Motif ID: SPI1.p2

Z-value: 2.075


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1



Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_26395420 1.482 NM_001145168
NM_001145169
GPR113

G protein-coupled receptor 113

chr6_-_32265489 1.451 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr6_-_33016561 1.401 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_-_152663748 1.399 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr20_-_32877029 1.373 NM_014071
NCOA6
nuclear receptor coactivator 6
chr2_-_148494732 1.362 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr14_-_37134050 1.279 FOXA1
forkhead box A1
chr6_-_144427340 1.272 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr14_-_37134191 1.270 NM_004496
FOXA1
forkhead box A1
chr2_+_138438277 1.252 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr22_-_35938298 1.179 NM_001051
SSTR3
somatostatin receptor 3
chr1_-_146543102 1.151


chr3_-_11736946 1.147 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr12_+_25096472 1.145 NM_006152
LRMP
lymphoid-restricted membrane protein
chr2_+_17861266 1.094 NM_001105569
MSGN1
mesogenin 1
chr12_-_56422120 1.054 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr16_-_87570716 1.031 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_+_66244314 1.015 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr12_+_25096755 1.011 LRMP
lymphoid-restricted membrane protein
chr11_-_18226743 1.008 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr14_-_37133927 1.002 FOXA1
forkhead box A1
chr17_-_55824083 0.991 USP32
ubiquitin specific peptidase 32
chr17_+_53625084 0.982 NM_000502
EPX
eosinophil peroxidase
chr20_-_22512893 0.956 FOXA2
forkhead box A2
chr1_+_36462625 0.951 THRAP3
thyroid hormone receptor associated protein 3
chr2_-_152663454 0.949 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_-_183210155 0.943 FAM129A
family with sequence similarity 129, member A
chr6_+_31651319 0.927 NM_000594
TNF
tumor necrosis factor
chr2_-_72228427 0.927 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr20_+_21231921 0.914 NM_012255
XRN2
5'-3' exoribonuclease 2
chr11_+_18244383 0.908 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr1_-_146398501 0.904 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr11_+_85017269 0.897 NM_001193537
NM_001193538
NM_018480
TMEM126B


transmembrane protein 126B


chr2_+_73973600 0.896 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr3_-_196644864 0.893 NM_012287
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr11_+_120828058 0.893 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr14_+_31616196 0.883 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr2_+_148495043 0.882 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr2_+_73973640 0.882 ACTG2
actin, gamma 2, smooth muscle, enteric
chr17_+_44643067 0.879 ABI3
ABI family, member 3
chr20_+_42947754 0.876 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr2_-_139254273 0.852 NM_007226
NXPH2
neurexophilin 2
chr10_-_5531401 0.842 NM_017422
CALML5
calmodulin-like 5
chr2_-_152664056 0.811 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_-_4113777 0.811 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr2_-_55500450 0.809 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr2_+_190981257 0.794 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr6_+_21701942 0.793 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr17_-_24302450 0.788 PHF12
PHD finger protein 12
chr1_+_159899528 0.775 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr1_-_142535878 0.761 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr9_-_26882713 0.760 NM_001167575
NM_024828
C9orf82

chromosome 9 open reading frame 82

chr5_+_49998528 0.760 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr3_+_120495906 0.754 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr3_-_121295202 0.746 GSK3B
glycogen synthase kinase 3 beta
chr17_+_35046843 0.746 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr1_-_183210296 0.745 NM_052966
FAM129A
family with sequence similarity 129, member A
chr5_+_49998677 0.745 PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_-_31658044 0.736 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr2_-_148495642 0.731 NM_181742
ORC4
origin recognition complex, subunit 4
chr17_+_44642587 0.731 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr14_-_22354389 0.728 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr15_+_72687765 0.728 NM_003992
CLK3
CDC-like kinase 3
chr2_-_74259308 0.720 NM_018221
MOBKL1B
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr20_-_22513050 0.719 NM_021784
FOXA2
forkhead box A2
chr20_+_42947764 0.717 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr2_-_201461945 0.714 NM_032472
NM_130906
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr12_+_53241365 0.713 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr14_-_22358752 0.713 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr20_-_62208627 0.710 NM_005286
NPBWR2
neuropeptides B/W receptor 2
chr7_+_114350144 0.706 MDFIC
MyoD family inhibitor domain containing
chr1_+_168767864 0.704 NM_001146039
NM_152281
GORAB

golgin, RAB6-interacting

chr11_+_63864263 0.701 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr3_-_107070400 0.701 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr6_+_30702586 0.692 NM_024909
NM_001031722
NM_001190724
ATAT1


alpha tubulin acetyltransferase 1


chr6_+_30693464 0.691 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr2_-_180580024 0.686 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr16_+_28413421 0.682 NM_018690
APOBR
apolipoprotein B receptor
chr14_-_22354457 0.677 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr20_+_3661316 0.676 NM_001197327
NM_052970
HSPA12B

heat shock 70kD protein 12B

chr7_-_104440707 0.674 LOC100216545
hypothetical LOC100216545
chr1_+_239762179 0.664 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_-_47125788 0.659 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr15_-_21444085 0.656 NM_019066
MAGEL2
MAGE-like 2
chr2_-_60634271 0.653 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr1_+_32512298 0.652 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr19_-_47328399 0.650 NM_002698
POU2F2
POU class 2 homeobox 2
chr4_+_39376058 0.646 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)


chr1_-_52791309 0.645 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr9_-_99740243 0.643 NM_197978
HEMGN
hemogen
chr14_-_30746577 0.633


chr3_-_126576693 0.633 NM_021964
ZNF148
zinc finger protein 148
chr9_-_5997891 0.628 NM_001017969
KIAA2026
KIAA2026
chr15_+_83724743 0.626 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr11_-_46099531 0.626 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr2_+_68445936 0.625 PLEK
pleckstrin
chr11_+_72658586 0.620 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr5_-_142795269 0.619 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr2_+_48395271 0.618 NM_002158
FOXN2
forkhead box N2
chr2_+_217206450 0.617 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr19_-_10311262 0.610 NM_002162
ICAM3
intercellular adhesion molecule 3
chr5_+_176951802 0.608 NM_017510
TMED9
transmembrane emp24 protein transport domain containing 9
chr2_+_60836858 0.608 NM_022894
PAPOLG
poly(A) polymerase gamma
chr16_-_69030421 0.606 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr3_-_15348811 0.602 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr12_+_118590039 0.596 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr17_-_40655347 0.593 LOC339192
hypothetical LOC339192
chr17_-_70901303 0.591 GRB2
growth factor receptor-bound protein 2
chr7_+_107171809 0.589 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr12_+_118911859 0.588 NM_207311
CCDC64
coiled-coil domain containing 64
chr12_-_53664722 0.586 NM_001136030
KIAA0748
KIAA0748
chr3_-_131948202 0.586 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr8_-_15140162 0.584 NM_139167
SGCZ
sarcoglycan, zeta
chr11_+_116520181 0.580 NM_001184746
NM_001184747
NM_001184748
NM_002572
PAFAH1B2



platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)



chr14_-_23090606 0.577 NM_033400
ZFHX2
zinc finger homeobox 2
chr4_-_84595967 0.576 NM_133636
HELQ
helicase, POLQ-like
chr1_+_9634368 0.573 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr12_+_27568311 0.570 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr20_-_35318690 0.568 NM_001184731
NM_021081
GHRH

growth hormone releasing hormone

chr6_+_31690957 0.566 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr11_+_65026382 0.565


chr11_-_101828563 0.563 NM_052932
TMEM123
transmembrane protein 123
chrX_-_17789276 0.560 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr6_-_125664913 0.560 NM_016063
HDDC2
HD domain containing 2
chr2_-_231498184 0.558 NM_005683
GPR55
G protein-coupled receptor 55
chr14_-_30746431 0.558 NM_015382
HECTD1
HECT domain containing 1
chr20_+_30329096 0.557 NM_004798
KIF3B
kinesin family member 3B
chr6_-_8047731 0.555 NM_001135650
NM_004280
EEF1E1

eukaryotic translation elongation factor 1 epsilon 1

chr14_-_34413831 0.554 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr5_+_140454382 0.554 NM_018936
PCDHB2
protocadherin beta 2
chr1_+_36462583 0.553 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr22_-_30018329 0.552 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr17_-_44642934 0.552 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_-_32299757 0.552 NM_004557
NOTCH4
notch 4
chr17_-_31441390 0.552 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr2_-_174537021 0.551 NM_001017371
SP3
Sp3 transcription factor
chr6_+_57290357 0.550 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr2_+_85051687 0.550 NM_020122
KCMF1
potassium channel modulatory factor 1
chr20_+_762355 0.549 NM_001042353
FAM110A
family with sequence similarity 110, member A
chr7_+_128651976 0.547 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chr16_-_21197072 0.546 CRYM
crystallin, mu
chr18_+_30875297 0.541 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr20_+_3138055 0.540 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr17_+_40655060 0.539 NM_005892
FMNL1
formin-like 1
chr14_-_22354851 0.535 NM_001126105
NM_003982
SLC7A7

solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

chr6_+_152053323 0.534 NM_001122742
ESR1
estrogen receptor 1
chr6_-_119137923 0.533 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr17_+_25828546 0.532 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr6_+_73388713 0.532 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr2_-_202811459 0.530 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr4_+_84596141 0.528 NM_016067
MRPS18C
mitochondrial ribosomal protein S18C
chr17_-_34860840 0.525 NM_004774
MED1
mediator complex subunit 1
chr2_+_227737524 0.518 NM_000091
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr14_+_22305570 0.517 NM_005015
OXA1L
oxidase (cytochrome c) assembly 1-like
chr2_-_88136362 0.516 NM_016618
KRCC1
lysine-rich coiled-coil 1
chr14_-_47213906 0.515 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr10_+_73703682 0.515 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr4_+_71986927 0.513 NM_173468
MOBKL1A
MOB1, Mps One Binder kinase activator-like 1A (yeast)
chr20_+_16658608 0.513 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr15_-_41381744 0.512 NM_052955
TGM7
transglutaminase 7
chr2_-_197883569 0.512 ANKRD44
ankyrin repeat domain 44
chr6_-_56816403 0.511 DST
dystonin
chr11_+_57066689 0.510 NM_001105565
SMTNL1
smoothelin-like 1
chr12_+_60940404 0.507 NM_006313
USP15
ubiquitin specific peptidase 15
chr2_-_88136394 0.505 KRCC1
lysine-rich coiled-coil 1
chr18_-_50004770 0.505 MBD2
methyl-CpG binding domain protein 2
chr8_+_21956335 0.505 NM_003867
FGF17
fibroblast growth factor 17
chr2_+_27659396 0.502 NM_032434
ZNF512
zinc finger protein 512
chr2_+_217071764 0.502 NM_000998
RPL37A
ribosomal protein L37a
chr12_+_56374004 0.500 NM_001017956
NM_001017957
NM_001017958
NM_006812
OS9



osteosarcoma amplified 9, endoplasmic reticulum lectin



chr2_+_218790364 0.499 NM_005731
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr4_+_56509793 0.499 NM_025009
CEP135
centrosomal protein 135kDa
chr16_-_29664765 0.496 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr2_+_71412348 0.495 NM_001014972
NM_014497
ZNF638

zinc finger protein 638

chr12_+_56230047 0.492 KIF5A
kinesin family member 5A
chr14_-_38709161 0.492 NM_001079537
NM_177452
TRAPPC6B

trafficking protein particle complex 6B

chr16_-_21197138 0.491 CRYM
crystallin, mu
chr2_-_122210873 0.489 NM_032390
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein
chr16_+_56134037 0.489 GPR114
G protein-coupled receptor 114
chr2_+_218698980 0.487 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr7_+_104959767 0.484 NM_021930
RINT1
RAD50 interactor 1
chr16_+_29725311 0.484 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr3_-_150858274 0.484 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr10_+_101409159 0.484 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr16_+_30112707 0.483 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr1_+_233558863 0.481 GGPS1
geranylgeranyl diphosphate synthase 1
chr2_+_219780192 0.480 ZFAND2B
zinc finger, AN1-type domain 2B
chr15_+_87919744 0.480 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr2_+_85051942 0.480 KCMF1
potassium channel modulatory factor 1
chr2_+_187163232 0.480 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr12_+_48003237 0.479 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr16_-_73292188 0.477 NM_001142497
NM_152649
MLKL

mixed lineage kinase domain-like

chr4_+_689529 0.476 NM_006315
PCGF3
polycomb group ring finger 3
chr6_+_31648071 0.475 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr10_+_124310170 0.474 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr12_+_91620749 0.473 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_-_205186330 0.472 NM_002644
PIGR
polymeric immunoglobulin receptor
chr3_-_15349086 0.471 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr2_+_218790143 0.470 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr7_+_119700924 0.470 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.