Motif ID: TBX4,5.p2

Z-value: 1.480


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5



Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_26609893 1.777 LIN28A
lin-28 homolog A (C. elegans)
chr1_+_43661383 1.579 NM_015284
KIAA0467
KIAA0467
chr1_+_26609819 1.429 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr9_-_34387786 0.993 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr18_+_30810889 0.971 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_-_66218777 0.943 EPHA5
EPH receptor A5
chr4_+_8633116 0.934 NM_080819
GPR78
G protein-coupled receptor 78
chr11_-_72063059 0.925 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr3_+_26639300 0.905 NM_052953
LRRC3B
leucine rich repeat containing 3B
chr3_+_129690735 0.893


chr1_-_47468029 0.875 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr12_-_56312696 0.846 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr20_+_8060762 0.809 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr2_-_133144094 0.787 LYPD1
LY6/PLAUR domain containing 1
chr2_+_176761552 0.779 NM_024501
HOXD1
homeobox D1
chr3_-_173648896 0.769 NM_004122
NM_198407
GHSR

growth hormone secretagogue receptor

chr19_-_51829778 0.765 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr3_+_12020803 0.756 NM_003178
NM_133625
SYN2

synapsin II

chrX_-_142551587 0.753 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr12_-_3472245 0.748 LOC100129223
hypothetical LOC100129223
chr8_+_56177567 0.741 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr16_+_88517187 0.713 NM_006086
TUBB3
tubulin, beta 3
chr4_-_108176901 0.708 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr22_-_31732648 0.708 NM_003490
NM_133633
SYN3

synapsin III

chr5_-_114543632 0.703 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr3_-_135231518 0.702 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr17_-_10682123 0.702 NM_001101387
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr2_+_171280182 0.698


chr3_-_135231417 0.693 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr3_+_127596471 0.692 NM_182628
CCDC37
coiled-coil domain containing 37
chr13_+_34414390 0.689 NM_015678
NBEA
neurobeachin
chr22_+_23153529 0.685 NM_000675
ADORA2A
adenosine A2a receptor
chr7_+_70235724 0.681 NM_022479
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr15_+_77362200 0.679 NM_001146341
ANKRD34C
ankyrin repeat domain 34C
chr4_-_66218247 0.677 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr2_+_171280046 0.674 NM_001003845
SP5
Sp5 transcription factor
chr12_-_6626858 0.671 ACRBP
acrosin binding protein
chr12_-_116021473 0.666 NM_001168325
NM_017899
TESC

tescalcin

chr15_-_71830868 0.664 NM_001039614
C15orf59
chromosome 15 open reading frame 59
chr19_+_55398680 0.658 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr4_+_155884600 0.652 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr1_+_157441133 0.650 NM_002036
DARC
Duffy blood group, chemokine receptor
chr17_+_56888588 0.649 NM_018488
TBX4
T-box 4
chr11_+_61204392 0.637 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr6_-_71069347 0.630 NM_001851
COL9A1
collagen, type IX, alpha 1
chr9_-_103237851 0.630 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr2_+_74594093 0.625 TLX2
T-cell leukemia homeobox 2
chr15_+_72209039 0.608 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_-_123460722 0.603 NM_001136002
TMEM229A
transmembrane protein 229A
chr13_+_99432258 0.596 NM_007129
ZIC2
Zic family member 2 (odd-paired homolog, Drosophila)
chr11_+_26310253 0.594 NM_031418
ANO3
anoctamin 3
chr16_-_1410710 0.589 C16orf91
chromosome 16 open reading frame 91
chr1_+_183970093 0.584 NM_031935
HMCN1
hemicentin 1
chr12_-_70952410 0.583 LOC283392
hypothetical LOC283392
chr5_+_71438796 0.582 NM_005909
MAP1B
microtubule-associated protein 1B
chr7_-_155019299 0.578 NM_001103176
CNPY1
canopy 1 homolog (zebrafish)
chr22_+_25383392 0.577 MIAT
myocardial infarction associated transcript (non-protein coding)
chr19_+_45794895 0.574 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr9_+_139152595 0.569 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr12_+_70952729 0.568 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr9_+_128416542 0.567 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chrX_-_107866262 0.566 NM_003604
IRS4
insulin receptor substrate 4
chr4_+_156900053 0.558 GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr5_+_113726203 0.557 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr15_+_72208751 0.551 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_-_3620060 0.551 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr19_+_10261646 0.548 NM_003259
ICAM5
intercellular adhesion molecule 5, telencephalin
chr19_+_810673 0.543 CFD
complement factor D (adipsin)
chr1_-_20122638 0.540 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr12_-_70952572 0.537 LOC283392
hypothetical LOC283392
chr11_-_2108035 0.536 IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_-_48578878 0.529 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr6_+_127481740 0.527 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr3_+_19164973 0.526 NM_144633
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr1_-_36721501 0.523 NM_000760
NM_156039
NM_172313
CSF3R


colony stimulating factor 3 receptor (granulocyte)


chr5_-_44424423 0.522 NM_004465
FGF10
fibroblast growth factor 10
chr12_+_130004404 0.520 NM_198827
GPR133
G protein-coupled receptor 133
chr11_-_118739838 0.518 USP2
ubiquitin specific peptidase 2
chr5_-_134899537 0.517 NM_006161
NEUROG1
neurogenin 1
chr8_+_21968273 0.516 NM_001114136
NM_001114139
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr11_+_61279436 0.514 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr15_-_93671314 0.513 LOC400456
hypothetical LOC400456
chr9_+_136912474 0.513 NM_004108
NM_015837
FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

chrX_-_114374860 0.507 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr2_+_171280944 0.506 SP5
Sp5 transcription factor
chr5_-_177355848 0.499 NM_006261
PROP1
PROP paired-like homeobox 1
chr16_+_88512769 0.498 MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr11_-_103539895 0.496 PDGFD
platelet derived growth factor D
chr6_-_32121784 0.495 NM_032470
TNXB
tenascin XB
chr9_-_72926333 0.491 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr11_-_114880275 0.487 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr12_-_60872814 0.484 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr7_-_150604752 0.482 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr21_-_41801778 0.480 NM_001135099
TMPRSS2
transmembrane protease, serine 2
chr22_-_27405708 0.475 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr8_+_21968375 0.472 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr8_+_99508425 0.471 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr19_+_40325993 0.471 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr12_+_77782925 0.462 SYT1
synaptotagmin I
chr9_+_123501186 0.458 DAB2IP
DAB2 interacting protein
chr5_-_83715947 0.457 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr14_-_91403609 0.453 NM_001128596
TC2N
tandem C2 domains, nuclear
chr1_+_34415139 0.449 NM_001134734
C1orf94
chromosome 1 open reading frame 94
chr19_-_4468715 0.447 NM_001080400
PLIN4
perilipin 4
chr1_+_17121012 0.446 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr6_-_40003295 0.445 NM_005943
MOCS1
molybdenum cofactor synthesis 1
chr4_-_149582754 0.443 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr19_+_55571493 0.441 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr11_+_122214415 0.441 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr15_+_81567327 0.441 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr4_-_165523856 0.435 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr5_+_71050745 0.434 NM_004291
CARTPT
CART prepropeptide
chr19_+_51059357 0.433 NM_004497
FOXA3
forkhead box A3
chr7_-_36992221 0.431 NM_130442
ELMO1
engulfment and cell motility 1
chr11_+_131286513 0.430 NTM
neurotrimin
chr11_+_48303047 0.426 NM_001004702
OR4C3
olfactory receptor, family 4, subfamily C, member 3
chr11_-_2138984 0.426 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr19_-_54557450 0.425 NM_003598
TEAD2
TEA domain family member 2
chr5_-_132194122 0.424


chr19_+_810658 0.420 NM_001928
CFD
complement factor D (adipsin)
chr18_+_58143499 0.420 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chrX_+_101853912 0.420 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr17_-_33178987 0.419 HNF1B
HNF1 homeobox B
chr12_+_117903682 0.418 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr5_+_113725914 0.415 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr17_-_30440351 0.415 NM_057178
RFFL
ring finger and FYVE-like domain containing 1
chr18_-_45975163 0.413 NM_001080467
MYO5B
myosin VB
chr17_+_31562577 0.411 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr5_-_88016397 0.408 LOC645323
hypothetical LOC645323
chr13_+_112704077 0.407 MCF2L
MCF.2 cell line derived transforming sequence-like
chr3_-_51971915 0.406 NM_033010
PCBP4
poly(rC) binding protein 4
chr1_-_11830328 0.404 NM_006172
NPPA
natriuretic peptide A
chr3_-_184756101 0.403 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr8_+_144428083 0.402 GLI4
GLI family zinc finger 4
chr2_+_74595073 0.400 NM_016170
TLX2
T-cell leukemia homeobox 2
chr17_+_22823151 0.399 NM_014238
KSR1
kinase suppressor of ras 1
chr9_-_138757175 0.395 NM_001001712
LCN10
lipocalin 10
chr17_-_28644118 0.395 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr4_+_3285671 0.393 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr5_-_172688024 0.391 STC2
stanniocalcin 2
chrX_+_101887562 0.386 NM_001142529
NM_001142530
BHLHB9

basic helix-loop-helix domain containing, class B, 9

chr3_+_134239906 0.386 TMEM108
transmembrane protein 108
chr21_-_44784499 0.385 NM_198691
KRTAP10-1
keratin associated protein 10-1
chr1_-_175400441 0.385 ASTN1
astrotactin 1
chr12_-_43556220 0.382 NELL2
NEL-like 2 (chicken)
chr7_-_124192916 0.381 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr17_+_65612589 0.379 NM_170742
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_202595666 0.377 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr12_-_56312879 0.377 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr3_+_134239860 0.377 NM_001136469
NM_023943
TMEM108

transmembrane protein 108

chr13_-_99983945 0.376 NM_033110
A2LD1
AIG2-like domain 1
chr21_-_44824907 0.375 NM_198694
KRTAP10-5
keratin associated protein 10-5
chrX_+_122145776 0.375 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr1_+_166516901 0.374 NM_005149
TBX19
T-box 19
chr4_+_114433551 0.374 ANK2
ankyrin 2, neuronal
chr4_+_91035025 0.374 NM_007351
MMRN1
multimerin 1
chr11_-_63138061 0.371 PLA2G16
phospholipase A2, group XVI
chr22_-_28992787 0.370 NM_020530
OSM
oncostatin M
chr22_+_38213174 0.370 NM_001098270
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr5_-_134942867 0.369 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr2_+_176680251 0.368 NM_021192
HOXD11
homeobox D11
chr6_-_32184975 0.367 NM_019105
TNXB
tenascin XB
chr12_-_6626794 0.366 NM_032489
ACRBP
acrosin binding protein
chr20_-_1113116 0.365 NM_018354
C20orf46
chromosome 20 open reading frame 46
chrX_+_101792949 0.364 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr1_+_17719405 0.363 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr9_+_70107602 0.362 NM_199135
FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr3_+_135996990 0.362 EPHB1
EPH receptor B1
chr19_+_15765760 0.360 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr19_+_10242763 0.359 ICAM1
intercellular adhesion molecule 1
chr3_-_129690056 0.358 NM_001145661
GATA2
GATA binding protein 2
chr8_-_142446546 0.357 NM_005293
GPR20
G protein-coupled receptor 20
chr19_-_44386731 0.357 NM_001080468
SYCN
syncollin
chr6_+_97479216 0.355 NM_052904
KLHL32
kelch-like 32 (Drosophila)
chr13_+_112704028 0.354 MCF2L
MCF.2 cell line derived transforming sequence-like
chr9_-_115877104 0.353 AMBP
alpha-1-microglobulin/bikunin precursor
chr15_+_41879912 0.353 NM_016400
C15orf63
chromosome 15 open reading frame 63
chr5_-_132194488 0.352 NM_001172700
SHROOM1
shroom family member 1
chr14_-_60185659 0.349 NM_005982
SIX1
SIX homeobox 1
chr2_+_170298487 0.348


chr13_+_112704051 0.347 MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_+_36531059 0.345 NM_005318
H1F0
H1 histone family, member 0
chr12_-_43556338 0.344 NELL2
NEL-like 2 (chicken)
chr11_+_129190942 0.344 NM_138788
TMEM45B
transmembrane protein 45B
chr1_-_92721943 0.342 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr19_+_40716153 0.342 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr13_-_19244398 0.341 PSPC1
paraspeckle component 1
chr17_-_37222349 0.341 LEPREL4
leprecan-like 4
chr8_-_22606401 0.340 EGR3
early growth response 3
chr22_-_49363711 0.340 NM_004377
NM_152246
NM_001145134
NM_001145135
NM_001145136
NM_152245
CPT1B





carnitine palmitoyltransferase 1B (muscle)





chr18_+_75760434 0.340


chr10_-_102978678 0.339 NM_006562
LBX1
ladybird homeobox 1
chr11_+_125279481 0.337 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr1_+_53300410 0.336 NM_153703
PODN
podocan
chr9_+_33740463 0.333 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr19_+_53559468 0.333 NM_012451
SYNGR4
synaptogyrin 4
chr3_+_52254782 0.330 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr21_-_41801946 0.330 TMPRSS2
transmembrane protease, serine 2
chr1_+_6226838 0.329 NM_001024598
HES3
hairy and enhancer of split 3 (Drosophila)
chr11_+_6237541 0.327 NM_176875
CCKBR
cholecystokinin B receptor

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.