Motif ID: SOX5.p2

Z-value: 1.721


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5



Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_16380967 3.693 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr12_-_24606616 2.658 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr6_+_12398514 2.212 NM_001168319
NM_001955
EDN1

endothelin 1

chr6_+_21774624 2.135 FLJ22536
hypothetical locus LOC401237
chr21_+_42492867 2.112 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr3_+_174598937 2.038 NM_014932
NLGN1
neuroligin 1
chr7_+_128802719 1.964 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr11_+_20005704 1.878 NAV2
neuron navigator 2
chr1_+_50344550 1.866 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_-_111633428 1.866 DOCK4
dedicator of cytokinesis 4
chr7_-_11838260 1.720 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr11_-_119104463 1.692 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr5_-_125956996 1.589 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr1_+_183970093 1.574 NM_031935
HMCN1
hemicentin 1
chr16_+_65938753 1.417 NM_001161575
LRRC36
leucine rich repeat containing 36
chr11_+_5925152 1.406 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr17_-_10393664 1.404 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr2_-_128138435 1.384 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr12_-_66905802 1.382 NM_018402
IL26
interleukin 26
chr21_-_38792173 1.341 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr7_-_27108826 1.313 NM_006735
HOXA2
homeobox A2
chr6_+_155579788 1.280 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_+_8928508 1.272 NM_001215
CA6
carbonic anhydrase VI
chr4_+_42590038 1.260 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr20_-_29457650 1.246 NM_001011878
DEFB121
defensin, beta 121
chr7_+_134226690 1.234 NM_033139
NM_033140
CALD1

caldesmon 1

chr20_-_49612574 1.227 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr10_+_118295417 1.185 NM_000936
PNLIP
pancreatic lipase
chrX_+_107174855 1.183 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr7_-_111633620 1.169 NM_014705
DOCK4
dedicator of cytokinesis 4
chr1_-_7998265 1.164 ERRFI1
ERBB receptor feedback inhibitor 1
chr1_+_12757570 1.150 NM_001080830
PRAMEF12
PRAME family member 12
chr2_-_21084077 1.144 APOB
apolipoprotein B (including Ag(x) antigen)
chr20_-_49612745 1.140 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr5_+_38439399 1.128 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr11_+_113280727 1.102 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr3_-_150533948 1.091 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr3_+_173954940 1.084 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr1_+_2927905 1.083 NM_080431
ACTRT2
actin-related protein T2
chr3_+_189425886 1.080 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr7_+_134226727 1.065 CALD1
caldesmon 1
chr15_+_100175888 1.064 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chrX_-_10548458 1.064 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr2_+_38009405 1.063 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr6_+_31190505 1.048 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr16_+_85169615 1.039 NM_005250
FOXL1
forkhead box L1
chrX_-_99778340 1.036 NM_003270
TSPAN6
tetraspanin 6
chr1_+_184532027 1.028 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr11_+_4799126 1.023 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr1_-_229627412 1.004 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr1_-_204455269 0.998 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr5_-_168204430 0.987


chr3_-_194118321 0.985 MB21D2
Mab-21 domain containing 2
chr2_+_169631777 0.978 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_-_160599779 0.968 NM_003058
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr10_-_61819493 0.965 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_128910132 0.940 ANGPTL2
angiopoietin-like 2
chr2_-_1905508 0.934 MYT1L
myelin transcription factor 1-like
chr2_+_69093641 0.933 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr5_-_71838875 0.932 NM_152625
ZNF366
zinc finger protein 366
chr8_-_18585721 0.931 PSD3
pleckstrin and Sec7 domain containing 3
chr6_+_148705817 0.928 SASH1
SAM and SH3 domain containing 1
chrX_+_135079461 0.922 NM_001167819
FHL1
four and a half LIM domains 1
chr6_-_116973465 0.921 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr6_+_148705421 0.911 NM_015278
SASH1
SAM and SH3 domain containing 1
chr10_+_18280773 0.906 NM_001145195
NM_152725
SLC39A12

solute carrier family 39 (zinc transporter), member 12

chr8_+_7731402 0.902 NM_080389
NM_001040702
DEFB104A
DEFB104B
defensin, beta 104A
defensin, beta 104B
chr6_-_29752909 0.902 NM_001109809
ZFP57
zinc finger protein 57 homolog (mouse)
chr11_-_4555625 0.901 NM_144663
C11orf40
chromosome 11 open reading frame 40
chr6_-_138935359 0.896 NM_020464
NHSL1
NHS-like 1
chrX_+_123062143 0.879 STAG2
stromal antigen 2
chr1_+_559129 0.870


chr7_+_93373755 0.866 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr20_+_58004811 0.866 NM_021810
CDH26
cadherin 26
chr17_+_3047559 0.863 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chrX_-_15312390 0.857 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr4_-_152316105 0.857 NM_001128924
SH3D19
SH3 domain containing 19
chr1_-_230717850 0.851 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr3_+_88270951 0.849 NM_018293
ZNF654
zinc finger protein 654
chr8_-_108579270 0.839 NM_001146
ANGPT1
angiopoietin 1
chr15_+_37330176 0.834 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr9_+_116943917 0.820 NM_017418
DEC1
deleted in esophageal cancer 1
chr4_+_37655385 0.820 TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr7_-_27171673 0.819 NM_152739
HOXA9
homeobox A9
chr4_-_170314382 0.817 SH3RF1
SH3 domain containing ring finger 1
chr12_+_32546243 0.814 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_+_3056307 0.808 NM_175612
CNTN4
contactin 4
chr7_+_116238309 0.802 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr12_-_103846186 0.794 NM_032148
SLC41A2
solute carrier family 41, member 2
chr12_+_54172413 0.790 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr2_-_133144094 0.788 LYPD1
LY6/PLAUR domain containing 1
chr7_+_153633127 0.787 NM_001936
DPP6
dipeptidyl-peptidase 6
chr2_+_27573206 0.787 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr7_-_16811131 0.784 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chrX_+_130019896 0.778 NM_144967
ARHGAP36
Rho GTPase activating protein 36
chr3_+_182900081 0.777 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr6_-_138581319 0.777 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr12_-_109842736 0.768 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr9_+_27099138 0.765 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr7_-_139948780 0.760 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr15_+_69220841 0.759 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chr11_+_19328846 0.758 NM_001111018
NAV2
neuron navigator 2
chr3_-_194118627 0.757 NM_178496
MB21D2
Mab-21 domain containing 2
chr6_-_42527760 0.752 NM_033502
TRERF1
transcriptional regulating factor 1
chr3_-_47909001 0.742 MAP4
microtubule-associated protein 4
chr17_+_63252704 0.742 BPTF
bromodomain PHD finger transcription factor
chr1_-_154484341 0.741 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr9_-_72673753 0.737 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chrX_-_110541029 0.734 NM_000555
DCX
doublecortin
chr1_+_33494745 0.728 NM_152493
ZNF362
zinc finger protein 362
chr9_+_129066576 0.727 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr14_-_88953059 0.723 NM_005197
FOXN3
forkhead box N3
chr4_+_124537334 0.722 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_69289889 0.722 NM_002837
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_+_161305188 0.717 NM_005613
RGS4
regulator of G-protein signaling 4
chrX_-_19727828 0.704 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr4_-_185376012 0.702 NM_153343
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr7_+_29486010 0.701 NM_001039936
CHN2
chimerin (chimaerin) 2
chrX_-_50573759 0.701 NM_020717
SHROOM4
shroom family member 4
chr9_-_129557373 0.698 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr8_+_42671718 0.690 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr4_+_120029426 0.679 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr5_-_148738980 0.678 NM_014443
IL17B
interleukin 17B
chr7_+_142850667 0.664 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr13_+_23742846 0.664 SPATA13
spermatogenesis associated 13
chr5_+_55182963 0.663 NM_139017
IL31RA
interleukin 31 receptor A
chr1_+_151442542 0.662 NM_001010857
LELP1
late cornified envelope-like proline-rich 1
chr9_-_4142182 0.660 NM_152629
GLIS3
GLIS family zinc finger 3
chrX_+_135079120 0.660 NM_001159704
FHL1
four and a half LIM domains 1
chr10_-_116434364 0.655 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr7_-_26198673 0.654 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_-_51976428 0.650 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr9_+_115265827 0.641 NM_017790
RGS3
regulator of G-protein signaling 3
chr3_-_58627509 0.638 NM_138805
FAM3D
family with sequence similarity 3, member D
chr10_+_86121526 0.635 FAM190B
family with sequence similarity 190, member B
chr15_+_57286313 0.634 NM_033195
LDHAL6B
lactate dehydrogenase A-like 6B
chr7_+_111633878 0.631 NM_021994
ZNF277
zinc finger protein 277
chr6_-_29120930 0.625 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr10_-_108914277 0.624 NM_001013031
NM_052918
SORCS1

sortilin-related VPS10 domain containing receptor 1

chr6_-_139654807 0.624 NM_153235
TXLNB
taxilin beta
chr12_+_26096757 0.623 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_+_61697209 0.622 NFIA
nuclear factor I/A
chrX_+_107569671 0.622 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr6_-_132064233 0.621 NM_030908
OR2A4
olfactory receptor, family 2, subfamily A, member 4
chr2_-_160181206 0.620 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_-_202730135 0.619 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chrX_+_15435351 0.614 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr17_-_31332568 0.610 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr19_-_14800275 0.610 NM_017506
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr5_-_38631263 0.609 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr7_+_111633972 0.608 ZNF277
zinc finger protein 277
chr12_-_98072602 0.606 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr18_-_27594696 0.603 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr2_-_73170290 0.601 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr2_-_56266408 0.601 LOC100129434
hypothetical LOC100129434
chr1_+_199975674 0.598 NAV1
neuron navigator 1
chr6_-_24985432 0.595 NM_015864
FAM65B
family with sequence similarity 65, member B
chr11_+_5862076 0.592 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr15_+_60146467 0.592 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr4_-_24523605 0.587 NM_001130726
CCDC149
coiled-coil domain containing 149
chr2_-_160838397 0.586 RBMS1
RNA binding motif, single stranded interacting protein 1
chr4_+_141397889 0.582 NM_032547
SCOC
short coiled-coil protein
chr1_+_61642287 0.581 NFIA
nuclear factor I/A
chr3_+_44571600 0.579 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr9_+_123501186 0.574 DAB2IP
DAB2 interacting protein
chr1_-_85703198 0.572 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr10_+_69539255 0.565 NM_032578
MYPN
myopalladin
chr19_+_3958690 0.565 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr7_-_143587653 0.562 NM_001005328
OR2A7
OR2A4
olfactory receptor, family 2, subfamily A, member 7
olfactory receptor, family 2, subfamily A, member 4
chr9_-_96442377 0.560 FBP1
fructose-1,6-bisphosphatase 1
chr13_-_93929719 0.559 NM_001129889
NM_001922
DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

chr8_-_93144039 0.558


chr16_+_31105579 0.555


chr5_-_88155360 0.554 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr18_-_13905534 0.553 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr3_-_11585264 0.549 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr19_-_56164628 0.549 NM_002774
KLK6
kallikrein-related peptidase 6
chr14_-_93493519 0.548 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr3_+_25444753 0.547 NM_016152
RARB
retinoic acid receptor, beta
chr1_+_116727514 0.546 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_-_40140126 0.545 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr20_+_30019465 0.544 NM_001011718
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr8_-_6783193 0.544 NM_001925
DEFA4
defensin, alpha 4, corticostatin
chr1_+_68070573 0.541


chr7_-_130891861 0.539 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr12_+_54132264 0.538 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr1_-_68470585 0.538 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr17_-_46479127 0.538 SPAG9
sperm associated antigen 9
chr3_-_126215069 0.537 HEG1
HEG homolog 1 (zebrafish)
chr16_+_55373241 0.536 NUP93
nucleoporin 93kDa
chr12_+_47498778 0.536 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr9_+_109131814 0.535 RAD23B
RAD23 homolog B (S. cerevisiae)
chr4_-_184478920 0.535 NM_001111319
CLDN22
claudin 22
chr7_-_150555153 0.534 NM_005692
NM_007189
ABCF2

ATP-binding cassette, sub-family F (GCN20), member 2

chrX_+_114701432 0.532 NM_005032
PLS3
plastin 3
chr2_+_178893216 0.532 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr5_-_121842680 0.531


chr15_+_40427592 0.528 NM_212465
CAPN3
calpain 3, (p94)
chr1_+_29113589 0.528 NM_001166006
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr6_-_24491498 0.527 NM_001195610
DCDC2
doublecortin domain containing 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
11.17 3.10e-02 GO:0005912 adherens junction
10.09 4.56e-02 GO:0070161 anchoring junction

Nothing significant found in function category.