Motif ID: VSX1,2.p2

Z-value: 0.403


Transcription factors associated with VSX1,2.p2:

Gene SymbolEntrez IDGene Name
VSX1 30813 visual system homeobox 1
VSX2 338917 visual system homeobox 2



Activity profile for motif VSX1,2.p2.

activity profile for motif VSX1,2.p2


Sorted Z-values histogram for motif VSX1,2.p2

Sorted Z-values for motif VSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of VSX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_56230953 0.347 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr12_+_28301399 0.338 NM_018318
CCDC91
coiled-coil domain containing 91
chr1_+_100776280 0.325 NM_022049
GPR88
G protein-coupled receptor 88
chr4_+_88790477 0.233 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr20_-_49852353 0.213 NM_020436
SALL4
sal-like 4 (Drosophila)
chr2_+_17861266 0.203 NM_001105569
MSGN1
mesogenin 1
chr10_+_44726635 0.179 NM_001123376
TMEM72
transmembrane protein 72
chr12_-_52016270 0.175 NM_001173467
SP7
Sp7 transcription factor
chrX_-_107221405 0.167 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr4_+_70831387 0.166 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr7_+_2524022 0.166 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_+_103677388 0.162 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr3_-_158695832 0.146 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr3_+_2528272 0.146 CNTN4
contactin 4
chr11_+_17697685 0.143 NM_002478
MYOD1
myogenic differentiation 1
chr14_-_94306104 0.143 NM_173849
GSC
goosecoid homeobox
chr8_-_42742729 0.143 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr6_+_130381408 0.141 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr2_-_190635566 0.138 NM_005259
MSTN
myostatin
chr4_-_138673078 0.128 NM_019035
PCDH18
protocadherin 18
chr3_+_70068440 0.128 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr1_-_42549347 0.126


chr11_+_59804634 0.122 NM_148975
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4
chr2_-_80385227 0.122 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr1_+_145892190 0.111 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr11_-_117640407 0.103 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr4_-_90197140 0.096 NM_014883
FAM13A
family with sequence similarity 13, member A
chr3_-_25658829 0.095 TOP2B
topoisomerase (DNA) II beta 180kDa
chr3_+_182900081 0.094 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr1_-_103269356 0.088 COL11A1
collagen, type XI, alpha 1
chr1_+_158426908 0.088 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_-_156635879 0.082 NM_001004475
OR10T2
olfactory receptor, family 10, subfamily T, member 2
chr11_+_112337199 0.081 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr10_+_32896656 0.079 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr2_+_143351536 0.075 NM_001032998
NM_003937
KYNU

kynureninase

chr11_-_128567302 0.075 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr3_-_69381995 0.074 FRMD4B
FERM domain containing 4B
chr3_-_127810087 0.072 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr17_+_18027816 0.071 ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr21_-_34820916 0.070 NM_203418
RCAN1
regulator of calcineurin 1
chr5_+_175041069 0.069 NM_022304
HRH2
histamine receptor H2
chr6_+_155626838 0.065 NM_001001346
CLDN20
claudin 20
chr6_+_62341966 0.063 NM_001190706
MTRNR2L9
MT-RNR2-like 9
chr1_+_242582559 0.062 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr4_-_138673014 0.062 PCDH18
protocadherin 18
chr12_+_15590811 0.061 PTPRO
protein tyrosine phosphatase, receptor type, O
chr10_+_18729518 0.059 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_-_9683462 0.059 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr16_+_54072969 0.059 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr14_+_75058591 0.059 BATF
basic leucine zipper transcription factor, ATF-like
chr13_-_33148899 0.053 STARD13
StAR-related lipid transfer (START) domain containing 13
chr10_-_52315390 0.052 A1CF
APOBEC1 complementation factor
chr12_-_55979413 0.052


chr6_-_166960690 0.052 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_28892366 0.051 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr8_+_92330691 0.051 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr4_-_66218777 0.049 EPHA5
EPH receptor A5
chr8_+_22266256 0.047 PIWIL2
piwi-like 2 (Drosophila)
chr6_-_50039776 0.047 NM_001037499
DEFB114
defensin, beta 114
chr4_-_100284395 0.047 NM_000670
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr2_-_80384997 0.047 NM_178839
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr3_-_166278969 0.045 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr4_+_169654742 0.044 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr14_+_66901237 0.044 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr16_+_47965308 0.043 NM_144602
C16orf78
chromosome 16 open reading frame 78
chr3_-_102522093 0.042 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr4_-_164614335 0.041 NM_032136
TKTL2
transketolase-like 2
chr2_+_189547358 0.041 COL3A1
collagen, type III, alpha 1
chr11_-_20138445 0.041 NM_001029865
DBX1
developing brain homeobox 1
chr6_-_33016561 0.040 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr15_+_97990705 0.040 NM_001130928
MEF2A
myocyte enhancer factor 2A
chrX_+_79562601 0.040 NM_152630
FAM46D
family with sequence similarity 46, member D
chr4_-_123596921 0.040 NM_000586
IL2
interleukin 2
chrX_+_107174855 0.040 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr4_-_169476391 0.039 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr2_+_128119908 0.039 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr20_+_58004811 0.038 NM_021810
CDH26
cadherin 26
chr15_-_40236061 0.038 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr8_+_9450832 0.038 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr11_-_33870411 0.038 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_65013070 0.038 LOC400958
hypothetical LOC400958
chr8_+_9450800 0.037 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_-_156013487 0.036 NM_030764
FCRL2
Fc receptor-like 2
chr11_-_17147863 0.035 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr3_+_110024234 0.034 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr6_+_64289585 0.034 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr14_+_101345878 0.034 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr9_+_66197108 0.034


chr11_+_59920062 0.034 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr11_+_86710076 0.033 TMEM135
transmembrane protein 135
chr10_-_50066386 0.033 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr9_-_205892 0.032 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr11_-_5279750 0.032 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr11_-_117640078 0.032


chr10_-_48036698 0.032 NM_016204
GDF2
growth differentiation factor 2
chr6_+_55300225 0.032 NM_207410
GFRAL
GDNF family receptor alpha like
chr14_+_31868229 0.032 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_28458546 0.032 NM_031459
SESN2
sestrin 2
chrX_-_23835868 0.031 NM_024122
APOO
apolipoprotein O
chr12_+_100394787 0.031 NM_152323
SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr3_+_2117246 0.031 NM_175607
CNTN4
contactin 4
chr14_-_59264044 0.031 NM_206857
RTN1
reticulon 1
chr1_-_153916221 0.031 NM_001198899
YY1AP1
YY1 associated protein 1
chr6_-_52818851 0.030 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr3_-_158704056 0.029 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr21_-_36836767 0.029 NM_001146078
CLDN14
claudin 14
chr16_+_6763810 0.028 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_-_66535457 0.028 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr15_-_70350609 0.028 NM_020214
PARP6
poly (ADP-ribose) polymerase family, member 6
chr7_+_141457977 0.027 LOC93432
maltase-glucoamylase-like pseudogene
chr2_-_20390601 0.027 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr11_-_30910074 0.027 NM_020869
DCDC5
doublecortin domain containing 5
chr6_-_112033752 0.026 TRAF3IP2
TRAF3 interacting protein 2
chr10_-_92671005 0.026 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_150653351 0.025 NM_016190
CRNN
cornulin
chr7_+_116447527 0.024 ST7
suppression of tumorigenicity 7
chr5_-_24535386 0.024 NM_001190450
CDH10
cadherin 10, type 2 (T2-cadherin)
chr6_+_155579788 0.023 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr4_+_5577783 0.023 NM_005750
C4orf6
chromosome 4 open reading frame 6
chrX_+_7147471 0.022 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr11_-_117640166 0.022 MPZL2
myelin protein zero-like 2
chr7_+_1239078 0.021 NM_001080461
UNCX
UNC homeobox
chr11_-_55815113 0.021 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr1_+_144595224 0.021 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr8_-_17787342 0.020 FGL1
fibrinogen-like 1
chr6_+_132901119 0.020 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr10_-_52315436 0.020 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr19_+_54708302 0.020 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_+_113200696 0.019 NM_001008273
TAGLN3
transgelin 3
chr7_+_113853790 0.019 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr17_-_36165050 0.018 NM_181534
KRT25
keratin 25
chr14_-_106249999 0.018 IGHA1
immunoglobulin heavy constant alpha 1
chr1_-_198643885 0.018 ZNF281
zinc finger protein 281
chr18_+_59705918 0.018 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr17_-_71448700 0.017 NM_001080542
FBF1
Fas (TNFRSF6) binding factor 1
chr22_+_39789945 0.016


chr13_+_47948586 0.016 RB1
retinoblastoma 1
chr15_-_64644758 0.016 NM_207338
LCTL
lactase-like
chr13_-_40491405 0.016 ELF1
E74-like factor 1 (ets domain transcription factor)
chr21_-_30642794 0.016 NM_181624
KRTAP23-1
keratin associated protein 23-1
chr3_-_48634192 0.016 NM_001008269
TMEM89
transmembrane protein 89
chr12_+_91620749 0.015 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_-_230717850 0.015 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr6_+_28425666 0.015 NM_024493
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr3_-_168674502 0.015 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr7_-_99612757 0.015 NM_152742
GPC2
glypican 2
chr1_-_27825633 0.015 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr8_+_23483422 0.014 SLC25A37
solute carrier family 25, member 37
chrX_+_43400350 0.014 NM_000240
MAOA
monoamine oxidase A
chr7_-_44547382 0.014 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr7_+_50318801 0.013 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr12_-_15706340 0.013 EPS8
epidermal growth factor receptor pathway substrate 8
chr17_+_12510030 0.013 MYOCD
myocardin
chr1_+_198263352 0.013 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr5_-_56814310 0.013 NM_001017992
ACTBL2
actin, beta-like 2
chr4_+_74499651 0.012 ALB
albumin
chr16_-_20246309 0.012 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr11_-_4371463 0.012 NM_003141
TRIM21
tripartite motif containing 21
chr10_-_98311813 0.011 TM9SF3
transmembrane 9 superfamily member 3
chr6_-_166960649 0.011 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_-_30032649 0.011 NM_017946
FKBP14
FK506 binding protein 14, 22 kDa
chr4_+_74520796 0.011 NM_001134
AFP
alpha-fetoprotein
chr6_+_160462852 0.011 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr1_+_175406685 0.011 FAM5B
family with sequence similarity 5, member B
chr11_+_89403921 0.011 NM_001195234
TRIM49
TRIM49L2
tripartite motif containing 49
tripartite motif containing 49-like 2
chr1_+_28134090 0.010 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr3_-_25654659 0.010 TOP2B
topoisomerase (DNA) II beta 180kDa
chr6_+_161043214 0.009 NM_000301
NM_001168338
PLG

plasminogen

chr10_+_5126589 0.009 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr9_-_21067804 0.009 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr6_-_112034166 0.008 NM_001164281
NM_147686
TRAF3IP2

TRAF3 interacting protein 2

chr8_-_134156437 0.008 SLA
Src-like-adaptor
chr19_-_51829778 0.008 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr4_-_57242492 0.008 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr3_+_99350859 0.008 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr19_-_45611110 0.008 NM_020956
NM_181882
PRX

periaxin

chr7_+_101810018 0.008


chr9_+_131937163 0.008 GPR107
G protein-coupled receptor 107
chr1_+_196874839 0.008 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_+_18305740 0.008 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr2_+_108571177 0.007 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_173911467 0.007 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr20_-_19981005 0.007 CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr15_-_53349775 0.007 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr1_-_45862225 0.007 NM_001114938
NM_001190182
CCDC17

coiled-coil domain containing 17

chr5_-_111119846 0.007 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr1_-_108032645 0.007 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr16_+_4322225 0.006 NM_032575
GLIS2
GLIS family zinc finger 2
chr3_+_154362726 0.006 RAP2B
RAP2B, member of RAS oncogene family
chr19_+_56766342 0.006 NM_007147
ZNF175
zinc finger protein 175
chr8_-_52884456 0.006 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr10_+_5126613 0.005 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_-_23998515 0.005 NM_001127621
GALE
UDP-galactose-4-epimerase
chr8_-_86477585 0.005 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr11_-_16454493 0.005 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr18_+_44319365 0.004 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr16_+_31178812 0.004 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr18_+_3437607 0.004 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr11_+_59580705 0.004 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chrX_+_43400475 0.004 MAOA
monoamine oxidase A

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.