Motif ID: STAT2,4,6.p2

Z-value: 1.767


Transcription factors associated with STAT2,4,6.p2:

Gene SymbolEntrez IDGene Name
STAT2 6773 signal transducer and activator of transcription 2, 113kDa
STAT4 6775 signal transducer and activator of transcription 4
STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced



Activity profile for motif STAT2,4,6.p2.

activity profile for motif STAT2,4,6.p2


Sorted Z-values histogram for motif STAT2,4,6.p2

Sorted Z-values for motif STAT2,4,6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT2,4,6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_188945921 3.920 BCL6
B-cell CLL/lymphoma 6
chr17_-_73867748 3.612 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr10_-_126706442 2.194 NM_022802
CTBP2
C-terminal binding protein 2
chr3_-_188946168 2.185 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr20_+_2743613 1.896 NM_080739
C20orf141
chromosome 20 open reading frame 141
chr2_-_86186441 1.726 POLR1A
polymerase (RNA) I polypeptide A, 194kDa
chr2_+_69974581 1.711 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr1_-_68071635 1.682 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr20_-_48741481 1.549


chr2_-_178645718 1.408 NM_016953
PDE11A
phosphodiesterase 11A
chr9_-_116920232 1.377 NM_002160
TNC
tenascin C
chr14_-_22658078 1.341 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr17_+_55269974 1.333


chr1_+_158636987 1.239 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr20_+_29790564 1.232 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr2_+_33554824 1.199 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_+_17622319 1.195 NM_001159495
BANF2
barrier to autointegration factor 2
chr1_-_27565923 1.193 NM_004672
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr10_-_21847126 1.178


chr12_+_12829807 1.163 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr13_+_109932934 1.131 COL4A2
collagen, type IV, alpha 2
chr1_+_68070573 1.127


chr19_+_45194782 1.126 NM_178544
ZNF546
zinc finger protein 546
chr12_+_115455579 1.109 NCRNA00173
non-protein coding RNA 173
chr3_+_114414064 1.105 NM_033254
BOC
Boc homolog (mouse)
chr4_+_130236731 1.093 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr14_-_93988838 1.082 NM_001080451
SERPINA11
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr7_-_27158726 1.080


chr12_-_47532171 1.076 NM_004818
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr20_+_35406497 1.055 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr2_+_172252473 1.051 DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr15_-_43280664 1.047 NM_138356
SHF
Src homology 2 domain containing F
chr17_+_36515166 1.028 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr6_+_130381408 1.014 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr11_-_119504726 1.012 TRIM29
tripartite motif containing 29
chr10_-_95231933 0.993 NM_013451
NM_133337
MYOF

myoferlin

chr14_+_95792299 0.989 NM_000710
BDKRB1
bradykinin receptor B1
chr16_-_69030421 0.980 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr10_-_116382089 0.944 ABLIM1
actin binding LIM protein 1
chr14_+_23175383 0.931 NM_005794
NM_182908
DHRS2

dehydrogenase/reductase (SDR family) member 2

chr19_-_49552638 0.929 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr3_-_48516486 0.927 NM_016479
SHISA5
shisa homolog 5 (Xenopus laevis)
chr2_-_151052391 0.919 NM_005168
RND3
Rho family GTPase 3
chr2_+_43854681 0.910 NM_001193464
NM_015522
NM_016008
DYNC2LI1


dynein, cytoplasmic 2, light intermediate chain 1


chr14_+_67069668 0.909 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr7_-_5429702 0.906 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr14_-_22468393 0.897 PRMT5
protein arginine methyltransferase 5
chr16_+_19329557 0.895 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr19_-_54258935 0.895 NM_006179
NTF4
neurotrophin 4
chr20_-_47963682 0.894 NM_001135773
SPATA2
spermatogenesis associated 2
chr19_-_41711009 0.892 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr11_+_4522993 0.879 NM_001004137
OR52M1
olfactory receptor, family 52, subfamily M, member 1
chr17_-_51155073 0.862 NM_018286
TMEM100
transmembrane protein 100
chr14_+_31100330 0.856 NM_025152
NUBPL
nucleotide binding protein-like
chr14_-_22722658 0.848 SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr14_+_52243645 0.844 NM_002806
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr2_-_40532651 0.839 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr14_+_20608179 0.828 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr16_-_30705707 0.827 NM_001080417
ZNF629
zinc finger protein 629
chr8_-_130868315 0.827 NM_031415
GSDMC
gasdermin C
chr4_-_140696740 0.821 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr3_+_173043832 0.801 NM_001164436
TMEM212
transmembrane protein 212
chr6_+_84799969 0.798 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr14_-_52487022 0.789 FERMT2
fermitin family member 2
chr11_-_118693021 0.783 NM_006500
MCAM
melanoma cell adhesion molecule
chr17_-_36719030 0.783 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr20_-_42249146 0.781 JPH2
junctophilin 2
chr9_+_116943917 0.780 NM_017418
DEC1
deleted in esophageal cancer 1
chr20_+_5679032 0.776 NM_152504
C20orf196
chromosome 20 open reading frame 196
chr14_-_24588916 0.776 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr8_+_70567634 0.761 SULF1
sulfatase 1
chr3_-_150422474 0.755 NM_000096
CP
ceruloplasmin (ferroxidase)
chr12_+_51730101 0.754 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr17_-_36915329 0.753 NM_002274
NM_153490
KRT13

keratin 13

chr19_+_17440577 0.750 SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr2_+_159533329 0.745 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr19_+_49361054 0.743 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr11_+_118259684 0.740 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr19_+_15079141 0.739 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr1_-_143706300 0.736 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr12_-_68369322 0.727 NM_152439
BEST3
bestrophin 3
chr6_-_45453552 0.726 NM_003599
NM_181356
SUPT3H

suppressor of Ty 3 homolog (S. cerevisiae)

chr2_-_128000315 0.724 NM_017969
IWS1
IWS1 homolog (S. cerevisiae)
chr4_-_122063118 0.722 NM_018699
PRDM5
PR domain containing 5
chr2_-_142605739 0.722 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr9_+_103200939 0.721 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr10_+_88718167 0.716 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr14_-_22722680 0.700 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr17_+_29606408 0.700 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr12_+_52713098 0.693 NM_018953
HOXC5
homeobox C5
chr10_-_62163083 0.689 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_151854619 0.686 NM_004688
NMI
N-myc (and STAT) interactor
chr1_+_40769819 0.685 NM_152373
ZNF684
zinc finger protein 684
chr15_+_89212888 0.682 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr14_+_31868229 0.681 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr16_+_65761905 0.675 NM_001185058
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr20_+_51023159 0.674 TSHZ2
teashirt zinc finger homeobox 2
chr16_+_10945815 0.673 NM_015226
CLEC16A
C-type lectin domain family 16, member A
chr6_-_29081015 0.672 NM_001010877
ZNF311
zinc finger protein 311
chr14_-_22468445 0.672 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr1_-_116184846 0.672 NM_001111061
NHLH2
nescient helix loop helix 2
chr11_-_85115105 0.670 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr1_+_36462625 0.670 THRAP3
thyroid hormone receptor associated protein 3
chr6_+_26312758 0.667 NM_003545
HIST1H4E
histone cluster 1, H4e
chr3_+_184453547 0.664 NM_032047
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr20_+_17628592 0.663 NM_001014977
NM_178477
BANF2

barrier to autointegration factor 2

chr6_-_31797434 0.662 NM_025261
LY6G6C
lymphocyte antigen 6 complex, locus G6C
chr9_-_129729518 0.662 NM_173492
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr5_-_180563945 0.661 NM_203294
NM_203295
NM_203296
TRIM7


tripartite motif containing 7


chr14_-_22693333 0.660 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr3_+_137224266 0.659 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr7_-_87774130 0.658 NM_024636
STEAP4
STEAP family member 4
chr18_+_3437607 0.652 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr2_-_61551350 0.651 NM_014709
USP34
ubiquitin specific peptidase 34
chr1_+_40769877 0.649 ZNF684
zinc finger protein 684
chr14_+_23855291 0.649 LTB4R
leukotriene B4 receptor
chr17_-_38979178 0.644 NM_001079675
ETV4
ets variant 4
chr14_-_22516271 0.642 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr16_-_18709125 0.641 NM_001019
NM_001030009
RPS15A

ribosomal protein S15a

chr11_+_36572615 0.641 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr20_+_54637714 0.639 NM_003222
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr14_+_19881552 0.638 NM_001042618
NM_005484
PARP2

poly (ADP-ribose) polymerase 2

chr2_-_142605010 0.634 LRP1B
low density lipoprotein receptor-related protein 1B
chr1_-_149404954 0.629 NM_212551
NM_001136543
LYSMD1

LysM, putative peptidoglycan-binding, domain containing 1

chr12_-_41164010 0.626 PRICKLE1
prickle homolog 1 (Drosophila)
chr12_-_41164052 0.622 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr5_+_40877053 0.618 NM_032587
CARD6
caspase recruitment domain family, member 6
chr21_-_34749908 0.617 NM_001127670
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr1_-_143706265 0.613 PDE4DIP
phosphodiesterase 4D interacting protein
chr12_+_13088412 0.612 KIAA1467
KIAA1467
chr20_+_57948803 0.612 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr11_-_86061301 0.611 NM_001161586
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr1_+_32485404 0.610 NM_032648
FAM167B
family with sequence similarity 167, member B
chr16_-_73842884 0.598 NM_001170717
NM_014567
BCAR1

breast cancer anti-estrogen resistance 1

chr3_+_189353502 0.597 LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_143706196 0.596 PDE4DIP
phosphodiesterase 4D interacting protein
chr8_+_70567581 0.595 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr7_+_138469029 0.595 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr17_+_11864841 0.594 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr14_+_22305570 0.594 NM_005015
OXA1L
oxidase (cytochrome c) assembly 1-like
chr16_-_15644465 0.593 NM_001184998
NM_001184999
NM_014647
KIAA0430


KIAA0430


chr9_-_116305273 0.590 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr12_+_67366989 0.590 NM_020401
NUP107
nucleoporin 107kDa
chr15_+_56217686 0.577 NM_020980
AQP9
aquaporin 9
chr16_+_2461500 0.575 NM_006181
NTN3
netrin 3
chr20_+_5935897 0.574 NM_001127458
CRLS1
cardiolipin synthase 1
chr10_+_75343352 0.569 PLAU
plasminogen activator, urokinase
chr19_+_49309350 0.569 NM_013362
ZNF225
zinc finger protein 225
chr8_-_10550026 0.567 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr12_-_642786 0.565 NM_016533
NINJ2
ninjurin 2
chr15_-_81412354 0.565 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr2_+_108360798 0.565 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr2_+_135526304 0.564 NM_001172435
NM_012233
RAB3GAP1

RAB3 GTPase activating protein subunit 1 (catalytic)

chr18_-_26876622 0.562 NM_001941
NM_024423
DSC3

desmocollin 3

chr2_-_55500450 0.562 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr1_-_225572419 0.560 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chr2_-_148494732 0.560 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr2_-_56266408 0.559 LOC100129434
hypothetical LOC100129434
chr3_+_50204026 0.559 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr3_-_131948202 0.546 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr16_+_15644624 0.545 NM_001143979
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr17_+_64922420 0.541 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr16_+_88515917 0.540 NM_001197181
TUBB3
tubulin, beta 3
chr19_-_49131250 0.539 NM_003425
ZNF45
zinc finger protein 45
chr14_+_23700261 0.534 NM_006084
IRF9
interferon regulatory factor 9
chr2_+_32244406 0.533 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr2_+_27740254 0.533 SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr4_-_152901542 0.532 NM_004564
PET112L
PET112-like (yeast)
chr1_-_151788341 0.531 NM_002960
S100A3
S100 calcium binding protein A3
chr11_-_57173823 0.524 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr20_-_20641122 0.524 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr20_-_14266200 0.523 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr3_-_126576693 0.523 NM_021964
ZNF148
zinc finger protein 148
chr1_-_166372244 0.521 NM_153832
GPR161
G protein-coupled receptor 161
chr6_+_46728590 0.521 NM_004277
SLC25A27
solute carrier family 25, member 27
chr2_-_227952249 0.521 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr19_-_47438583 0.520 GSK3A
glycogen synthase kinase 3 alpha
chr14_-_29466562 0.519 NM_002742
PRKD1
protein kinase D1
chr12_+_8866416 0.519 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr8_-_127639892 0.518 NM_174911
FAM84B
family with sequence similarity 84, member B
chr5_+_148631588 0.515 NM_001146337
NM_152406
AFAP1L1

actin filament associated protein 1-like 1

chr11_+_117680504 0.512 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr6_-_116973465 0.511 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr6_+_31648071 0.511 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr2_+_174907914 0.510 NM_001145250
SP9
Sp9 transcription factor homolog (mouse)
chr22_-_37966852 0.505 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr6_-_42218692 0.501 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr17_-_36528113 0.501 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr6_-_35572694 0.500 NM_003214
TEAD3
TEA domain family member 3
chr5_+_148631636 0.500 AFAP1L1
actin filament associated protein 1-like 1
chr6_-_36463320 0.499 NM_016135
ETV7
ets variant 7
chr19_+_59973074 0.498 NM_014218
KIR2DS2
KIR2DL1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr2_+_113016236 0.496 POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr17_-_36760581 0.493 NM_004138
KRT33A
keratin 33A
chr6_-_46997579 0.492 NM_001098518
GPR116
G protein-coupled receptor 116
chr20_-_33580861 0.492 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr6_-_34632061 0.490 NM_012391
SPDEF
SAM pointed domain containing ets transcription factor
chr9_+_22103542 0.488 CDKN2B-AS1
CDKN2B antisense RNA 1 (non-protein coding)
chr9_-_131555111 0.485 NM_004878
PTGES
prostaglandin E synthase
chr7_-_22363036 0.484 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.