Motif ID: ZIC1..3.p2

Z-value: 2.847


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)



Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_28306633 6.123 FOXG1
forkhead box G1
chr4_-_174687104 4.710 HAND2
heart and neural crest derivatives expressed 2
chrX_-_107866262 4.583 NM_003604
IRS4
insulin receptor substrate 4
chr14_-_103058568 4.204 CKB
creatine kinase, brain
chr1_-_38285033 3.620 NM_002699
POU3F1
POU class 3 homeobox 1
chr4_-_174686918 3.275 HAND2
heart and neural crest derivatives expressed 2
chr11_-_75056761 3.096 MAP6
microtubule-associated protein 6
chr10_-_95350949 3.074 NM_006744
RBP4
retinol binding protein 4, plasma
chr12_-_42231990 2.950 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr13_-_52320774 2.873 NM_002590
NM_032949
PCDH8

protocadherin 8

chr16_-_47872880 2.795


chr9_+_99656013 2.776


chr19_+_10404110 2.657 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr8_+_1937711 2.577 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr14_+_100362236 2.572 MEG3
maternally expressed 3 (non-protein coding)
chr14_-_103058865 2.560 NM_001823
CKB
creatine kinase, brain
chr11_-_75057062 2.552 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr14_+_100362204 2.543 MEG3
maternally expressed 3 (non-protein coding)
chr9_+_78824390 2.535 NM_001013735
FOXB2
forkhead box B2
chr16_-_47872973 2.376 CBLN1
cerebellin 1 precursor
chr2_+_219991342 2.323 NM_001927
DES
desmin
chr17_-_72045218 2.319 NM_134268
CYGB
cytoglobin
chr7_-_27191287 2.311 NM_005523
HOXA11
homeobox A11
chr3_-_73756668 2.307 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr7_-_150737980 2.291 NM_198285
WDR86
WD repeat domain 86
chr20_+_36786540 2.229 SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr2_+_137239583 2.213 THSD7B
thrombospondin, type I, domain containing 7B
chr11_-_75057299 2.164 MAP6
microtubule-associated protein 6
chr4_+_72271218 2.133 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr20_+_36786518 2.125 NM_080552
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr17_-_25642962 2.123 NM_000386
BLMH
bleomycin hydrolase
chr8_+_31616809 2.074 NM_013962
NRG1
neuregulin 1
chr2_+_15999599 2.042 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_+_171619346 2.035 NM_005602
CLDN11
claudin 11
chr16_+_54247852 2.007 NM_001043
NM_001172504
SLC6A2

solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

chr3_-_130807865 1.994 NM_015103
PLXND1
plexin D1
chrX_+_106057984 1.990 CLDN2
claudin 2
chr14_+_100263066 1.972 DLK1
delta-like 1 homolog (Drosophila)
chr19_-_51856129 1.964 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_-_85529884 1.941 TBX18
T-box 18
chr11_+_111288669 1.872 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr13_+_32488477 1.854 NM_004795
KL
klotho
chr9_-_72673753 1.838 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr5_-_132189762 1.827 NM_133456
SHROOM1
shroom family member 1
chr5_+_71438796 1.826 NM_005909
MAP1B
microtubule-associated protein 1B
chr2_+_96355661 1.822 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chrX_-_30237403 1.807 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr15_+_58083798 1.779 FOXB1
forkhead box B1
chr18_+_53170718 1.759 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr16_+_54247400 1.753 SLC6A2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chrX_+_90576252 1.751 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr2_+_200031333 1.741


chr4_+_4912272 1.736 NM_002448
MSX1
msh homeobox 1
chr12_+_56140184 1.723 NM_001160045
NM_001167609
NM_005269
GLI1


GLI family zinc finger 1


chr11_+_111288686 1.719 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr22_-_36809094 1.712 NM_013356
SLC16A8
solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
chr15_+_58083737 1.708


chr18_-_30057166 1.703 NOL4
nucleolar protein 4
chrX_-_114374860 1.698 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chrX_+_72140076 1.691 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr14_+_64077171 1.691 HSPA2
heat shock 70kDa protein 2
chr11_+_19691397 1.687 NM_145117
NM_182964
NAV2

neuron navigator 2

chr5_-_577444 1.679 NM_004174
SLC9A3
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chr15_+_58083712 1.641 NM_012182
FOXB1
forkhead box B1
chr3_-_166397142 1.628 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr16_+_85158357 1.628 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr10_-_99780574 1.623 NM_018058
CRTAC1
cartilage acidic protein 1
chrX_+_101792949 1.614 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr17_-_47592159 1.610 NM_001082533
CA10
carbonic anhydrase X
chr7_-_4867963 1.606 NM_020144
PAPOLB
poly(A) polymerase beta (testis specific)
chr8_+_19841209 1.601 LPL
lipoprotein lipase
chr6_-_33268177 1.573 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr5_+_167889123 1.558


chr2_-_133144094 1.558 LYPD1
LY6/PLAUR domain containing 1
chr15_+_72208751 1.552 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_-_132318741 1.550 OPCML
opioid binding protein/cell adhesion molecule-like
chr17_-_47592341 1.539 NM_001082534
CA10
carbonic anhydrase X
chr7_-_27180398 1.539 NM_018951
HOXA10
homeobox A10
chr18_-_30057512 1.530 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr9_-_138757175 1.526 NM_001001712
LCN10
lipocalin 10
chr17_+_56884560 1.526 TBX4
T-box 4
chr12_-_3732478 1.521 EFCAB4B
EF-hand calcium binding domain 4B
chr10_-_62373828 1.514 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr17_-_47591949 1.511 CA10
carbonic anhydrase X
chr2_+_176695658 1.493 NM_014213
HOXD9
homeobox D9
chr1_-_39877883 1.486 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr9_-_121171400 1.482 NM_014618
DBC1
deleted in bladder cancer 1
chr14_+_28305922 1.472 NM_005249
FOXG1
forkhead box G1
chr3_+_63238854 1.463 NM_001130003
SYNPR
synaptoporin
chr2_+_15999396 1.461 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr17_-_6887965 1.459 NM_153357
SLC16A11
solute carrier family 16, member 11 (monocarboxylic acid transporter 11)
chr3_+_148610516 1.459 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr3_+_134601479 1.453 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr21_+_33364420 1.447 OLIG1
oligodendrocyte transcription factor 1
chrX_-_24941098 1.444 ARX
aristaless related homeobox
chr1_-_39877928 1.437 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chrX_-_107221405 1.423 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr22_-_43783449 1.422 PHF21B
PHD finger protein 21B
chr1_+_11674365 1.422 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr15_+_72209039 1.415 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chrX_+_107221552 1.407 NM_052936
NM_178270
ATG4A

ATG4 autophagy related 4 homolog A (S. cerevisiae)

chr3_+_185580554 1.407 NM_003741
CHRD
chordin
chr14_+_100270222 1.402 DLK1
delta-like 1 homolog (Drosophila)
chr16_+_66244314 1.400 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr12_-_43556220 1.383 NELL2
NEL-like 2 (chicken)
chr3_+_49566901 1.379 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr5_-_174803768 1.369 NM_000794
DRD1
dopamine receptor D1
chr17_+_56832492 1.368 TBX2
T-box 2
chr12_-_3732614 1.362 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr17_-_47591691 1.361 CA10
carbonic anhydrase X
chr8_+_19841120 1.360 LPL
lipoprotein lipase
chr8_-_132122016 1.358 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr4_+_156808261 1.350 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr19_-_13478037 1.350 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_+_19510098 1.345 CILP2
cartilage intermediate layer protein 2
chr1_-_29321599 1.342 NM_001171868
TMEM200B
transmembrane protein 200B
chr5_-_83715947 1.339 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr17_+_70244945 1.332 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chrX_+_101853912 1.330 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr1_-_90955365 1.326 NM_020063
BARHL2
BarH-like homeobox 2
chr13_-_24643620 1.318 FAM123A
family with sequence similarity 123A
chr14_-_50631407 1.313 TRIM9
tripartite motif containing 9
chr12_-_43556338 1.309 NELL2
NEL-like 2 (chicken)
chr22_-_42589543 1.302 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr3_+_3816079 1.300 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr11_-_126375864 1.298 KIRREL3
kin of IRRE like 3 (Drosophila)
chr6_+_101948102 1.293


chr19_+_19510056 1.291 NM_153221
CILP2
cartilage intermediate layer protein 2
chr9_+_135389698 1.285 NM_014694
ADAMTSL2
ADAMTS-like 2
chr12_+_79625538 1.283 NM_002469
MYF6
myogenic factor 6 (herculin)
chr2_-_144991386 1.274 ZEB2
zinc finger E-box binding homeobox 2
chrX_-_134013644 1.273 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr7_+_44110470 1.268 NM_001129
AEBP1
AE binding protein 1
chr15_+_39573363 1.258 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chrX_-_20044670 1.253 NM_001168467
MAP7D2
MAP7 domain containing 2
chr11_+_122806196 1.251 LOC100128242
hypothetical LOC100128242
chr16_+_65840275 1.248 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr12_+_5411534 1.243 NM_001102654
NTF3
neurotrophin 3
chr20_-_22512893 1.236 FOXA2
forkhead box A2
chrX_-_53367246 1.230 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr8_+_19841010 1.228 LPL
lipoprotein lipase
chr7_-_150306169 1.228 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_-_67163600 1.226 NM_005995
TBX10
T-box 10
chr17_+_70244553 1.215 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr6_+_72653126 1.200 RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_74595073 1.196 NM_016170
TLX2
T-cell leukemia homeobox 2
chr12_-_131256525 1.192 NM_021808
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr2_-_74580173 1.191 LBX2
ladybird homeobox 2
chrX_-_13866565 1.190 NM_001001994
GPM6B
glycoprotein M6B
chr22_-_17891777 1.187 CLDN5
claudin 5
chr12_-_56312696 1.183 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr11_-_32413486 1.182 WT1
Wilms tumor 1
chr9_-_35948150 1.177 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr3_+_53504070 1.177 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr20_-_22514092 1.164 NM_153675
FOXA2
forkhead box A2
chr11_-_2115086 1.162 IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_112273464 1.153 NM_015480
PVRL3
poliovirus receptor-related 3
chr11_+_67871999 1.152 LRP5
low density lipoprotein receptor-related protein 5
chr16_+_1979959 1.152 NM_004209
SYNGR3
synaptogyrin 3
chr13_-_24643778 1.151 NM_152704
NM_199138
FAM123A

family with sequence similarity 123A

chr11_-_27697768 1.149 NM_001143807
BDNF
brain-derived neurotrophic factor
chr7_+_68702252 1.147 AUTS2
autism susceptibility candidate 2
chr4_-_5940893 1.146 CRMP1
collapsin response mediator protein 1
chr21_+_33364316 1.145 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr19_-_11452439 1.144 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr8_+_1909437 1.141 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr5_-_44424423 1.137 NM_004465
FGF10
fibroblast growth factor 10
chr14_+_101097440 1.136 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr17_+_42686217 1.135 ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr2_-_27339278 1.132 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr1_+_168899936 1.131 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr6_+_99389318 1.129 POU3F2
POU class 3 homeobox 2
chr12_+_117903682 1.126 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr16_-_265868 1.121 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr11_+_43920385 1.114 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr12_-_80676562 1.113 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr7_+_44110527 1.113 AEBP1
AE binding protein 1
chr20_-_1922393 1.107 NM_001190900
PDYN
prodynorphin
chrX_-_13866366 1.105


chr9_+_831689 1.102 NM_021951
DMRT1
doublesex and mab-3 related transcription factor 1
chr1_-_111018798 1.102 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr3_+_112273352 1.100 PVRL3
poliovirus receptor-related 3
chr12_-_21985433 1.086 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_+_19946591 1.084


chr11_-_289518 1.083 NM_001025295
IFITM5
interferon induced transmembrane protein 5
chr2_-_192767844 1.082 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr4_+_156807311 1.081 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr18_-_68685789 1.079 NM_138966
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr9_+_130909926 1.079


chr2_-_51112743 1.075 NRXN1
neurexin 1
chr10_-_132999973 1.074 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr22_-_17892001 1.071 CLDN5
claudin 5
chr6_-_166502119 1.070 NM_003181
T
T, brachyury homolog (mouse)
chr15_-_39593285 1.069 NM_001135685
NM_002344
NM_206961
LTK


leukocyte receptor tyrosine kinase


chr5_+_170779664 1.069 FGF18
fibroblast growth factor 18
chr14_+_100262916 1.068 DLK1
delta-like 1 homolog (Drosophila)
chr22_-_29231597 1.063 NM_001161368
NM_174977
SEC14L4

SEC14-like 4 (S. cerevisiae)

chrX_-_138114846 1.058 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr4_-_5941167 1.054 NM_001313
CRMP1
collapsin response mediator protein 1
chr9_-_103289154 1.050 NM_032342
C9orf125
chromosome 9 open reading frame 125

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.59 9.20e-12 GO:0048856 anatomical structure development
2.71 1.17e-11 GO:0048731 system development
2.36 3.56e-11 GO:0032502 developmental process
3.61 4.86e-11 GO:0007399 nervous system development
2.41 1.83e-10 GO:0007275 multicellular organismal development
4.59 3.16e-10 GO:0009888 tissue development
2.00 4.19e-10 GO:0032501 multicellular organismal process
7.00 2.41e-09 GO:0007420 brain development
2.84 8.51e-09 GO:0048869 cellular developmental process
2.86 1.20e-08 GO:0030154 cell differentiation
3.24 2.85e-08 GO:0009653 anatomical structure morphogenesis
5.31 1.60e-07 GO:0007417 central nervous system development
6.21 2.28e-07 GO:0048598 embryonic morphogenesis
3.89 2.49e-07 GO:0048468 cell development
4.44 3.42e-07 GO:0009790 embryo development
6.34 4.92e-07 GO:0007389 pattern specification process
2.76 6.21e-07 GO:0048513 organ development
8.77 2.95e-06 GO:0030900 forebrain development
5.02 7.80e-06 GO:0048646 anatomical structure formation involved in morphogenesis
6.45 1.19e-05 GO:0035295 tube development
7.02 1.27e-05 GO:0003002 regionalization
3.53 1.87e-05 GO:0050793 regulation of developmental process
5.66 6.67e-05 GO:0001501 skeletal system development
3.81 1.39e-04 GO:0045595 regulation of cell differentiation
4.84 5.02e-04 GO:0009792 embryo development ending in birth or egg hatching
18.55 7.16e-04 GO:0021536 diencephalon development
4.36 8.39e-04 GO:0051094 positive regulation of developmental process
25.30 1.23e-03 GO:0022029 telencephalon cell migration
7.23 1.25e-03 GO:0009952 anterior/posterior pattern formation
5.21 1.33e-03 GO:0048729 tissue morphogenesis
24.20 1.56e-03 GO:0021885 forebrain cell migration
3.70 1.78e-03 GO:0009887 organ morphogenesis
2.93 2.03e-03 GO:0007154 cell communication
4.57 2.40e-03 GO:0043009 chordate embryonic development
15.18 2.44e-03 GO:0001756 somitogenesis
3.29 2.81e-03 GO:2000026 regulation of multicellular organismal development
2.14 2.87e-03 GO:0051252 regulation of RNA metabolic process
4.50 2.94e-03 GO:0060429 epithelium development
2.16 3.01e-03 GO:0006355 regulation of transcription, DNA-dependent
3.37 3.53e-03 GO:0030182 neuron differentiation
5.73 3.61e-03 GO:0002009 morphogenesis of an epithelium
20.61 3.63e-03 GO:0009954 proximal/distal pattern formation
14.21 3.64e-03 GO:0061053 somite development
2.91 3.74e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.99 4.10e-03 GO:0022008 neurogenesis
4.70 4.12e-03 GO:0045597 positive regulation of cell differentiation
13.92 4.13e-03 GO:0019228 regulation of action potential in neuron
6.15 5.35e-03 GO:0048732 gland development
3.03 5.73e-03 GO:0048699 generation of neurons
18.55 6.27e-03 GO:0008589 regulation of smoothened signaling pathway
3.88 7.77e-03 GO:0072358 cardiovascular system development
3.88 7.77e-03 GO:0072359 circulatory system development
27.83 1.01e-02 GO:0021846 cell proliferation in forebrain
3.74 1.20e-02 GO:0019226 transmission of nerve impulse
3.74 1.20e-02 GO:0035637 multicellular organismal signaling
2.51 1.22e-02 GO:0051239 regulation of multicellular organismal process
3.69 1.40e-02 GO:0000904 cell morphogenesis involved in differentiation
1.93 1.41e-02 GO:0009889 regulation of biosynthetic process
3.33 1.43e-02 GO:0032989 cellular component morphogenesis
2.68 1.44e-02 GO:0010646 regulation of cell communication
3.91 1.44e-02 GO:0032583 regulation of gene-specific transcription
1.93 1.47e-02 GO:0048518 positive regulation of biological process
5.46 1.53e-02 GO:0048514 blood vessel morphogenesis
3.44 1.73e-02 GO:0048666 neuron development
10.60 2.04e-02 GO:0001508 regulation of action potential
1.40 2.06e-02 GO:0065007 biological regulation
23.43 2.10e-02 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway
4.73 2.18e-02 GO:0051960 regulation of nervous system development
47.70 2.33e-02 GO:0021854 hypothalamus development
47.70 2.33e-02 GO:0042693 muscle cell fate commitment
10.28 2.45e-02 GO:0035282 segmentation
1.91 2.52e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.91 2.52e-02 GO:0031326 regulation of cellular biosynthetic process
1.95 2.53e-02 GO:0010556 regulation of macromolecule biosynthetic process
5.76 2.69e-02 GO:0035239 tube morphogenesis
13.92 2.69e-02 GO:0001656 metanephros development
13.92 2.69e-02 GO:0021761 limbic system development
3.30 2.81e-02 GO:0000902 cell morphogenesis
13.58 3.05e-02 GO:0007272 ensheathment of neurons
13.58 3.05e-02 GO:0008366 axon ensheathment
1.95 3.30e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
7.72 3.37e-02 GO:0035107 appendage morphogenesis
7.72 3.37e-02 GO:0035108 limb morphogenesis
9.54 3.75e-02 GO:0048762 mesenchymal cell differentiation
1.93 3.96e-02 GO:0048522 positive regulation of cellular process
6.28 4.13e-02 GO:0045165 cell fate commitment
7.42 4.32e-02 GO:0048736 appendage development
7.42 4.32e-02 GO:0060173 limb development
2.92 4.51e-02 GO:0007267 cell-cell signaling
6.15 4.80e-02 GO:0043062 extracellular structure organization
1.89 4.98e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.03 1.26e-03 GO:0045202 synapse
5.06 1.43e-03 GO:0005667 transcription factor complex
1.59 1.50e-02 GO:0005886 plasma membrane
1.57 2.23e-02 GO:0071944 cell periphery
3.88 3.23e-02 GO:0044456 synapse part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.81 7.78e-09 GO:0001071 nucleic acid binding transcription factor activity
3.81 7.78e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
4.30 1.25e-07 GO:0043565 sequence-specific DNA binding
3.39 1.09e-06 GO:0030528 transcription regulator activity
5.03 1.44e-04 GO:0016563 transcription activator activity
9.28 1.86e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
4.46 3.08e-03 GO:0016564 transcription repressor activity
8.38 3.63e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
8.04 4.78e-03 GO:0016566 specific transcriptional repressor activity
5.17 1.16e-02 GO:0010843 promoter binding
4.96 1.58e-02 GO:0000975 regulatory region DNA binding
4.96 1.58e-02 GO:0001067 regulatory region nucleic acid binding
4.96 1.58e-02 GO:0044212 transcription regulatory region DNA binding
10.12 2.36e-02 GO:0008301 DNA bending activity
7.42 2.83e-02 GO:0003704 specific RNA polymerase II transcription factor activity