microtubule associated protein like 1
chr19_-_46626474	0.887	NM_198540	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr17_-_42411587	0.883	NM_203400	RPRML	reprimo-like
chr19_+_4180494	0.881	NM_005755	EBI3	Epstein-Barr virus induced 3
chr22_+_42137955	0.881	NM_001044370	MPPED1	metallophosphoesterase domain containing 1
chrX_+_71318250	0.881	NM_001170747 NM_006223	PIN4	protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr10_+_82106537	0.879	NM_032372	DYDC2	DPY30 domain containing 2
chrX_-_114703273	0.875
chr7_+_154493478	0.875	NM_024012	HTR5A	5-hydroxytryptamine (serotonin) receptor 5A
chr19_-_41034734	0.875	NM_004646	NPHS1	nephrosis 1, congenital, Finnish type (nephrin)
chr21_-_44803049	0.870	NM_198696	KRTAP10-3	keratin associated protein 10-3
chr6_-_25834733	0.863	NM_170745	HIST1H2AA	histone cluster 1, H2aa
chr1_+_24713396	0.861		RCAN3	RCAN family member 3
chrX_+_103297891	0.860	NM_207318	FAM199X	family with sequence similarity 199, X-linked
chr1_-_154913712	0.852	NM_006617	NES	nestin
chr8_-_143820825	0.851	NM_020427	SLURP1	secreted LY6/PLAUR domain containing 1
chr19_-_16145285	0.847	NM_054113	CIB3	calcium and integrin binding family member 3
chr1_-_164402575	0.847	NM_001017961	FAM78B	family with sequence similarity 78, member B
chr1_+_63561317	0.841	NM_012183	FOXD3	forkhead box D3
chr1_-_218168548	0.838	NM_018713	SLC30A10	solute carrier family 30, member 10
chr19_+_40465249	0.836	NM_021175	HAMP	hepcidin antimicrobial peptide
chr7_-_44195405	0.836	NM_000162	GCK	glucokinase (hexokinase 4)
chr22_+_42138034	0.833		MPPED1	metallophosphoesterase domain containing 1
chr6_-_26038817	0.832	NM_005835	SLC17A2	solute carrier family 17 (sodium phosphate), member 2
chr12_+_50104859	0.831	NM_001039960 NM_004858	SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr19_+_2200112	0.827	NM_000479	AMH	anti-Mullerian hormone
chrX_-_50573759	0.824	NM_020717	SHROOM4	shroom family member 4
chr11_+_122901543	0.824		GRAMD1B	GRAM domain containing 1B
chr4_+_9392355	0.820	NM_000798	DRD5	dopamine receptor D5
chr7_-_105106844	0.817	NM_138495	ATXN7L1	ataxin 7-like 1
chr16_-_3783475	0.815		CREBBP	CREB binding protein
chr21_+_46370831	0.811		COL6A2	collagen, type VI, alpha 2
chr3_+_42702014	0.810	NM_152393	KBTBD5	kelch repeat and BTB (POZ) domain containing 5
chr11_+_47564805	0.808	NM_001164379	FAM180B	family with sequence similarity 180, member B
chrX_-_128616594	0.801	NM_017413	APLN	apelin
chrX_-_125127760	0.800	NM_001013628	DCAF12L2	DDB1 and CUL4 associated factor 12-like 2
chrX_+_102727068	0.800	NM_001006935 NM_001006937 NM_024863	TCEAL4	transcription elongation factor A (SII)-like 4
chr5_+_156628929	0.798	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chrX_-_106846684	0.797		TSC22D3	TSC22 domain family, member 3
chr2_+_97717300	0.792	NM_207519	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa
chr22_+_18330049	0.790	NM_007310	COMT	catechol-O-methyltransferase
chr4_+_191245840	0.789	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chrX_-_62487693	0.788	NM_001012968	SPIN4	spindlin family, member 4
chr21_+_43462209	0.783	NM_000394	CRYAA	crystallin, alpha A
chr1_-_201321999	0.782	NM_002479	MYOG	myogenin (myogenic factor 4)
chr2_+_70981233	0.781		VAX2	ventral anterior homeobox 2
chr2_+_71016503	0.780	NM_001692	ATP6V1B1	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr15_-_97368546	0.774	NM_001167902	PGPEP1L	pyroglutamyl-peptidase I-like
chrX_-_108754906	0.768	NM_012282	KCNE1L	KCNE1-like
chr22_+_21407066	0.767
chr17_-_24357014	0.759	NM_001098635 NM_178860	SEZ6	seizure related 6 homolog (mouse)
chrX_+_49531209	0.759	NM_001145073	USP27X	ubiquitin specific peptidase 27, X-linked
chr16_-_47872973	0.757		CBLN1	cerebellin 1 precursor
chr21_-_31175722	0.754	NM_175858	KRTAP11-1	keratin associated protein 11-1
chr1_+_178466064	0.753	NM_033343	LHX4	LIM homeobox 4
chr19_-_53808505	0.751	NM_017708	FAM83E	family with sequence similarity 83, member E
chr11_-_65860450	0.750	NM_004292	RIN1	Ras and Rab interactor 1
chrX_-_114374860	0.749	NM_020871	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2
chr18_-_43821491	0.746	NM_001039360	ZBTB7C	zinc finger and BTB domain containing 7C
chr6_-_24466258	0.745	NM_016356	DCDC2	doublecortin domain containing 2
chr1_+_226261374	0.744	NM_033131	WNT3A	wingless-type MMTV integration site family, member 3A
chr11_+_1420250	0.742		BRSK2	BR serine/threonine kinase 2
chr3_+_46717826	0.741	NM_147196	TMIE	transmembrane inner ear
chr7_-_76667045	0.738	NM_006682	FGL2	fibrinogen-like 2
chr22_-_20235372	0.736	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr21_-_30614477	0.735	NM_203405	KRTAP26-1	keratin associated protein 26-1
chr19_-_56105805	0.733	NM_004917	KLK4	kallikrein-related peptidase 4
chr17_+_43128422	0.732
chr7_-_27108826	0.731	NM_006735	HOXA2	homeobox A2
chr15_+_72253940	0.731	NM_201526	ISLR	immunoglobulin superfamily containing leucine-rich repeat
chr7_+_128367961	0.726	NM_001098627	IRF5	interferon regulatory factor 5
chr3_-_62835601	0.721
chr4_-_673107	0.720		MFSD7	major facilitator superfamily domain containing 7
chr2_+_70981223	0.715	NM_012476	VAX2	ventral anterior homeobox 2
chr7_+_75977680	0.715	NM_030570 NM_182684	UPK3B	uroplakin 3B
chrX_-_2896285	0.715		ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chr21_+_44890758	0.714	NM_198692	KRTAP10-11	keratin associated protein 10-11
chr17_-_17421050	0.713		PEMT	phosphatidylethanolamine N-methyltransferase
chr18_-_45630154	0.711		MYO5B	myosin VB
chrX_+_70438352	0.710	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr9_-_115880281	0.706		AMBP	alpha-1-microglobulin/bikunin precursor
chr17_-_23965305	0.703	NM_001174103	SGK494	uncharacterized serine/threonine-protein kinase SgK494
chr1_+_226712430	0.701	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr7_+_70235724	0.700	NM_022479	WBSCR17	Williams-Beuren syndrome chromosome region 17
chr21_+_44871467	0.700	NM_198690	KRTAP10-9	keratin associated protein 10-9
chr3_-_15515382	0.699	NM_080538	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr8_+_142501188	0.697	NM_007079 NM_032611	PTP4A3	protein tyrosine phosphatase type IVA, member 3
chr7_+_73080362	0.692	NM_000501 NM_001081752 NM_001081753 NM_001081754 NM_001081755	ELN	elastin
chr22_-_35835548	0.692		TMPRSS6	transmembrane protease, serine 6
chrX_-_37916138	0.692		SRPX	sushi-repeat containing protein, X-linked
chr3_+_52325374	0.685	NM_015512	DNAH1	dynein, axonemal, heavy chain 1
chr1_+_100776280	0.680	NM_022049	GPR88	G protein-coupled receptor 88
chr7_+_73080404	0.677		ELN	elastin
chr16_+_8714326	0.675	NM_000663	ABAT	4-aminobutyrate aminotransferase
chrX_-_12972641	0.673	NM_174901	FAM9C	family with sequence similarity 9, member C
chr15_+_39918302	0.672	NM_001114633	PLA2G4B	phospholipase A2, group IVB (cytosolic)
chrX_-_74062005	0.672	NM_001008537	KIAA2022	KIAA2022
chr11_-_60379998	0.672	NM_004778	GPR44	G protein-coupled receptor 44

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
11.84	2.48e-02	GO:0045095	keratin filament
7.09	4.77e-02	GO:0005882	intermediate filament

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.31	1.95e-05	GO:0001071	nucleic acid binding transcription factor activity
4.31	1.95e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
5.12	3.56e-05	GO:0043565	sequence-specific DNA binding
118.24	1.22e-04	GO:0003840	gamma-glutamyltransferase activity
37.35	5.70e-03	GO:0016755	transferase activity, transferring amino-acyl groups