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• Activity deltas table
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Motif ID: TCF4_dimer.p2

Z-value: 2.135

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_20068039	3.455	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr11_+_70926718	3.452	NM_021046	KRTAP5-8	keratin associated protein 5-8
chr22_-_20235372	3.400	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr7_-_130891861	3.029	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr2_+_85834111	2.616	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr9_-_96441409	2.429		FBP1	fructose-1,6-bisphosphatase 1
chr17_+_36493927	2.399	NM_033061	KRTAP4-7	keratin associated protein 4-7
chr15_+_81567327	2.247	NM_001144903 NM_023003	TM6SF1	transmembrane 6 superfamily member 1
chr15_-_53822468	2.140	NM_173814	PRTG	protogenin
chr2_-_241484245	2.054	NM_001085437	C2orf54	chromosome 2 open reading frame 54
chr13_+_30378311	1.985	NM_032849	C13orf33	chromosome 13 open reading frame 33
chr9_-_96441654	1.858	NM_000507	FBP1	fructose-1,6-bisphosphatase 1
chr8_+_37773991	1.788		GPR124	G protein-coupled receptor 124
chr17_-_36594652	1.785	NM_033060	KRTAP4-1	keratin associated protein 4-1
chr17_+_4348877	1.735	NM_001124758	SPNS2	spinster homolog 2 (Drosophila)
chr19_+_43446937	1.710	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr12_-_89873081	1.703	NM_152638	C12orf12	chromosome 12 open reading frame 12
chr16_-_73798539	1.686	NM_001025200	CTRB1 CTRB2	chymotrypsinogen B1 chymotrypsinogen B2
chr15_-_42274529	1.670	NM_032892	FRMD5	FERM domain containing 5
chr16_-_87570716	1.666	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_-_50573759	1.644	NM_020717	SHROOM4	shroom family member 4
chr14_+_76298693	1.640		VASH1	vasohibin 1
chr21_+_36429079	1.609	NM_001236	CBR3	carbonyl reductase 3
chr19_+_43447078	1.609		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr19_+_43447262	1.604		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr2_-_241270982	1.574	NM_001102467	AQP12A AQP12B	aquaporin 12A aquaporin 12B
chr6_+_96570565	1.563	NM_006581	FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr1_-_27211913	1.508	NM_052943	FAM46B	family with sequence similarity 46, member B
chr11_+_113436438	1.498	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr6_+_18495559	1.497	NM_182757	RNF144B	ring finger protein 144B
chr1_-_40140126	1.485	NM_001033081 NM_001033082 NM_005376	MYCL1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr8_-_143692814	1.482	NM_015193	ARC	activity-regulated cytoskeleton-associated protein
chr2_+_33213111	1.435	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr15_-_42274760	1.406		FRMD5	FERM domain containing 5
chrX_-_13866366	1.388
chr22_+_19660361	1.367		AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr2_+_241279934	1.364	NM_198998	AQP12A AQP12B	aquaporin 12A aquaporin 12B
chr9_-_96441567	1.363		FBP1	fructose-1,6-bisphosphatase 1
chr17_-_7106987	1.349	NM_001185023 NM_001307	CLDN7	claudin 7
chr7_-_143731718	1.326	NM_001080413	NOBOX	NOBOX oogenesis homeobox
chr17_+_36515166	1.305	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr11_+_76516957	1.292	NM_000260 NM_001127179 NM_001127180	MYO7A	myosin VIIA
chr5_-_159672060	1.274	NM_024565	CCNJL	cyclin J-like
chr11_-_6298284	1.268	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chrX_+_110074124	1.264	NM_001128166 NM_001128167	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chrX_-_128616594	1.264	NM_017413	APLN	apelin
chr17_+_45008175	1.261	NM_007225	NXPH3	neurexophilin 3
chr15_+_55455994	1.251	NM_032866	CGNL1	cingulin-like 1
chr19_+_18655487	1.247		CRTC1	CREB regulated transcription coactivator 1
chr17_-_36507900	1.229	NM_031960	KRTAP4-8	keratin associated protein 4-8
chr2_+_27358800	1.222	NM_032546 NM_187841	TRIM54	tripartite motif containing 54
chrX_-_106905545	1.221		TSC22D3	TSC22 domain family, member 3
chr22_-_37858871	1.203		CBX7	chromobox homolog 7
chr19_-_61874934	1.201		ZNF835	zinc finger protein 835
chr21_+_46355797	1.196		COL6A2	collagen, type VI, alpha 2
chrX_+_100361588	1.193	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr9_+_37640996	1.176	NM_014907	FRMPD1	FERM and PDZ domain containing 1
chr2_+_109112428	1.159	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr1_+_181259317	1.154
chr11_+_70915960	1.153	NM_001012503	KRTAP5-7	keratin associated protein 5-7
chr16_+_56230707	1.153	NM_001145774	GPR56	G protein-coupled receptor 56
chr19_-_60587414	1.146	NM_001190764	LOC388564	hypothetical protein LOC388564
chr17_-_24077246	1.136	NM_138463	TLCD1	TLC domain containing 1
chr16_+_68765428	1.132	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr1_+_100776280	1.129	NM_022049	GPR88	G protein-coupled receptor 88
chr6_-_39398293	1.128	NM_001135105 NM_001135106 NM_001135107 NM_032115	KCNK16	potassium channel, subfamily K, member 16
chr8_-_145609737	1.125		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr19_+_40224480	1.120		HPN	hepsin
chr19_-_56229808	1.118	NM_019598 NM_145894 NM_145895	KLK12	kallikrein-related peptidase 12
chr7_-_28186867	1.118	NM_175061	JAZF1	JAZF zinc finger 1
chr19_+_14405216	1.117		PKN1	protein kinase N1
chr5_-_136862130	1.111		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr17_-_39700960	1.110	NM_000342	SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr20_+_29870836	1.109	NM_033118	MYLK2	myosin light chain kinase 2
chr15_-_58671929	1.098	NM_134262	RORA	RAR-related orphan receptor A
chr16_-_15742883	1.095		MYH11	myosin, heavy chain 11, smooth muscle
chr9_-_135379888	1.084	NM_001080483	TMEM8C	transmembrane protein 8C
chr16_+_68542310	1.080	NM_182619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr17_+_36599664	1.076	NM_001190460	KRTAP9-1	keratin associated protein 9-1
chr17_+_37694007	1.068		STAT5A	signal transducer and activator of transcription 5A
chr15_-_49184764	1.067	NM_207381	TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr1_+_24614831	1.066	NM_020448	NIPAL3	NIPA-like domain containing 3
chr11_+_1816808	1.065	NM_003282	TNNI2	troponin I type 2 (skeletal, fast)
chr6_-_31188310	1.064	NM_014070	C6orf15	chromosome 6 open reading frame 15
chr8_-_139578246	1.055	NM_015912	FAM135B	family with sequence similarity 135, member B
chr7_+_116099648	1.048	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chrX_-_13866451	1.043		GPM6B	glycoprotein M6B
chr5_+_169465478	1.036	NM_012188 NM_144769	FOXI1	forkhead box I1
chrX_-_106905657	1.031	NM_198057	TSC22D3	TSC22 domain family, member 3
chrX_+_48221323	1.030	NM_177434	FTSJ1	FtsJ homolog 1 (E. coli)
chr1_+_199975271	1.030		NAV1	neuron navigator 1
chr17_-_36559579	1.026	NM_033188	KRTAP4-5	keratin associated protein 4-5
chr1_-_39871226	1.022		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr11_+_61204392	1.015	NM_006133	DAGLA	diacylglycerol lipase, alpha
chr12_+_108690199	1.015		C12orf34	chromosome 12 open reading frame 34
chr15_-_88143721	1.013		ANPEP	alanyl (membrane) aminopeptidase
chr1_-_27212035	1.013		FAM46B	family with sequence similarity 46, member B
chr6_-_31977747	1.009	NM_181842	ZBTB12	zinc finger and BTB domain containing 12
chr1_-_6585268	1.003		KLHL21	kelch-like 21 (Drosophila)
chr19_-_51829778	1.002	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr9_+_135389698	0.995	NM_014694	ADAMTSL2	ADAMTS-like 2
chr17_+_26060617	0.986
chr14_-_105948734	0.978		LOC100126583 IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG4 IGHM	hypothetical LOC100126583 immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 4 (G4m marker) immunoglobulin heavy constant mu
chr7_-_120285245	0.975		TSPAN12	tetraspanin 12
chr5_+_66160359	0.969	NM_015183	MAST4	microtubule associated serine/threonine kinase family member 4
chr4_+_151218862	0.960	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr7_-_135083906	0.957	NM_205855	FAM180A	family with sequence similarity 180, member A
chr15_-_72981595	0.953		C15orf17	chromosome 15 open reading frame 17
chr11_-_16992524	0.951	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr11_-_684842	0.950		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr3_+_32255215	0.946		CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr2_+_233099113	0.944	NM_000751	CHRND	cholinergic receptor, nicotinic, delta
chr12_+_47498778	0.942	NM_000725	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr1_+_201364050	0.936		ADORA1	adenosine A1 receptor
chr6_+_36754467	0.935		CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr3_+_32255158	0.929	NM_178868	CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr2_+_176761552	0.926	NM_024501	HOXD1	homeobox D1
chr17_+_36636404	0.923	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr19_+_40224457	0.915		HPN	hepsin
chr12_+_129388543	0.910		PIWIL1	piwi-like 1 (Drosophila)
chr11_+_817584	0.905	NM_173584	EFCAB4A	EF-hand calcium binding domain 4A
chr6_+_7672009	0.899	NM_001718	BMP6	bone morphogenetic protein 6
chr16_+_87232501	0.899	NM_013278	IL17C	interleukin 17C
chr2_+_128119908	0.892	NM_001161415 NM_001161416 NM_001161417 NM_005291	GPR17	G protein-coupled receptor 17
chr3_+_141879555	0.890	NM_152616	TRIM42	tripartite motif containing 42
chr22_-_30071761	0.886		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr2_-_101134146	0.879	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr14_+_76297885	0.878	NM_014909	VASH1	vasohibin 1
chr8_-_131483395	0.877	NM_018482	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr16_-_73012740	0.876	NM_001011880	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr9_-_129869211	0.875	NM_197956	NAIF1	nuclear apoptosis inducing factor 1
chr9_+_123544884	0.874	NM_138709	DAB2IP	DAB2 interacting protein
chr22_+_29122932	0.872	NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr5_-_136862317	0.871		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr17_+_36665161	0.867	NM_030975	KRTAP9-9	keratin associated protein 9-9
chr12_+_103675075	0.861		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr2_-_80384454	0.859		LRRTM1	leucine rich repeat transmembrane neuronal 1
chr17_-_7106497	0.858		CLDN7	claudin 7
chr11_-_65070625	0.858		LTBP3	latent transforming growth factor beta binding protein 3
chr11_-_1026654	0.856	NM_005961	MUC6	mucin 6, oligomeric mucus/gel-forming
chr5_+_71438796	0.852	NM_005909	MAP1B	microtubule-associated protein 1B
chr5_+_1254709	0.852	NM_001003841	SLC6A19	solute carrier family 6 (neutral amino acid transporter), member 19
chr15_-_23659329	0.851	NM_024490	ATP10A	ATPase, class V, type 10A
chr5_+_159276317	0.846	NM_000679	ADRA1B	adrenergic, alpha-1B-, receptor
chr5_+_143171918	0.844	NM_021182	HMHB1	histocompatibility (minor) HB-1
chr19_+_18655483	0.835		CRTC1	CREB regulated transcription coactivator 1
chr10_-_61819493	0.834	NM_020987	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr16_+_972064	0.829		SOX8	SRY (sex determining region Y)-box 8
chr20_+_42007949	0.825	NM_001098798	TOX2	TOX high mobility group box family member 2
chr13_+_112789669	0.820		MCF2L	MCF.2 cell line derived transforming sequence-like
chr6_+_138524717	0.819	NM_020340	KIAA1244	KIAA1244
chr1_+_199975674	0.816		NAV1	neuron navigator 1
chr22_-_36212160	0.813	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_-_70220605	0.811	NM_139018	CD300LF	CD300 molecule-like family member f
chrX_+_69559605	0.810	NM_001171191 NM_001171192 NM_001171193 NM_017711	GDPD2	glycerophosphodiester phosphodiesterase domain containing 2
chr16_+_971808	0.808	NM_014587	SOX8	SRY (sex determining region Y)-box 8
chr19_-_59495949	0.805	NM_001172654 NM_006865	LILRB2 LILRA3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr10_-_21847126	0.805
chr12_+_6819635	0.802	NM_002075	GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3
chr22_+_18081968	0.802	NM_002688	SEPT5	septin 5
chr1_+_18680010	0.798	NM_152375	KLHDC7A	kelch domain containing 7A
chr2_+_56265260	0.798
chr1_+_242281175	0.792	NM_205768	ZNF238	zinc finger protein 238
chr6_+_167658563	0.791	NM_031949	TTLL2	tubulin tyrosine ligase-like family, member 2
chr2_-_183439515	0.785	NM_001463	FRZB	frizzled-related protein
chr4_-_191143017	0.784	NM_020040	TUBB4Q	tubulin, beta polypeptide 4, member Q
chr14_-_105851580	0.778		IGHA1 IGHA2 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_6473759	0.777		RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_+_70438352	0.776	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr19_+_51498695	0.776	NM_152794	HIF3A	hypoxia inducible factor 3, alpha subunit
chr1_-_23729871	0.774		E2F2	E2F transcription factor 2
chrX_+_53095230	0.770	NM_018969	GPR173	G protein-coupled receptor 173
chr8_+_31010319	0.767	NM_000553	WRN	Werner syndrome, RecQ helicase-like
chr9_-_115101140	0.767	NM_145051	RNF183	ring finger protein 183
chr2_-_216944911	0.764	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr1_+_199975563	0.761	NM_001167738	NAV1	neuron navigator 1
chr12_+_48630790	0.761	NM_000486	AQP2	aquaporin 2 (collecting duct)
chr9_-_130980359	0.761	NM_203434	IER5L	immediate early response 5-like
chr1_+_46418786	0.757		TSPAN1	tetraspanin 1
chr3_+_32123140	0.756		GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr11_+_113435640	0.754	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr9_-_139060285	0.753		NPDC1	neural proliferation, differentiation and control, 1
chr17_+_45488356	0.752		ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_+_45488330	0.752	NM_002204 NM_005501	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr16_-_71549149	0.748		ZFHX3	zinc finger homeobox 3
chr1_+_1104939	0.746	NM_153254	TTLL10	tubulin tyrosine ligase-like family, member 10
chr12_-_68379331	0.745	NM_032735	BEST3	bestrophin 3
chr15_+_66658626	0.738	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr17_+_40192072	0.737	NM_002390	ADAM11	ADAM metallopeptidase domain 11
chr8_-_49996353	0.735	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr5_+_148501178	0.726	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr8_+_145138874	0.725		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr3_-_11598829	0.725	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr10_-_116382089	0.722		ABLIM1	actin binding LIM protein 1
chr19_-_2259155	0.721	NM_001101391	LINGO3	leucine rich repeat and Ig domain containing 3
chr11_-_63689780	0.721		MACROD1	MACRO domain containing 1
chr14_-_105549177	0.717		IGHV4-31 IGHD IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr1_-_24311212	0.712	NM_152372	MYOM3	myomesin family, member 3
chr5_+_55069601	0.711	NM_001142549 NM_001166533 NM_024415	DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr22_-_30071565	0.710		PATZ1	POZ (BTB) and AT hook containing zinc finger 1

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
18.63	8.51e-06	GO:0045095	keratin filament
3.09	1.90e-04	GO:0005856	cytoskeleton
3.61	2.93e-04	GO:0044430	cytoskeletal part
8.93	1.23e-03	GO:0005882	intermediate filament
7.73	3.12e-03	GO:0045111	intermediate filament cytoskeleton
9.43	1.76e-02	GO:0044449	contractile fiber part
13.31	2.15e-02	GO:0016459	myosin complex
8.66	2.62e-02	GO:0043292	contractile fiber

Nothing significant found in function category.