Motif ID: ZBTB6.p2

Z-value: 1.552


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6



Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_37569962 2.145 NM_014293
NPTXR
neuronal pentraxin receptor
chr2_-_233060774 2.130 NM_004826
ECEL1
endothelin converting enzyme-like 1
chr14_+_28306633 1.968 FOXG1
forkhead box G1
chr8_+_104582151 1.818 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr10_-_99780574 1.708 NM_018058
CRTAC1
cartilage acidic protein 1
chr8_-_21702273 1.640 NM_001165038
NM_001165039
NM_001495
GFRA2


GDNF family receptor alpha 2


chr3_-_62835601 1.484


chr20_-_4177519 1.448 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr14_-_59407103 1.436 NM_021136
RTN1
reticulon 1
chr15_+_39573363 1.282 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr12_+_47975168 1.276 NM_006262
PRPH
peripherin
chr13_-_24643620 1.166 FAM123A
family with sequence similarity 123A
chr15_-_27650218 1.118 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr22_-_37569679 1.105


chr2_-_217267742 1.098 IGFBP5
insulin-like growth factor binding protein 5
chr14_+_58174489 1.074 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr3_-_159306532 1.073 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr10_+_24023680 1.058 NM_001098500
KIAA1217
KIAA1217
chr3_-_171786468 1.058 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr5_-_134397740 1.014 NM_002653
PITX1
paired-like homeodomain 1
chr12_-_79855580 0.988 LIN7A
lin-7 homolog A (C. elegans)
chr11_+_17714070 0.985 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr5_+_167889123 0.975


chr19_+_44697592 0.969 NM_182704
SELV
selenoprotein V
chr2_-_230287442 0.967 NM_139072
DNER
delta/notch-like EGF repeat containing
chr13_-_24643778 0.947 NM_152704
NM_199138
FAM123A

family with sequence similarity 123A

chrX_-_50230329 0.939 NM_001013742
DGKK
diacylglycerol kinase, kappa
chr9_+_70509925 0.939 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr2_+_104838177 0.927 NM_006236
POU3F3
POU class 3 homeobox 3
chr16_-_85099941 0.925 LOC400550
hypothetical LOC400550
chr8_+_63324053 0.924 NM_173688
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr19_-_54618410 0.923 NM_178449
PTH2
parathyroid hormone 2
chr9_-_103540038 0.921 GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr3_+_148609841 0.896 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr12_-_79855618 0.890 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr3_-_48675321 0.887 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr9_+_125813849 0.886 LHX2
LIM homeobox 2
chr17_+_31082791 0.880 NM_033315
RASL10B
RAS-like, family 10, member B
chr8_-_37943143 0.865 NM_000025
ADRB3
adrenergic, beta-3-, receptor
chr13_+_87122778 0.859 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr10_-_99780336 0.839 CRTAC1
cartilage acidic protein 1
chr13_-_37341859 0.827 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr5_-_63293715 0.827 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr15_-_39593285 0.821 NM_001135685
NM_002344
NM_206961
LTK


leukocyte receptor tyrosine kinase


chr3_+_161426322 0.819 LOC401097
hypothetical protein LOC401097
chr11_+_46256161 0.817 CREB3L1
cAMP responsive element binding protein 3-like 1
chr20_+_60918836 0.813 NM_001853
COL9A3
collagen, type IX, alpha 3
chr2_+_154436670 0.812 NM_052917
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr10_-_88116181 0.801 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr1_+_229365296 0.797 NM_001004342
TRIM67
tripartite motif containing 67
chr3_+_182912769 0.794 SOX2
SRY (sex determining region Y)-box 2
chr11_+_46256130 0.794 CREB3L1
cAMP responsive element binding protein 3-like 1
chr5_-_146237826 0.786 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr12_+_109956210 0.784 NM_015267
CUX2
cut-like homeobox 2
chr5_-_63293301 0.778 NM_000524
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr10_+_116843108 0.774 NM_207303
ATRNL1
attractin-like 1
chr16_+_1979959 0.773 NM_004209
SYNGR3
synaptogyrin 3
chr1_-_92721633 0.763 GFI1
growth factor independent 1 transcription repressor
chr5_-_146238336 0.763 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr1_-_92721943 0.763 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr4_-_111777956 0.756 NM_153426
NM_153427
PITX2

paired-like homeodomain 2

chr19_-_54267932 0.750 NM_031886
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr8_-_25958556 0.743 EBF2
early B-cell factor 2
chr7_-_100331417 0.740 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr8_-_133561738 0.737 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr5_+_149526533 0.735 NM_001804
CDX1
caudal type homeobox 1
chr19_-_54267690 0.724 KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr8_-_144583718 0.724 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr11_+_63815348 0.722 NM_033310
KCNK4
potassium channel, subfamily K, member 4
chr9_+_86474553 0.721 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr20_+_13150417 0.717 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr8_-_133561933 0.717 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr1_-_40555511 0.712 NM_001852
COL9A2
collagen, type IX, alpha 2
chr10_+_101079099 0.710 CNNM1
cyclin M1
chr5_-_132976094 0.704 FSTL4
follistatin-like 4
chr9_+_86474500 0.703 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr1_-_40555413 0.699 COL9A2
collagen, type IX, alpha 2
chr11_-_63014986 0.699 NM_001146728
NM_001146729
NM_054108
HRASLS5


HRAS-like suppressor family, member 5


chr9_+_138858687 0.695 NM_001080482
C9orf172
chromosome 9 open reading frame 172
chr2_+_120018494 0.681 NM_001029996
PCDP1
primary ciliary dyskinesia protein 1
chr21_-_38210531 0.678 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr3_+_148610516 0.673 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr5_-_132976121 0.671 NM_015082
FSTL4
follistatin-like 4
chr21_+_34963557 0.657 NM_053277
CLIC6
chloride intracellular channel 6
chr9_-_103289154 0.656 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr2_-_200028977 0.654 SATB2
SATB homeobox 2
chr2_+_231968578 0.653 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr1_-_40555568 0.653 COL9A2
collagen, type IX, alpha 2
chr4_+_61749540 0.647 LPHN3
latrophilin 3
chr2_-_27384617 0.643 NM_003353
UCN
urocortin
chr3_-_135097111 0.639 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr19_+_17923110 0.638 NM_002248
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr22_-_37180958 0.637 NM_152868
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr9_+_137119339 0.632 OLFM1
olfactomedin 1
chr14_+_28305922 0.625 NM_005249
FOXG1
forkhead box G1
chr4_-_163304567 0.623 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chr9_+_137119334 0.618 OLFM1
olfactomedin 1
chr11_+_46255737 0.617 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr10_+_101282679 0.614 NM_145285
NKX2-3
NK2 transcription factor related, locus 3 (Drosophila)
chr16_+_54782802 0.612 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr11_-_75057062 0.610 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr5_-_72780107 0.609 NM_004472
FOXD1
forkhead box D1
chr4_-_109308893 0.608 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr1_-_92722088 0.605 GFI1
growth factor independent 1 transcription repressor
chr7_-_45927263 0.601 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr1_-_182273114 0.597 GLT25D2
glycosyltransferase 25 domain containing 2
chr17_+_7549138 0.597 NM_001406
EFNB3
ephrin-B3
chr19_-_60383280 0.591 NM_003180
SYT5
synaptotagmin V
chr9_-_90983195 0.589 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr17_-_33178987 0.583 HNF1B
HNF1 homeobox B
chr1_-_202921103 0.579 NM_006338
NM_201630
LRRN2

leucine rich repeat neuronal 2

chr3_-_13436725 0.578 NUP210
nucleoporin 210kDa
chr12_+_50686990 0.578 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr12_-_56418295 0.578 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr12_-_51281482 0.573 NM_001146225
NM_001146226
NM_080747
KRT72


keratin 72


chr5_-_148014282 0.573 HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr3_-_159306214 0.572


chr6_+_14033076 0.571 NM_001165032
NM_152737
RNF182

ring finger protein 182

chrX_-_138114100 0.569 FGF13
fibroblast growth factor 13
chr10_+_106390848 0.568 NM_014978
SORCS3
sortilin-related VPS10 domain containing receptor 3
chr11_-_78829342 0.567 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr7_-_20791907 0.566


chr20_-_9767406 0.566 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chrX_-_99551926 0.565 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr1_+_237616457 0.564 CHRM3
cholinergic receptor, muscarinic 3
chr9_+_86474393 0.564 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr9_+_86474457 0.563 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr16_+_65754788 0.561 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr5_+_89890366 0.561 NM_032119
GPR98
G protein-coupled receptor 98
chr10_-_103525646 0.559 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr9_+_86474445 0.557 NM_001007097
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr1_-_103346639 0.554 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr5_+_140200995 0.554 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr3_-_62836052 0.553 NM_003716
NM_183393
NM_183394
CADPS


Ca++-dependent secretion activator


chr9_-_88159076 0.552 ZCCHC6
zinc finger, CCHC domain containing 6
chr12_-_116021473 0.551 NM_001168325
NM_017899
TESC

tescalcin

chr20_-_61108831 0.551 NM_080606
BHLHE23
basic helix-loop-helix family, member e23
chr11_-_71632864 0.551 NM_005169
PHOX2A
paired-like homeobox 2a
chr15_-_30798417 0.551


chr4_+_1764802 0.549 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr11_+_20647692 0.549 NM_006157
NM_201551
NELL1

NEL-like 1 (chicken)

chr7_+_154943466 0.548 NM_001427
EN2
engrailed homeobox 2
chr5_-_134397470 0.544 PITX1
paired-like homeodomain 1
chr14_+_36200815 0.544 PAX9
paired box 9
chr13_+_27392136 0.542 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr8_-_133562185 0.542 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr10_+_134823925 0.541 NM_152643
KNDC1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr5_-_148013908 0.540 NM_000870
HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr2_-_154043403 0.536 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_26245031 0.535 NM_001004434
NM_032513
SLC30A2

solute carrier family 30 (zinc transporter), member 2

chr4_-_66218777 0.534 EPHA5
EPH receptor A5
chr8_+_56177567 0.534 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr11_-_71632695 0.533 PHOX2A
paired-like homeobox 2a
chr22_+_27931685 0.533 NM_133455
EMID1
EMI domain containing 1
chr10_+_134901397 0.531 NM_014468
VENTX
VENT homeobox homolog (Xenopus laevis)
chr7_-_19123765 0.531 TWIST1
twist homolog 1 (Drosophila)
chr7_-_12410376 0.529 NM_001135924
VWDE
von Willebrand factor D and EGF domains
chr22_-_42589543 0.526 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr14_+_105024576 0.526 CRIP1
cysteine-rich protein 1 (intestinal)
chr18_+_46340400 0.524 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr17_+_11085464 0.524 NM_001173461
NM_001173462
NM_207386
SHISA6


shisa homolog 6 (Xenopus laevis)


chr11_-_31789168 0.523 PAX6
paired box 6
chr21_+_37300732 0.523 NM_018962
DSCR6
Down syndrome critical region gene 6
chr10_+_106391032 0.520 SORCS3
sortilin-related VPS10 domain containing receptor 3
chr17_+_4434582 0.520 NM_001114974
SMTNL2
smoothelin-like 2
chr7_-_15692551 0.516 MEOX2
mesenchyme homeobox 2
chr19_+_38485583 0.515 LOC80054
hypothetical LOC80054
chr5_+_79021401 0.512 NM_153610
CMYA5
cardiomyopathy associated 5
chr10_-_99084417 0.512 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr11_+_17697685 0.511 NM_002478
MYOD1
myogenic differentiation 1
chr4_+_115739006 0.508 NM_001128174
UGT8
UDP glycosyltransferase 8
chr6_+_1257674 0.508 NM_033260
FOXQ1
forkhead box Q1
chr6_+_99389318 0.504 POU3F2
POU class 3 homeobox 2
chr2_-_219882302 0.504 NM_002846
PTPRN
protein tyrosine phosphatase, receptor type, N
chr10_+_104619199 0.504 NM_020682
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr1_-_103346482 0.504 COL11A1
collagen, type XI, alpha 1
chr4_+_40953698 0.502 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr14_-_64359565 0.501 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr21_+_33364420 0.499 OLIG1
oligodendrocyte transcription factor 1
chr21_+_33364316 0.498 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr3_+_142252890 0.497 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr19_+_50693570 0.496 NM_001080401
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr11_+_268569 0.495 NM_138329
NLRP6
NLR family, pyrin domain containing 6
chr12_+_129388543 0.493 PIWIL1
piwi-like 1 (Drosophila)
chr7_-_4965270 0.492 NM_001100600
NM_198403
MMD2

monocyte to macrophage differentiation-associated 2

chr14_+_103675194 0.489 KIF26A
kinesin family member 26A
chr2_+_219432789 0.487 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr1_+_41022066 0.486 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr4_-_111763356 0.485 PITX2
paired-like homeodomain 2
chr18_+_61568825 0.484 CDH7
cadherin 7, type 2
chr10_+_112394094 0.484 NM_001134363
RBM20
RNA binding motif protein 20
chr3_+_142253102 0.483 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr11_-_118799058 0.482 THY1
Thy-1 cell surface antigen
chr6_+_19946591 0.482


chr9_-_85342868 0.479 NM_174938
FRMD3
FERM domain containing 3
chr11_-_118799452 0.477 NM_006288
THY1
Thy-1 cell surface antigen
chr3_-_135096986 0.477 RAB6B
RAB6B, member RAS oncogene family
chr3_+_142253432 0.477 NM_080862
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_-_218168548 0.474 NM_018713
SLC30A10
solute carrier family 30, member 10
chr4_+_40953666 0.471 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.