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Motif ID: SREBF1,2.p2

Z-value: 0.896

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_+_48582389	1.826	NM_014923	FNDC3A	fibronectin type III domain containing 3A
chr2_+_234333653	1.707	NM_000463	UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1
chr2_+_227898163	1.553		MFF	mitochondrial fission factor
chr20_+_37024383	1.479	NM_001190809 NM_021931	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_+_177785667	1.427	NM_194247	HNRNPA3P1 HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 heterogeneous nuclear ribonucleoprotein A3
chr14_-_34253473	1.339	NM_138638	CFL2	cofilin 2 (muscle)
chr6_-_84994032	1.250	NM_014895	KIAA1009	KIAA1009
chr2_-_176575171	1.192	NM_030650	KIAA1715	KIAA1715
chr10_+_45542653	1.130	NM_001169106 NM_001169107 NM_015262	FAM21C FAM21A	family with sequence similarity 21, member C family with sequence similarity 21, member A
chr17_-_44022595	1.108		HOXB3	homeobox B3
chr11_-_85457469	1.094		PICALM	phosphatidylinositol binding clathrin assembly protein
chr6_+_35852369	1.094	NM_207409	C6orf126	chromosome 6 open reading frame 126
chr20_-_43953036	1.091	NM_080749	NEURL2	neuralized homolog 2 (Drosophila)
chr6_-_7258351	1.089	NM_003144	SSR1	signal sequence receptor, alpha
chr11_+_85017269	1.050	NM_001193537 NM_001193538 NM_018480	TMEM126B	transmembrane protein 126B
chr17_-_41018291	1.050
chr14_-_67353046	1.044	NM_015346	ZFYVE26	zinc finger, FYVE domain containing 26
chr20_+_43953428	1.037		CTSA	cathepsin A
chr16_+_55580910	1.037	NM_032206	NLRC5	NLR family, CARD domain containing 5
chr10_-_45410197	1.034	NM_001002265 NM_145021	MARCH8	membrane-associated ring finger (C3HC4) 8
chr20_+_43953372	1.008		CTSA	cathepsin A
chr10_+_69314714	0.951		SIRT1	sirtuin 1
chr2_+_187266899	0.946	NM_177454	FAM171B	family with sequence similarity 171, member B
chr2_-_131567458	0.945	NM_001009993	FAM168B	family with sequence similarity 168, member B
chr3_-_20202622	0.938	NM_001012409 NM_001012410 NM_001012411 NM_001012412 NM_001012413 NM_138484	SGOL1	shugoshin-like 1 (S. pombe)
chr6_-_169392771	0.927
chr4_-_23500706	0.925	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_+_176724583	0.911
chr2_-_27399405	0.908	NM_002437	MPV17	MpV17 mitochondrial inner membrane protein
chr7_-_44496703	0.899	NM_015332	NUDCD3	NudC domain containing 3
chr1_+_224337937	0.883
chr20_+_43953331	0.879		CTSA	cathepsin A
chr6_+_127629677	0.878	NM_030963	RNF146	ring finger protein 146
chr3_-_11736946	0.878	NM_014667	VGLL4	vestigial like 4 (Drosophila)
chr13_+_112999590	0.868		LAMP1	lysosomal-associated membrane protein 1
chr2_+_241174803	0.863	NM_023083 NM_023085	CAPN10	calpain 10
chr7_-_134845363	0.860	NM_001008225 NM_001190847 NM_001190848 NM_001190849 NM_001190850 NM_013316	CNOT4	CCR4-NOT transcription complex, subunit 4
chr20_+_33506322	0.858	NM_007186	CEP250	centrosomal protein 250kDa
chr16_+_68542126	0.852	NM_001136214	CLEC18A	C-type lectin domain family 18, member A
chr11_+_125586828	0.850	NM_024556	FAM118B	family with sequence similarity 118, member B
chr2_+_176724358	0.844	NM_014621	HOXD4	homeobox D4
chr22_+_34107087	0.839		HMOX1	heme oxygenase (decycling) 1
chr1_-_152797820	0.839		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_139391511	0.837	NM_021243	C6orf115	chromosome 6 open reading frame 115
chr5_+_41940216	0.831	NM_175921	C5orf51	chromosome 5 open reading frame 51
chr2_+_85676347	0.822	NM_016494	RNF181	ring finger protein 181
chr6_+_160310118	0.811	NM_000876	IGF2R	insulin-like growth factor 2 receptor
chr16_+_68542310	0.807	NM_182619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr19_+_10626106	0.803		ILF3	interleukin enhancer binding factor 3, 90kDa
chr1_+_76312962	0.777	NM_001160011 NM_152996	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr13_-_78131259	0.777	NM_024546	RNF219	ring finger protein 219
chr16_-_1465007	0.772		CLCN7	chloride channel 7
chr1_+_159550789	0.761	NM_001035511 NM_001035512 NM_001035513 NM_003001	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr16_-_1465041	0.741	NM_001114331 NM_001287	CLCN7	chloride channel 7
chr6_+_7671267	0.738		BMP6	bone morphogenetic protein 6
chr11_-_85457736	0.730		PICALM	phosphatidylinositol binding clathrin assembly protein
chr1_-_152797707	0.727	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_151815298	0.725		C6orf211	chromosome 6 open reading frame 211
chr5_+_133735004	0.724		UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr1_-_152797760	0.719		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr4_+_17225344	0.715	NM_025205	MED28	mediator complex subunit 28
chr16_+_5023672	0.705		LOC100507589	hypothetical LOC100507589
chr1_-_152797767	0.698		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_139391570	0.691		C6orf115	chromosome 6 open reading frame 115
chr16_-_15644465	0.688	NM_001184998 NM_001184999 NM_014647	KIAA0430	KIAA0430
chr20_+_33823318	0.684	NM_016436	PHF20	PHD finger protein 20
chr20_-_32877029	0.684	NM_014071	NCOA6	nuclear receptor coactivator 6
chr10_+_69314347	0.676	NM_012238	SIRT1	sirtuin 1
chr16_-_1464927	0.668		CLCN7	chloride channel 7
chr16_-_5023562	0.663		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr15_-_71712605	0.658		NPTN	neuroplastin
chr7_+_27190688	0.657
chr20_+_46971618	0.648	NM_006420	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr20_+_18066473	0.642	NM_001164811	PET117	cytochrome c oxidase assembly factor-like
chr6_-_21631992	0.639
chr7_-_135083906	0.638	NM_205855	FAM180A	family with sequence similarity 180, member A
chr14_-_23981493	0.635	NM_020195	SDR39U1	short chain dehydrogenase/reductase family 39U, member 1
chr16_+_80370426	0.627	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr6_-_163754903	0.626		LOC100526820	hypothetical LOC100526820
chr8_-_54918099	0.626	NM_213620	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr6_-_26767892	0.623	NM_024639	ZNF322A	zinc finger protein 322A
chr16_-_1465021	0.623		CLCN7	chloride channel 7
chr3_+_87359088	0.618	NM_014043	CHMP2B	chromatin modifying protein 2B
chr11_-_85457753	0.618	NM_001008660 NM_007166	PICALM	phosphatidylinositol binding clathrin assembly protein
chr17_-_27210330	0.604	NM_018405	C17orf79	chromosome 17 open reading frame 79
chr1_+_10015736	0.603		UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)
chr1_+_109221271	0.594		GPSM2	G-protein signaling modulator 2
chr8_+_98725505	0.589	NM_178812	MTDH	metadherin
chr1_-_201162991	0.588	NM_021633	KLHL12	kelch-like 12 (Drosophila)
chr17_-_43977273	0.587	NM_002145	HOXB2	homeobox B2
chr13_-_32757835	0.584	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr14_-_23752507	0.581		CHMP4A	chromatin modifying protein 4A
chr1_+_234372454	0.579	NM_003272	GPR137B	G protein-coupled receptor 137B
chr16_+_22124870	0.576	NM_013302	EEF2K	eukaryotic elongation factor-2 kinase
chr14_+_30161267	0.562	NM_016106 NM_182835	SCFD1	sec1 family domain containing 1
chr8_-_95343716	0.562	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr3_+_150330060	0.561	NM_032383	HPS3	Hermansky-Pudlak syndrome 3
chr2_+_46779827	0.559	NM_144949	SOCS5	suppressor of cytokine signaling 5
chr14_-_23752476	0.555		CHMP4A	chromatin modifying protein 4A
chr14_-_23752498	0.554		CHMP4A	chromatin modifying protein 4A
chr9_-_130749604	0.552	NM_014908	DOLK	dolichol kinase
chr1_+_109963982	0.550		AMPD2	adenosine monophosphate deaminase 2
chr2_-_200424140	0.547		LOC348751	hypothetical LOC348751
chr19_-_15436333	0.546	NM_022904	RASAL3	RAS protein activator like 3
chr16_+_83618804	0.545	NM_014732	KIAA0513	KIAA0513
chr22_+_34107051	0.543	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr19_-_13088212	0.541	NM_001142554 NM_017722 NM_001136035	TRMT1	TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)
chr3_-_126257425	0.541	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr17_-_44043361	0.538	NM_004502	HOXB7	homeobox B7
chr17_-_34263487	0.535	NM_000978	SNORA21 RPL23	small nucleolar RNA, H/ACA box 21 ribosomal protein L23
chr17_+_52410466	0.533	NM_021626	SCPEP1	serine carboxypeptidase 1
chr16_+_28893525	0.532	NM_001142448 NM_001142449 NM_001142450 NM_001142451 NM_032038	SPIN1 SPNS1	spindlin 1 spinster homolog 1 (Drosophila)
chr20_-_61317891	0.532	NM_017798	YTHDF1	YTH domain family, member 1
chr8_-_81246215	0.529	NM_001025253 NM_005079	TPD52	tumor protein D52
chr6_-_31973418	0.529		EHMT2	euchromatic histone-lysine N-methyltransferase 2
chr1_-_201162938	0.526		KLHL12	kelch-like 12 (Drosophila)
chr1_-_77920914	0.520	NM_015534	ZZZ3	zinc finger, ZZ-type containing 3
chr1_+_149750485	0.520	NM_020770	CGN	cingulin
chr17_-_7078304	0.520		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr2_-_105312536	0.518	NM_001142621 NM_004257	TGFBRAP1	transforming growth factor, beta receptor associated protein 1
chr17_-_73636386	0.518	NM_001127198	TMC6	transmembrane channel-like 6
chr6_+_151815114	0.513	NM_024573	C6orf211	chromosome 6 open reading frame 211
chr17_-_44042924	0.513		HOXB7	homeobox B7
chr10_-_120504445	0.513		C10orf46	chromosome 10 open reading frame 46
chr6_-_43305156	0.513	NM_006443 NM_199184	C6orf108	chromosome 6 open reading frame 108
chr2_-_148494732	0.512	NM_001190882 NM_001190879 NM_002552 NM_001190881 NM_181741	ORC4	origin recognition complex, subunit 4
chr17_-_40263124	0.512	NM_005497	GJC1	gap junction protein, gamma 1, 45kDa
chr12_-_47396724	0.505	NM_001240	CCNT1	cyclin T1
chr4_-_84152985	0.503	NM_001115007	LIN54	lin-54 homolog (C. elegans)
chr12_+_54396118	0.501		BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chr11_-_125586733	0.501	NM_001144827 NM_032795	RPUSD4	RNA pseudouridylate synthase domain containing 4
chr14_+_37746937	0.500	NM_001049	SSTR1	somatostatin receptor 1
chr16_+_80036275	0.499	NM_198390	CMIP	c-Maf-inducing protein
chr8_-_95343696	0.498		GEM	GTP binding protein overexpressed in skeletal muscle
chr8_+_98725604	0.497		MTDH	metadherin
chr20_+_18496068	0.497		LOC388789	hypothetical LOC388789
chr5_-_55564942	0.487	NM_024669	ANKRD55	ankyrin repeat domain 55
chr20_-_4743768	0.486	NM_170774	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr11_-_1741680	0.482		CTSD	cathepsin D
chr17_-_33043514	0.481	NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882	SYNRG	synergin, gamma
chr17_-_7078446	0.480	NM_004422	DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr2_-_210743622	0.480		C2orf67	chromosome 2 open reading frame 67
chr14_-_38971370	0.478	NM_203301	FBXO33	F-box protein 33
chr1_+_181871830	0.477	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr1_+_109963950	0.476	NM_139156	AMPD2	adenosine monophosphate deaminase 2
chr22_+_38903825	0.476	NM_001162501 NM_015088	TNRC6B	trinucleotide repeat containing 6B
chr17_+_63252704	0.474		BPTF	bromodomain PHD finger transcription factor
chr2_-_196744546	0.474	NM_004226	STK17B	serine/threonine kinase 17b
chr17_-_73636362	0.474		TMC6	transmembrane channel-like 6
chr10_+_101532544	0.472		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr14_-_93512818	0.470		ASB2	ankyrin repeat and SOCS box containing 2
chr4_-_152901542	0.470	NM_004564	PET112L	PET112-like (yeast)
chr6_-_31973434	0.470	NM_006709 NM_025256	EHMT2	euchromatic histone-lysine N-methyltransferase 2
chr2_+_223625105	0.467	NM_080671	KCNE4	potassium voltage-gated channel, Isk-related family, member 4
chr20_+_43952997	0.467	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr16_+_80370400	0.466		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr17_-_7078399	0.466		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr17_-_44043278	0.465		HOXB7	homeobox B7
chr9_-_139128777	0.464		DPP7	dipeptidyl-peptidase 7
chr14_-_34661190	0.463	NM_017917	PPP2R3C	protein phosphatase 2, regulatory subunit B'', gamma
chr14_+_22860511	0.462		PABPN1	poly(A) binding protein, nuclear 1
chr6_-_44333002	0.462	NM_178148	SLC35B2	solute carrier family 35, member B2
chr5_+_122138636	0.461	NM_003100	SNX2	sorting nexin 2
chr16_+_15644624	0.457	NM_001143979	NDE1	nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr5_-_172130766	0.456	NM_004417	DUSP1	dual specificity phosphatase 1
chr7_+_97574054	0.456	NM_014916	LMTK2	lemur tyrosine kinase 2
chr2_-_215605054	0.453	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr12_-_119826073	0.452		SPPL3	signal peptide peptidase 3
chr18_-_20231709	0.449		OSBPL1A	oxysterol binding protein-like 1A
chr9_-_124707314	0.449	NM_001100588 NM_018835	RC3H2	ring finger and CCCH-type domains 2
chr6_-_80713589	0.448	NM_022726	ELOVL4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr6_-_152664906	0.442		SYNE1	spectrin repeat containing, nuclear envelope 1
chr2_+_46779553	0.441	NM_014011	SOCS5	suppressor of cytokine signaling 5
chr14_-_34661156	0.441		PPP2R3C	protein phosphatase 2, regulatory subunit B'', gamma
chr10_+_101532450	0.439	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr17_+_63252087	0.438	NM_004459 NM_182641	BPTF	bromodomain PHD finger transcription factor
chr16_-_57276108	0.438	NM_018231	SLC38A7	solute carrier family 38, member 7
chr16_+_11669736	0.437	NM_003498	SNN	stannin
chr20_-_34102250	0.437		LOC647979	hypothetical LOC647979
chr5_+_122138661	0.436		SNX2	sorting nexin 2
chr6_-_33822659	0.435	NM_001142883 NM_054111	IP6K3	inositol hexakisphosphate kinase 3
chr1_+_36462583	0.434	NM_005119	THRAP3	thyroid hormone receptor associated protein 3
chr16_-_87450734	0.433		GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr2_-_175741096	0.432	NM_001880	ATF2	activating transcription factor 2
chr11_-_8849485	0.431		ST5	suppression of tumorigenicity 5
chr5_+_122138677	0.430		SNX2	sorting nexin 2
chr11_-_6597220	0.429		TPP1	tripeptidyl peptidase I
chr11_+_120828275	0.428		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr10_-_120504267	0.428
chr1_-_154532019	0.427	NM_144580	C1orf85	chromosome 1 open reading frame 85
chr17_-_71362971	0.424	NM_012478	WBP2	WW domain binding protein 2
chr1_+_36462625	0.424		THRAP3	thyroid hormone receptor associated protein 3
chr7_-_27190882	0.423		HOXA11	homeobox A11
chr11_+_66915997	0.423	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chr2_+_68238490	0.422	NM_020143	PNO1	partner of NOB1 homolog (S. cerevisiae)
chr16_+_4837912	0.421	NM_001079514	UBN1	ubinuclein 1
chr8_+_98725670	0.419		MTDH	metadherin
chr11_-_1741663	0.418		CTSD	cathepsin D
chr9_-_135379888	0.415	NM_001080483	TMEM8C	transmembrane protein 8C
chr17_+_46599081	0.415	NM_001018138	NME2	non-metastatic cells 2, protein (NM23B) expressed in

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
44.27	2.36e-03	GO:0031901	early endosome membrane
147.45	4.80e-03	GO:0071203	WASH complex
16.94	4.09e-02	GO:0005769	early endosome

Nothing significant found in function category.